Found 52 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079561
(CHEMBL3417485)Show SMILES CN1CCN(CCOc2cnc(nc2)-c2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1 Show InChI InChI=1S/C30H30FN7O2/c1-35-11-13-36(14-12-35)15-16-40-26-19-32-30(33-20-26)24-4-2-3-22(17-24)21-38-29(39)8-7-28(34-38)37-10-9-23-5-6-25(31)18-27(23)37/h2-10,17-20H,11-16,21H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079560
(CHEMBL3417484)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(Cc4cccc(c4)-c4ncc(OCCN5CCOCC5)cn4)n3)c2c1 Show InChI InChI=1S/C29H27FN6O3/c30-24-5-4-22-8-9-35(26(22)17-24)27-6-7-28(37)36(33-27)20-21-2-1-3-23(16-21)29-31-18-25(19-32-29)39-15-12-34-10-13-38-14-11-34/h1-9,16-19H,10-15,20H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079566
(CHEMBL3414602)Show SMILES COCCOc1ccc2c(OCCn3nc(ccc3=O)-n3ccc4ccc(F)cc34)ccnc2c1 Show InChI InChI=1S/C26H23FN4O4/c1-33-14-15-34-20-4-5-21-22(17-20)28-10-8-24(21)35-13-12-31-26(32)7-6-25(29-31)30-11-9-18-2-3-19(27)16-23(18)30/h2-11,16-17H,12-15H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079563
(CHEMBL3417487)Show SMILES COCCCOc1cnc(nc1)-c1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C27H24FN5O3/c1-35-12-3-13-36-23-16-29-27(30-17-23)21-5-2-4-19(14-21)18-33-26(34)9-8-25(31-33)32-11-10-20-6-7-22(28)15-24(20)32/h2,4-11,14-17H,3,12-13,18H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50306682
((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)Show SMILES C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079558
(CHEMBL3417482)Show SMILES CN1CCN(CCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1 Show InChI InChI=1S/C28H31FN6O3/c1-32-13-15-33(16-14-32)11-3-17-38-28(37)30-24-5-2-4-21(18-24)20-35-27(36)9-8-26(31-35)34-12-10-22-6-7-23(29)19-25(22)34/h2,4-10,12,18-19H,3,11,13-17,20H2,1H3,(H,30,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079562
(CHEMBL3417486)Show SMILES CN1CCN(CCCOc2cnc(nc2)-c2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1 Show InChI InChI=1S/C31H32FN7O2/c1-36-13-15-37(16-14-36)11-3-17-41-27-20-33-31(34-21-27)25-5-2-4-23(18-25)22-39-30(40)9-8-29(35-39)38-12-10-24-6-7-26(32)19-28(24)38/h2,4-10,12,18-21H,3,11,13-17,22H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079559
(CHEMBL3417483)Show SMILES CN1CCN(CCCCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1 Show InChI InChI=1S/C30H35FN6O3/c1-34-15-17-35(18-16-34)13-3-2-4-19-40-30(39)32-26-7-5-6-23(20-26)22-37-29(38)11-10-28(33-37)36-14-12-24-8-9-25(31)21-27(24)36/h5-12,14,20-21H,2-4,13,15-19,22H2,1H3,(H,32,39) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079564
(CHEMBL3417488)Show SMILES COc1cnc(nc1)-c1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C24H18FN5O2/c1-32-20-13-26-24(27-14-20)18-4-2-3-16(11-18)15-30-23(31)8-7-22(28-30)29-10-9-17-5-6-19(25)12-21(17)29/h2-14H,15H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079551
(CHEMBL3417475)Show SMILES CN(C)CCCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C27H30FN5O3/c1-31(2)14-4-3-5-16-36-27(35)29-23-8-6-7-20(17-23)19-33-26(34)12-11-25(30-33)32-15-13-21-9-10-22(28)18-24(21)32/h6-13,15,17-18H,3-5,14,16,19H2,1-2H3,(H,29,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079555
(CHEMBL3417479)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(Cc4cccc(NC(=O)OCCCCn5cccn5)c4)n3)c2c1 Show InChI InChI=1S/C27H25FN6O3/c28-22-8-7-21-11-15-33(24(21)18-22)25-9-10-26(35)34(31-25)19-20-5-3-6-23(17-20)30-27(36)37-16-2-1-13-32-14-4-12-29-32/h3-12,14-15,17-18H,1-2,13,16,19H2,(H,30,36) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079556
