Compile Data Set for Download or QSAR

Found 153 hits with Last Name = 'yoneda' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179992 (US9676720, Example 2) Show SMILES C\C=C\c1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C29H28N4O4S/c1-2-7-22-8-5-9-25(18-22)24-15-13-23(14-16-24)20-33(38(36,37)28-12-3-4-17-30-28)21-26-10-6-11-27(32-26)31-19-29(34)35/h2-18H,19-21H2,1H3,(H,31,32)(H,34,35)/b7-2+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.530	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179995 (US9676720, Example 7) Show SMILES CCOc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C28H28N4O5S/c1-2-37-25-9-5-7-23(17-25)22-14-12-21(13-15-22)19-32(38(35,36)27-11-3-4-16-29-27)20-24-8-6-10-26(31-24)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.610	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180045 (US9676720, Comparative example 16) Show SMILES CC#Cc1ccccc1-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C29H26N4O4S/c1-2-8-23-9-3-4-11-26(23)24-16-14-22(15-17-24)20-33(38(36,37)28-13-5-6-18-30-28)21-25-10-7-12-27(32-25)31-19-29(34)35/h3-7,9-18H,19-21H2,1H3,(H,31,32)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.75	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179994 (US9676720, Example 6) Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccnc2)cc1 Show InChI InChI=1S/C29H26N4O4S/c1-2-6-22-7-3-8-25(17-22)24-14-12-23(13-15-24)20-33(38(36,37)27-10-5-16-30-18-27)21-26-9-4-11-28(32-26)31-19-29(34)35/h3-5,7-18H,19-21H2,1H3,(H,31,32)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.75	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179998 (US9676720, Example 11) Show SMILES CCOc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccs2)cc1 Show InChI InChI=1S/C27H27N3O5S2/c1-2-35-24-8-3-6-22(16-24)21-13-11-20(12-14-21)18-30(37(33,34)27-10-5-15-36-27)19-23-7-4-9-25(29-23)28-17-26(31)32/h3-16H,2,17-19H2,1H3,(H,28,29)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.790	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179996 (US9676720, Example 9) Show SMILES CCOc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccnc2)cc1 Show InChI InChI=1S/C28H28N4O5S/c1-2-37-25-8-3-6-23(16-25)22-13-11-21(12-14-22)19-32(38(35,36)26-9-5-15-29-17-26)20-24-7-4-10-27(31-24)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179993 (US9676720, Example 4) Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C29H26N4O4S/c1-2-7-22-8-5-9-25(18-22)24-15-13-23(14-16-24)20-33(38(36,37)28-12-3-4-17-30-28)21-26-10-6-11-27(32-26)31-19-29(34)35/h3-6,8-18H,19-21H2,1H3,(H,31,32)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180000 (US9676720, Example 14) Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccs2)cc1 Show InChI InChI=1S/C28H25N3O4S2/c1-2-6-21-7-3-8-24(17-21)23-14-12-22(13-15-23)19-31(37(34,35)28-11-5-16-36-28)20-25-9-4-10-26(30-25)29-18-27(32)33/h3-5,7-17H,18-20H2,1H3,(H,29,30)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179999 (US9676720, Example 12) Show SMILES CCOc1cccc(n1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C27H27N5O5S/c1-2-37-25-10-6-8-23(31-25)21-14-12-20(13-15-21)18-32(38(35,36)26-11-3-4-16-28-26)19-22-7-5-9-24(30-22)29-17-27(33)34/h3-16H,2,17-19H2,1H3,(H,29,30)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.940	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180002 (US9676720, Example 16) Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C30H27N3O4S/c1-2-8-23-9-6-10-26(19-23)25-17-15-24(16-18-25)21-33(38(36,37)28-12-4-3-5-13-28)22-27-11-7-14-29(32-27)31-20-30(34)35/h3-7,9-19H,20-22H2,1H3,(H,31,32)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.950	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179997 (US9676720, Example 10) Show SMILES CCOc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C29H29N3O5S/c1-2-37-26-10-6-8-24(18-26)23-16-14-22(15-17-23)20-32(38(35,36)27-11-4-3-5-12-27)21-25-9-7-13-28(31-25)30-19-29(33)34/h3-18H,2,19-21H2,1H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.970	