Compile Data Set for Download or QSAR

Found 75 hits with Last Name = 'riggs' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM25680 (4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...) Show SMILES OC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C10H7BrN2O2S/c11-8-5-12-10(16-8)13-7-3-1-6(2-4-7)9(14)15/h1-5H,(H,12,13)(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25683 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-methoxyet...) Show SMILES COCCNC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C13H14BrN3O2S/c1-19-7-6-15-12(18)9-2-4-10(5-3-9)17-13-16-8-11(14)20-13/h2-5,8H,6-7H2,1H3,(H,15,18)(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25681 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzam...) Show SMILES CNC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C11H10BrN3OS/c1-13-10(16)7-2-4-8(5-3-7)15-11-14-6-9(12)17-11/h2-6H,1H3,(H,13,16)(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25684 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(1-methoxypr...) Show SMILES COCC(C)NC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C14H16BrN3O2S/c1-9(8-20-2)17-13(19)10-3-5-11(6-4-10)18-14-16-7-12(15)21-14/h3-7,9H,8H2,1-2H3,(H,16,18)(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25678 (N-{4-[(5-bromo-1,3-thiazol-2-yl)amino]phenyl}aceta...) Show SMILES CC(=O)Nc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C11H10BrN3OS/c1-7(16)14-8-2-4-9(5-3-8)15-11-13-6-10(12)17-11/h2-6H,1H3,(H,13,15)(H,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM25658 (5-bromo-N-(4-fluorophenyl)-1,3-thiazol-2-amine | a...) Show SMILES Fc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C9H6BrFN2S/c10-8-5-12-9(14-8)13-7-3-1-6(11)2-4-7/h1-5H,(H,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25658 (5-bromo-N-(4-fluorophenyl)-1,3-thiazol-2-amine | a...) Show SMILES Fc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C9H6BrFN2S/c10-8-5-12-9(14-8)13-7-3-1-6(11)2-4-7/h1-5H,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM25681 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzam...) Show SMILES CNC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C11H10BrN3OS/c1-13-10(16)7-2-4-8(5-3-7)15-11-14-6-9(12)17-11/h2-6H,1H3,(H,13,16)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25697 (3-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...) Show SMILES OC(=O)c1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C10H7BrN2O2S/c11-8-5-12-10(16-8)13-7-3-1-2-6(4-7)9(14)15/h1-5H,(H,12,13)(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25694 (5-bromo-N-[3-(methylsulfanyl)phenyl]-1,3-thiazol-2...) Show SMILES CSc1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C10H9BrN2S2/c1-14-8-4-2-3-7(5-8)13-10-12-6-9(11)15-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25660 (N-(4-fluorophenyl)-5-iodo-1,3-thiazol-2-amine | am...) Show SMILES Fc1ccc(Nc2ncc(I)s2)cc1 Show InChI InChI=1S/C9H6FIN2S/c10-6-1-3-7(4-2-6)13-9-12-5-8(11)14-9/h1-5H,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25669 (4-[(5-bromo-1,3-thiazol-2-yl)amino]phenol | aminot...) Show SMILES Oc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C9H7BrN2OS/c10-8-5-11-9(14-8)12-6-1-3-7(13)4-2-6/h1-5,13H,(H,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25676 (1-N-(5-bromo-1,3-thiazol-2-yl)benzene-1,4-diamine ...) Show SMILES Nc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C9H8BrN3S/c10-8-5-12-9(14-8)13-7-3-1-6(11)2-4-7/h1-5H,11H2,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25699 (3-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzam...) Show SMILES CNC(=O)c1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C11H10BrN3OS/c1-13-10(16)7-3-2-4-8(5-7)15-11-14-6-9(12)17-11/h2-6H,1H3,(H,13,16)(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25721 (4-({6-[(5-cyano-1,3-thiazol-2-yl)amino]pyridin-3-y...) Show SMILES CNC(=O)N1CCN(Cc2ccc(Nc3ncc(s3)C#N)nc2)CC1 Show InChI InChI=1S/C16H19N7OS/c1-18-16(24)23-6-4-22(5-7-23)11-12-2-3-14(19-9-12)21-15-20-10-13(8-17)25-15/h2-3,9-10H,4-7,11H2,1H3,(H,18,24)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25673 (5-bromo-N-[4-(pyridin-4-yloxy)phenyl]-1,3-thiazol-...) Show SMILES Brc1cnc(Nc2ccc(Oc3ccncc3)cc2)s1 Show InChI InChI=1S/C14H10BrN3OS/c15-13-9-17-14(20-13)18-10-1-3-11(4-2-10)19-12-5-7-16-8-6-12/h1-9H,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25693 (5-bromo-N-(3-methoxyphenyl)-1,3-thiazol-2-amine | ...) Show SMILES COc1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C10H9BrN2OS/c1-14-8-4-2-3-7(5-8)13-10-12-6-9(11)15-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM25680 (4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...) Show SMILES OC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C10H7BrN2O2S/c11-8-5-12-10(16-8)13-7-3-1-6(2-4-7)9(14)15/h1-5H,(H,12,13)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25685 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-methoxyet...) Show SMILES COCCN(C)C(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C14H16BrN3O2S/c1-18(7-8-20-2)13(19)10-3-5-11(6-4-10)17-14-16-9-12(15)21-14/h3-6,9H,7-8H2,1-2H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25662 (5-bromo-N-phenyl-1,3-thiazol-2-amine | aminothiazo...) Show SMILES Brc1cnc(Nc2ccccc2)s1 Show InChI InChI=1S/C9H7BrN2S/c10-8-6-11-9(13-8)12-7-4-2-1-3-5-7/h1-6H,(H,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25657 (5-chloro-N-(4-fluorophenyl)-1,3-thiazol-2-amine | ...) Show SMILES Fc1ccc(Nc2ncc(Cl)s2)cc1 Show InChI InChI=1S/C9H6ClFN2S/c10-8-5-12-9(14-8)13-7-3-1-6(11)2-4-7/h1-5H,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25691 (5-bromo-N-(3-methylphenyl)-1,3-thiazol-2-amine | a...) Show SMILES Cc1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C10H9BrN2S/c1-7-3-2-4-8(5-7)13-10-12-6-9(11)14-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25698 (3-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-methoxyet...) Show SMILES COCCNC(=O)c1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C13H14BrN3O2S/c1-19-6-5-15-12(18)9-3-2-4-10(7-9)17-13-16-8-11(14)20-13/h2-4,7-8H,5-6H2,1H3,(H,15,18)(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25720 (2-{[5-(morpholin-4-ylmethyl)pyridin-2-yl]amino}-1,...) Show SMILES N#Cc1cnc(Nc2ccc(CN3CCOCC3)cn2)s1 Show InChI InChI=1S/C14H15N5OS/c15-7-12-9-17-14(21-12)18-13-2-1-11(8-16-13)10-19-3-5-20-6-4-19/h1-2,8-9H,3-6,10H2,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25672 (5-bromo-N-(4-phenoxyphenyl)-1,3-thiazol-2-amine | ...) Show SMILES Brc1cnc(Nc2ccc(Oc3ccccc3)cc2)s1 Show InChI InChI=1S/C15H11BrN2OS/c16-14-10-17-15(20-14)18-11-6-8-13(9-7-11)19-12-4-2-1-3-5-12/h1-10H,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25682 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-hydroxyet...) Show