(CHEMBL3417480)Show SMILES CN1CCN(CCCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1 Show InChI InChI=1S/C29H33FN6O3/c1-33-14-16-34(17-15-33)12-2-3-18-39-29(38)31-25-6-4-5-22(19-25)21-36-28(37)10-9-27(32-36)35-13-11-23-7-8-24(30)20-26(23)35/h4-11,13,19-20H,2-3,12,14-18,21H2,1H3,(H,31,38) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079554
(CHEMBL3417478)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(Cc4cccc(NC(=O)OCCCCN5CCOCC5)c4)n3)c2c1 Show InChI InChI=1S/C28H30FN5O4/c29-23-7-6-22-10-12-33(25(22)19-23)26-8-9-27(35)34(31-26)20-21-4-3-5-24(18-21)30-28(36)38-15-2-1-11-32-13-16-37-17-14-32/h3-10,12,18-19H,1-2,11,13-17,20H2,(H,30,36) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079557
(CHEMBL3417481)Show SMILES COC(=O)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C26H25FN4O5/c1-35-25(33)7-2-3-14-36-26(34)28-21-6-4-5-18(15-21)17-31-24(32)11-10-23(29-31)30-13-12-19-8-9-20(27)16-22(19)30/h4-6,8-13,15-16H,2-3,7,14,17H2,1H3,(H,28,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079550
(CHEMBL3417474)Show SMILES CN(C)CCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C25H26FN5O3/c1-29(2)12-4-14-34-25(33)27-21-6-3-5-18(15-21)17-31-24(32)10-9-23(28-31)30-13-11-19-7-8-20(26)16-22(19)30/h3,5-11,13,15-16H,4,12,14,17H2,1-2H3,(H,27,33) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079548
(CHEMBL3417472)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C26H28FN5O3/c1-30(2)13-3-4-15-35-26(34)28-22-7-5-6-19(16-22)18-32-25(33)11-10-24(29-32)31-14-12-20-8-9-21(27)17-23(20)31/h5-12,14,16-17H,3-4,13,15,18H2,1-2H3,(H,28,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079552
(CHEMBL3417476)Show SMILES CN(C)CCOCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C26H28FN5O4/c1-30(2)12-13-35-14-15-36-26(34)28-22-5-3-4-19(16-22)18-32-25(33)9-8-24(29-32)31-11-10-20-6-7-21(27)17-23(20)31/h3-11,16-17H,12-15,18H2,1-2H3,(H,28,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079569
(CHEMBL3417493)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(cc23)C(F)(F)F)c1 Show InChI InChI=1S/C27H28F3N5O3/c1-33(2)13-3-4-15-38-26(37)31-22-7-5-6-19(16-22)18-35-25(36)11-10-24(32-35)34-14-12-20-8-9-21(17-23(20)34)27(28,29)30/h5-12,14,16-17H,3-4,13,15,18H2,1-2H3,(H,31,37) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079574
(CHEMBL3417498)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3c(F)cc(F)cc23)c1 Show InChI InChI=1S/C26H27F2N5O3/c1-31(2)11-3-4-13-36-26(35)29-20-7-5-6-18(14-20)17-33-25(34)9-8-24(30-33)32-12-10-21-22(28)15-19(27)16-23(21)32/h5-10,12,14-16H,3-4,11,13,17H2,1-2H3,(H,29,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079543
(CHEMBL3417467)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3cccc(F)c3)ccc2=O)c1 Show InChI InChI=1S/C24H28FN5O3/c1-29(2)13-3-4-14-33-24(32)27-20-9-5-7-18(15-20)17-30-23(31)12-11-22(28-30)26-21-10-6-8-19(25)16-21/h5-12,15-16H,3-4,13-14,17H2,1-2H3,(H,26,28)(H,27,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079571
(CHEMBL3417495)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(C)cc23)c1 Show InChI InChI=1S/C27H31N5O3/c1-20-9-10-22-13-15-31(24(22)17-20)25-11-12-26(33)32(29-25)19-21-7-6-8-23(18-21)28-27(34)35-16-5-4-14-30(2)3/h6-13,15,17-18H,4-5,14,16,19H2,1-3H3,(H,28,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079540
(CHEMBL3417464)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3cccc(c3)C(F)(F)F)ccc2=O)c1 Show InChI InChI=1S/C25H28F3N5O3/c1-32(2)13-3-4-14-36-24(35)30-20-9-5-7-18(15-20)17-33-23(34)12-11-22(31-33)29-21-10-6-8-19(16-21)25(26,27)28/h5-12,15-16H,3-4,13-14,17H2,1-2H3,(H,29,31)(H,30,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079572
