Compile Data Set for Download or QSAR

Found 1367 hits Enz. Inhib. hit(s) with all data for entry = 50034029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50120367 (CHEMBL3616695) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)nc1 Show InChI InChI=1S/C36H35F3N4O5/c1-4-5-6-29(22-7-9-23(10-8-22)35(46)40-18-17-33(44)45)43-30-19-24(25-12-16-32(48-3)41-21-25)11-14-27(30)34(42-43)28-20-26(36(37,38)39)13-15-31(28)47-2/h7-16,19-21,29H,4-6,17-18H2,1-3H3,(H,40,46)(H,44,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM235141 (US9359339, 43) Show SMILES CCC[C@@H](C(c1csc2c(Br)cc(C)cc12)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCCS(O)(=O)=O Show InChI InChI=1S/C29H29BrClNO4S2/c1-3-4-23(19-5-7-21(8-6-19)29(33)32-13-14-38(34,35)36)27(20-9-11-22(31)12-10-20)25-17-37-28-24(25)15-18(2)16-26(28)30/h5-12,15-17,23,27H,3-4,13-14H2,1-2H3,(H,32,33)(H,34,35,36)/t23-,27?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	25
Merck Sharp & Dohme Corp. US Patent					Assay Description A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...				US Patent US9359339 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VHC
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120371 (CHEMBL3616698) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C36H31F6N3O4/c1-3-4-5-29(20-6-8-21(9-7-20)35(48)43-15-14-32(46)47)45-30-18-22(23-16-27(37)33(39)28(38)17-23)10-12-25(30)34(44-45)26-19-24(36(40,41)42)11-13-31(26)49-2/h6-13,16-19,29H,3-5,14-15H2,1-2H3,(H,43,48)(H,46,47)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50244455 ((R)-3-{4-[1-(4-Cyclohex-1-enylphenyl)-3-(3,5-dichl...) Show SMILES O[C@H](CNC(=O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(cc2)C2=CCCCC2)cc1)C(O)=O |r,t:31| Show InChI InChI=1S/C30H29Cl2N3O5/c31-23-14-24(32)16-25(15-23)34-30(40)35(26-12-10-21(11-13-26)20-4-2-1-3-5-20)18-19-6-8-22(9-7-19)28(37)33-17-27(36)29(38)39/h4,6-16,27,36H,1-3,5,17-18H2,(H,33,37)(H,34,40)(H,38,39)/t27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to human cloned GluR expressed in BHK cells				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50396184 (REDIOCIDE A) Show SMILES CC(C)CC(=O)O[C@H]1\C=C\C=C\C(=O)O[C@H]2[C@@H](C)C[C@@H]3[C@]2(O)[C@H](O)[C@@]2(CO)O[C@H]2[C@H]2[C@H]4OC5(O[C@@H]([C@@H](C)[C@]32O5)[C@@]4(O)[C@](C)(O)C[C@H]2CC[C@H]1[C@H]2C)c1ccccc1 |r,t:8,10,TLB:51:32:29:39.34.35,THB:51:32:29.30.39:35,33:32:29:39.34.35,31:32:29.30.39:35| Show InChI InChI=1S/C44H58O13/c1-22(2)18-32(47)52-29-14-10-11-15-31(46)53-34-23(3)19-30-41(34,50)38(48)40(21-45)36(54-40)33-37-43(51,39(6,49)20-26-16-17-28(29)24(26)4)35-25(5)42(30,33)57-44(55-35,56-37)27-12-8-7-9-13-27/h7-15,22-26,28-30,33-38,45,48-51H,16-21H2,1-6H3/b14-10+,15-11+/t23-,24-,25+,26+,28-,29-,30+,33-,34-,35-,36-,37+,38+,39+,40-,41+,42-,43-,44?/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GCGR expressed in HEK293 cells assessed as inhibition of calcium influx after 10 mins by Fluo-4-AM based fluorimetry				J Nat Prod 75: 1058-62 (2012) Article DOI: 10.1021/np3000359 BindingDB Entry DOI: 10.7270/Q27S7PW9
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50007219 (CHEMBL3238214) Show SMILES CC(C)(C)[C@H]1CC[C@]2(CC1)N=C(C(=O)N2[C@H](CCC(F)(F)F)c1ccc(cc1)C(=O)NCc1nn[nH]n1)c1cc(Cl)cc(Cl)c1 |r,wU:4.3,15.17,wD:7.6,c:11,(50.24,-37.05,;51.42,-38.04,;49.98,-38.57,;51.16,-39.56,;52.86,-37.5,;53.12,-35.99,;54.57,-35.46,;55.76,-36.44,;55.5,-37.96,;54.05,-38.49,;56.17,-34.96,;57.72,-34.9,;58.25,-36.35,;59.73,-36.77,;57.04,-37.3,;57.09,-38.84,;55.77,-39.62,;55.79,-41.16,;54.46,-41.95,;54.48,-43.49,;53.12,-41.19,;53.12,-42.7,;58.42,-39.62,;58.4,-41.17,;59.72,-41.95,;61.07,-41.2,;61.09,-39.66,;59.76,-38.88,;62.39,-41.99,;62.37,-43.53,;63.73,-41.24,;65.05,-42.02,;66.4,-41.27,;67.79,-41.9,;68.84,-40.77,;68.08,-39.43,;66.57,-39.73,;58.49,-33.57,;57.73,-32.24,;58.51,-30.91,;57.74,-29.57,;60.05,-30.91,;60.81,-32.25,;62.35,-32.26,;60.04,-33.59,)| Show