Compile Data Set for Download or QSAR

Found 462 hits with Last Name = 'saito' and Initial = 'rd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270592 ((S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C31H31F2N9O/c1-30(2,3)16-35-27-23-13-19(12-18(14-34)25(23)36-17-37-27)38-26(24-15-42(40-39-24)31(9-10-31)29(32)33)21-6-5-7-22-20(21)8-11-41(4)28(22)43/h5-8,11-13,15,17,26,29,38H,9-10,16H2,1-4H3,(H,35,36,37)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270592 ((S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C31H31F2N9O/c1-30(2,3)16-35-27-23-13-19(12-18(14-34)25(23)36-17-37-27)38-26(24-15-42(40-39-24)31(9-10-31)29(32)33)21-6-5-7-22-20(21)8-11-41(4)28(22)43/h5-8,11-13,15,17,26,29,38H,9-10,16H2,1-4H3,(H,35,36,37)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270591 ((S)-3-(((8-chloro-4- (neopentylamino) quinazolin-6...) Show SMILES Cc1c(cccc1[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F)C#N |r| Show InChI InChI=1S/C28H29ClF2N8/c1-16-17(12-32)6-5-7-19(16)24(22-13-39(38-37-22)28(8-9-28)26(30)31)36-18-10-20-23(21(29)11-18)34-15-35-25(20)33-14-27(2,3)4/h5-7,10-11,13,15,24,26,36H,8-9,14H2,1-4H3,(H,33,34,35)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270591 ((S)-3-(((8-chloro-4- (neopentylamino) quinazolin-6...) Show SMILES Cc1c(cccc1[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F)C#N |r| Show InChI InChI=1S/C28H29ClF2N8/c1-16-17(12-32)6-5-7-19(16)24(22-13-39(38-37-22)28(8-9-28)26(30)31)36-18-10-20-23(21(29)11-18)34-15-35-25(20)33-14-27(2,3)4/h5-7,10-11,13,15,24,26,36H,8-9,14H2,1-4H3,(H,33,34,35)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270594 ((S)-5-((1- (bicyclo[1.1.1]pentan- 1-yl)-1H-1,2,3- ...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C12CC(C1)C2 |r| Show InChI InChI=1S/C31H33ClN8O/c1-30(2,3)16-33-28-23-10-19(11-24(32)26(23)34-17-35-28)36-27(25-15-40(38-37-25)31-12-18(13-31)14-31)21-6-5-7-22-20(21)8-9-39(4)29(22)41/h5-11,15,17-18,27,36H,12-14,16H2,1-4H3,(H,33,34,35)/t18?,27-,31?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270590 ((S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,...) Show SMILES Cc1nc(F)ccc1[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C27H28F3N9/c1-15-18(5-6-21(28)35-15)23(20-12-39(38-37-20)27(7-8-27)25(29)30)36-17-9-16(11-31)22-19(10-17)24(34-14-33-22)32-13-26(2,3)4/h5-6,9-10,12,14,23,25,36H,7-8,13H2,1-4H3,(H,32,33,34)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270594 ((S)-5-((1- (bicyclo[1.1.1]pentan- 1-yl)-1H-1,2,3- ...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C12CC(C1)C2 |r| Show InChI InChI=1S/C31H33ClN8O/c1-30(2,3)16-33-28-23-10-19(11-24(32)26(23)34-17-35-28)36-27(25-15-40(38-37-25)31-12-18(13-31)14-31)21-6-5-7-22-20(21)8-9-39(4)29(22)41/h5-11,15,17-18,27,36H,12-14,16H2,1-4H3,(H,33,34,35)/t18?,27-,31?