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180003 (US9676720, Example 18) Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccsc2)cc1 Show InChI InChI=1S/C28H25N3O4S2/c1-2-5-21-6-3-7-24(16-21)23-12-10-22(11-13-23)18-31(37(34,35)26-14-15-36-20-26)19-25-8-4-9-27(30-25)29-17-28(32)33/h3-4,6-16,20H,17-19H2,1H3,(H,29,30)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.990	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119438 (BDBM119693 | US8685986, 12) Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2ccoc2)cc1 Show InChI InChI=1S/C23H18FN3O4/c24-18-7-5-15(6-8-18)19-11-20(17-9-10-31-13-17)26-21(19)23(29)25-12-14-1-3-16(4-2-14)22(28)27-30/h1-11,13,26,30H,12H2,(H,25,29)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	-52.0	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180020 (US9676720, Comparative example 8) Show SMILES CCCc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C29H30N4O4S/c1-2-7-22-8-5-9-25(18-22)24-15-13-23(14-16-24)20-33(38(36,37)28-12-3-4-17-30-28)21-26-10-6-11-27(32-26)31-19-29(34)35/h3-6,8-18H,2,7,19-21H2,1H3,(H,31,32)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180024 (US9676720, Comparative example 11) Show SMILES COc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C27H26N4O5S/c1-36-24-8-4-6-22(16-24)21-13-11-20(12-14-21)18-31(37(34,35)26-10-2-3-15-28-26)19-23-7-5-9-25(30-23)29-17-27(32)33/h2-16H,17-19H2,1H3,(H,29,30)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.20	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180019 (US9676720, Comparative example 7) Show SMILES CCc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C28H28N4O4S/c1-2-21-7-5-8-24(17-21)23-14-12-22(13-15-23)19-32(37(35,36)27-11-3-4-16-29-27)20-25-9-6-10-26(31-25)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180004 (US9676720, Example 19) Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccc(F)c2)cc1 Show InChI InChI=1S/C30H26FN3O4S/c1-2-6-22-7-3-8-25(17-22)24-15-13-23(14-16-24)20-34(39(37,38)28-11-4-9-26(31)18-28)21-27-10-5-12-29(33-27)32-19-30(35)36/h3-5,7-18H,19-21H2,1H3,(H,32,33)(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180005 (US9676720, Comparative example 1) Show SMILES OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-c2ccccc2)S(=O)(=O)c2ccccn2)n1 Show InChI InChI=1S/C26H24N4O4S/c31-26(32)17-28-24-10-6-9-23(29-24)19-30(35(33,34)25-11-4-5-16-27-25)18-20-12-14-22(15-13-20)21-7-2-1-3-8-21/h1-16H,17-19H2,(H,28,29)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119442 (US8685986, 17) Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2ccccc2)o1 Show InChI InChI=1S/C23H18FN3O4/c24-16-8-6-14(7-9-16)18-12-19(15-4-2-1-3-5-15)26-21(18)23(29)25-13-17-10-11-20(31-17)22(28)27-30/h1-12,26,30H,13H2,(H,25,29)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	-51.2	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180021 (US9676720, Comparative example 9) Show SMILES CC\C=C\c1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C30H30N4O4S/c1-2-3-8-23-9-6-10-26(19-23)25-16-14-24(15-17-25)21-34(39(37,38)29-13-4-5-18-31-29)22-27-11-7-12-28(33-27)32-20-30(35)36/h3-19H,2,20-22H2,1H3,(H,32,33)(H,35,36)/b8-3+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180022 (US9676720, Comparative example 10) Show SMILES OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-c2cccc(CC=C)c2)S(=O)(=O)c2ccccn2)n1 Show InChI InChI=1S/C29H28N4O4S/c1-2-7-22-8-5-9-25(18-22)24-15-13-23(14-16-24)20-33(38(36,37)28-12-3-4-17-30-28)21-26-10-6-11-27(32-26)31-19-29(34)35/h2-6,8-18H,1,7,19-21H2,(H,31,32)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.70	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119432 (US8685986, 3) Show SMILES OC(=O)c1[nH]c(cc1-c1ccc(F)cc1)-c1cccs1 Show InChI InChI=1S/C15H10FNO2S/c16-10-5-3-9(4-6-10)11-8-12(13-2-1-7-20-13)17-14(11)15(18)19/h1-8,17H,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.90	-50.6	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180025 (US9676720, Comparative example 12) Show SMILES