InChI InChI=1S/C31H34Cl2F3N7O2/c1-29(2,3)21-8-11-30(12-9-21)38-26(20-14-22(32)16-23(33)15-20)28(45)43(30)24(10-13-31(34,35)36)18-4-6-19(7-5-18)27(44)37-17-25-39-41-42-40-25/h4-7,14-16,21,24H,8-13,17H2,1-3H3,(H,37,44)(H,39,40,41,42)/t21-,24-,30-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from recombinant human GCGR expressed in CHO cells after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50119557 (CHEMBL3617575) Show SMILES Cc1cc(Cl)ccc1-c1ccc(NCc2cc(Cl)cc(c2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)cc1 Show InChI InChI=1S/C30H24Cl2F3N3O3/c1-17-12-21(31)5-8-24(17)18-2-6-23(7-3-18)37-16-20-13-22(32)14-25(30(33,34)35)28(20)19-4-9-26(38-15-19)29(41)36-11-10-27(39)40/h2-9,12-15,37H,10-11,16H2,1H3,(H,36,41)(H,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human glucagon receptor expressed in HEK293 cell membranes assessed as inhibition of glucagon-stimulated intracellular cAMP fo...				Bioorg Med Chem Lett 25: 4057-64 (2015) Article DOI: 10.1016/j.bmcl.2015.07.092 BindingDB Entry DOI: 10.7270/Q2HM5B7N
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075787 (4-[3-(4-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...) Show SMILES CCCOc1cc(Br)ccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H20BrClN2O/c1-2-13-29-23-14-18(25)5-8-20(23)21-15-22(16-3-6-19(26)7-4-16)28-24(21)17-9-11-27-12-10-17/h3-12,14-15,28H,2,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50358346 (CHEMBL1922696) Show SMILES Cn1c2cc(Cl)c(Cl)cc2n(Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c1=Nc1ccc(OC(F)(F)F)cc1 |w:27.31| Show InChI InChI=1S/C24H17Cl2F3N8O2/c1-36-19-10-17(25)18(26)11-20(19)37(23(36)30-15-6-8-16(9-7-15)39-24(27,28)29)12-13-2-4-14(5-3-13)21(38)31-22-32-34-35-33-22/h2-11H,12H2,1H3,(H2,31,32,33,34,35,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting				Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120370 (CHEMBL3616697) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(C)s1 Show InChI InChI=1S/C35H34F3N3O4S/c1-4-5-6-28(22-8-10-23(11-9-22)34(44)39-18-17-32(42)43)41-29-19-24(31-16-7-21(2)46-31)12-14-26(29)33(40-41)27-20-25(35(36,37)38)13-15-30(27)45-3/h7-16,19-20,28H,4-6,17-18H2,1-3H3,(H,39,44)(H,42,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120372 (CHEMBL3616699) Show SMILES COc1ccc(cc1-c1nn(C(C(C)C)c2ccc(cc2)C(=O)NCCC(O)=O)c2cc(ccc12)-c1ccc(C)cc1)C(F)(F)F Show InChI InChI=1S/C36H34F3N3O4/c1-21(2)34(24-9-11-25(12-10-24)35(45)40-18-17-32(43)44)42-30-19-26(23-7-5-22(3)6-8-23)13-15-28(30)33(41-42)29-20-27(36(37,38)39)14-16-31(29)46-4/h5-16,19-21,34H,17-18H2,1-4H3,(H,40,45)(H,43,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120373 (CHEMBL3616700) Show SMILES CCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(C)cc1 Show InChI InChI=1S/C35H32F3N3O4/c1-4-29(23-9-11-24(12-10-23)34(44)39-18-17-32(42)43)41-30-19-25(22-7-5-21(2)6-8-22)13-15-27(30)33(40-41)28-20-26(35(36,37)38)14-16-31(28)45-3/h5-16,19-20,29H,4,17-18H2,1-3H3,(H,39,44)(H,42,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50244235 (CHEMBL480692 | trans-4-(((4-tert-butylcyclohexyl)(...) Show SMILES CCCOc1ccc2n(C)c(nc2c1)N(Cc1ccc(cc1)C(=O)Nc1nnn[nH]1)[C@H]1CC[C@@H](CC1)C(C)(C)C |r,wU:30.33,wD:33.40,(15,-40.17,;14.2,-41.49,;14.94,-42.84,;14.14,-44.16,;14.88,-45.51,;14.07,-46.83,;14.81,-48.17,;16.34,-48.21,;17.35,-49.38,;16.57,-50.71,;18.77,-48.79,;18.65,-47.25,;17.15,-46.9,;16.41,-45.55,;20.1,-49.57,;20.09,-51.11,;21.42,-51.88,;22.75,-51.12,;24.08,-51.89,;24.07,-53.43,;22.73,-54.2,;21.4,-53.42,;25.4,-54.21,;25.39,-55.75,;26.74,-53.45,;28.07,-54.23,;28.59,-55.68,;30.13,-55.64,;30.57,-54.16,;29.3,-53.29,;21.43,-48.8,;21.43,-47.27,;22.78,-46.51,;24.11,-47.29,;24.09,-48.83,;22.76,-49.58,;25.45,-46.53,;26.77,-45.75,;26.22,-47.86,;24.68,-45.19,)| Show InChI