(CHEMBL3417496)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3c(F)cccc23)c1 Show InChI InChI=1S/C26H28FN5O3/c1-30(2)14-3-4-16-35-26(34)28-20-8-5-7-19(17-20)18-32-25(33)12-11-24(29-32)31-15-13-21-22(27)9-6-10-23(21)31/h5-13,15,17H,3-4,14,16,18H2,1-2H3,(H,28,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079549
(CHEMBL3417473)Show SMILES CN(C)CCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C24H24FN5O3/c1-28(2)12-13-33-24(32)26-20-5-3-4-17(14-20)16-30-23(31)9-8-22(27-30)29-11-10-18-6-7-19(25)15-21(18)29/h3-11,14-15H,12-13,16H2,1-2H3,(H,26,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079546
(CHEMBL3417470)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3cc(F)cc(F)c3)ccc2=O)c1 Show InChI InChI=1S/C24H27F2N5O3/c1-30(2)10-3-4-11-34-24(33)28-20-7-5-6-17(12-20)16-31-23(32)9-8-22(29-31)27-21-14-18(25)13-19(26)15-21/h5-9,12-15H,3-4,10-11,16H2,1-2H3,(H,27,29)(H,28,33) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079539
(CHEMBL3417461)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3cccc(C)c3)ccc2=O)c1 Show InChI InChI=1S/C25H31N5O3/c1-19-8-6-10-21(16-19)26-23-12-13-24(31)30(28-23)18-20-9-7-11-22(17-20)27-25(32)33-15-5-4-14-29(2)3/h6-13,16-17H,4-5,14-15,18H2,1-3H3,(H,26,28)(H,27,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079545
(CHEMBL3417469)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3cccc(Cl)c3)ccc2=O)c1 Show InChI InChI=1S/C24H28ClN5O3/c1-29(2)13-3-4-14-33-24(32)27-20-9-5-7-18(15-20)17-30-23(31)12-11-22(28-30)26-21-10-6-8-19(25)16-21/h5-12,15-16H,3-4,13-14,17H2,1-2H3,(H,26,28)(H,27,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079573
(CHEMBL3417497)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3cc(F)ccc23)c1 Show InChI InChI=1S/C26H28FN5O3/c1-30(2)13-3-4-15-35-26(34)28-22-7-5-6-19(16-22)18-32-25(33)11-10-24(29-32)31-14-12-20-17-21(27)8-9-23(20)31/h5-12,14,16-17H,3-4,13,15,18H2,1-2H3,(H,28,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079537
(CHEMBL3417459)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3ccccc3)ccc2=O)c1 Show InChI InChI=1S/C24H29N5O3/c1-28(2)15-6-7-16-32-24(31)26-21-12-8-9-19(17-21)18-29-23(30)14-13-22(27-29)25-20-10-4-3-5-11-20/h3-5,8-14,17H,6-7,15-16,18H2,1-2H3,(H,25,27)(H,26,31) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079547
(CHEMBL3417471)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccccc23)c1 Show InChI InChI=1S/C26H29N5O3/c1-29(2)15-5-6-17-34-26(33)27-22-10-7-8-20(18-22)19-31-25(32)13-12-24(28-31)30-16-14-21-9-3-4-11-23(21)30/h3-4,7-14,16,18H,5-6,15,17,19H2,1-2H3,(H,27,33) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079570
(CHEMBL3417494)Show SMILES COc1ccc2ccn(-c3ccc(=O)n(Cc4cccc(NC(=O)OCCCCN(C)C)c4)n3)c2c1 Show InChI InChI=1S/C27H31N5O4/c1-30(2)14-4-5-16-36-27(34)28-22-8-6-7-20(17-22)19-32-26(33)12-11-25(29-32)31-15-13-21-9-10-23(35-3)18-24(21)31/h6-13,15,17-18H,4-5,14,16,19H2,1-3H3,(H,28,34) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 583 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079544
(CHEMBL3417468)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3ccc(F)cc3)ccc2=O)c1 Show InChI InChI=1S/C24H28FN5O3/c1-29(2)14-3-4-15-33-24(32)27-21-7-5-6-18(16-21)17-30-23(31)13-12-22(28-30)26-20-10-8-19(25)9-11-20/h5-13,16H,3-4,14-15,17H2,1-2H3,(H,26,28)(H,27,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALK (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of EGFR T790M/L858R mutant (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of FGFR1 (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of IGF1R (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-4
