Compile Data Set for Download or QSAR

Found 1594 hits with Last Name = 'parker' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM50579244 (Avoralstat | BCX-4161) Show SMILES COc1cc(c(cc1C=C)C(=O)Nc1ccc(cc1)C(N)=N)-c1ccc(nc1C(O)=O)C(=O)NCC1CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of purified human plasma kallikrein assessed as inhibition constant using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by m...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00511 BindingDB Entry DOI: 10.7270/Q29C7288
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335260 (CHEMBL1651226 | N,N-dihexyl-2-(1-methyl-2-phenyl-1...) Show SMILES CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 Show InChI InChI=1S/C29H38N2O2/c1-4-6-8-15-21-31(22-16-9-7-5-2)29(33)28(32)26-24-19-13-14-20-25(24)30(3)27(26)23-17-11-10-12-18-23/h10-14,17-20H,4-9,15-16,21-22H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.299	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335259 (CHEMBL1651225 | N,N-dibutyl-2-(1-methyl-2-phenyl-1...) Show SMILES CCCCN(CCCC)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 Show InChI InChI=1S/C25H30N2O2/c1-4-6-17-27(18-7-5-2)25(29)24(28)22-20-15-11-12-16-21(20)26(3)23(22)19-13-9-8-10-14-19/h8-16H,4-7,17-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM22038 (2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexyl-2...) Show SMILES CCCCCCN(CCCCCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C28H35FN2O2/c1-3-5-7-11-19-31(20-12-8-6-4-2)28(33)27(32)25-23-13-9-10-14-24(23)30-26(25)21-15-17-22(29)18-16-21/h9-10,13-18,30H,3-8,11-12,19-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM416926 ((+)-1-(3-(aminomethyl)phenyl)-N-(5-((3-cyanophenyl...) Show SMILES NCc1cccc(c1)-n1nc(cc1C(=O)Nc1cc(ccc1F)C(NCC1CC1)c1cccc(c1)C#N)C(F)(F)F Show InChI InChI=1S/C30H26F4N6O/c31-24-10-9-22(28(37-17-18-7-8-18)21-5-1-3-19(11-21)15-35)13-25(24)38-29(41)26-14-27(30(32,33)34)39-40(26)23-6-2-4-20(12-23)16-36/h1-6,9-14,18,28,37H,7-8,16-17,36H2,(H,38,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of purified human plasma kallikrein assessed as inhibition constant using H-D-Pro-Phe-Arg-pNA.2HCl as substrate measured after 3 mins by m...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00511 BindingDB Entry DOI: 10.7270/Q29C7288
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50060095 (2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...) Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H22Cl3N3O/c1-3-9-26(10-4-2)19(28)12-18-20(14-5-7-15(22)8-6-14)25-21-17(24)11-16(23)13-27(18)21/h5-8,11,13H,3-4,9-10,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335268 (2-(2-(4-fluorophenyl)-1-methyl-1H-indol-3-yl)-N,N-...) Show SMILES CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccc(F)cc2)n(C)c2ccccc12 Show InChI InChI=1S/C29H37FN2O2/c1-4-6-8-12-20-32(21-13-9-7-5-2)29(34)28(33)26-24-14-10-11-15-25(24)31(3)27(26)22-16-18-23(30)19-17-22/h10-11,14-19H,4-9,12-13,20-21H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50143220 (CHEMBL294625 | N,N-Dihexyl-2-oxo-2-(2-phenyl-1H-in...) Show SMILES CCCCCCN(CCCCCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C28H36N2O2/c1-3-5-7-14-20-30(21-15-8-6-4-2)28(32)27(31)25-23-18-12-13-19-24(23)29-26(25)22-16-10-9-11-17-22/h9-13,16-19,29H,3-8,14-15,20-21H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM50335270 (2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c(-c2ccc(cc2)[N+]([O-])=O)n(C)c2ccccc12 Show InChI InChI=1S/C23H25N3O4/c1-4-14-25(15-5-2)23(28)22(27)20-18-8-6-7-9-19(18)24(3)21(20)16-10-12-17(13-11-16)26(29)30/h6-13H,4-5,14-15H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from