InChI=1S/C30H40N8O2/c1-6-17-40-24-15-16-26-25(18-24)31-29(37(26)5)38(23-13-11-22(12-14-23)30(2,3)4)19-20-7-9-21(10-8-20)27(39)32-28-33-35-36-34-28/h7-10,15-16,18,22-23H,6,11-14,17,19H2,1-5H3,(H2,32,33,34,35,36,39)/t22-,23-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human GCGR expressed in CHO cells assessed as glucagon-induced cAMP accumulation				Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50244264 (CHEMBL471979 | trans-4-(((4-tert-butylcyclohexyl)(...) Show SMILES COc1ccc2nc(N(Cc3ccc(cc3)C(=O)Nc3nnn[nH]3)[C@H]3CC[C@@H](CC3)C(C)(C)C)n(C)c2c1 |r,wU:24.25,wD:27.32,(11.41,-44.22,;12.15,-45.57,;13.69,-45.6,;14.49,-44.28,;16.03,-44.32,;16.76,-45.67,;18.26,-46.03,;18.38,-47.56,;19.72,-48.34,;19.71,-49.88,;21.04,-50.66,;22.37,-49.89,;23.7,-50.67,;23.69,-52.21,;22.34,-52.97,;21.02,-52.19,;25.02,-52.99,;25.01,-54.53,;26.36,-52.23,;27.69,-53.01,;28.2,-54.45,;29.74,-54.42,;30.18,-52.94,;28.91,-52.07,;21.04,-47.58,;21.05,-46.04,;22.39,-45.28,;23.72,-46.06,;23.71,-47.61,;22.37,-48.36,;25.06,-45.31,;26.39,-44.53,;25.84,-46.64,;24.3,-43.97,;16.96,-48.16,;16.19,-49.49,;15.96,-46.98,;14.43,-46.95,)| Show InChI InChI=1S/C28H36N8O2/c1-28(2,3)20-10-12-21(13-11-20)36(27-29-23-15-14-22(38-5)16-24(23)35(27)4)17-18-6-8-19(9-7-18)25(37)30-26-31-33-34-32-26/h6-9,14-16,20-21H,10-13,17H2,1-5H3,(H2,30,31,32,33,34,37)/t20-,21-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells				Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50244233 (CHEMBL513067 | trans-4-(((4-tert-butylcyclohexyl)(...) Show SMILES COc1ccc2n(C)c(nc2c1)N(Cc1ccc(cc1)C(=O)Nc1nnn[nH]1)[C@H]1CC[C@@H](CC1)C(C)(C)C |r,wU:28.31,wD:31.38,(13.19,-24.98,;12.38,-26.29,;13.12,-27.64,;12.32,-28.96,;13.06,-30.31,;14.59,-30.34,;15.59,-31.52,;14.82,-32.85,;17.02,-30.92,;16.89,-29.39,;15.39,-29.03,;14.66,-27.68,;18.35,-31.7,;18.34,-33.24,;19.67,-34.02,;21,-33.25,;22.33,-34.03,;22.32,-35.57,;20.97,-36.33,;19.65,-35.55,;23.65,-36.35,;23.64,-37.89,;24.99,-35.59,;26.32,-36.37,;26.83,-37.81,;28.37,-37.78,;28.81,-36.3,;27.55,-35.43,;19.68,-30.94,;19.68,-29.4,;21.03,-28.64,;22.36,-29.42,;22.34,-30.96,;21.01,-31.72,;23.7,-28.67,;25.02,-27.89,;24.47,-30,;22.93,-27.33,)| Show InChI InChI=1S/C28H36N8O2/c1-28(2,3)20-10-12-21(13-11-20)36(27-29-23-16-22(38-5)14-15-24(23)35(27)4)17-18-6-8-19(9-7-18)25(37)30-26-31-33-34-32-26/h6-9,14-16,20-21H,10-13,17H2,1-5H3,(H2,30,31,32,33,34,37)/t20-,21-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells				Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50244122 (CHEMBL459457 | trans-4-(((4-tert-butylcyclohexyl)(...) Show SMILES Cn1c(nc2ccccc12)N(Cc1ccc(cc1)C(=O)Nc1nnn[nH]1)[C@H]1CC[C@@H](CC1)C(C)(C)C |r,wU:26.29,wD:29.36,(21.92,-38.87,;22.27,-37.38,;23.7,-36.78,;23.58,-35.25,;22.08,-34.89,;21.34,-33.54,;19.8,-33.5,;19,-34.82,;19.74,-36.17,;21.27,-36.2,;25.03,-37.56,;25.02,-39.1,;26.35,-39.88,;27.68,-39.11,;29.01,-39.89,;29,-41.43,;27.66,-42.19,;26.33,-41.41,;30.33,-42.21,;30.32,-43.75,;31.67,-41.45,;33,-42.22,;33.52,-43.67,;35.06,-43.64,;35.5,-42.16,;34.23,-41.29,;26.36,-36.8,;26.36,-35.26,;27.71,-34.5,;29.04,-35.28,;29.02,-36.82,;27.69,-37.58,;30.38,-34.53,;31.7,-33.74,;31.15,-35.86,;29.61,-33.19,)| Show InChI InChI=1S/C27H34N8O/c1-27(2,3)20-13-15-21(16-14-20)35(26-28-22-7-5-6-8-23(22)34(26)4)17-18-9-11-19(12-10-18)24(36)29-25-30-32-33-31-25/h5-12,20-21H,13-17H2,1-4H3,(H2,29,30,31,32,33,36)/t20-,21-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells				Bioorg Med Chem Lett 18: 3701-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.072 BindingDB Entry DOI: 10.7270/Q26Q1X25