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ERBB4 (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Macrophage-stimulating protein receptor
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of RON (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of EGFR (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Ephrin type-A receptor 2
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of EPHA2 (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of FLT1 (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079538
(CHEMBL3417460)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3ccccc3C)ccc2=O)c1 Show InChI InChI=1S/C25H31N5O3/c1-19-9-4-5-12-22(19)27-23-13-14-24(31)30(28-23)18-20-10-8-11-21(17-20)26-25(32)33-16-7-6-15-29(2)3/h4-5,8-14,17H,6-7,15-16,18H2,1-3H3,(H,26,32)(H,27,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of TYRO3 (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of AXL (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50079565
(CHEMBL3417489)Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(CCOc4ccnc5cc(OCCCN6CCOCC6)ccc45)n3)c2c1 Show InChI InChI=1S/C30H30FN5O4/c31-23-3-2-22-9-12-35(27(22)20-23)29-6-7-30(37)36(33-29)15-19-40-28-8-10-32-26-21-24(4-5-25(26)28)39-16-1-11-34-13-17-38-18-14-34/h2-10,12,20-21H,1,11,13-19H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRbeta (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079541
(CHEMBL3417465)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3ccc(cc3)C(F)(F)F)ccc2=O)c1 Show InChI InChI=1S/C25H28F3N5O3/c1-32(2)14-3-4-15-36-24(35)30-21-7-5-6-18(16-21)17-33-23(34)13-12-22(31-33)29-20-10-8-19(9-11-20)25(26,27)28/h5-13,16H,3-4,14-15,17H2,1-2H3,(H,29,31)(H,30,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079542
(CHEMBL3417466)Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3ccccc3F)ccc2=O)c1 Show InChI InChI=1S/C24H28FN5O3/c1-29(2)14-5-6-15-33-24(32)26-19-9-7-8-18(16-19)17-30-23(31)13-12-22(28-30)27-21-11-4-3-10-20(21)25/h3-4,7-13,16H,5-6,14-15,17H2,1-2H3,(H,26,32)(H,27,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079553
(CHEMBL3417477)Show SMILES CCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3ccc(F)cc23)c1 Show InChI InChI=1S/C22H19FN4O3/c1-2-30-22(29)24-18-5-3-4-15(12-18)14-27-21(28)9-8-20(25-27)26-11-10-16-6-7-17(23)13-19(16)26/h3-13H,2,14H2,1H3,(H,24,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079568
(CHEMBL3417492)Show SMILES CN(C)CCCCOC(=O)Nc1ccccc1Cn1nc(Nc2ccccc2C)ccc1=O Show InChI InChI=1S/C25H31N5O3/c1-19-10-4-6-12-21(19)26-23-14-15-24(31)30(28-23)18-20-11-5-7-13-22(20)27-25(32)33-17-9-8-16-29(2)3/h4-7,10-15H,8-9,16-18H2,1-3H3,(H,26,28)(H,27,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079567
(CHEMBL3417491)Show SMILES CN(C)CCCCOC(=O)Nc1ccc(Cn2nc(Nc3ccccc3C)ccc2=O)cc1 Show InChI InChI=1S/C25H31N5O3/c1-19-8-4-5-9-22(19)27-23-14-15-24(31)30(28-23)18-20-10-12-21(13-11-20)26-25(32)33-17-7-6-16-29(2)3/h4-5,8-15H,6-7,16-18H2,1-3H3,(H,26,32)(H,27,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50079536
(CHEMBL3417490)Show InChI InChI=1S/C17H16N4O/c18-14-8-6-13(7-9-14)12-21-17(22)11-10-16(20-21)19-15-4-2-1-3-5-15/h1-11H,12,18H2,(H,19,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) |
Eur J Med Chem 95: 302-12 (2015)
Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4 |
More data for this
Ligand-Target Pair | |
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