Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138133 (US8871783, 19) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.900 | -51.6 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138118 (US8871783, 4) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.10 | -49.5 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138136 (US8871783, 22) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.20 | -49.4 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138137 (US8871783, 23) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.90 | -48.7 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138117 (US8871783, 3) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.20 | -48.5 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138135 (US8871783, 21) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.60 | -48.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138139 (US8871783, 25) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4 | -47.9 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138131 (US8871783, 17) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.20 | -47.8 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138128 (US8871783, 14) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 13.4 | -44.9 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138115 (US8871783, 1) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 13.7 | -44.9 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138126 (US8871783, 12) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 14.9 | -44.7 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138140 (US8871783, 26) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 16.7 | -44.4 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138130 (US8871783, 16) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 17.1 | -44.3 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138116 (US8871783, 2) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 17.3 | -44.3 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138138 (US8871783, 24) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 21.9 | -43.7 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138132 (US8871783, 18) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 27 | -43.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138124 (US8871783, 10) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 35.8 | -42.5 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138134 (US8871783, 20) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 37.9 | -42.4 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138121 (US8871783, 7) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 39.3 | -42.3 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138129 (US8871783, 15) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 41.9 | -42.1 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138127 (US8871783, 13) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 61.7 | -41.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138123 (US8871783, 9) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 62 | -41.1 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138120 (US8871783, 6) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 64.1 | -41.1 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138125 (US8871783, 11) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 72.8 | -40.7 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138122 (US8871783, 8) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 104 | -39.9 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138119 (US8871783, 5) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 177 | -38.5 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM50026017 (2-Amino-N-(benzyl-cyano-methyl)-acetamide | CHEMBL...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1 | J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Mus musculus) | BDBM50147181 (3-{[1-(2-Amino-acetylamino)-3-methyl-butyl]-hydrox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay | Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Mus musculus) | BDBM50147182 (3-{[1-(2-Amino-acetylamino)-3-methyl-butyl]-hydrox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay | Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Mus musculus) | BDBM50147183 (3-{[(2-Amino-acetylamino)-phenyl-methyl]-hydroxy-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.76E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay | Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM50026018 (2-Amino-N-(1-benzyl-3-methanesulfonyl-allyl)-aceta...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1 | J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Mus musculus) | BDBM50147185 (3-{[1-(2-Amino-acetylamino)-3-phenyl-propyl]-hydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.87E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay | Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Mus musculus) | BDBM50147180 (3-{[(2-Amino-acetylamino)-phenyl-methyl]-hydroxy-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.88E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay | Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM50026015 (4-(2-Amino-acetylamino)-5-phenyl-pent-2-enoic acid...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1 | J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Mus musculus) | BDBM50147184 (3-{[1-(2-Amino-acetylamino)-3-phenyl-propyl]-hydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay | Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Mus musculus) | BDBM50147187 (3-{[1-(2-Amino-acetylamino)-2-phenyl-ethyl]-hydrox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay | Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Mus musculus) | BDBM50147186 (3-{[1-(2-Amino-acetylamino)-2-phenyl-ethyl]-hydrox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.14E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay | Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM50026027 (2-(2-Amino-acetylamino)-3-phenyl-propionamide | CH...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for Inhibition of dipeptidyl Dipeptidyl aminopeptidase 1 | J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr... | US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH US Patent | Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in... | US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH US Patent | Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ... | US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM50195247 (CHEMBL3936580) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.251 | n/a | n/a | n/a | n/a | n/a | n/a |
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED Curated by ChEMBL | Assay Description Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assay | J Med Chem 59: 9457-9472 (2016) Article DOI: 10.1021/acs.jmedchem.6b01127 BindingDB Entry DOI: 10.7270/Q2Z321K4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM633586 (N—((S)-1-cyano-2-(3-fluoro-4′-(pentafluoro-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr... | US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM50310682 ((S)-2-amino-N-((S)-1-cyano-2-(5-phenylthiophen-2-y...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada& Co. Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin C | Bioorg Med Chem Lett 19: 5392-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.114 BindingDB Entry DOI: 10.7270/Q298874W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH US Patent | Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in... | US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH US Patent | Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ... | US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM50502619 (CHEMBL4561264) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.398 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ... | ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr... | US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH US Patent | Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in... | US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M | |||||||||||
More data for this Ligand-Target Pair |
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