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50245098 ((R)-3-{4-[1-(4-Cyclohexylphenyl)-3-(3,5-dichloroph...) Show SMILES O[C@H](CNC(=O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(cc2)C2CCCCC2)cc1)C(O)=O |r| Show InChI InChI=1S/C30H31Cl2N3O5/c31-23-14-24(32)16-25(15-23)34-30(40)35(26-12-10-21(11-13-26)20-4-2-1-3-5-20)18-19-6-8-22(9-7-19)28(37)33-17-27(36)29(38)39/h6-16,20,27,36H,1-5,17-18H2,(H,33,37)(H,34,40)(H,38,39)/t27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to human cloned GluR expressed in BHK cells				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120212 (CHEMBL3616581) Show SMILES CCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)cc1 Show InChI InChI=1S/C36H34F3N3O5/c1-4-5-30(23-6-8-24(9-7-23)35(45)40-19-18-33(43)44)42-31-20-25(22-10-14-27(46-2)15-11-22)12-16-28(31)34(41-42)29-21-26(36(37,38)39)13-17-32(29)47-3/h6-17,20-21,30H,4-5,18-19H2,1-3H3,(H,40,45)(H,43,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120318 (CHEMBL3616587) Show SMILES CCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1cc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(C)cc1 Show InChI InChI=1S/C37H35F3N2O4/c1-4-5-32(25-10-12-26(13-11-25)36(45)41-19-18-35(43)44)42-22-31(30-21-28(37(38,39)40)15-17-34(30)46-3)29-16-14-27(20-33(29)42)24-8-6-23(2)7-9-24/h6-17,20-22,32H,4-5,18-19H2,1-3H3,(H,41,45)(H,43,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120323 (CHEMBL3616592) Show SMILES COc1cc(F)c(F)cc1-c1nn(C(C)c2ccc(cc2)C(=O)NCCC(O)=O)c2cc(ccc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C33H26F5N3O5/c1-18(19-3-5-21(6-4-19)32(44)39-14-13-30(42)43)41-28-15-22(20-7-10-23(11-8-20)46-33(36,37)38)9-12-24(28)31(40-41)25-16-26(34)27(35)17-29(25)45-2/h3-12,15-18H,13-14H2,1-2H3,(H,39,44)(H,42,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120334 (CHEMBL3616682) Show SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2ccc(Cl)c(F)c2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C32H24ClF4N3O4/c1-18(19-2-4-21(5-3-19)31(43)38-15-14-29(41)42)40-28-17-22(20-6-10-24(11-7-20)44-32(35,36)37)8-12-25(28)30(39-40)23-9-13-26(33)27(34)16-23/h2-13,16-18H,14-15H2,1H3,(H,38,43)(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120363 (CHEMBL3616691) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)cc1Cl Show InChI InChI=1S/C37H35ClF3N3O5/c1-4-5-6-31(22-7-9-23(10-8-22)36(47)42-18-17-34(45)46)44-32-19-24(27-15-13-26(48-2)21-30(27)38)11-14-28(32)35(43-44)29-20-25(37(39,40)41)12-16-33(29)49-3/h7-16,19-21,31H,4-6,17-18H2,1-3H3,(H,42,47)(H,45,46)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50393780 (CHEMBL2159353) Show SMILES COc1ccc2cc(ccc2c1)-c1cc(nn1[C@@H](C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(ccc1F)C(F)(F)F |r| Show InChI InChI=1S/C33H27F4N3O4/c1-19(20-3-5-21(6-4-20)32(43)38-14-13-31(41)42)40-30(24-8-7-23-16-26(44-2)11-9-22(23)15-24)18-29(39-40)27-17-25(33(35,36)37)10-12-28(27)34/h3-12,15-19H,13-14H2,1-2H3,(H,38,43)(H,41,42)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay				J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50199498 (3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(4-(tri...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1 |w:11.11,wU:7.10,wD:4.3,(-2.01,-7.56,;-2,-6.03,;-.46,-6.04,;-3.54,-6.03,;-2,-4.49,;-.66,-3.72,;-.65,-2.17,;-1.98,-1.41,;-3.33,-2.18,;-3.33,-3.71,;-1.98,.13,;-.64,.9,;-.33,2.4,;1.53,2.36,;2.01,.91,;3.34,.15,;3.35,-1.4,;2.01,-2.17,;.68,-1.41,;.69,.13,;4.68,-2.17,;4.69,-3.71,;6.02,-1.4,;7.35,-2.16,;8.68,-1.39,;10.02,-2.16,;11.35,-1.39,;10.02,-3.7,;-3.31,.9,;-3.32,2.44,;-4.65,.13,;-5.98,.89,;-7.32,.12,;-8.65,.89,;-8.65,2.44,;-9.99,3.21,;-9.99,4.75,;-10,6.29,;-8.45,4.75,;-11.53,4.74,;-7.33,3.21,;-5.99,2.45,)| Show InChI InChI=1S/C31H38F3N3O5/c1-30(2,3)21-6-10-23(11-7-21)37(29(41)36-22-8-12-24(13-9-22)42-31(32,33)34)26-15-5-19-18-20(4-14-25(19)26)28(40)35-17-16-27(38)39/h4,8-9,12-14,18,21,23,26H,5-7,10-11,15-17H2,1-3H3,(H,35,40)(H,36,41)(H,38,39)/t21-,23-,26?	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50199498 (3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(4-(tri...