CCCOc1cccc(n1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C28H29N5O5S/c1-2-17-38-26-10-6-8-24(32-26)22-14-12-21(13-15-22)19-33(39(36,37)27-11-3-4-16-29-27)20-23-7-5-9-25(31-23)30-18-28(34)35/h3-16H,2,17-20H2,1H3,(H,30,31)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180018 (US9676720, Comparative example 6) Show SMILES Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C27H26N4O4S/c1-20-6-4-7-23(16-20)22-13-11-21(12-14-22)18-31(36(34,35)26-10-2-3-15-28-26)19-24-8-5-9-25(30-24)29-17-27(32)33/h2-16H,17-19H2,1H3,(H,29,30)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.20	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180026 (US9676720, Comparative example 13) Show SMILES CCOc1ccccc1-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C28H28N4O5S/c1-2-37-25-10-4-3-9-24(25)22-15-13-21(14-16-22)19-32(38(35,36)27-12-5-6-17-29-27)20-23-8-7-11-26(31-23)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.60	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119433 (US8685986, 4) Show SMILES OC(=O)c1[nH]c(cc1-c1ccc(O)cc1)-c1ccoc1 Show InChI InChI=1S/C15H11NO4/c17-11-3-1-9(2-4-11)12-7-13(10-5-6-20-8-10)16-14(12)15(18)19/h1-8,16-17H,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.80	-49.6	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119441 (US8685986, 16) Show SMILES COc1ccc(cc1)-c1cc([nH]c1C(=O)Nc1ccc(o1)C(=O)NO)-c1ccccc1 Show InChI InChI=1S/C23H19N3O5/c1-30-16-9-7-14(8-10-16)17-13-18(15-5-3-2-4-6-15)24-21(17)23(28)25-20-12-11-19(31-20)22(27)26-29/h2-13,24,29H,1H3,(H,25,28)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.10	-49.4	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180038 (US9676720, Comparative example 15) Show SMILES CCOc1cc(ccn1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C28H28N4O5S/c1-2-37-27-17-23(15-16-29-27)22-13-11-21(12-14-22)19-32(38(35,36)25-8-4-3-5-9-25)20-24-7-6-10-26(31-24)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180006 (US9676720, Comparative example 2) Show SMILES OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-c2ccccc2)S(=O)(=O)c2cccnc2)n1 Show InChI InChI=1S/C26H24N4O4S/c31-26(32)17-28-25-10-4-8-23(29-25)19-30(35(33,34)24-9-5-15-27-16-24)18-20-11-13-22(14-12-20)21-6-2-1-3-7-21/h1-16H,17-19H2,(H,28,29)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.80	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119435 (US8685986, 6) Show SMILES COC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2cccs2)nc1 Show InChI InChI=1S/C23H18FN3O3S/c1-30-23(29)15-6-9-17(25-12-15)13-26-22(28)21-18(14-4-7-16(24)8-5-14)11-19(27-21)20-3-2-10-31-20/h2-12,27H,13H2,1H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.80	-48.9	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119437 (US8685986, 11) Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2cccs2)nc1 Show InChI InChI=1S/C22H17FN4O3S/c23-15-6-3-13(4-7-15)17-10-18(19-2-1-9-31-19)26-20(17)22(29)25-12-16-8-5-14(11-24-16)21(28)27-30/h1-11,26,30H,12H2,(H,25,29)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.80	-48.9	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180007 (US9676720, Comparative example 3) Show SMILES OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-c2ccc(F)cc2)S(=O)(=O)c2cccnc2)n1 Show InChI InChI=1S/C26H23FN4O4S/c27-22-12-10-21(11-13-22)20-8-6-19(7-9-20)17-31(36(34,35)24-4-2-14-28-15-24)18-23-3-1-5-25(30-23)29-16-26(32)33/h1-15H,16-18H2,(H,29,30)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.40	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119436 (US8685986, 9) Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(O)cc2)-c2ccoc2)cc1 Show InChI InChI=1S/C23H19N3O5/c27-18-7-5-15(6-8-18)19-11-20(17-9-10-31-13-17)25-21(19)23(29)24-12-14-1-3-16(4-2-14)22(28)26-30/h1-11,13,25,27,30H,12H2,(H,24,29)(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.40	-48.5	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180046 (US9676720, Comparative example 17) Show SMILES