Compile Data Set for Download or QSAR

Found 113 hits Enz. Inhib. hit(s) with all data for entry = 9725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484080 (12-ethyl-8-isopentyl-4-oxa-8,12- diazadispiro[2.1....) Show SMILES CCN1CC2(CCN(CCC(C)C)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C17H30N2O2/c1-4-19-13-16(21-17(6-7-17)15(19)20)8-11-18(12-9-16)10-5-14(2)3/h14H,4-13H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484168 ((S)-9-(4-fluorobenzyl)-2,4- dimethyl-1-oxa-4,9- di...) Show SMILES C[C@@H]1OC2(CCN(Cc3ccc(F)cc3)CC2)CN(C)C1=O |r| Show InChI InChI=1S/C17H23FN2O2/c1-13-16(21)19(2)12-17(22-13)7-9-20(10-8-17)11-14-3-5-15(18)6-4-14/h3-6,13H,7-12H2,1-2H3/t13-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484084 (8-isopentyl-12-isopropyl-4-oxa-8,12- diazadispiro[...) Show SMILES CC(C)CCN1CCC2(CC1)CN(C(C)C)C(=O)C1(CC1)O2 Show InChI InChI=1S/C18H32N2O2/c1-14(2)5-10-19-11-8-17(9-12-19)13-20(15(3)4)16(21)18(22-17)6-7-18/h14-15H,5-13H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484086 ((S)-4-ethyl-9-isopentyl-2-methyl-1-oxa- 4,9-diazas...) Show SMILES CCN1CC2(CCN(CCC(C)C)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C16H30N2O2/c1-5-18-12-16(20-14(4)15(18)19)7-10-17(11-8-16)9-6-13(2)3/h13-14H,5-12H2,1-4H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484088 (8-isopentyl-12-propyl-4-oxa-8,12- diazadispiro[2.1...) Show SMILES CCCN1CC2(CCN(CCC(C)C)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C18H32N2O2/c1-4-10-20-14-17(22-18(6-7-18)16(20)21)8-12-19(13-9-17)11-5-15(2)3/h15H,4-14H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484089 (12-isobutyl-8-isopentyl-4-oxa-8,12- diazadispiro[2...) Show SMILES CC(C)CCN1CCC2(CC1)CN(CC(C)C)C(=O)C1(CC1)O2 Show InChI InChI=1S/C19H34N2O2/c1-15(2)5-10-20-11-8-18(9-12-20)14-21(13-16(3)4)17(22)19(23-18)6-7-19/h15-16H,5-14H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484094 (4-ethyl-9-isopentyl-2,2-dimethyl-1-oxa- 4,9-diazas...) Show SMILES CCN1CC2(CCN(CCC(C)C)CC2)OC(C)(C)C1=O Show InChI InChI=1S/C17H32N2O2/c1-6-19-13-17(21-16(4,5)15(19)20)8-11-18(12-9-17)10-7-14(2)3/h14H,6-13H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484095 (12-ethyl-8-(4-fluorobenzyl)-4-oxa-8,12- diazadispi...) Show SMILES CCN1CC2(CCN(Cc3ccc(F)cc3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C19H25FN2O2/c1-2-22-14-18(24-19(7-8-19)17(22)23)9-11-21(12-10-18)13-15-3-5-16(20)6-4-15/h3-6H,2,7-14H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484096 (8-benzyl-12-ethyl-4-oxa-8,12- diazadispiro[2.1.5.3...) Show SMILES CCN1CC2(CCN(Cc3ccccc3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C19H26N2O2/c1-2-21-15-18(23-19(8-9-19)17(21)22)10-12-20(13-11-18)14-16-6-4-3-5-7-16/h3-7H,2,8-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484097 (8-benzyl-12-methyl-4-oxa-8,12- diazadispiro[2.1.5....) Show SMILES CN1CC2(CCN(Cc3ccccc3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C18H24N2O2/c1-19-14-17(22-18(7-8-18)16(19)21)9-11-20(12-10-17)13-15-5-3-2-4-6-15/h2-6H,7-14H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484098 ((R)-9-benzyl-4-ethyl-2-methyl-1-oxa- 4,9-diazaspir...) Show