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1 |w:11.11,wU:7.10,wD:4.3,(-2.01,-7.56,;-2,-6.03,;-.46,-6.04,;-3.54,-6.03,;-2,-4.49,;-.66,-3.72,;-.65,-2.17,;-1.98,-1.41,;-3.33,-2.18,;-3.33,-3.71,;-1.98,.13,;-.64,.9,;-.33,2.4,;1.53,2.36,;2.01,.91,;3.34,.15,;3.35,-1.4,;2.01,-2.17,;.68,-1.41,;.69,.13,;4.68,-2.17,;4.69,-3.71,;6.02,-1.4,;7.35,-2.16,;8.68,-1.39,;10.02,-2.16,;11.35,-1.39,;10.02,-3.7,;-3.31,.9,;-3.32,2.44,;-4.65,.13,;-5.98,.89,;-7.32,.12,;-8.65,.89,;-8.65,2.44,;-9.99,3.21,;-9.99,4.75,;-10,6.29,;-8.45,4.75,;-11.53,4.74,;-7.33,3.21,;-5.99,2.45,)| Show InChI InChI=1S/C31H38F3N3O5/c1-30(2,3)21-6-10-23(11-7-21)37(29(41)36-22-8-12-24(13-9-22)42-31(32,33)34)26-15-5-19-18-20(4-14-25(19)26)28(40)35-17-16-27(38)39/h4,8-9,12-14,18,21,23,26H,5-7,10-11,15-17H2,1-3H3,(H,35,40)(H,36,41)(H,38,39)/t21-,23-,26?	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50393786 (CHEMBL2159342) Show SMILES CC(C)c1ccc2cc(ccc2c1)-c1cc(nn1[C@@H](C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C34H31Cl2N3O3/c1-20(2)24-8-9-26-15-27(11-10-25(26)14-24)32-19-31(28-16-29(35)18-30(36)17-28)38-39(32)21(3)22-4-6-23(7-5-22)34(42)37-13-12-33(40)41/h4-11,14-21H,12-13H2,1-3H3,(H,37,42)(H,40,41)/t21-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay				J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50110074 (3-Chloro-4-hydroxy-benzoic acid [1-[4-(4-isopropyl...) Show SMILES CC(C)c1ccc(COc2ccc(\C=N\NC(=O)c3ccc(O)c(Cl)c3)c3ccccc23)cc1 Show InChI InChI=1S/C28H25ClN2O3/c1-18(2)20-9-7-19(8-10-20)17-34-27-14-12-22(23-5-3-4-6-24(23)27)16-30-31-28(33)21-11-13-26(32)25(29)15-21/h3-16,18,32H,17H2,1-2H3,(H,31,33)/b30-16+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cells				J Med Chem 45: 5755-75 (2002) BindingDB Entry DOI: 10.7270/Q26W99FD
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50358362 (CHEMBL1922710) Show SMILES CCc1cc(cc2n(Cc3ccc(cc3)C(=O)Nc3nnn[nH]3)c(=Nc3ccc(cc3)C(C)(C)C)n(C)c12)C(F)(F)F |w:24.26| Show InChI InChI=1S/C30H31F3N8O/c1-6-19-15-22(30(31,32)33)16-24-25(19)40(5)28(34-23-13-11-21(12-14-23)29(2,3)4)41(24)17-18-7-9-20(10-8-18)26(42)35-27-36-38-39-37-27/h7-16H,6,17H2,1-5H3,(H2,35,36,37,38,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting				Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50122116 (3-Chloro-4-hydroxy-benzoic acid (4-{2-[4-(4-chloro...) Show SMILES Oc1ccc(cc1Cl)C(=O)N\N=C\c1ccc(CC(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C31H28Cl2N4O3/c32-25-10-5-21(6-11-25)20-36-13-15-37(16-14-36)30(39)18-22-7-8-24(27-4-2-1-3-26(22)27)19-34-35-31(40)23-9-12-29(38)28(33)17-23/h1-12,17,19,38H,13-16,18,20H2,(H,35,40)/b34-19+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cells				J Med Chem 45: 5755-75 (2002) BindingDB Entry DOI: 10.7270/Q26W99FD
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50393785 (CHEMBL2159341) Show SMILES C[C@@H](c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(cc1-c1ccc2cc(C)ccc2c1)-c1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C32H27Cl2N3O3/c1-19-3-4-24-14-25(10-9-23(24)13-19)30-18-29(26-15-27(33)17-28(34)16-26)36-37(30)20(2)21-5-7-22(8-6-21)32(40)35-12-11-31(38)39/h3-10,13-18,20H,11-12H2,1-2H3,(H,35,40)(H,38,39)/t20-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay				J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM235125 (US9359339, 2) Show SMILES CCCC[C@@H](C(c1csc2c(cc(F)cc12)-c1ccnn1C)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C34H33ClFN3O3S/c1-3-4-5-26(21-6-8-23(9-7-21)34(42)37-16-15-31(40)41)32(22-10-12-24(35)13-11-22)29-20-43-33-27(29)18-25(36)19-28(33)30-14-17-38-39(30)2/h6-14,17-20,26,32H,3-5,15-16H2,1-2H3,(H,37,42)(H,40,41)/t26-,32?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	7.5	25
Merck Sharp & Dohme Corp. US Patent					Assay Description A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...				US Patent US9359339 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VHC