SMILES OCCNC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C12H12BrN3O2S/c13-10-7-15-12(19-10)16-9-3-1-8(2-4-9)11(18)14-5-6-17/h1-4,7,17H,5-6H2,(H,14,18)(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25695 (3-[(5-bromo-1,3-thiazol-2-yl)amino]benzonitrile | ...) Show SMILES Brc1cnc(Nc2cccc(c2)C#N)s1 Show InChI InChI=1S/C10H6BrN3S/c11-9-6-13-10(15-9)14-8-3-1-2-7(4-8)5-12/h1-4,6H,(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25674 (1-{4-[(5-bromo-1,3-thiazol-2-yl)amino]phenyl}ethan...) Show SMILES CC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C11H9BrN2OS/c1-7(15)8-2-4-9(5-3-8)14-11-13-6-10(12)16-11/h2-6H,1H3,(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25670 (5-bromo-N-(4-methoxyphenyl)-1,3-thiazol-2-amine | ...) Show SMILES COc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C10H9BrN2OS/c1-14-8-4-2-7(3-5-8)13-10-12-6-9(11)15-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM5359 (5-bromo-N-(pyridin-2-yl)-1,3-thiazol-2-amine | ACS...) Show SMILES Brc1cnc(Nc2ccccn2)s1 Show InChI InChI=1S/C8H6BrN3S/c9-6-5-11-8(13-6)12-7-3-1-2-4-10-7/h1-5H,(H,10,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25668 (4-[(5-bromo-1,3-thiazol-2-yl)amino]benzonitrile | ...) Show SMILES Brc1cnc(Nc2ccc(cc2)C#N)s1 Show InChI InChI=1S/C10H6BrN3S/c11-9-6-13-10(15-9)14-8-3-1-7(5-12)2-4-8/h1-4,6H,(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25696 (aminothiazole analogue, 40 | ethyl 3-[(5-bromo-1,3...) Show SMILES CCOC(=O)c1cccc(Nc2ncc(Br)s2)c1 Show InChI InChI=1S/C12H11BrN2O2S/c1-2-17-11(16)8-4-3-5-9(6-8)15-12-14-7-10(13)18-12/h3-7H,2H2,1H3,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25688 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(morpholi...) Show SMILES Brc1cnc(Nc2ccc(cc2)C(=O)NCCN2CCOCC2)s1 Show InChI InChI=1S/C16H19BrN4O2S/c17-14-11-19-16(24-14)20-13-3-1-12(2-4-13)15(22)18-5-6-21-7-9-23-10-8-21/h1-4,11H,5-10H2,(H,18,22)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25667 (5-bromo-N-[4-(trifluoromethyl)phenyl]-1,3-thiazol-...) Show SMILES FC(F)(F)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C10H6BrF3N2S/c11-8-5-15-9(17-8)16-7-3-1-6(2-4-7)10(12,13)14/h1-5H,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM5362 (2-(pyridin-2-ylamino)-1,3-thiazole-5-carbonitrile ...) Show SMILES N#Cc1cnc(Nc2ccccn2)s1 Show InChI InChI=1S/C9H6N4S/c10-5-7-6-12-9(14-7)13-8-3-1-2-4-11-8/h1-4,6H,(H,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25703 (5-bromo-N-(2-methoxyphenyl)-1,3-thiazol-2-amine | ...) Show SMILES COc1ccccc1Nc1ncc(Br)s1 Show InChI InChI=1S/C10H9BrN2OS/c1-14-8-5-3-2-4-7(8)13-10-12-6-9(11)15-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25666 (5-bromo-N-(4-methylphenyl)-1,3-thiazol-2-amine | a...) Show SMILES Cc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C10H9BrN2S/c1-7-2-4-8(5-3-7)13-10-12-6-9(11)14-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25664 (5-bromo-N-(4-bromophenyl)-1,3-thiazol-2-amine | am...) Show SMILES Brc1cnc(Nc2ccc(Br)cc2)s1 Show InChI InChI=1S/C9H6Br2N2S/c10-6-1-3-7(4-2-6)13-9-12-5-8(11)14-9/h1-5H,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25701 (5-bromo-N-(2-methylphenyl)-1,3-thiazol-2-amine | a...) Show SMILES Cc1ccccc1Nc1ncc(Br)s1 Show InChI InChI=1S/C10H9BrN2S/c1-7-4-2-3-5-8(7)13-10-12-6-9(11)14-10/h2-6H,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25663 (5-bromo-N-(4-chlorophenyl)-1,3-thiazol-2-amine | a...) Show SMILES Clc1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C9H6BrClN2S/c10-8-5-12-9(14-8)13-7-3-1-6(11)2-4-7/h1-5H,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.0	22