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270590 ((S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,...) Show SMILES Cc1nc(F)ccc1[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C27H28F3N9/c1-15-18(5-6-21(28)35-15)23(20-12-39(38-37-20)27(7-8-27)25(29)30)36-17-9-16(11-31)22-19(10-17)24(34-14-33-22)32-13-26(2,3)4/h5-6,9-10,12,14,23,25,36H,7-8,13H2,1-4H3,(H,32,33,34)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270589 ((S)-8-chloro-N6-((1- (1- (difluoromethyl) cyclopro...) Show SMILES Cc1nc(F)ccc1[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C26H28ClF3N8/c1-14-16(5-6-20(28)34-14)22(19-11-38(37-36-19)26(7-8-26)24(29)30)35-15-9-17-21(18(27)10-15)32-13-33-23(17)31-12-25(2,3)4/h5-6,9-11,13,22,24,35H,7-8,12H2,1-4H3,(H,31,32,33)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270589 ((S)-8-chloro-N6-((1- (1- (difluoromethyl) cyclopro...) Show SMILES Cc1nc(F)ccc1[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C26H28ClF3N8/c1-14-16(5-6-20(28)34-14)22(19-11-38(37-36-19)26(7-8-26)24(29)30)35-15-9-17-21(18(27)10-15)32-13-33-23(17)31-12-25(2,3)4/h5-6,9-11,13,22,24,35H,7-8,12H2,1-4H3,(H,31,32,33)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270582 ((S)-6-(((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)C#N Show InChI InChI=1S/C26H27FN8/c1-26(2,3)14-29-25-21-11-19(10-17(12-28)23(21)30-15-31-25)32-24(16-4-6-18(27)7-5-16)22-13-35(34-33-22)20-8-9-20/h4-7,10-11,13,15,20,24,32H,8-9,14H2,1-3H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270582 ((S)-6-(((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12)C#N Show InChI InChI=1S/C26H27FN8/c1-26(2,3)14-29-25-21-11-19(10-17(12-28)23(21)30-15-31-25)32-24(16-4-6-18(27)7-5-16)22-13-35(34-33-22)20-8-9-20/h4-7,10-11,13,15,20,24,32H,8-9,14H2,1-3H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270593 ((S)-5-(((8-chloro-4- (neopentylamino) quinazolin-6...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C30H31ClF2N8O/c1-29(2,3)15-34-26-21-12-17(13-22(31)24(21)35-16-36-26)37-25(23-14-41(39-38-23)30(9-10-30)28(32)33)19-6-5-7-20-18(19)8-11-40(4)27(20)42/h5-8,11-14,16,25,28,37H,9-10,15H2,1-4H3,(H,34,35,36)/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270587 ((S)-6-(((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3...) Show SMILES CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3CC3)c3ccccc3Cl)cc12)C#N Show InChI InChI=1S/C26H27ClN8/c1-26(2,3)14-29-25-20-11-17(10-16(12-28)23(20)30-15-31-25)32-24(19-6-4-5-7-21(19)27)22-13-35(34-33-22)18-8-9-18/h4-7,10-11,13,15,18,24,32H,8-9,14H2,1-3H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270593 ((S)-5-(((8-chloro-4- (neopentylamino) quinazolin-6...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(Cl)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C30H31ClF2N8O/c1-29(2,3)15-34-26-21-12-17(13-22(31)24(21)35-16-36-26)37-25(23-14-41(39-38-23)30(9-10-30)28(32)33)19-6-5-7-20-18(19)8-11-40(4)27(20)42/h5-8,11-14,16,25,28,37H,9-10,15H2,1-4H3,(H,34,35,36)/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270587 ((S)-6-(((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3...) Show SMILES CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3CC3)c3ccccc3Cl)cc12)C#N Show InChI InChI=1S/C26H27ClN8/c1-26(2,3)14-29-25-20-11-17(10-16(12-28)23(20)30-15-31-25)32-24(19-6-4-5-7-21(19)27)22-13-35(34-33-22)18-8-9-18/h4-7,10-11,13,15,18,24,32H,8-9,14H2,1-3H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270575 ((S)-3-((1- cyclopropyl-1H- 1,2,3-triazol-4- yl)((4...) Show SMILES CC(C)(C)CNc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3cccc(c3)C#N)cc12 Show InChI InChI=1S/C26H28N8/c1-26(2,3)15-28-25-21-12-19(7-10-22(21)29-16-30-25)31-24(18-6-4-5-17(11-18)13-27)23-14-34(33-32-23)20-8-9-20/h4-7,10-12,14,16,20,24,31H,8-9,15H2,1-3H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270583 ((S)-8-bromo-N6-((1- cyclopropyl-1H- 1,2,3-triazol-...) Show SMILES CC(C)(C)CNc1ncnc2c(Br)cc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C25H27BrFN7/c1-25(2,3)13-28-24-19-10-17(11-20(26)23(19)29-14-30-24)31-22(15-4-6-16(27)7-5-15)21-12-34(33-32-21)18-8-9-18/h4-7,10-12,14,18,22,31H,8-9,13H2,1-3H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270575 ((S)-3-((1- cyclopropyl-1H- 1,2,3-triazol-4- yl)((4...) Show SMILES CC(C)(C)CNc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3cccc(c3)C#N)cc12 Show InChI InChI=1S/C26H28N8/c1-26(2,3)15-28-25-21-12-19(7-10-22(21)29-16-30-25)31-24(18-6-4-5-17(11-18)13-27)23-14-34(33-32-23)20-8-9-20/h4-7,10-12,14,16,20,24,31H,8-9,15H2,1-3H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270583 ((S)-8-bromo-N6-((1- cyclopropyl-1H- 1,2,3-triazol-...) Show SMILES CC(C)(C)CNc1ncnc2c(Br)cc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C25H27BrFN7/c1-25(2,3)13-28-24-19-10-17(11-20(26)23(19)29-14-30-24)31-22(15-4-6-16(27)7-5-15)21-12-34(33-32-21)18-8-9-18/h4-7,10-12,14,18,22,31H,8-9,13H2,1-3H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270584 ((S)-8-chloro-N6-((1- (1- (fluoromethyl) cyclopropy...) Show SMILES CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3(CF)CC3)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C26H28ClF2N7/c1-25(2,3)14-30-24-19-10-18(11-20(27)23(19)31-15-32-24)33-22(16-4-6-17(29)7-5-16)21-12-36(35-34-21)26(13-28)8-9-26/h4-7,10-12,15,22,33H,8-9,13-14H2,1-3H3,(H,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270584 ((S)-8-chloro-N6-((1- (1- (fluoromethyl) cyclopropy...) Show SMILES CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3(CF)CC3)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C26H28ClF2N7/c1-25(2,3)14-30-24-19-10-18(11-20(27)23(19)31-15-32-24)33-22(16-4-6-17(29)7-5-16)21-12-36(35-34-21)26(13-28)8-9-26/h4-7,10-12,15,22,33H,8-9,13-14H2,1-3H3,(H,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270585 ((S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromet...) Show SMILES CC(C)(C)CNc1ncnc2c(cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12)C#N |r| Show InChI InChI=1S/C28H26F3N9S/c1-26(2,3)13-33-25-19-10-17(9-16(11-32)22(19)34-14-35-25)37-23(18-5-4-6-20-24(18)41-15-36-20)21-12-40(39-38-21)27(7-8-27)28(29,30)31/h4-6,9-10,12,14-15,23,37H,7-8,13H2,1-3H3,(H,33,34,35)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270588 ((S)-6-(((2- chlorophenyl)(1-(1- cyanocyclopropyl)-...) Show SMILES CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3(CC3)C#N)c3ccccc3Cl)cc12)C#N Show InChI InChI=1S/C27H26ClN9/c1-26(2,3)15-31-25-20-11-18(10-17(12-29)23(20)32-16-33-25)34-24(19-6-4-5-7-21(19)28)22-13-37(36-35-22)27(14-30)8-9-27/h4-7,10-11,13,16,24,34H,8-9,15H2,1-3H3,(H,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270585 ((S)-6- ((benzo[d]thiazol-7- yl(1-(1- (trifluoromet...) Show SMILES CC(C)(C)CNc1ncnc2c(cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12)C#N |r| Show InChI InChI=1S/C28H26F3N9S/c1-26(2,3)13-33-25-19-10-17(9-16(11-32)22(19)34-14-35-25)37-23(18-5-4-6-20-24(18)41-15-36-20)21-12-40(39-38-21)27(7-8-27)28(29,30)31/h4-6,9-10,12,14-15,23,37H,7-8,13H2,1-3H3,(H,33,34,35)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270588 ((S)-6-(((2- chlorophenyl)(1-(1- cyanocyclopropyl)-...) Show SMILES CC(C)(C)CNc1ncnc2c(cc(NC(c3cn(nn3)C3(CC3)C#N)c3ccccc3Cl)cc12)C#N Show InChI InChI=1S/C27H26ClN9/c1-26(2,3)15-31-25-20-11-18(10-17(12-29)23(20)32-16-33-25)34-24(19-6-4-5-7-21(19)28)22-13-37(36-35-22)27(14-30)8-9-27/h4-7,10-11,13,16,24,34H,8-9,15H2,1-3H3,(H,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270577 ((S)-8-chloro-N6-((2- chlorophenyl)(1- cyclopropyl-...) Show SMILES CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3CC3)c3ccccc3Cl)cc12 Show InChI InChI=1S/C25H27Cl2N7/c1-25(2,3)13-28-24-18-10-15(11-20(27)22(18)29-14-30-24)31-23(17-6-4-5-7-19(17)26)21-12-34(33-32-21)16-8-9-16/h4-7,10-12,14,16,23,31H,8-9,13H2,1-3H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270577 ((S)-8-chloro-N6-((2- chlorophenyl)(1- cyclopropyl-...) Show SMILES CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3CC3)c3ccccc3Cl)cc12 Show InChI InChI=1S/C25H27Cl2N7/c1-25(2,3)13-28-24-18-10-15(11-20(27)22(18)29-14-30-24)31-23(17-6-4-5-7-19(17)26)21-12-34(33-32-21)16-8-9-16/h4-7,10-12,14,16,23,31H,8-9,13H2,1-3H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270569 ((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC(C)(C)CNc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C25H28FN7/c1-25(2,3)14-27-24-20-12-18(8-11-21(20)28-15-29-24)30-23(16-4-6-17(26)7-5-16)22-13-33(32-31-22)19-9-10-19/h4-8,11-13,15,19,23,30H,9-10,14H2,1-3H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270569 ((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC(C)(C)CNc1ncnc2ccc(NC(c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C25H28FN7/c1-25(2,3)14-27-24-20-12-18(8-11-21(20)28-15-29-24)30-23(16-4-6-17(26)7-5-16)22-13-33(32-31-22)19-9-10-19/h4-8,11-13,15,19,23,30H,9-10,14H2,1-3H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270598 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((...) Show SMILES CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccccc1 |r| Show InChI InChI=1S/C30H29Cl2FN8/c1-2-40-12-10-22(11-13-40)41-17-27(38-39-41)28(19-6-4-3-5-7-19)36-21-14-23-29(25(32)16-21)34-18-35-30(23)37-20-8-9-26(33)24(31)15-20/h3-9,14-18,22,28,36H,2,10-13H2,1H3,(H,34,35,37)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270598 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((...) Show SMILES CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccccc1 |r| Show InChI InChI=1S/C30H29Cl2FN8/c1-2-40-12-10-22(11-13-40)41-17-27(38-39-41)28(19-6-4-3-5-7-19)36-21-14-23-29(25(32)16-21)34-18-35-30(23)37-20-8-9-26(33)24(31)15-20/h3-9,14-18,22,28,36H,2,10-13H2,1H3,(H,34,35,37)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270570 ((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC(C)(C)CNc1ncnc2ccc(N[C@H](c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12 |r| Show InChI InChI=1S/C25H28FN7/c1-25(2,3)14-27-24-20-12-18(8-11-21(20)28-15-29-24)30-23(16-4-6-17(26)7-5-16)22-13-33(32-31-22)19-9-10-19/h4-8,11-13,15,19,23,30H,9-10,14H2,1-3H3,(H,27,28,29)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270570 ((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC(C)(C)CNc1ncnc2ccc(N[C@H](c3cn(nn3)C3CC3)c3ccc(F)cc3)cc12 |r| Show InChI InChI=1S/C25H28FN7/c1-25(2,3)14-27-24-20-12-18(8-11-21(20)28-15-29-24)30-23(16-4-6-17(26)7-5-16)22-13-33(32-31-22)19-9-10-19/h4-8,11-13,15,19,23,30H,9-10,14H2,1-3H3,(H,27,28,29)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270586 ((S)-N6- (benzo[d]thiazol-7- yl(1-(1- (trifluoromet...) Show SMILES CC(C)(C)CNc1ncnc2c(Br)cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12 |r| Show InChI InChI=1S/C27H26BrF3N8S/c1-25(2,3)12-32-24-17-9-15(10-18(28)21(17)33-13-34-24)36-22(16-5-4-6-19-23(16)40-14-35-19)20-11-39(38-37-20)26(7-8-26)27(29,30)31/h4-6,9-11,13-14,22,36H,7-8,12H2,1-3H3,(H,32,33,34)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270586 ((S)-N6- (benzo[d]thiazol-7- yl(1-(1- (trifluoromet...) Show SMILES CC(C)(C)CNc1ncnc2c(Br)cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12 |r| Show InChI InChI=1S/C27H26BrF3N8S/c1-25(2,3)12-32-24-17-9-15(10-18(28)21(17)33-13-34-24)36-22(16-5-4-6-19-23(16)40-14-35-19)20-11-39(38-37-20)26(7-8-26)27(29,30)31/h4-6,9-11,13-14,22,36H,7-8,12H2,1-3H3,(H,32,33,34)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270603 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- (p...) Show SMILES Fc1ccc(Nc2ncnc3c(Cl)cc(N[C@H](c4cn(nn4)C4CCNCC4)c4ccccc4)cc23)cc1Cl |r| Show InChI InChI=1S/C28H25Cl2FN8/c29-22-13-18(6-7-24(22)31)36-28-21-12-19(14-23(30)27(21)33-16-34-28)35-26(17-4-2-1-3-5-17)25-15-39(38-37-25)20-8-10-32-11-9-20/h1-7,12-16,20,26,32,35H,8-11H2,(H,33,34,36)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270603 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- (p...) Show SMILES Fc1ccc(Nc2ncnc3c(Cl)cc(N[C@H](c4cn(nn4)C4CCNCC4)c4ccccc4)cc23)cc1Cl |r| Show InChI InChI=1S/C28H25Cl2FN8/c29-22-13-18(6-7-24(22)31)36-28-21-12-19(14-23(30)27(21)33-16-34-28)35-26(17-4-2-1-3-5-17)25-15-39(38-37-25)20-8-10-32-11-9-20/h1-7,12-16,20,26,32,35H,8-11H2,(H,33,34,36)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270581 ((S)-8-chloro-N6-((4- fluorophenyl)(1-(1- (trifluor...) Show SMILES CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3(CC3)C(F)(F)F)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C26H26ClF4N7/c1-24(2,3)13-32-23-18-10-17(11-19(27)22(18)33-14-34-23)35-21(15-4-6-16(28)7-5-15)20-12-38(37-36-20)25(8-9-25)26(29,30)31/h4-7,10-12,14,21,35H,8-9,13H2,1-3H3,(H,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270581 ((S)-8-chloro-N6-((4- fluorophenyl)(1-(1- (trifluor...) Show SMILES CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(nn3)C3(CC3)C(F)(F)F)c3ccc(F)cc3)cc12 Show InChI InChI=1S/C26H26ClF4N7/c1-24(2,3)13-32-23-18-10-17(11-19(27)22(18)33-14-34-23)35-21(15-4-6-16(28)7-5-15)20-12-38(37-36-20)25(8-9-25)26(29,30)31/h4-7,10-12,14,21,35H,8-9,13H2,1-3H3,(H,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270571 ((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC1(CNc2ncnc3ccc(NC(c4cn(nn4)C4CC4)c4ccc(F)cc4)cc23)CCOCC1 Show InChI InChI=1S/C27H30FN7O/c1-27(10-12-36-13-11-27)16-29-26-22-14-20(6-9-23(22)30-17-31-26)32-25(18-2-4-19(28)5-3-18)24-15-35(34-33-24)21-7-8-21/h2-6,9,14-15,17,21,25,32H,7-8,10-13,16H2,1H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270571 ((S)-N6-((1- cyclopropyl-1H- 1,2,3-triazol-4-yl)(4-...) Show SMILES CC1(CNc2ncnc3ccc(NC(c4cn(nn4)C4CC4)c4ccc(F)cc4)cc23)CCOCC1 Show InChI