SMILES CCN1CC2(CCN(Cc3ccccc3)CC2)O[C@H](C)C1=O |r| Show InChI InChI=1S/C18H26N2O2/c1-3-20-14-18(22-15(2)17(20)21)9-11-19(12-10-18)13-16-7-5-4-6-8-16/h4-8,15H,3,9-14H2,1-2H3/t15-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484099 (8-benzyl-12-isopropyl-4-oxa-8,12- diazadispiro[2.1...) Show SMILES CC(C)N1CC2(CCN(Cc3ccccc3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C20H28N2O2/c1-16(2)22-15-19(24-20(8-9-20)18(22)23)10-12-21(13-11-19)14-17-6-4-3-5-7-17/h3-7,16H,8-15H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484101 ((S)-9-benzyl-4-ethyl-2-methyl-1-oxa- 4,9-diazaspir...) Show SMILES CCN1CC2(CCN(Cc3ccccc3)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C18H26N2O2/c1-3-20-14-18(22-15(2)17(20)21)9-11-19(12-10-18)13-16-7-5-4-6-8-16/h4-8,15H,3,9-14H2,1-2H3/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484102 (12-ethyl-8-(3-fluorobenzyl)-4-oxa-8,12- diazadispi...) Show SMILES CCN1CC2(CCN(Cc3cccc(F)c3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C19H25FN2O2/c1-2-22-14-18(24-19(6-7-19)17(22)23)8-10-21(11-9-18)13-15-4-3-5-16(20)12-15/h3-5,12H,2,6-11,13-14H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484103 (8-(3,4-difluorobenzyl)-12-ethyl-4-oxa-8,12- diazad...) Show SMILES CCN1CC2(CCN(Cc3ccc(F)c(F)c3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C19H24F2N2O2/c1-2-23-13-18(25-19(5-6-19)17(23)24)7-9-22(10-8-18)12-14-3-4-15(20)16(21)11-14/h3-4,11H,2,5-10,12-13H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484105 (8-benzyl-12-propyl-4-oxa-8,12- diazadispiro[2.1.5....) Show SMILES CCCN1CC2(CCN(Cc3ccccc3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C20H28N2O2/c1-2-12-22-16-19(24-20(8-9-20)18(22)23)10-13-21(14-11-19)15-17-6-4-3-5-7-17/h3-7H,2,8-16H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484106 (8-benzyl-12-isobutyl-4-oxa-8,12- diazadispiro[2.1....) Show SMILES CC(C)CN1CC2(CCN(Cc3ccccc3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C21H30N2O2/c1-17(2)14-23-16-20(25-21(8-9-21)19(23)24)10-12-22(13-11-20)15-18-6-4-3-5-7-18/h3-7,17H,8-16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484111 (9-benzyl-4-ethyl-2,2-dimethyl-1-oxa- 4,9-diazaspir...) Show SMILES CCN1CC2(CCN(Cc3ccccc3)CC2)OC(C)(C)C1=O Show InChI InChI=1S/C19H28N2O2/c1-4-21-15-19(23-18(2,3)17(21)22)10-12-20(13-11-19)14-16-8-6-5-7-9-16/h5-9H,4,10-15H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484115 (8-(2-(3-fluoropyridin-2-yl)ethyl)-12-isopropyl-4- ...) Show SMILES CC(C)N1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1 Show InChI InChI=1S/C20H30FN3O/c1-16(2)24-14-19(6-7-19)25-20(15-24)8-12-23(13-9-20)11-5-18-17(21)4-3-10-22-18/h3-4,10,16H,5-9,11-15H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484117 ((S)-9-(2-(3-fluoropyridin-2-yl)ethyl-4-isopropyl- ...) Show SMILES CC(C)N1C[C@H](C)OC2(CCN(CCc3ncccc3F)CC2)C1 |r| Show InChI InChI=1S/C19H30FN3O/c1-15(2)23-13-16(3)24-19(14-23)7-11-22(12-8-19)10-6-18-17(20)5-4-9-21-18/h4-5,9,15-16H,6-8,10-14H2,1-3H3/t16-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484119 (8-(2-(3-fluoropyridin-2-yl)ethyl)-12-propyl-4- oxa...) Show SMILES CCCN1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1 