high affinity binding site of TSPO in human brain membrane homogenate by scintillation counting				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335257 (CHEMBL1651223 | N-benzyl-2-(2-(4-fluorophenyl)-1H-...) Show SMILES CN(Cc1ccccc1)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C24H19FN2O2/c1-27(15-16-7-3-2-4-8-16)24(29)23(28)21-19-9-5-6-10-20(19)26-22(21)17-11-13-18(25)14-12-17/h2-14,26H,15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM50335270 (2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c(-c2ccc(cc2)[N+]([O-])=O)n(C)c2ccccc12 Show InChI InChI=1S/C23H25N3O4/c1-4-14-25(15-5-2)23(28)22(27)20-18-8-6-7-9-19(18)24(3)21(20)16-10-12-17(13-11-16)26(29)30/h6-13H,4-5,14-15H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from mixed affinity binding site of TSPO in human brain membrane homogenate by scintillation counting				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Rattus norvegicus (rat))	BDBM50338518 (1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CC(F)(F)CCC1=O)c1ncnc(n1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C16H21F4N7O/c17-15(18)2-1-12(28)27(8-15)11-6-26(5-10(11)21)14-23-9-22-13(24-14)25-4-3-16(19,20)7-25/h9-11H,1-8,21H2/t10-,11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of DPP4 in rat plasma				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335262 (CHEMBL1651228 | N-benzyl-N-ethyl-2-(1-methyl-2-phe...) Show SMILES CCN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 Show InChI InChI=1S/C26H24N2O2/c1-3-28(18-19-12-6-4-7-13-19)26(30)25(29)23-21-16-10-11-17-22(21)27(2)24(23)20-14-8-5-9-15-20/h4-17H,3,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50301021 ((+)-dihydrotetrabenzaine | CHEMBL576222 | US110532...) Show SMILES COc1cc2CCN3C[C@@H](CC(C)C)[C@H](O)C[C@@H]3c2cc1OC |r| Show InChI InChI=1S/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3/t14-,16-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-DHTBZ binding to VMAT2 from rat forebrain membranes				J Med Chem 63: 3834-3867 (2020) Article DOI: 10.1021/acs.jmedchem.9b01237 BindingDB Entry DOI: 10.7270/Q26113PD
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50143244 (2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-2-oxo-N,N-di...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN2O2/c1-3-13-25(14-4-2)22(27)21(26)19-17-7-5-6-8-18(17)24-20(19)15-9-11-16(23)12-10-15/h5-12,24H,3-4,13-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335270 (2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c(-c2ccc(cc2)[N+]([O-])=O)n(C)c2ccccc12 Show InChI InChI=1S/C23H25N3O4/c1-4-14-25(15-5-2)23(28)22(27)20-18-8-6-7-9-19(18)24(3)21(20)16-10-12-17(13-11-16)26(29)30/h6-13H,4-5,14-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335269 (CHEMBL1651235 | N-benzyl-2-(2-(4-fluorophenyl)-1-m...) Show SMILES CN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(F)cc2)n(C)c2ccccc12 Show InChI InChI=1S/C25H21FN2O2/c1-27(16-17-8-4-3-5-9-17)25(30)24(29)22-20-10-6-7-11-21(20)28(2)23(22)18-12-14-19(26)15-13-18/h3-15H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50143236 (CHEMBL431938 | N,N-Dibutyl-2-oxo-2-(2-phenyl-1H-in...) Show SMILES CCCCN(CCCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C24H28N2O2/c1-3-5-16-26(17-6-4-2)24(28)23(27)21-19-14-10-11-15-20(19)25-22(21)18-12-8-7-9-13-18/h7-15,25H,3-6,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM22032 (1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...) Show SMILES CCC(C)N(C)C(=O)c1cc2ccccc2c(n1)-c1ccccc1Cl Show InChI InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Translocator protein (Homo sapiens (Human))	BDBM50335270 (2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c(-c2ccc(cc2)[N+]([O-])=O)n(C)c2ccccc12 Show InChI InChI=1S/C23H25N3O4/c1-4-14-25(15-5-2)23(28)22(27)20-18-8-6-7-9-19(18)24(3)21(20)16-10-12-17(13-11-16)26(29)30/h6-13H,4-5,14-15H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from low affinity binding site of TSPO in human brain membrane homogenate by scintillation counting				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335256 (CHEMBL1651222 | N-benzyl-N-methyl-2-oxo-2-(2-pheny...) Show SMILES CN(Cc1ccccc1)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C24H20N2O2/c1-26(16-17-10-4-2-5-11-17)24(28)23(27)21-19-14-8-9-15-20(19)25-22(21)18-12-6-3-7-13-18/h2-15,25H,16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50143223 (2-Oxo-2-(2-phenyl-1H-indol-3-yl)-N,N-dipropyl-acet...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C22H24N2O2/c1-3-14-24(15-4-2)22(26)21(25)19-17-12-8-9-13-18(17)23-20(19)16-10-6-5-7-11-16/h5-13,23H,3-4,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50338518 (1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CC(F)(F)CCC1=O)c1ncnc(n1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C16H21F4N7O/c17-15(18)2-1-12(28)27(8-15)11-6-26(5-10(11)21)14-23-9-22-13(24-14)25-4-3-16(19,20)7-25/h9-11H,1-8,21H2/t10-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335258 (2-(1-methyl-2-phenyl-1H-indol-3-yl)-2-oxo-N,N-dipr...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 Show InChI InChI=1S/C23H26N2O2/c1-4-15-25(16-5-2)23(27)22(26)20-18-13-9-10-14-19(18)24(3)21(20)17-11-7-6-8-12-17/h6-14H,4-5,15-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335267 (2-(2-(4-fluorophenyl)-1-methyl-1H-indol-3-yl)-2-ox...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c(-c2ccc(F)cc2)n(C)c2ccccc12 Show InChI InChI=1S/C23H25FN2O2/c1-4-14-26(15-5-2)23(28)22(27)20-18-8-6-7-9-19(18)25(3)21(20)16-10-12-17(24)13-11-16/h6-13H,4-5,14-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335265 (CHEMBL1651231 | N-benzyl-N-methyl-2-(1-methyl-2-ph...) Show SMILES CN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 Show InChI InChI=1S/C25H22N2O2/c1-26(17-18-11-5-3-6-12-18)25(29)24(28)22-20-15-9-10-16-21(20)27(2)23(22)19-13-7-4-8-14-19/h3-16H,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM22040 (4 -chlorodiazepam | 4' Cl-diazepam | 7-chloro-...) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccc(Cl)cc1 |c:10| Show InChI InChI=1S/C16H12Cl2N2O/c1-20-14-7-6-12(18)8-13(14)16(19-9-15(20)21)10-2-4-11(17)5-3-10/h2-8H,9H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335266 (2-(5-fluoro-1-methyl-2-phenyl-1H-indol-3-yl)-2-oxo...) Show SMILES CCCN(CCC)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccc(F)cc12 Show InChI InChI=1S/C23H25FN2O2/c1-4-13-26(14-5-2)23(28)22(27)20-18-15-17(24)11-12-19(18)25(3)21(20)16-9-7-6-8-10-16/h6-12,15H,4-5,13-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50140541 ((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C12H20F2N2O/c13-12(14)6-7-16(8-12)11(17)10(15)9-4-2-1-3-5-9/h9-10H,1-8,15H2/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335264 (CHEMBL1651230 | N-methyl-2-(1-methyl-2-phenyl-1H-i...) Show SMILES CCCCCN(C)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 Show InChI InChI=1S/C23H26N2O2/c1-4-5-11-16-24(2)23(27)22(26)20-18-14-9-10-15-19(18)25(3)21(20)17-12-7-6-8-13-17/h6-10,12-15H,4-5,11,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50140527 ((S)-2-Amino-2-cyclohexyl-1-((S)-3-fluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC[C@H](F)C1 Show InChI InChI=1S/C12H21FN2O/c13-10-6-7-15(8-10)12(16)11(14)9-4-2-1-3-5-9/h9-11H,1-8,14H2/t10-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335261 (CHEMBL1651227 | N-butyl-N-ethyl-2-(1-methyl-2-phen...) Show SMILES CCCCN(CC)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 Show InChI InChI=1S/C23H26N2O2/c1-4-6-16-25(5-2)23(27)22(26)20-18-14-10-11-15-19(18)24(3)21(20)17-12-8-7-9-13-17/h7-15H,4-6,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172141 ((S)-2-Amino-2-cyclohexyl-1-(3,4-difluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC(F)C(F)C1 Show InChI InChI=1S/C12H20F2N2O/c13-9-6-16(7-10(9)14)12(17)11(15)8-4-2-1-3-5-8/h8-11H,1-7,15H2/t9?,10?,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV calculated from IC50 from standard dose inhibition curve using cheng-Prussoff equation; range=61+/...				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172144 ((S)-2-Amino-2-cyclohexyl-1-(2,3,4,5-tetrafluoro-py...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1C(F)C(F)C(F)C1F Show InChI InChI=1S/C12H18F4N2O/c13-7-8(14)11(16)18(10(7)15)12(19)9(17)6-4-2-1-3-5-6/h6-11H,1-5,17H2/t7?,8?,9-,10?,11?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172143 ((S)-2-Amino-2-cyclohexyl-1-(3-fluoro-azetidin-1-yl...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC(F)C1 Show InChI InChI=1S/C11H19FN2O/c12-9-6-14(7-9)11(15)10(13)8-4-2-1-3-5-8/h8-10H,1-7,13H2/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172139 ((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-azetidin-...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC(F)(F)C1 Show InChI InChI=1S/C11H18F2N2O/c12-11(13)6-15(7-11)10(16)9(14)8-4-2-1-3-5-8/h8-9H,1-7,14H2/t9-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM12191 ((2S)-2-amino-2-cyclohexyl-1-(pyrrolidin-1-yl)ethan...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCCC1 |r| Show InChI InChI=1S/C12H22N2O/c13-11(10-6-2-1-3-7-10)12(15)14-8-4-5-9-14/h10-11H,1-9,13H2/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50140539 ((S)-2-Amino-2-cyclohexyl-1-((R)-3-fluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC[C@@H](F)C1 Show InChI InChI=1S/C12H21FN2O/c13-10-6-7-15(8-10)12(16)11(14)9-4-2-1-3-5-9/h9-11H,1-8,14H2/t10-,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50335263 (CHEMBL1651229 | N-butyl-N-methyl-2-(1-methyl-2-phe...) Show SMILES CCCCN(C)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 Show InChI InChI=1S/C22H24N2O2/c1-4-5-15-23(2)22(26)21(25)19-17-13-9-10-14-18(17)24(3)20(19)16-11-7-6-8-12-16/h6-14H,4-5,15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membrane				J Med Chem 54: 366-73 (2011) Article DOI: 10.1021/jm101230g BindingDB Entry DOI: 10.7270/Q2ZC83T4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172145 ((S)-2-Amino-2-cyclohexyl-1-((3R,4R)-3,4-difluoro-p...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1C[C@@H](F)[C@H](F)C1 Show InChI InChI=1S/C12H20F2N2O/c13-9-6-16(7-10(9)14)12(17)11(15)8-4-2-1-3-5-8/h8-11H,1-7,15H2/t9-,10-,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	504	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172140 ((S)-2-Amino-2-cyclohexyl-1-((3S,4S)-3,4-difluoro-p...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1C[C@H](F)[C@@H](F)C1 Show InChI InChI=1S/C12H20F2N2O/c13-9-6-16(7-10(9)14)12(17)11(15)8-4-2-1-3-5-8/h8-11H,1-7,15H2/t9-,10-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172142 ((S)-2-Amino-1-azetidin-1-yl-2-cyclohexyl-ethanone ...