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25717 (5-bromo-N-(pyridin-3-yl)-1,3-thiazol-2-amine | ami...) Show SMILES Brc1cnc(Nc2cccnc2)s1 Show InChI InChI=1S/C8H6BrN3S/c9-7-5-11-8(13-7)12-6-2-1-3-10-4-6/h1-5H,(H,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25722 (2-({5-[(4-methylpiperazin-1-yl)methyl]pyridin-2-yl...) Show SMILES CN1CCN(Cc2ccc(Nc3ncc(s3)C#N)nc2)CC1 Show InChI InChI=1S/C15H18N6S/c1-20-4-6-21(7-5-20)11-12-2-3-14(17-9-12)19-15-18-10-13(8-16)22-15/h2-3,9-10H,4-7,11H2,1H3,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM25681 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzam...) Show SMILES CNC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C11H10BrN3OS/c1-13-10(16)7-2-4-8(5-3-7)15-11-14-6-9(12)17-11/h2-6H,1H3,(H,13,16)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25723 (2-({5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(s3)C#N)nc2)CC1 Show InChI InChI=1S/C16H20N6S/c1-2-21-5-7-22(8-6-21)12-13-3-4-15(18-10-13)20-16-19-11-14(9-17)23-16/h3-4,10-11H,2,5-8,12H2,1H3,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25687 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(diethyla...) Show SMILES CCN(CC)CCNC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C16H21BrN4OS/c1-3-21(4-2)10-9-18-15(22)12-5-7-13(8-6-12)20-16-19-11-14(17)23-16/h5-8,11H,3-4,9-10H2,1-2H3,(H,18,22)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25715 (5-bromo-N-(naphthalen-1-yl)-1,3-thiazol-2-amine | ...) Show SMILES Brc1cnc(Nc2cccc3ccccc23)s1 Show InChI InChI=1S/C13H9BrN2S/c14-12-8-15-13(17-12)16-11-7-3-5-9-4-1-2-6-10(9)11/h1-8H,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25686 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(dimethyl...) Show SMILES CN(C)CCNC(=O)c1ccc(Nc2ncc(Br)s2)cc1 Show InChI InChI=1S/C14H17BrN4OS/c1-19(2)8-7-16-13(20)10-3-5-11(6-4-10)18-14-17-9-12(15)21-14/h3-6,9H,7-8H2,1-2H3,(H,16,20)(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25689 (4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(pyrrolid...) Show SMILES Brc1cnc(Nc2ccc(cc2)C(=O)NCCN2CCCC2)s1 Show InChI InChI=1S/C16H19BrN4OS/c17-14-11-19-16(23-14)20-13-5-3-12(4-6-13)15(22)18-7-10-21-8-1-2-9-21/h3-6,11H,1-2,7-10H2,(H,18,22)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25724 (2-[(5-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}py...) Show SMILES OCCN1CCN(Cc2ccc(Nc3ncc(s3)C#N)nc2)CC1 Show InChI InChI=1S/C16H20N6OS/c17-9-14-11-19-16(24-14)20-15-2-1-13(10-18-15)12-22-5-3-21(4-6-22)7-8-23/h1-2,10-11,23H,3-8,12H2,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM25712 (N-(5-bromo-1,3-thiazol-2-yl)benzamide | aminothiaz...) Show SMILES Brc1cnc(NC(=O)c2ccccc2)s1 Show InChI InChI=1S/C10H7BrN2OS/c11-8-6-12-10(15-8)13-9(14)7-4-2-1-3-5-7/h1-6H,(H,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis					Assay Description The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...				ACS Chem Biol 3: 180-92 (2008) Article DOI: 10.1021/cb700200w BindingDB Entry DOI: 10.7270/Q2HX1B03
					More data for this Ligand-Target Pair

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