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50199493 (1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(triflu...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)Nc1nnn[nH]1)C(=O)Cc1ccc(OC(F)(F)F)cc1 |w:11.11,wU:7.10,wD:4.3,(23.62,-41.57,;23.63,-40.04,;25.17,-40.04,;22.09,-40.03,;23.64,-38.5,;24.97,-37.73,;24.98,-36.18,;23.65,-35.42,;22.31,-36.19,;22.3,-37.72,;23.65,-33.88,;24.99,-33.11,;25.31,-31.61,;27.17,-31.64,;27.64,-33.1,;28.97,-33.86,;28.98,-35.41,;27.65,-36.18,;26.31,-35.41,;26.32,-33.88,;30.32,-36.18,;30.32,-37.72,;31.65,-35.41,;32.98,-36.17,;33.15,-37.7,;34.65,-38.02,;35.42,-36.68,;34.39,-35.54,;22.32,-33.11,;22.32,-31.57,;20.99,-33.88,;19.65,-33.11,;18.31,-33.89,;16.98,-33.11,;16.98,-31.57,;15.65,-30.8,;15.64,-29.26,;15.63,-27.72,;17.18,-29.25,;14.1,-29.27,;18.3,-30.8,;19.64,-31.56,)| Show InChI InChI=1S/C30H35F3N6O3/c1-29(2,3)21-8-10-22(11-9-21)39(26(40)16-18-4-12-23(13-5-18)42-30(31,32)33)25-15-7-19-17-20(6-14-24(19)25)27(41)34-28-35-37-38-36-28/h4-6,12-14,17,21-22,25H,7-11,15-16H2,1-3H3,(H2,34,35,36,37,38,41)/t21-,22-,25?	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50199495 (1-(5-((2H-tetrazol-5-yl)carbamoyl)-2,3-dihydro-1H-...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)Nc1nnn[nH]1)C(=O)Nc1cc(Cl)cc(Cl)c1 |w:11.11,wU:7.10,wD:4.3,(23.03,-6.29,;23.04,-4.75,;24.58,-4.76,;21.5,-4.75,;23.05,-3.21,;24.38,-2.44,;24.39,-.9,;23.06,-.14,;21.72,-.9,;21.71,-2.44,;23.06,1.4,;24.4,2.17,;24.72,3.67,;26.58,3.64,;27.05,2.18,;28.38,1.42,;28.39,-.13,;27.06,-.9,;25.72,-.13,;25.73,1.41,;29.73,-.9,;29.73,-2.44,;31.06,-.12,;32.39,-.89,;32.56,-2.42,;34.06,-2.74,;34.83,-1.4,;33.8,-.26,;21.73,2.17,;21.73,3.71,;20.4,1.4,;19.06,2.17,;19.05,3.72,;17.71,4.48,;17.71,6.02,;16.39,3.71,;16.39,2.17,;15.05,1.4,;17.72,1.4,)| Show InChI InChI=1S/C28H33Cl2N7O2/c1-28(2,3)18-6-8-22(9-7-18)37(27(39)31-21-14-19(29)13-20(30)15-21)24-11-5-16-12-17(4-10-23(16)24)25(38)32-26-33-35-36-34-26/h4,10,12-15,18,22,24H,5-9,11H2,1-3H3,(H,31,39)(H2,32,33,34,35,36,38)/t18-,22-,24?	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125]glucagon from human glucagon receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50122160 (3-Cyano-4-hydroxy-benzoic acid {4-[4-(4-chloro-ben...) Show SMILES Oc1ccc(cc1C#N)C(=O)N\N=C\c1ccc(C(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C31H26ClN5O3/c32-25-9-5-21(6-10-25)20-36-13-15-37(16-14-36)31(40)28-11-7-23(26-3-1-2-4-27(26)28)19-34-35-30(39)22-8-12-29(38)24(17-22)18-33/h1-12,17,19,38H,13-16,20H2,(H,35,39)/b34-19+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cells				J Med Chem 45: 5755-75 (2002) BindingDB Entry DOI: 10.7270/Q26W99FD
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120281 (CHEMBL3616584) Show SMILES CCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(C)cc1 Show InChI InChI=1S/C36H34F3N3O4/c1-4-5-30(24-10-12-25(13-11-24)35(45)40-19-18-33(43)44)42-31-20-26(23-8-6-22(2)7-9-23)14-16-28(31)34(41-42)29-21-27(36(37,38)39)15-17-32(29)46-3/h6-17,20-21,30H,4-5,18-19H2,1-3H3,(H,40,45)(H,43,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120324 (CHEMBL3616672) Show SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2F)C(F)(F)F)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C33H24F7N3O4/c1-18(19-2-4-21(5-3-19)31(46)41-15-14-29(44)45)43-28-16-22(20-6-10-24(11-7-20)47-33(38,39)40)8-12-25(28)30(42-43)26-17-23(32(35,36)37)9-13-27(26)34/h2-13,16-18H,14-15H2,1H3,(H,41,46)(H,44,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50245102 ((R)-3-{4-[1-(4-Cyclohex-1-enylphenyl)-3-(3-methane...) Show SMILES CS(=O)(=O)c1cc(NC(=O)N(Cc2ccc(cc2)C(=O)NC[C@@H](O)C(O)=O)c2ccc(cc2)C2=CCCCC2)ccc1OC(F)(F)F |r,t:35| Show InChI InChI=1S/C32H32F3N3O8S/c1-47(44,45)28-17-24(13-16-27(28)46-32(33,34)35)37-31(43)38(25-14-11-22(12-15-25)21-5-3-2-4-6-21)19-20-7-9-23(10-8-20)29(40)36-18-26(39)30(41)42/h5,7-17,26,39H,2-4,6,18-19H2,1H3,(H,36,40)(H,37,43)(H,41,42)/t26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to human cloned GluR expressed in BHK cells				