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC1 Show InChI InChI=1S/C11H20N2O/c12-10(9-5-2-1-3-6-9)11(14)13-7-4-8-13/h9-10H,1-8,12H2/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Homo sapiens (Human))	BDBM50338518 (1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CC(F)(F)CCC1=O)c1ncnc(n1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C16H21F4N7O/c17-15(18)2-1-12(28)27(8-15)11-6-26(5-10(11)21)14-23-9-22-13(24-14)25-4-3-16(19,20)7-25/h9-11H,1-8,21H2/t10-,11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of FAP				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50338518 (1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CC(F)(F)CCC1=O)c1ncnc(n1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C16H21F4N7O/c17-15(18)2-1-12(28)27(8-15)11-6-26(5-10(11)21)14-23-9-22-13(24-14)25-4-3-16(19,20)7-25/h9-11H,1-8,21H2/t10-,11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of DPP2				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 3 (Homo sapiens (Human))	BDBM50338518 (1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CC(F)(F)CCC1=O)c1ncnc(n1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C16H21F4N7O/c17-15(18)2-1-12(28)27(8-15)11-6-26(5-10(11)21)14-23-9-22-13(24-14)25-4-3-16(19,20)7-25/h9-11H,1-8,21H2/t10-,11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of DPP3				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50338518 (1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CC(F)(F)CCC1=O)c1ncnc(n1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C16H21F4N7O/c17-15(18)2-1-12(28)27(8-15)11-6-26(5-10(11)21)14-23-9-22-13(24-14)25-4-3-16(19,20)7-25/h9-11H,1-8,21H2/t10-,11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of POP				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50338518 (1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CC(F)(F)CCC1=O)c1ncnc(n1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C16H21F4N7O/c17-15(18)2-1-12(28)27(8-15)11-6-26(5-10(11)21)14-23-9-22-13(24-14)25-4-3-16(19,20)7-25/h9-11H,1-8,21H2/t10-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of DPP9				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair
Oxidized purine nucleoside triphosphate hydrolase (Homo sapiens (Human))	BDBM50152144 (CHEMBL3781661) Show SMILES Cc1cnc(N)nc1OCC(C)(C)C Show InChI InChI=1S/C10H17N3O/c1-7-5-12-9(11)13-8(7)14-6-10(2,3)4/h5H,6H2,1-4H3,(H2,11,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
MD Anderson Cancer Center Curated by ChEMBL					Assay Description Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assay				Bioorg Med Chem Lett 26: 1503-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.026 BindingDB Entry DOI: 10.7270/Q20K2BF6
					More data for this Ligand-Target Pair
Oxidized purine nucleoside triphosphate hydrolase (Homo sapiens (Human))	BDBM50152127 (CHEMBL3780962) Show SMILES CN(CC(C)(C)C)c1nc(N)ncc1C Show InChI InChI=1S/C11H20N4/c1-8-6-13-10(12)14-9(8)15(5)7-11(2,3)4/h6H,7H2,1-5H3,(H2,12,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
MD Anderson Cancer Center Curated by ChEMBL					Assay Description Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assay				Bioorg Med Chem Lett 26: 1503-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.026 BindingDB Entry DOI: 10.7270/Q20K2BF6
					More data for this Ligand-Target Pair
Presenilin-1 (Homo sapiens (Human))	BDBM50483746 (CHEMBL1770758) Show SMILES CCC[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(cn1)C(CC)CC |r| Show InChI InChI=1S/C21H28F2N4O2/c1-4-7-18(25-20(28)10-14-8-15(22)11-16(23)9-14)21(29)26-19-12-27(13-24-19)17(5-2)6-3/h8-9,11-13,17-18H,4-7,10H2,1-3H3,(H,25,28)(H,26,29)/t18-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassay				Bioorg Med Chem Lett 21: 2631-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.117 BindingDB Entry DOI: 10.7270/Q2K64MX1
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1594 total )  |  Next  |  Last  >>

Jump to: