Compile Data Set for Download or QSAR

Found 66 hits of ic50 data for polymerid = 50006148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393129 (CHEMBL2153461) Show SMILES C[C@H](NC(=O)Cc1ccc(cc1)-c1ccc2cccnc2n1)c1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C31H23F4N3O/c1-19(21-8-10-22(11-9-21)25-12-14-27(32)26(18-25)31(33,34)35)37-29(39)17-20-4-6-23(7-5-20)28-15-13-24-3-2-16-36-30(24)38-28/h2-16,18-19H,17H2,1H3,(H,37,39)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393123 (CHEMBL2153446) Show SMILES C[C@H](NC(=O)CCCc1ccc2cccnc2n1)c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C26H24ClN3O/c1-18(19-10-12-20(13-11-19)22-5-2-7-23(27)17-22)29-25(31)9-3-8-24-15-14-21-6-4-16-28-26(21)30-24/h2,4-7,10-18H,3,8-9H2,1H3,(H,29,31)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393133 (CHEMBL2153465) Show SMILES C[C@H](NC(=O)C(C)(C)c1ccc(cc1)-c1ccc2cccnc2n1)c1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C33H27F4N3O/c1-20(21-6-8-22(9-7-21)25-12-16-28(34)27(19-25)33(35,36)37)39-31(41)32(2,3)26-14-10-23(11-15-26)29-17-13-24-5-4-18-38-30(24)40-29/h4-20H,1-3H3,(H,39,41)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393122 (CHEMBL2153445) Show SMILES CC(NC(=O)CCCc1ccc2cccnc2n1)c1ccc(cc1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H24F3N3O/c1-18(19-10-12-20(13-11-19)22-5-2-7-23(17-22)27(28,29)30)32-25(34)9-3-8-24-15-14-21-6-4-16-31-26(21)33-24/h2,4-7,10-18H,3,8-9H2,1H3,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393136 (CHEMBL2153468) Show SMILES C[C@H](NC(=O)C(O)(c1ccc(cc1)-c1ccc2cccnc2n1)C(F)(F)F)c1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C32H22F7N3O2/c1-18(19-4-6-20(7-5-19)23-10-14-26(33)25(17-23)31(34,35)36)41-29(43)30(44,32(37,38)39)24-12-8-21(9-13-24)27-15-11-22-3-2-16-40-28(22)42-27/h2-18,44H,1H3,(H,41,43)/t18-,30?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393130 (CHEMBL2153462) Show SMILES CC(C)(C(=O)NCc1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F)c1ccc(cc1)-c1ccc2cccnc2n1 Show InChI InChI=1S/C32H25F4N3O/c1-31(2,25-13-9-22(10-14-25)28-16-12-23-4-3-17-37-29(23)39-28)30(40)38-19-20-5-7-21(8-6-20)24-11-15-27(33)26(18-24)32(34,35)36/h3-18H,19H2,1-2H3,(H,38,40)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393135 (CHEMBL2153467) Show SMILES C[C@H](NC(=O)C(O)c1ccc(cc1)-c1ccc2cccnc2n1)c1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C31H23F4N3O2/c1-18(19-4-6-20(7-5-19)24-12-14-26(32)25(17-24)31(33,34)35)37-30(40)28(39)22-10-8-21(9-11-22)27-15-13-23-3-2-16-36-29(23)38-27/h2-18,28,39H,1H3,(H,37,40)/t18-,28?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393134 (CHEMBL2153466) Show SMILES C[C@H](NC(=O)C(F)(F)c1ccc(cc1)-c1ccc2cccnc2n1)c1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C31H21F6N3O/c1-18(19-4-6-20(7-5-19)23-10-14-26(32)25(17-23)31(35,36)37)39-29(41)30(33,34)24-12-8-21(9-13-24)27-15-11-22-3-2-16-38-28(22)40-27/h2-18H,1H3,(H,39,41)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393118 (CHEMBL2153441) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C26H21F4N3O/c27-23-13-11-20(15-22(23)26(28,29)30)18-8-6-17(7-9-18)16-32-24(34)5-1-4-21-12-10-19-3-2-14-31-25(19)33-21/h2-3,6-15H,1,4-5,16H2,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561194 (CHEMBL4790324) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cccc(c2)C(=O)Nc2ccccc2CC(O)=O)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393161 (CHEMBL2153439) Show SMILES Cc1cccc(c1)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C26H25N3O/c1-19-5-2-6-23(17-19)21-12-10-20(11-13-21)18-28-25(30)9-3-8-24-15-14-22-7-4-16-27-26(22)29-24/h2,4-7,10-17H,3,8-9,18H2,1H3,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393127 (CHEMBL2153459) Show SMILES Fc1ccc(cc1Cl)-c1ccc(CNC(=O)Cc2ccc(cc2)-c2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C29H21ClFN3O/c30-25-17-24(11-13-26(25)31)21-7-5-20(6-8-21)18-33-28(35)16-19-3-9-22(10-4-19)27-14-12-23-2-1-15-32-29(23)34-27/h1-15,17H,16,18H2,(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393131 (CHEMBL2153463) Show SMILES OC(C(=O)NCc1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F)(c1ccc(cc1)-c1ccc2cccnc2n1)C(F)(F)F Show InChI InChI=1S/C31H20F7N3O2/c32-25-13-9-22(16-24(25)30(33,34)35)19-5-3-18(4-6-19)17-40-28(42)29(43,31(36,37)38)23-11-7-20(8-12-23)26-14-10-21-2-1-15-39-27(21)41-26/h1-16,43H,17H2,(H,40,42)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393143 (CHEMBL2153581) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1cc(CNC(=O)CCCc2ccc3cccnc3n2)on1 Show InChI InChI=1S/C23H18F4N4O2/c24-19-9-7-15(11-18(19)23(25,26)27)20-12-17(33-31-20)13-29-21(32)5-1-4-16-8-6-14-3-2-10-28-22(14)30-16/h2-3,6-12H,1,4-5,13H2,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393119 (CHEMBL2153442) Show SMILES Fc1ccc(cc1Cl)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C25H21ClFN3O/c26-22-15-20(11-13-23(22)27)18-8-6-17(7-9-18)16-29-24(31)5-1-4-21-12-10-19-3-2-14-28-25(19)30-21/h2-3,6-15H,1,4-5,16H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393117 (CHEMBL2153440) Show SMILES Clc1cccc(c1)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C25H22ClN3O/c26-22-6-1-4-21(16-22)19-11-9-18(10-12-19)17-28-24(30)8-2-7-23-14-13-20-5-3-15-27-25(20)29-23/h1,3-6,9-16H,2,7-8,17H2,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393148 (CHEMBL2153586) Show SMILES Clc1cccc(c1)-c1ccc(cc1)-c1nnc(CCCc2ccc3cccnc3n2)o1 Show InChI InChI=1S/C25H19ClN4O/c26-21-6-1-4-20(16-21)17-9-11-19(12-10-17)25-30-29-23(31-25)8-2-7-22-14-13-18-5-3-15-27-24(18)28-22/h1,3-6,9-16H,2,7-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393120 (CHEMBL2153443) Show SMILES Fc1cc(ccc1CNC(=O)CCCc1ccc2cccnc2n1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C26H21F4N3O/c27-23-15-19(18-4-1-6-21(14-18)26(28,29)30)9-10-20(23)16-32-24(34)8-2-7-22-12-11-17-5-3-13-31-25(17)33-22/h1,3-6,9-15H,2,7-8,16H2,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393137 (CHEMBL2153469) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1ncc(CNC(=O)CCCc2ccc3cccnc3n2)cn1 Show InChI InChI=1S/C24H19F4N5O/c25-20-9-7-17(11-19(20)24(26,27)28)22-31-13-15(14-32-22)12-30-21(34)5-1-4-18-8-6-16-3-2-10-29-23(16)33-18/h2-3,6-11,13-14H,1,4-5,12H2,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393121 (CHEMBL2153444) Show SMILES CCc1cccc(c1)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C27H27N3O/c1-2-20-6-3-7-24(18-20)22-13-11-21(12-14-22)19-29-26(31)10-4-9-25-16-15-23-8-5-17-28-27(23)30-25/h3,5-8,11-18H,2,4,9-10,19H2,1H3,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393141 (CHEMBL2153579) Show SMILES Clc1cccc(c1)-c1cc(CNC(=O)CCCc2ccc3cccnc3n2)on1 Show InChI InChI=1S/C22H19ClN4O2/c23-17-6-1-4-16(12-17)20-13-19(29-27-20)14-25-21(28)8-2-7-18-10-9-15-5-3-11-24-22(15)26-18/h1,3-6,9-13H,2,7-8,14H2,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393128 (CHEMBL2153460) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1ccc(CNC(=O)Cc2ccc(cc2)-c2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C30H21F4N3O/c31-26-13-11-24(17-25(26)30(32,33)34)21-7-5-20(6-8-21)18-36-28(38)16-19-3-9-22(10-4-19)27-14-12-23-2-1-15-35-29(23)37-27/h1-15,17H,16,18H2,(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561202 (CHEMBL4763307) Show