Show InChI InChI=1S/C20H30FN3O/c1-2-11-24-15-19(6-7-19)25-20(16-24)8-13-23(14-9-20)12-5-18-17(21)4-3-10-22-18/h3-4,10H,2,5-9,11-16H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484121 (8-(2-(3-fluoropyridin-2-yl)ethyl)-12-isobutyl-4- o...) Show SMILES CC(C)CN1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1 Show InChI InChI=1S/C21H32FN3O/c1-17(2)14-25-15-20(6-7-20)26-21(16-25)8-12-24(13-9-21)11-5-19-18(22)4-3-10-23-19/h3-4,10,17H,5-9,11-16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484124 (9-isopentyl-4-isopropyl-2,2- dimethyl-1-oxa-4,9- d...) Show SMILES CC(C)CCN1CCC2(CC1)CN(C(C)C)C(=O)C(C)(C)O2 Show InChI InChI=1S/C18H34N2O2/c1-14(2)7-10-19-11-8-18(9-12-19)13-20(15(3)4)16(21)17(5,6)22-18/h14-15H,7-13H2,1-6H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484125 (8-(2,5-difluorophenethyl)-12- isobutyl-4-oxa-8,12-...) Show SMILES CC(C)CN1CC2(CC2)OC2(CCN(CCc3cc(F)ccc3F)CC2)C1 Show InChI InChI=1S/C22H32F2N2O/c1-17(2)14-26-15-21(6-7-21)27-22(16-26)8-11-25(12-9-22)10-5-18-13-19(23)3-4-20(18)24/h3-4,13,17H,5-12,14-16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484126 (12-isobutyl-8-(2-(6- methoxypyridin-2-yl)ethyl)-4-...) Show SMILES COc1cccc(CCN2CCC3(CC2)CN(CC(C)C)CC2(CC2)O3)n1 Show InChI InChI=1S/C22H35N3O2/c1-18(2)15-25-16-21(8-9-21)27-22(17-25)10-13-24(14-11-22)12-7-19-5-4-6-20(23-19)26-3/h4-6,18H,7-17H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484127 (9-(3,3-dimethylbutyl)-4- propyl-1-oxa-4,9- diazasp...) Show SMILES CCCN1CC2(CCN(CCC(C)(C)C)CC2)OCC1=O Show InChI InChI=1S/C17H32N2O2/c1-5-9-19-14-17(21-13-15(19)20)7-11-18(12-8-17)10-6-16(2,3)4/h5-14H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484128 (9-isopentyl-4-propyl-1-oxa- 4,9-diazaspiro[5.5]und...) Show SMILES CCCN1CC2(CCN(CCC(C)C)CC2)OCC1=O Show InChI InChI=1S/C16H30N2O2/c1-4-8-18-13-16(20-12-15(18)19)6-10-17(11-7-16)9-5-14(2)3/h14H,4-13H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484133 (9-isopentyl-2,2-dimethyl-4- propyl-1-oxa-4.9- diaz...) Show SMILES CCCN1CC2(CCN(CCC(C)C)CC2)OC(C)(C)C1=O Show InChI InChI=1S/C18H34N2O2/c1-6-10-20-14-18(22-17(4,5)16(20)21)8-12-19(13-9-18)11-7-15(2)3/h15H,6-14H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484134 ((S)-9-isopentyl-2-methyl-4- propyl-1-oxa-4,9- diaz...) Show SMILES CCCN1CC2(CCN(CCC(C)C)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C17H32N2O2/c1-5-9-19-13-17(21-15(4)16(19)20)7-11-18(12-8-17)10-6-14(2)3/h14-15H,5-13H2,1-4H3/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484146 (8-(4-fluorobenzyl)-12-methyl- 4-oxa-8,12- diazadis...) Show SMILES CN1CC2(CCN(Cc3ccc(F)cc3)CC2)OC2(CC2)C1=O Show InChI InChI=1S/C18H23FN2O2/c1-20-13-17(23-18(6-7-18)16(20)22)8-10-21(11-9-17)12-14-2-4-15(19)5-3-14/h2-5H,6-13H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484147 (4-ethyl-9-(4-fluorobenzyl)- 2,2-dimethyl-1-oxa-4,9...) Show SMILES CCN1CC2(CCN(Cc3ccc(F)cc3)CC2)OC(C)(C)C1=O Show InChI InChI=1S/C19H27FN2O2/c1-4-22-14-19(24-18(2,3)17(22)23)9-11-21(12-10-19)13-15-5-7-16(20)8-6-15/h5-8H,4,9-14H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484148 ((S)-9-(4-fluorobenzyl)-4- isopropyl-2-methyl-1-oxa...) Show SMILES CC(C)N1CC2(CCN(Cc3ccc(F)cc3)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C19H27FN2O2/c1-14(2)22-13-19(24-15(3)18(22)23)8-10-21(11-9-19)12-16-4-6-17(20)7-5-16/h4-7,14-15H,8-13H2,1-3H3/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484149 ((R)-4-ethyl-9-(4- fluorobenzyl)-2-methyl-1-oxa- 4,...) Show SMILES CCN1CC2(CCN(Cc3ccc(F)cc3)CC2)O[C@H](C)C1=O |r| Show InChI InChI=1S/C18H25FN2O2/c1-3-21-13-18(23-14(2)17(21)22)8-10-20(11-9-18)12-15-4-6-16(19)7-5-15/h4-7,14H,3,8-13H2,1-2H3/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484151 ((S)-9-(4-chlorobenzyl)-4- ethyl-2-methyl-1-oxa-4,9...) Show SMILES CCN1CC2(CCN(Cc3ccc(Cl)cc3)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C18H25ClN2O2/c1-3-21-13-18(23-14(2)17(21)22)8-10-20(11-9-18)12-15-4-6-16(19)7-5-15/h4-7,14H,3,8-13H2,1-2H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484152 ((R)-9-(4-chlorobenzyl)-4- ethyl-2-methyl-1-oxa-4,9...) Show SMILES CCN1CC2(CCN(Cc3ccc(Cl)cc3)CC2)O[C@H](C)C1=O |r| Show InChI InChI=1S/C18H25ClN2O2/c1-3-21-13-18(23-14(2)17(21)22)8-10-20(11-9-18)12-15-4-6-16(19)7-5-15/h4-7,14H,3,8-13H2,1-2H3/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484153 ((R)-4-((4-ethyl-2-methyl-3- oxo-1-oxa-4,9- diazasp...) Show SMILES CCN1CC2(CCN(Cc3ccc(cc3)C#N)CC2)O[C@H](C)C1=O |r| Show InChI InChI=1S/C19H25N3O2/c1-3-22-14-19(24-15(2)18(22)23)8-10-21(11-9-19)13-17-6-4-16(12-20)5-7-17/h4-7,15H,3,8-11,13-14H2,1-2H3/t15-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484155 (9-(4-chlorobenzyl)-4-ethyl- 2,2-dimethyl-1-oxa-4,9...) Show SMILES CCN1CC2(CCN(Cc3ccc(Cl)cc3)CC2)OC(C)(C)C1=O Show InChI InChI=1S/C19H27ClN2O2/c1-4-22-14-19(24-18(2,3)17(22)23)9-11-21(12-10-19)13-15-5-7-16(20)8-6-15/h5-8H,4,9-14H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484156 (4-((4-ethyl-2,2-dimethyl-3- oxo-1-oxa-4,9- diazasp...) Show SMILES CCN1CC2(CCN(Cc3ccc(cc3)C#N)CC2)OC(C)(C)C1=O Show InChI InChI=1S/C20H27N3O2/c1-4-23-15-20(25-19(2,3)18(23)24)9-11-22(12-10-20)14-17-7-5-16(13-21)6-8-17/h5-8H,4,9-12,14-15H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484160 ((S)-4-((4-ethyl-2-methyl-3- oxo-1-oxa-4,9- diazasp...) Show SMILES CCN1CC2(CCN(Cc3ccc(cc3)C#N)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C19H25N3O2/c1-3-22-14-19(24-15(2)18(22)23)8-10-21(11-9-19)13-17-6-4-16(12-20)5-7-17/h4-7,15H,3,8-11,13-14H2,1-2H3/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484162 ((S)-4-((4-isopropyl-2-methyl- 3-oxo-1-oxa-4,9- dia...) Show SMILES CC(C)N1CC2(CCN(Cc3ccc(cc3)C#N)CC2)O[C@@H](C)C1=O |r| Show InChI InChI=1S/C20H27N3O2/c1-15(2)23-14-20(25-16(3)19(23)24)8-10-22(11-9-20)13-18-6-4-17(12-21)5-7-18/h4-7,15-16H,8-11,13-14H2,1-3H3/t16-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484163 ((R)-9-(4-fluorobenzyl)-2,4- dimethyl-1-oxa-4,9- di...) Show SMILES C[C@H]1OC2(CCN(Cc3ccc(F)cc3)CC2)CN(C)C1=O |r| Show InChI InChI=1S/C17H23FN2O2/c1-13-16(21)19(2)12-17(22-13)7-9-20(10-8-17)11-14-3-5-15(18)6-4-14/h3-6,13H,7-12H2,1-2H3/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484165 ((S)-9-benzyl-4-cyclopropyl-2- methyl-1-oxa-4,9- di...) Show