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50393775 (CHEMBL2159348) Show SMILES COc1ccc2cc(ccc2c1)-c1cc(nn1[C@@H](C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C32H27Cl2N3O4/c1-19(20-3-5-21(6-4-20)32(40)35-14-13-31(38)39)37-30(18-29(36-37)24-10-12-27(33)28(34)17-24)25-8-7-23-16-26(41-2)11-9-22(23)15-25/h3-12,15-19H,13-14H2,1-2H3,(H,35,40)(H,38,39)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assay				J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50071873 (4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...) Show SMILES CS(=O)c1ccc(cc1)-c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C22H17FN2OS/c1-27(26)19-8-4-16(5-9-19)21-14-20(15-10-12-24-13-11-15)22(25-21)17-2-6-18(23)7-3-17/h2-14,25H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human glucagon receptor				Citation and Details Article DOI: 10.1007/s00044-013-0801-3 BindingDB Entry DOI: 10.7270/Q20G3MM3
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50122135 (3-Chloro-4-hydroxy-benzoic acid [1-(2,3,5,6-tetram...) Show SMILES Cc1cc(C)c(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(Cl)c4)cccc23)c1C Show InChI InChI=1S/C27H26ClN3O2/c1-16-12-17(2)19(4)23(18(16)3)15-31-11-10-22-21(6-5-7-25(22)31)14-29-30-27(33)20-8-9-26(32)24(28)13-20/h5-14,32H,15H2,1-4H3,(H,30,33)/b29-14+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cells				J Med Chem 45: 5755-75 (2002) BindingDB Entry DOI: 10.7270/Q26W99FD
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120319 (CHEMBL3616588) Show SMILES CCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C36H31F6N3O5/c1-3-4-29(22-5-7-23(8-6-22)34(48)43-18-17-32(46)47)45-30-19-24(21-9-13-26(14-10-21)50-36(40,41)42)11-15-27(30)33(44-45)28-20-25(35(37,38)39)12-16-31(28)49-2/h5-16,19-20,29H,3-4,17-18H2,1-2H3,(H,43,48)(H,46,47)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50358810 (CHEMBL1922938) Show SMILES CCCCC[C@@H](Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(OC(F)(F)F)ccc2n1-c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C34H32F6N2O5/c1-2-3-4-6-23(17-21-9-11-22(12-10-21)32(46)41-16-15-30(43)44)31(45)29-19-24-18-27(47-34(38,39)40)13-14-28(24)42(29)26-8-5-7-25(20-26)33(35,36)37/h5,7-14,18-20,23H,2-4,6,15-17H2,1H3,(H,41,46)(H,43,44)/t23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from human glucagon receptor expressed in CHO cells after 4 to 12 hrs by scintillation proximity assay				Bioorg Med Chem Lett 21: 7124-30 (2011) Article DOI: 10.1016/j.bmcl.2011.09.105 BindingDB Entry DOI: 10.7270/Q2HT2PRF
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50393776 (CHEMBL2159349) Show SMILES COc1ccc2cc(ccc2c1)-c1cc(nn1[C@@H](C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(Cl)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C33H27ClF3N3O4/c1-19(20-3-5-21(6-4-20)32(43)38-12-11-31(41)42)40-30(24-8-7-23-16-28(44-2)10-9-22(23)13-24)18-29(39-40)25-14-26(33(35,36)37)17-27(34)15-25/h3-10,13-19H,11-12H2,1-2H3,(H,38,43)(H,41,42)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...				J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50122142 (3-Chloro-4-hydroxy-benzoic acid [1-(2,4,6-trimethy...) Show SMILES Cc1cc(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(Cl)c4)cccc23)c(C)c1 Show InChI InChI=1S/C26H24ClN3O2/c1-16-11-17(2)22(18(3)12-16)15-30-10-9-21-20(5-4-6-24(21)30)14-28-29-26(32)19-7-8-25(31)23(27)13-19/h4-14,31H,15H2,1-3H3,(H,29,32)/b28-14+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cells				J Med Chem 45: 5755-75 (2002) BindingDB Entry DOI: 10.7270/Q26W99FD
