Found 35 hits Enz. Inhib. hit(s) with all data for entry = 6360 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124241
(N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(1-...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccco2)cc1)C1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C34H34N4O6/c39-31(25-13-17-37(18-14-25)33(41)29-3-1-21-43-29)35-27-9-5-23(6-10-27)24-7-11-28(12-8-24)36-32(40)26-15-19-38(20-16-26)34(42)30-4-2-22-44-30/h1-12,21-22,25-26H,13-20H2,(H,35,39)(H,36,40) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124240
(N,N'-(biphenyl-4,4'-diyl)bis(1-benzoylpipe...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccccc2)cc1)C1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C38H38N4O4/c43-35(29-19-23-41(24-20-29)37(45)31-7-3-1-4-8-31)39-33-15-11-27(12-16-33)28-13-17-34(18-14-28)40-36(44)30-21-25-42(26-22-30)38(46)32-9-5-2-6-10-32/h1-18,29-30H,19-26H2,(H,39,43)(H,40,44) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124246
(4-(4-benzamidophenyl)-N-phenylbenzamide (25))Show SMILES O=C(Nc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H20N2O2/c29-25(21-7-3-1-4-8-21)28-24-17-15-20(16-18-24)19-11-13-22(14-12-19)26(30)27-23-9-5-2-6-10-23/h1-18H,(H,27,30)(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124239
(N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(1-...)Show SMILES Fc1ccc(cc1)C(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C38H36F2N4O4/c39-31-9-1-29(2-10-31)37(47)43-21-17-27(18-22-43)35(45)41-33-13-5-25(6-14-33)26-7-15-34(16-8-26)42-36(46)28-19-23-44(24-20-28)38(48)30-3-11-32(40)12-4-30/h1-16,27-28H,17-24H2,(H,41,45)(H,42,46) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124248
(N-(6-(4-benzamidophenyl)pyridin-3-yl)benzamide (28...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)c2ccccc2)cn1)c1ccccc1 Show InChI InChI=1S/C25H19N3O2/c29-24(19-7-3-1-4-8-19)27-21-13-11-18(12-14-21)23-16-15-22(17-26-23)28-25(30)20-9-5-2-6-10-20/h1-17H,(H,27,29)(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124249
(4-fluoro-N-(6-(4-(4-fluorobenzamido)phenyl)pyridin...)Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)c2ccc(F)cc2)cn1 Show InChI InChI=1S/C25H17F2N3O2/c26-19-7-1-17(2-8-19)24(31)29-21-11-5-16(6-12-21)23-14-13-22(15-28-23)30-25(32)18-3-9-20(27)10-4-18/h1-15H,(H,29,31)(H,30,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124250
(N-(6-(4-(cyclohexanecarboxamido)phenyl)pyridin-3-y...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCCCC2)cn1)C1CCCCC1 Show InChI InChI=1S/C25H31N3O2/c29-24(19-7-3-1-4-8-19)27-21-13-11-18(12-14-21)23-16-15-22(17-26-23)28-25(30)20-9-5-2-6-10-20/h11-17,19-20H,1-10H2,(H,27,29)(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM124240
(N,N'-(biphenyl-4,4'-diyl)bis(1-benzoylpipe...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccccc2)cc1)C1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C38H38N4O4/c43-35(29-19-23-41(24-20-29)37(45)31-7-3-1-4-8-31)39-33-15-11-27(12-16-33)28-13-17-34(18-14-28)40-36(44)30-21-25-42(26-22-30)38(46)32-9-5-2-6-10-32/h1-18,29-30H,19-26H2,(H,39,43)(H,40,44) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124238
(di-tert-butyl4,4'-(([1,1'-biphenyl]-4,4...)Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C34H46N4O6/c1-33(2,3)43-31(41)37-19-15-25(16-20-37)29(39)35-27-11-7-23(8-12-27)24-9-13-28(14-10-24)36-30(40)26-17-21-38(22-18-26)32(42)44-34(4,5)6/h7-14,25-26H,15-22H2,1-6H3,(H,35,39)(H,36,40) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124245
(Methyl 4-(4-benzamidophenyl)benzoate (23))Show InChI InChI=1S/C21H17NO3/c1-25-21(24)18-9-7-15(8-10-18)16-11-13-19(14-12-16)22-20(23)17-5-3-2-4-6-17/h2-14H,1H3,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124247