SMILES C[C@@H]1OC2(CCN(Cc3ccccc3)CC2)CN(C2CC2)C1=O |r| Show InChI InChI=1S/C19H26N2O2/c1-15-18(22)21(17-7-8-17)14-19(23-15)9-11-20(12-10-19)13-16-5-3-2-4-6-16/h2-6,15,17H,7-14H2,1H3/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484166 ((S)-4-((4-cyclopropyl-2- methyl-3-oxo-1-oxa-4,9- d...) Show SMILES C[C@@H]1OC2(CCN(Cc3ccc(cc3)C#N)CC2)CN(C2CC2)C1=O |r| Show InChI InChI=1S/C20H25N3O2/c1-15-19(24)23(18-6-7-18)14-20(25-15)8-10-22(11-9-20)13-17-4-2-16(12-21)3-5-17/h2-5,15,18H,6-11,13-14H2,1H3/t15-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484167 ((S)-4-((2,4-dimethyl-3-oxo-1- oxa-4,9- diazaspiro[...) Show SMILES C[C@@H]1OC2(CCN(Cc3ccc(cc3)C#N)CC2)CN(C)C1=O |r| Show InChI InChI=1S/C18H23N3O2/c1-14-17(22)20(2)13-18(23-14)7-9-21(10-8-18)12-16-5-3-15(11-19)4-6-16/h3-6,14H,7-10,12-13H2,1-2H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484180 (8-(2-(3-chloropyridin-2- yl)ethyl)-12-isobutyl-4-o...) Show SMILES CC(C)CN1CC2(CC2)OC2(CCN(CCc3ncccc3Cl)CC2)C1 Show InChI InChI=1S/C21H32ClN3O/c1-17(2)14-25-15-20(6-7-20)26-21(16-25)8-12-24(13-9-21)11-5-19-18(22)4-3-10-23-19/h3-4,10,17H,5-9,11-16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484181 (2-(2-(12-isobutyl-4-oxa-8,12- diazadispiro[2.1.5.3...) Show SMILES CC(C)CN1CC2(CC2)OC2(CCN(CCc3ncccc3C#N)CC2)C1 Show InChI InChI=1S/C22H32N4O/c1-18(2)15-26-16-21(6-7-21)27-22(17-26)8-12-25(13-9-22)11-5-20-19(14-23)4-3-10-24-20/h3-4,10,18H,5-9,11-13,15-17H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484182 (8-(2-(3-fluoropyridin-2- yl)ethyl)-12-isopentyl-4-...) Show SMILES CC(C)CCN1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1 Show InChI InChI=1S/C22H34FN3O/c1-18(2)5-12-26-16-21(7-8-21)27-22(17-26)9-14-25(15-10-22)13-6-20-19(23)4-3-11-24-20/h3-4,11,18H,5-10,12-17H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484183 (8-(2-(3-fluoropyridin-2- yl)ethyl)-12-neopentyl-4-...) Show SMILES CC(C)(C)CN1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1 Show InChI InChI=1S/C22H34FN3O/c1-20(2,3)15-26-16-21(7-8-21)27-22(17-26)9-13-25(14-10-22)12-6-19-18(23)5-4-11-24-19/h4-5,11H,6-10,12-17H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484184 (12-(sec-butyl)-8-(2-(3- fluoropyridin-2-yl)ethyl)-...) Show SMILES CCC(C)N1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1 Show InChI InChI=1S/C21H32FN3O/c1-3-17(2)25-15-20(7-8-20)26-21(16-25)9-13-24(14-10-21)12-6-19-18(22)5-4-11-23-19/h4-5,11,17H,3,6-10,12-16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair
AP-4 complex subunit sigma-1 (Homo sapiens (Human))	BDBM484187 ((S)-9-(2-(3-fluoropyridin-2- yl)ethyl)-2-methyl-4-...) Show SMILES CCCN1C[C@H](C)OC2(CCN(CCc3ncccc3F)CC2)C1 |r| Show InChI InChI=1S/C19H30FN3O/c1-3-10-23-14-16(2)24-19(15-23)7-12-22(13-8-19)11-6-18-17(20)5-4-9-21-18/h4-5,9,16H,3,6-8,10-15H2,1-2H3/t16-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS. S.A. US Patent					Assay Description To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...				US Patent US10927128 (2021) BindingDB Entry DOI: 10.7270/Q28918ZF
					More data for this Ligand-Target Pair

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