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50199495 (1-(5-((2H-tetrazol-5-yl)carbamoyl)-2,3-dihydro-1H-...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)Nc1nnn[nH]1)C(=O)Nc1cc(Cl)cc(Cl)c1 |w:11.11,wU:7.10,wD:4.3,(23.03,-6.29,;23.04,-4.75,;24.58,-4.76,;21.5,-4.75,;23.05,-3.21,;24.38,-2.44,;24.39,-.9,;23.06,-.14,;21.72,-.9,;21.71,-2.44,;23.06,1.4,;24.4,2.17,;24.72,3.67,;26.58,3.64,;27.05,2.18,;28.38,1.42,;28.39,-.13,;27.06,-.9,;25.72,-.13,;25.73,1.41,;29.73,-.9,;29.73,-2.44,;31.06,-.12,;32.39,-.89,;32.56,-2.42,;34.06,-2.74,;34.83,-1.4,;33.8,-.26,;21.73,2.17,;21.73,3.71,;20.4,1.4,;19.06,2.17,;19.05,3.72,;17.71,4.48,;17.71,6.02,;16.39,3.71,;16.39,2.17,;15.05,1.4,;17.72,1.4,)| Show InChI InChI=1S/C28H33Cl2N7O2/c1-28(2,3)18-6-8-22(9-7-18)37(27(39)31-21-14-19(29)13-20(30)15-21)24-11-5-16-12-17(4-10-23(16)24)25(38)32-26-33-35-36-34-26/h4,10,12-15,18,22,24H,5-9,11H2,1-3H3,(H,31,39)(H2,32,33,34,35,36,38)/t18-,22-,24?	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human glucagon receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation				Bioorg Med Chem Lett 17: 587-92 (2007) Article DOI: 10.1016/j.bmcl.2006.11.014 BindingDB Entry DOI: 10.7270/Q2N58M0Q
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50122152 (4-[(3-Chloro-4-hydroxy-benzoyl)-hydrazonomethyl]-n...) Show SMILES Oc1ccc(cc1Cl)C(=O)N\N=C\c1ccc(C(=O)NCCc2ccc(Cl)cc2)c2ccccc12 Show InChI InChI=1S/C27H21Cl2N3O3/c28-20-9-5-17(6-10-20)13-14-30-27(35)23-11-7-19(21-3-1-2-4-22(21)23)16-31-32-26(34)18-8-12-25(33)24(29)15-18/h1-12,15-16,33H,13-14H2,(H,30,35)(H,32,34)/b31-16+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cells				J Med Chem 45: 5755-75 (2002) BindingDB Entry DOI: 10.7270/Q26W99FD
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50007389 (CHEMBL3237900) Show SMILES C[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(F)cc(Cl)c1)c1ccc(cc1)C(=O)NCCC(O)=O |r,wU:10.14,1.0,wD:7.8,c:5,(20.39,-28.33,;21.71,-27.55,;21.66,-26.01,;22.87,-25.06,;24.35,-25.48,;22.34,-23.62,;20.79,-23.68,;20.38,-25.15,;19.19,-24.17,;17.74,-24.7,;17.48,-26.22,;18.67,-27.2,;20.12,-26.67,;16.04,-26.75,;14.86,-25.76,;14.6,-27.28,;15.78,-28.27,;23.11,-22.29,;24.66,-22.3,;25.43,-20.97,;26.97,-20.98,;24.67,-19.63,;23.13,-19.62,;22.36,-18.28,;22.35,-20.95,;23.04,-28.33,;23.01,-29.88,;24.34,-30.66,;25.69,-29.91,;25.71,-28.37,;24.38,-27.59,;27.01,-30.7,;26.99,-32.24,;28.35,-29.95,;29.67,-30.73,;31.02,-29.98,;32.34,-30.76,;33.68,-30,;32.32,-32.3,)| Show InChI InChI=1S/C30H35ClFN3O4/c1-18(19-5-7-20(8-6-19)27(38)33-14-11-25(36)37)35-28(39)26(21-15-23(31)17-24(32)16-21)34-30(35)12-9-22(10-13-30)29(2,3)4/h5-8,15-18,22H,9-14H2,1-4H3,(H,33,38)(H,36,37)/t18-,22-,30-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from recombinant human GCGR expressed in CHO cells after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50358374 (CHEMBL1922840) Show SMILES CCCOc1cc(cc2n(Cc3ccc(cc3)C(=O)Nc3nnn[nH]3)c(=Nc3ccc(cc3)C(F)(F)F)n(C)c12)C(F)(F)F |w:26.28| Show InChI InChI=1S/C28H24F6N8O2/c1-3-12-44-22-14-19(28(32,33)34)13-21-23(22)41(2)26(35-20-10-8-18(9-11-20)27(29,30)31)42(21)15-16-4-6-17(7-5-16)24(43)36-25-37-39-40-38-25/h4-11,13-14H,3,12,15H2,1-2H3,(H2,36,37,38,39,40,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation counting				Bioorg Med Chem Lett 21: 7131-6 (2011) Article DOI: 10.1016/j.bmcl.2011.09.085 BindingDB Entry DOI: 10.7270/Q2C829QP
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50075783 (4-[5-(4-Chloro-phenyl)-3-(5-chloro-2-propoxy-pheny...) Show SMILES CCCOc1ccc(Cl)cc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H20Cl2N2O/c1-2-13-29-23-8-7-19(26)14-20(23)21-15-22(16-3-5-18(25)6-4-16)28-24(21)17-9-11-27-12-10-17/h3-12,14-15,28H,2,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120335 (CHEMBL3616683) Show SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(F)c(F)c(F)c2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C32H23F6N3O4/c1-17(18-2-4-20(5-3-18)31(44)39-13-12-28(42)43)41-27-16-21(19-6-9-23(10-7-19)45-32(36,37)38)8-11-24(27)30(40-41)22-14-25(33)29(35)26(34)15-22/h2-11,14-17H,12-13H2,1H3,(H,39,44)(H,42,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair

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