(N-(6-(4-(furan-2-carboxamido)phenyl)pyridin-3-yl)f...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)c2ccco2)cn1)c1ccco1 Show InChI InChI=1S/C21H15N3O4/c25-20(18-3-1-11-27-18)23-15-7-5-14(6-8-15)17-10-9-16(13-22-17)24-21(26)19-4-2-12-28-19/h1-13H,(H,23,25)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124234
(N,N'-(biphenyl-4,4'-diyl)dibenzamide (3))Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)c2ccccc2)cc1)c1ccccc1 Show InChI InChI=1S/C26H20N2O2/c29-25(21-7-3-1-4-8-21)27-23-15-11-19(12-16-23)20-13-17-24(18-14-20)28-26(30)22-9-5-2-6-10-22/h1-18H,(H,27,29)(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124243
(N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(1-...)Show SMILES CC(C)CC(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)CC(C)C)cc1 Show InChI InChI=1S/C34H46N4O4/c1-23(2)21-31(39)37-17-13-27(14-18-37)33(41)35-29-9-5-25(6-10-29)26-7-11-30(12-8-26)36-34(42)28-15-19-38(20-16-28)32(40)22-24(3)4/h5-12,23-24,27-28H,13-22H2,1-4H3,(H,35,41)(H,36,42) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM124241
(N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(1-...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccco2)cc1)C1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C34H34N4O6/c39-31(25-13-17-37(18-14-25)33(41)29-3-1-21-43-29)35-27-9-5-23(6-10-27)24-7-11-28(12-8-24)36-32(40)26-15-19-38(20-16-26)34(42)30-4-2-22-44-30/h1-12,21-22,25-26H,13-20H2,(H,35,39)(H,36,40) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124236
(N,N'-([1,1'-biphenyl]-4,4'-diyl)dicycl...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCCCC2)cc1)C1CCCCC1 Show InChI InChI=1S/C26H32N2O2/c29-25(21-7-3-1-4-8-21)27-23-15-11-19(12-16-23)20-13-17-24(18-14-20)28-26(30)22-9-5-2-6-10-22/h11-18,21-22H,1-10H2,(H,27,29)(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124242
(N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(1-...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)C2CCCCC2)cc1)C1CCN(CC1)C(=O)C1CCCCC1 Show InChI InChI=1S/C38H50N4O4/c43-35(29-19-23-41(24-20-29)37(45)31-7-3-1-4-8-31)39-33-15-11-27(12-16-33)28-13-17-34(18-14-28)40-36(44)30-21-25-42(26-22-30)38(46)32-9-5-2-6-10-32/h11-18,29-32H,1-10,19-26H2,(H,39,43)(H,40,44) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 6
(Homo sapiens (Human)) | BDBM50391109
(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124237
(N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(3-...)Show SMILES CC(C)CC(=O)Nc1ccc(cc1)-c1ccc(NC(=O)CC(C)C)cc1 Show InChI InChI=1S/C22H28N2O2/c1-15(2)13-21(25)23-19-9-5-17(6-10-19)18-7-11-20(12-8-18)24-22(26)14-16(3)4/h5-12,15-16H,13-14H2,1-4H3,(H,23,25)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase F
(Homo sapiens (Human)) | BDBM50391109
(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 6
(Homo sapiens (Human)) | BDBM124249
(4-fluoro-N-(6-(4-(4-fluorobenzamido)phenyl)pyridin...)Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)c2ccc(F)cc2)cn1 Show InChI InChI=1S/C25H17F2N3O2/c26-19-7-1-17(2-8-19)24(31)29-21-11-5-16(6-12-21)23-14-13-22(15-28-23)30-25(32)18-3-9-20(27)10-4-18/h1-15H,(H,29,31)(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 6
(Homo sapiens (Human)) | BDBM124238
(di-tert-butyl4,4'-(([1,1'-biphenyl]-4,4...)Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C34H46N4O6/c1-33(2,3)43-31(41)37-19-15-25(16-20-37)29(39)35-27-11-7-23(8-12-27)24-9-13-28(14-10-24)36-30(40)26-17-21-38(22-18-26)32(42)44-34(4,5)6/h7-14,25-26H,15-22H2,1-6H3,(H,35,39)(H,36,40) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124244