SMILES OC(=O)Cc1ccccc1NC(=O)c1cccc(c1)-c1ccc(Cl)c(O[C@@H]2CCCNC2)c1F |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561205 (CHEMBL4751488) Show SMILES OC(=O)Cc1cc(F)ccc1NC(=O)c1cccc(c1F)-c1cc(O[C@@H]2CCCNC2)c(Cl)cc1F |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561204 (CHEMBL4757124) Show SMILES OC(=O)Cc1cc(F)ccc1NC(=O)c1cccc(c1)-c1cc(O[C@@H]2CCCNC2)c(Cl)cc1F |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393142 (CHEMBL2153580) Show SMILES Fc1ccc(cc1Cl)-c1cc(CNC(=O)CCCc2ccc3cccnc3n2)on1 Show InChI InChI=1S/C22H18ClFN4O2/c23-18-11-15(7-9-19(18)24)20-12-17(30-28-20)13-26-21(29)5-1-4-16-8-6-14-3-2-10-25-22(14)27-16/h2-3,6-12H,1,4-5,13H2,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561203 (CHEMBL4752851) Show SMILES OC(=O)Cc1cc(F)ccc1NC(=O)c1cccc(c1)-c1ccc(Cl)c(O[C@@H]2CCCNC2)c1F |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393149 (CHEMBL2153587) Show SMILES Fc1ccc(cc1Cl)-c1ccc(cc1)-c1nnc(CCCc2ccc3cccnc3n2)o1 Show InChI InChI=1S/C25H18ClFN4O/c26-21-15-19(11-13-22(21)27)16-6-8-18(9-7-16)25-31-30-23(32-25)5-1-4-20-12-10-17-3-2-14-28-24(17)29-20/h2-3,6-15H,1,4-5H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561199 (CHEMBL4745252) Show SMILES OC(=O)Cc1ccccc1NC(=O)c1cccc(c1)-c1ccc(Cl)c(OC2CCNCC2)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561198 (CHEMBL4783334) Show SMILES OC(=O)Cc1ccccc1NC(=O)c1cccc(c1)-c1ccc(Cl)c(OC2CCNC2)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561197 (CHEMBL4791540) Show SMILES OC(=O)Cc1ccccc1NC(=O)c1cccc(c1)-c1ccc(Cl)c(OC2CNC2)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393158 (CHEMBL2153596) Show SMILES FC(F)(F)c1cc(ccc1Cl)-c1nnc(CCCCc2ccc3cccnc3n2)o1 Show InChI InChI=1S/C21H16ClF3N4O/c22-17-10-8-14(12-16(17)21(23,24)25)20-29-28-18(30-20)6-2-1-5-15-9-7-13-4-3-11-26-19(13)27-15/h3-4,7-12H,1-2,5-6H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393156 (CHEMBL2153594) Show SMILES FC(F)(F)c1ccc(cc1C(F)(F)F)-c1nnc(CCCCc2ccc3cccnc3n2)o1 Show InChI InChI=1S/C22H16F6N4O/c23-21(24,25)16-10-8-14(12-17(16)22(26,27)28)20-32-31-18(33-20)6-2-1-5-15-9-7-13-4-3-11-29-19(13)30-15/h3-4,7-12H,1-2,5-6H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393157 (CHEMBL2153595) Show SMILES FC(F)(F)Oc1ccc(cc1Cl)-c1nnc(CCCCc2ccc3cccnc3n2)o1 Show InChI InChI=1S/C21H16ClF3N4O2/c22-16-12-14(8-10-17(16)31-21(23,24)25)20-29-28-18(30-20)6-2-1-5-15-9-7-13-4-3-11-26-19(13)27-15/h3-4,7-12H,1-2,5-6H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561201 (CHEMBL4755411) Show SMILES OC(=O)Cc1ccccc1NC(=O)c1cccc(c1F)-c1ccc(Cl)c(O[C@@H]2CCCNC2)c1 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393138 (CHEMBL2153470) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1cnc(CNC(=O)CCCc2ccc3cccnc3n2)nc1 Show InChI InChI=1S/C24H19F4N5O/c25-20-9-7-16(11-19(20)24(26,27)28)17-12-30-21(31-13-17)14-32-22(34)5-1-4-18-8-6-15-3-2-10-29-23(15)33-18/h2-3,6-13H,1,4-5,14H2,(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393150 (CHEMBL2153588) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)-c1nnc(CCCc2ccc3cccnc3n2)o1 Show InChI InChI=1S/C26H19F3N4O/c27-26(28,29)21-6-1-4-20(16-21)17-9-11-19(12-10-17)25-33-32-23(34-25)8-2-7-22-14-13-18-5-3-15-30-24(18)31-22/h1,3-6,9-16H,2,7-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393140 (CHEMBL2153472) Show SMILES Fc1ccc(cc1C(F)(F)F)-n1cc(CNC(=O)CCCc2ccc3cccnc3n2)cn1 Show InChI InChI=1S/C23H19F4N5O/c24-20-9-8-18(11-19(20)23(25,26)27)32-14-15(13-30-32)12-29-21(33)5-1-4-17-7-6-16-3-2-10-28-22(16)31-17/h2-3,6-11,13-14H,1,4-5,12H2,(H,29,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561196 (CHEMBL4781889) Show SMILES NCCOc1cc(ccc1Cl)-c1cccc(c1)C(=O)Nc1ccccc1CC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393147 (CHEMBL2153585) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1nnc(CNC(=O)CCCc2ccc3cccnc3n2)s1 Show InChI InChI=1S/C22H17F4N5OS/c23-17-9-7-14(11-16(17)22(24,25)26)21-31-30-19(33-21)12-28-18(32)5-1-4-15-8-6-13-3-2-10-27-20(13)29-15/h2-3,6-11H,1,4-5,12H2,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561195 (CHEMBL4743401) Show SMILES NCc1cc(ccc1Cl)-c1cccc(c1)C(=O)Nc1ccccc1CC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393145 (CHEMBL2153583) Show SMILES Clc1cccc(c1)-c1csc(CNC(=O)CCCc2ccc3cccnc3n2)n1 Show InChI InChI=1S/C22H19ClN4OS/c23-17-6-1-4-16(12-17)19-14-29-21(27-19)13-25-20(28)8-2-7-18-10-9-15-5-3-11-24-22(15)26-18/h1,3-6,9-12,14H,2,7-8,13H2,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393126 (CHEMBL2153457) Show SMILES Cc1cc(ccc1Cl)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C26H24ClN3O/c1-18-16-22(12-14-24(18)27)20-9-7-19(8-10-20)17-29-25(31)6-2-5-23-13-11-21-4-3-15-28-26(21)30-23/h3-4,7-16H,2,5-6,17H2,1H3,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393132 (CHEMBL2153464) Show SMILES NC(C(=O)NCc1ccc(cc1)-c1ccc(F)c(c1)C(F)(F)F)c1ccc(cc1)-c1ccc2cccnc2n1 Show InChI InChI=1S/C30H22F4N4O/c31-25-13-11-23(16-24(25)30(32,33)34)19-5-3-18(4-6-19)17-37-29(39)27(35)21-9-7-20(8-10-21)26-14-12-22-2-1-15-36-28(22)38-26/h1-16,27H,17,35H2,(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393125 (CHEMBL2153448) Show SMILES FC(F)(F)Oc1cccc(c1)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)cc1 Show InChI InChI=1S/C26H22F3N3O2/c27-26(28,29)34-23-7-1-4-21(16-23)19-11-9-18(10-12-19)17-31-24(33)8-2-6-22-14-13-20-5-3-15-30-25(20)32-22/h1,3-5,7,9-16H,2,6,8,17H2,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50561200 (CHEMBL4759141) Show SMILES OC(=O)Cc1ccccc1NC(=O)c1cccc(c1)-c1ccc(Cl)c(OC2CCCNC2)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01020 BindingDB Entry DOI: 10.7270/Q20K2D8S
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393144 (CHEMBL2153582) Show SMILES Clc1cccc(c1)-c1nc(CNC(=O)CCCc2ccc3cccnc3n2)cs1 Show InChI InChI=1S/C22H19ClN4OS/c23-17-6-1-4-16(12-17)22-27-19(14-29-22)13-25-20(28)8-2-7-18-10-9-15-5-3-11-24-21(15)26-18/h1,3-6,9-12,14H,2,7-8,13H2,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393139 (CHEMBL2153471) Show SMILES Fc1ccc(cc1C(F)(F)F)-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)nn1 Show InChI InChI=1S/C24H19F4N5O/c25-20-10-7-16(13-19(20)24(26,27)28)21-11-9-18(32-33-21)14-30-22(34)5-1-4-17-8-6-15-3-2-12-29-23(15)31-17/h2-3,6-13H,1,4-5,14H2,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393162 (CHEMBL2153436) Show SMILES COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)c(F)c1 Show InChI InChI=1S/C27H23F2N3O3/c1-35-27(34)25-21(7-3-8-22(25)28)18-10-11-19(23(29)15-18)16-31-24(33)9-2-6-20-13-12-17-5-4-14-30-26(17)32-20/h3-5,7-8,10-15H,2,6,9,16H2,1H3,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair
Succinate receptor 1 (Homo sapiens (Human))	BDBM50393152 (CHEMBL2153590) Show SMILES Fc1ccc(cc1Cl)-c1ccc(cc1)-c1nnc(CCCc2ccc3cccnc3n2)[nH]1 Show InChI InChI=1S/C25H19ClFN5/c26-21-15-19(11-13-22(21)27)16-6-8-18(9-7-16)25-30-23(31-32-25)5-1-4-20-12-10-17-3-2-14-28-24(17)29-20/h2-3,6-15H,1,4-5H2,(H,30,31,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...				Bioorg Med Chem Lett 21: 3596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.04.091 BindingDB Entry DOI: 10.7270/Q2BK1DG6
					More data for this Ligand-Target Pair

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