InChI=1S/C27H30FN7O/c1-27(10-12-36-13-11-27)16-29-26-22-14-20(6-9-23(22)30-17-31-26)32-25(18-2-4-19(28)5-3-18)24-15-35(34-33-24)21-7-8-21/h2-6,9,14-15,17,21,25,32H,7-8,10-13,16H2,1H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Protein-arginine deiminase type-4 (Homo sapiens (Human))	BDBM646150 (N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2...) Show SMILES COc1cc(cc2nc(-c3cc4ccc(nc4n3CC3CC3)[C@@H](C)NC(=O)c3cnn(C)c3)n(C)c12)C(=O)N1[C@H]2CC[C@@H]1[C@H](N)C2 |r,THB:36:38:43.45:41.40| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270578 ((S)-2-(4-(((8-chloro- 4- (neopentylamino) quinazol...) Show SMILES CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(CC(O)=O)nn3)c3ccccc3Cl)cc12 Show InChI InChI=1S/C24H25Cl2N7O2/c1-24(2,3)12-27-23-16-8-14(9-18(26)21(16)28-13-29-23)30-22(15-6-4-5-7-17(15)25)19-10-33(32-31-19)11-20(34)35/h4-10,13,22,30H,11-12H2,1-3H3,(H,34,35)(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270576 ((S)-N6-((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3...) Show SMILES CC(C)(C)CNc1ncnc2ccc(N[C@H](c3cn(nn3)C3CC3)c3ccccc3Cl)cc12 |r| Show InChI InChI=1S/C25H28ClN7/c1-25(2,3)14-27-24-19-12-16(8-11-21(19)28-15-29-24)30-23(18-6-4-5-7-20(18)26)22-13-33(32-31-22)17-9-10-17/h4-8,11-13,15,17,23,30H,9-10,14H2,1-3H3,(H,27,28,29)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270578 ((S)-2-(4-(((8-chloro- 4- (neopentylamino) quinazol...) Show SMILES CC(C)(C)CNc1ncnc2c(Cl)cc(NC(c3cn(CC(O)=O)nn3)c3ccccc3Cl)cc12 Show InChI InChI=1S/C24H25Cl2N7O2/c1-24(2,3)12-27-23-16-8-14(9-18(26)21(16)28-13-29-23)30-22(15-6-4-5-7-17(15)25)19-10-33(32-31-19)11-20(34)35/h4-10,13,22,30H,11-12H2,1-3H3,(H,34,35)(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270576 ((S)-N6-((2- chlorophenyl)(1- cyclopropyl-1H- 1,2,3...) Show SMILES CC(C)(C)CNc1ncnc2ccc(N[C@H](c3cn(nn3)C3CC3)c3ccccc3Cl)cc12 |r| Show InChI InChI=1S/C25H28ClN7/c1-25(2,3)14-27-24-19-12-16(8-11-21(19)28-15-29-24)30-23(18-6-4-5-7-20(18)26)22-13-33(32-31-22)17-9-10-17/h4-8,11-13,15,17,23,30H,9-10,14H2,1-3H3,(H,27,28,29)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270604 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((...) Show SMILES CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C30H28Cl3FN8/c1-2-41-11-9-22(10-12-41)42-16-27(39-40-42)28(18-3-5-19(31)6-4-18)37-21-13-23-29(25(33)15-21)35-17-36-30(23)38-20-7-8-26(34)24(32)14-20/h3-8,13-17,22,28,37H,2,9-12H2,1H3,(H,35,36,38)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270604 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((...) Show SMILES CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C30H28Cl3FN8/c1-2-41-11-9-22(10-12-41)42-16-27(39-40-42)28(18-3-5-19(31)6-4-18)37-21-13-23-29(25(33)15-21)35-17-36-30(23)38-20-7-8-26(34)24(32)14-20/h3-8,13-17,22,28,37H,2,9-12H2,1H3,(H,35,36,38)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Protein-arginine deiminase type-4 (Homo sapiens (Human))	BDBM646149 (N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2...) Show SMILES COc1cc(cc2nc(-c3cc4ccc(nc4n3CC3CC3)[C@@H](C)NC(=O)C34CC(C3)(C4)C#N)n(C)c12)C(=O)N1[C@H]2CC[C@@H]1[C@H](N)C2 |r,THB:37:39:44.46:42.41| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	18.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

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