(N-phenyl-4-[4-(phenylcarbamoyl)phenyl]benzamide (2...)Show SMILES O=C(Nc1ccccc1)c1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C26H20N2O2/c29-25(27-23-7-3-1-4-8-23)21-15-11-19(12-16-21)20-13-17-22(18-14-20)26(30)28-24-9-5-2-6-10-24/h1-18H,(H,27,29)(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124235
(N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(4-...)Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C26H18F2N2O2/c27-21-9-1-19(2-10-21)25(31)29-23-13-5-17(6-14-23)18-7-15-24(16-8-18)30-26(32)20-3-11-22(28)12-4-20/h1-16H,(H,29,31)(H,30,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124233
(N‐{4‐[4‐(furan‐2‐ami...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)c2ccco2)cc1)c1ccco1 Show InChI InChI=1S/C22H16N2O4/c25-21(19-3-1-13-27-19)23-17-9-5-15(6-10-17)16-7-11-18(12-8-16)24-22(26)20-4-2-14-28-20/h1-14H,(H,23,25)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human)) | BDBM124249
(4-fluoro-N-(6-(4-(4-fluorobenzamido)phenyl)pyridin...)Show SMILES Fc1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)c2ccc(F)cc2)cn1 Show InChI InChI=1S/C25H17F2N3O2/c26-19-7-1-17(2-8-19)24(31)29-21-11-5-16(6-12-21)23-14-13-22(15-28-23)30-25(32)18-3-9-20(27)10-4-18/h1-15H,(H,29,31)(H,30,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM124238
(di-tert-butyl4,4'-(([1,1'-biphenyl]-4,4...)Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)OC(C)(C)C)cc1 Show InChI InChI=1S/C34H46N4O6/c1-33(2,3)43-31(41)37-19-15-25(16-20-37)29(39)35-27-11-7-23(8-12-27)24-9-13-28(14-10-24)36-30(40)26-17-21-38(22-18-26)32(42)44-34(4,5)6/h7-14,25-26H,15-22H2,1-6H3,(H,35,39)(H,36,40) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM124250
(N-(6-(4-(cyclohexanecarboxamido)phenyl)pyridin-3-y...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCCCC2)cn1)C1CCCCC1 Show InChI InChI=1S/C25H31N3O2/c29-24(19-7-3-1-4-8-19)27-21-13-11-18(12-14-21)23-16-15-22(17-26-23)28-25(30)20-9-5-2-6-10-20/h11-17,19-20H,1-10H2,(H,27,29)(H,28,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM124248
(N-(6-(4-benzamidophenyl)pyridin-3-yl)benzamide (28...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)c2ccccc2)cn1)c1ccccc1 Show InChI InChI=1S/C25H19N3O2/c29-24(19-7-3-1-4-8-19)27-21-13-11-18(12-14-21)23-16-15-22(17-26-23)28-25(30)20-9-5-2-6-10-20/h1-17H,(H,27,29)(H,28,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124251
(3-methyl-N-(6-(4-(3-methylbutanamido)phenyl)pyridi...)Show SMILES CC(C)CC(=O)Nc1ccc(cc1)-c1ccc(NC(=O)CC(C)C)cn1 Show InChI InChI=1S/C21H27N3O2/c1-14(2)11-20(25)23-17-7-5-16(6-8-17)19-10-9-18(13-22-19)24-21(26)12-15(3)4/h5-10,13-15H,11-12H2,1-4H3,(H,23,25)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human)) | BDBM50391109
(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 6
(Homo sapiens (Human)) | BDBM124233
(N‐{4‐[4‐(furan‐2‐ami...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)c2ccco2)cc1)c1ccco1 Show InChI InChI=1S/C22H16N2O4/c25-21(19-3-1-13-27-19)23-17-9-5-15(6-10-17)16-7-11-18(12-8-16)24-22(26)20-4-2-14-28-20/h1-14H,(H,23,25)(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM124233
(N‐{4‐[4‐(furan‐2‐ami...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)c2ccco2)cc1)c1ccco1 Show InChI InChI=1S/C22H16N2O4/c25-21(19-3-1-13-27-19)23-17-9-5-15(6-10-17)16-7-11-18(12-8-16)24-22(26)20-4-2-14-28-20/h1-14H,(H,23,25)(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human)) | BDBM124233
(N‐{4‐[4‐(furan‐2‐ami...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)c2ccco2)cc1)c1ccco1 Show InChI InChI=1S/C22H16N2O4/c25-21(19-3-1-13-27-19)23-17-9-5-15(6-10-17)16-7-11-18(12-8-16)24-22(26)20-4-2-14-28-20/h1-14H,(H,23,25)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Search and Browse