CC#Cc1ccc(cc1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C29H26N4O4S/c1-2-6-22-10-14-24(15-11-22)25-16-12-23(13-17-25)20-33(38(36,37)28-9-3-4-18-30-28)21-26-7-5-8-27(32-26)31-19-29(34)35/h3-5,7-18H,19-21H2,1H3,(H,31,32)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.80	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119434 (US8685986, 5) Show SMILES COC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(O)cc2)-c2ccoc2)cc1 Show InChI InChI=1S/C24H20N2O5/c1-30-24(29)17-4-2-15(3-5-17)13-25-23(28)22-20(16-6-8-19(27)9-7-16)12-21(26-22)18-10-11-31-14-18/h2-12,14,26-27H,13H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	-47.3	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119443 (US8685986, 18) Show SMILES COc1ccc(cc1)-c1cc([nH]c1C(=O)Nc1cccc(CC(=O)NO)c1)-c1ccccc1 Show InChI InChI=1S/C26H23N3O4/c1-33-21-12-10-18(11-13-21)22-16-23(19-7-3-2-4-8-19)28-25(22)26(31)27-20-9-5-6-17(14-20)15-24(30)29-32/h2-14,16,28,32H,15H2,1H3,(H,27,31)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.20	-46.6	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119440 (BDBM119696 | US8685986, 15) Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccoc2)-c2ccc(O)cc2)cc1 Show InChI InChI=1S/C23H19N3O5/c27-18-7-5-15(6-8-18)20-11-19(17-9-10-31-13-17)21(25-20)23(29)24-12-14-1-3-16(4-2-14)22(28)26-30/h1-11,13,25,27,30H,12H2,(H,24,29)(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	9.40	-46.6	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180027 (US9676720, Comparative example 14) Show SMILES CCOc1ccc(cc1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C28H28N4O5S/c1-2-37-25-15-13-23(14-16-25)22-11-9-21(10-12-22)19-32(38(35,36)27-8-3-4-17-29-27)20-24-6-5-7-26(31-24)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>10	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180009 (US9676720, Comparative example 5) Show SMILES Cc1cnc(s1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C24H23N5O4S2/c1-17-13-27-24(34-17)19-10-8-18(9-11-19)15-29(35(32,33)22-7-2-3-12-25-22)16-20-5-4-6-21(28-20)26-14-23(30)31/h2-13H,14-16H2,1H3,(H,26,28)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>10	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM180008 (US9676720, Comparative example 4) Show SMILES OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-c2ccc(Cl)cc2)S(=O)(=O)c2cccnc2)n1 Show InChI InChI=1S/C26H23ClN4O4S/c27-22-12-10-21(11-13-22)20-8-6-19(7-9-20)17-31(36(34,35)24-4-2-14-28-15-24)18-23-3-1-5-25(30-23)29-16-26(32)33/h1-15H,16-18H2,(H,29,30)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>10	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
UBE INDUSTRIES, LTD. US Patent					Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...				US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119439 (BDBM119694 | US8685986, 13) Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(O)cc2)-c2cccs2)cc1 Show InChI InChI=1S/C23H19N3O4S/c27-17-9-7-15(8-10-17)18-12-19(20-2-1-11-31-20)25-21(18)23(29)24-13-14-3-5-16(6-4-14)22(28)26-30/h1-12,25,27,30H,13H2,(H,24,29)(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13	-45.8	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50506542 (CHEMBL4443289) Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc3oc(cc23)C(O)=O)S(=O)(=O)c2cccnc2)cc1 Show InChI InChI=1S/C26H26N2O5S/c1-26(2,3)20-11-9-18(10-12-20)16-28(34(31,32)21-7-5-13-27-15-21)17-19-6-4-8-23-22(19)14-24(33-23)25(29)30/h4-15H,16-17H2,1-3H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UBE Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting				J Med Chem 61: 6869-6891 (2018) Article DOI: 10.1021/acs.jmedchem.8b00808 BindingDB Entry DOI: 10.7270/Q2125WXC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50506547 (C-533,536-02 | CP-533536-02 | Evatanepag sodium) Show SMILES [Na;v0+].[#6]C([#6])([#6])c1ccc(-[#6]-[#7](-[#6]-c2cccc(-[#8]-[#6]-[#6](-[#8-])=O)c2)S(=O)(=O)c2cccnc2)cc1 Show InChI InChI=1S/C25H28N2O5S/c1-25(2,3)21-11-9-19(10-12-21)16-27(33(30,31)23-8-5-13-26-15-23)17-20-6-4-7-22(14-20)32-18-24(28)29/h4-15H,16-18H2,1-3H3,(H,28,29)/p-1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UBE Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting				J Med Chem 61: 6869-6891 (2018) Article DOI: 10.1021/acs.jmedchem.8b00808 BindingDB Entry DOI: 10.7270/Q2125WXC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50506548 (CHEMBL4448995) Show SMILES CC(C)(C)c1ccc(CN(Cc2ccc3cc(oc3c2)C(O)=O)S(=O)(=O)c2cccnc2)cc1 Show InChI InChI=1S/C26H26N2O5S/c1-26(2,3)21-10-7-18(8-11-21)16-28(34(31,32)22-5-4-12-27-15-22)17-19-6-9-20-14-24(25(29)30)33-23(20)13-19/h4-15H,16-17H2,1-3H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UBE Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting				J Med Chem 61: 6869-6891 (2018) Article DOI: 10.1021/acs.jmedchem.8b00808 BindingDB Entry DOI: 10.7270/Q2125WXC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
UBE Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prostaglandin E2 from recombinant human full length EP3 receptor expressed in Chem-1 cell membranes after 60 mins by liquid scint...				J Med Chem 61: 6869-6891 (2018) Article DOI: 10.1021/acs.jmedchem.8b00808 BindingDB Entry DOI: 10.7270/Q2125WXC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
UBE Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting				J Med Chem 61: 6869-6891 (2018) Article DOI: 10.1021/acs.jmedchem.8b00808 BindingDB Entry DOI: 10.7270/Q2125WXC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
UBE Industries, Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prostaglandin E2 from recombinant human full length EP4 receptor expressed in Chem-1 cell membranes after 60 mins by liquid scint...				J Med Chem 61: 6869-6891 (2018) Article DOI: 10.1021/acs.jmedchem.8b00808 BindingDB Entry DOI: 10.7270/Q2125WXC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM192306 (US9187450, 52) Show SMILES CC(C)S(=O)(=O)N(C)Cc1cnc(nc1)N1CCC(CC1)c1nc2CC(C)(C)C[C@H](O)c2c(C2CCC(F)(F)CC2)c1[C@@H](F)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C39H49F6N5O3S/c1-23(2)54(52,53)49(5)22-24-20-46-36(47-21-24)50-16-12-27(13-17-50)35-33(34(40)26-6-8-28(9-7-26)39(43,44)45)31(25-10-14-38(41,42)15-11-25)32-29(48-35)18-37(3,4)19-30(32)51/h6-9,20-21,23,25,27,30,34,51H,10-19,22H2,1-5H3/t30-,34-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	37
Daiichi Sankyo Company, Limited US Patent					Assay Description A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and 5,5'...				US Patent US9187450 (2015) BindingDB Entry DOI: 10.7270/Q29022KM
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM192305 (US9187450, 51) Show SMILES CN(Cc1cnc(nc1)N1CCC(CC1)c1nc2CC(C)(C)C[C@H](O)c2c(C2CCC(F)(F)CC2)c1[C@@H](F)c1ccc(cc1)C(F)(F)F)S(C)(=O)=O |r| Show InChI InChI=1S/C37H45F6N5O3S/c1-35(2)17-27-30(28(49)18-35)29(23-9-13-36(39,40)14-10-23)31(32(38)24-5-7-26(8-6-24)37(41,42)43)33(46-27)25-11-15-48(16-12-25)34-44-19-22(20-45-34)21-47(3)52(4,50)51/h5-8,19-20,23,25,28,32,49H,9-18,21H2,1-4H3/t28-,32-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	37
Daiichi Sankyo Company, Limited US Patent					Assay Description A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and 5,5'...				US Patent US9187450 (2015) BindingDB Entry DOI: 10.7270/Q29022KM
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM192303 (US9187450, 49 | US9321747, 2) Show SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCN(CC1)c1ncc(OCC(CO)CO)cn1)c([C@@H](F)c1ccc(cc1)C(F)(F)F)c2C1CCC(F)(F)CC1 |r| Show InChI InChI=1S/C38H46F6N4O4/c1-36(2)15-28-31(29(51)16-36)30(23-7-11-37(40,41)12-8-23)32(33(39)24-3-5-26(6-4-24)38(42,43)44)34(47-28)25-9-13-48(14-10-25)35-45-17-27(18-46-35)52-21-22(19-49)20-50/h3-6,17-18,22-23,25,29,33,49-51H,7-16,19-21H2,1-2H3/t29-,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	37
Daiichi Sankyo Company, Limited US Patent					Assay Description A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and 5,5'...				US Patent US9187450 (2015) BindingDB Entry DOI: 10.7270/Q29022KM
					More data for this Ligand-Target Pair

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