Compile Data Set for Download or QSAR

Found 175 hits Enz. Inhib. hit(s) with all data for entry = 50044593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021624 (CHEMBL3297766 | US9145418, 23) Show SMILES CN(C)C1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C30H42ClN5O2/c1-34(2)25-11-13-35(14-12-25)20-27(21-7-4-3-5-8-21)33-29(37)17-26-18-32-30(38)28-16-23(19-36(26)28)22-9-6-10-24(31)15-22/h6,9-10,15-16,19,21,25-27H,3-5,7-8,11-14,17-18,20H2,1-2H3,(H,32,38)(H,33,37)/t26-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021620 (CHEMBL3297764 | US9145418, 26) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cc(Cl)ccc2F)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H37ClFN5O2/c1-33-9-11-34(12-10-33)18-25(19-5-3-2-4-6-19)32-27(36)15-22-16-31-28(37)26-13-20(17-35(22)26)23-14-21(29)7-8-24(23)30/h7-8,13-14,17,19,22,25H,2-6,9-12,15-16,18H2,1H3,(H,31,37)(H,32,36)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021622 (CHEMBL3297767) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C(C)(C)C)CC1 |r| Show InChI InChI=1S/C26H36ClN5O2/c1-26(2,3)23(17-31-10-8-30(4)9-11-31)29-24(33)14-21-15-28-25(34)22-13-19(16-32(21)22)18-6-5-7-20(27)12-18/h5-7,12-13,16,21,23H,8-11,14-15,17H2,1-4H3,(H,28,34)(H,29,33)/t21-,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021617 (CHEMBL3297761) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(F)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H38FN5O2/c1-32-10-12-33(13-11-32)19-25(20-6-3-2-4-7-20)31-27(35)16-24-17-30-28(36)26-15-22(18-34(24)26)21-8-5-9-23(29)14-21/h5,8-9,14-15,18,20,24-25H,2-4,6-7,10-13,16-17,19H2,1H3,(H,30,36)(H,31,35)/t24-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021649 (CHEMBL3298891) Show SMILES NC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C23H23FN4O2/c24-18-8-4-7-16(9-18)17-10-21-23(30)26-13-19(28(21)14-17)11-22(29)27-20(12-25)15-5-2-1-3-6-15/h1-10,14,19-20H,11-13,25H2,(H,26,30)(H,27,29)/t19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50021618 (CHEMBL3297762 | US9145418, 2) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H38ClN5O2/c1-32-10-12-33(13-11-32)19-25(20-6-3-2-4-7-20)31-27(35)16-24-17-30-28(36)26-15-22(18-34(24)26)21-8-5-9-23(29)14-21/h5,8-9,14-15,18,20,24-25H,2-4,6-7,10-13,16-17,19H2,1H3,(H,30,36)(H,31,35)/t24-,25+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM3 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021653 (CHEMBL3297759) Show SMILES NC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1)C1CCCCC1 |r| Show InChI InChI=1S/C23H29FN4O2/c24-18-8-4-7-16(9-18)17-10-21-23(30)26-13-19(28(21)14-17)11-22(29)27-20(12-25)15-5-2-1-3-6-15/h4,7-10,14-15,19-20H,1-3,5-6,11-13,25H2,(H,26,30)(H,27,29)/t19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021647 (CHEMBL3298889) Show SMILES NC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1ccnc(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C22H22FN5O2/c23-20-9-15(6-7-25-20)16-8-19-22(30)26-12-17(28(19)13-16)10-21(29)27-18(11-24)14-4-2-1-3-5-14/h1-9,13,17-18H,10-12,24H2,(H,26,30)(H,27,29)/t17-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021621 (CHEMBL3297765) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2ccnc(F)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C27H37FN6O2/c1-32-9-11-33(12-10-32)18-23(19-5-3-2-4-6-19)31-26(35)15-22-16-30-27(36)24-13-21(17-34(22)24)20-7-8-29-25(28)14-20/h7-8,13-14,17,19,22-23H,2-6,9-12,15-16,18H2,1H3,(H,30,36)(H,31,35)/t22-,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021650 (CHEMBL3298892) Show SMILES OC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1)C1CCCCC1 |r| Show InChI InChI=1S/C23H28FN3O3/c24-18-8-4-7-16(9-18)17-10-21-23(30)25-12-19(27(21)13-17)11-22(29)26-20(14-28)15-5-2-1-3-6-15/h4,7-10,13,15,19-20,28H,1-3,5-6,11-12,14H2,(H,25,30)(H,26,29)/t19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021619 (CHEMBL3297763) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2ccc(F)c(F)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H37F2N5O2/c1-33-9-11-34(12-10-33)18-25(19-5-3-2-4-6-19)32-27(36)15-22-16-31-28(37)26-14-21(17-35(22)26)20-7-8-23(29)24(30)13-20/h7-8,13-14,17,19,22,25H,2-6,9-12,15-16,18H2,1H3,(H,31,37)(H,32,36)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021618 (CHEMBL3297762 | US9145418, 2) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H38ClN5O2/c1-32-10-12-33(13-11-32)19-25(20-6-3-2-4-7-20)31-27(35)16-24-17-30-28(36)26-15-22(18-34(24)26)21-8-5-9-23(29)14-21/h5,8-9,14-15,18,20,24-25H,2-4,6-7,10-13,16-17,19H2,1H3,(H,30,36)(H,31,35)/t24-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021641 (CHEMBL3298822) Show SMILES Clc1nccc(n1)-c1cc2C(=O)NCC(CC(=O)NCC3CCCCC3)n2c1 Show InChI InChI=1S/C20H24ClN5O2/c21-20-22-7-6-16(25-20)14-8-17-19(28)24-11-15(26(17)12-14)9-18(27)23-10-13-4-2-1-3-5-13/h6-8,12-13,15H,1-5,9-11H2,(H,23,27)(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021624 (CHEMBL3297766 | US9145418, 23) Show SMILES CN(C)C1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C30H42ClN5O2/c1-34(2)25-11-13-35(14-12-25)20-27(21-7-4-3-5-8-21)33-29(37)17-26-18-32-30(38)28-16-23(19-36(26)28)22-9-6-10-24(31)15-22/h6,9-10,15-16,19,21,25-27H,3-5,7-8,11-14,17-18,20H2,1-2H3,(H,32,38)(H,33,37)/t26-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021643 (CHEMBL3298886) Show SMILES Clc1cccc(c1)-c1cc2C(=O)NCC(CC(=O)NCc3ccco3)n2c1 Show InChI InChI=1S/C20H18ClN3O3/c21-15-4-1-3-13(7-15)14-8-18-20(26)23-10-16(24(18)12-14)9-19(25)22-11-17-5-2-6-27-17/h1-8,12,16H,9-11H2,(H,22,25)(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50021625 (CHEMBL3298823) Show SMILES Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cn[nH]c2)c1 Show InChI InChI=1S/C19H18FN5O2/c20-15-3-1-2-12(4-15)7-21-18(26)6-16-10-22-19(27)17-5-13(11-25(16)17)14-8-23-24-9-14/h1-5,8-9,11,16H,6-7,10H2,(H,21,26)(H,22,27)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of CDK2 (unknown origin)				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021639 (CHEMBL3298820) Show SMILES Fc1cccc(c1)-c1cc2C(=O)NCC(CC(=O)NCC3CCCCC3)n2c1 Show InChI InChI=1S/C22H26FN3O2/c23-18-8-4-7-16(9-18)17-10-20-22(28)25-13-19(26(20)14-17)11-21(27)24-12-15-5-2-1-3-6-15/h4,7-10,14-15,19H,1-3,5-6,11-13H2,(H,24,27)(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021618 (CHEMBL3297762 | US9145418, 2) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H38ClN5O2/c1-32-10-12-33(13-11-32)19-25(20-6-3-2-4-7-20)31-27(35)16-24-17-30-28(36)26-15-22(18-34(24)26)21-8-5-9-23(29)14-21/h5,8-9,14-15,18,20,24-25H,2-4,6-7,10-13,16-17,19H2,1H3,(H,30,36)(H,31,35)/t24-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021651 (CHEMBL3298893) Show SMILES OC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C23H22FN3O3/c24-18-8-4-7-16(9-18)17-10-21-23(30)25-12-19(27(21)13-17)11-22(29)26-20(14-28)15-5-2-1-3-6-15/h1-10,13,19-20,28H,11-12,14H2,(H,25,30)(H,26,29)/t19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021640 (CHEMBL3298821) Show SMILES Fc1ccc(cc1F)-c1cc2C(=O)NCC(CC(=O)NCC3CCCCC3)n2c1 Show InChI InChI=1S/C22H25F2N3O2/c23-18-7-6-15(8-19(18)24)16-9-20-22(29)26-12-17(27(20)13-16)10-21(28)25-11-14-4-2-1-3-5-14/h6-9,13-14,17H,1-5,10-12H2,(H,25,28)(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021621 (CHEMBL3297765) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2ccnc(F)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C27H37FN6O2/c1-32-9-11-33(12-10-32)18-23(19-5-3-2-4-6-19)31-26(35)15-22-16-30-27(36)24-13-21(17-34(22)24)20-7-8-29-25(28)14-20/h7-8,13-14,17,19,22-23H,2-6,9-12,15-16,18H2,1H3,(H,30,36)(H,31,35)/t22-,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021647 (CHEMBL3298889) Show SMILES NC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1ccnc(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C22H22FN5O2/c23-20-9-15(6-7-25-20)16-8-19-22(30)26-12-17(28(19)13-16)10-21(29)27-18(11-24)14-4-2-1-3-5-14/h1-9,13,17-18H,10-12,24H2,(H,26,30)(H,27,29)/t17-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021638 (CHEMBL3298819) Show SMILES Fc1ccccc1-c1cc2C(=O)NCC(CC(=O)NCC3CCCCC3)n2c1 Show InChI InChI=1S/C22H26FN3O2/c23-19-9-5-4-8-18(19)16-10-20-22(28)25-13-17(26(20)14-16)11-21(27)24-12-15-6-2-1-3-7-15/h4-5,8-10,14-15,17H,1-3,6-7,11-13H2,(H,24,27)(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021642 (CHEMBL3298824) Show SMILES Fc1ccc(cc1F)-c1cc2C(=O)NCC(CC(=O)NCc3ccco3)n2c1 Show InChI InChI=1S/C20H17F2N3O3/c21-16-4-3-12(6-17(16)22)13-7-18-20(27)24-9-14(25(18)11-13)8-19(26)23-10-15-2-1-5-28-15/h1-7,11,14H,8-10H2,(H,23,26)(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021644 (CHEMBL3298887) Show SMILES Fc1ccc(Cl)cc1-c1cc2C(=O)NCC(CC(=O)NCc3ccco3)n2c1 Show InChI InChI=1S/C20H17ClFN3O3/c21-13-3-4-17(22)16(7-13)12-6-18-20(27)24-9-14(25(18)11-12)8-19(26)23-10-15-2-1-5-28-15/h1-7,11,14H,8-10H2,(H,23,26)(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021620 (CHEMBL3297764 | US9145418, 26) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cc(Cl)ccc2F)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H37ClFN5O2/c1-33-9-11-34(12-10-33)18-25(19-5-3-2-4-6-19)32-27(36)15-22-16-31-28(37)26-13-20(17-35(22)26)23-14-21(29)7-8-24(23)30/h7-8,13-14,17,19,22,25H,2-6,9-12,15-16,18H2,1H3,(H,31,37)(H,32,36)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021652 (CHEMBL3297758) Show SMILES OC[C@H](Cc1ccccc1)NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1 |r| Show InChI InChI=1S/C24H24FN3O3/c25-19-8-4-7-17(10-19)18-11-22-24(31)26-13-21(28(22)14-18)12-23(30)27-20(15-29)9-16-5-2-1-3-6-16/h1-8,10-11,14,20-21,29H,9,12-13,15H2,(H,26,31)(H,27,30)/t20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021617 (CHEMBL3297761) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(F)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H38FN5O2/c1-32-10-12-33(13-11-32)19-25(20-6-3-2-4-7-20)31-27(35)16-24-17-30-28(36)26-15-22(18-34(24)26)21-8-5-9-23(29)14-21/h5,8-9,14-15,18,20,24-25H,2-4,6-7,10-13,16-17,19H2,1H3,(H,30,36)(H,31,35)/t24-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021648 (CHEMBL3298890) Show SMILES NC[C@@H](NC(=O)C[C@@H]1CNC(=O)c2cc(cn12)-c1ccnc(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C22H22FN5O2/c23-20-9-15(6-7-25-20)16-8-19-22(30)26-12-17(28(19)13-16)10-21(29)27-18(11-24)14-4-2-1-3-5-14/h1-9,13,17-18H,10-12,24H2,(H,26,30)(H,27,29)/t17-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021649 (CHEMBL3298891) Show SMILES NC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C23H23FN4O2/c24-18-8-4-7-16(9-18)17-10-21-23(30)26-13-19(28(21)14-17)11-22(29)27-20(12-25)15-5-2-1-3-6-15/h1-10,14,19-20H,11-13,25H2,(H,26,30)(H,27,29)/t19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021654 (CHEMBL3297760) Show SMILES CN1CCN([C@H](C1)c1ccccc1)C(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1 |r| Show InChI InChI=1S/C26H27FN4O2/c1-29-10-11-30(24(17-29)18-6-3-2-4-7-18)25(32)14-22-15-28-26(33)23-13-20(16-31(22)23)19-8-5-9-21(27)12-19/h2-9,12-13,16,22,24H,10-11,14-15,17H2,1H3,(H,28,33)/t22-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021619 (CHEMBL3297763) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2ccc(F)c(F)c2)C2CCCCC2)CC1 |r| Show InChI InChI=1S/C28H37F2N5O2/c1-33-9-11-34(12-10-33)18-25(19-5-3-2-4-6-19)32-27(36)15-22-16-31-28(37)26-14-21(17-35(22)26)20-7-8-23(29)24(30)13-20/h7-8,13-14,17,19,22,25H,2-6,9-12,15-16,18H2,1H3,(H,31,37)(H,32,36)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021650 (CHEMBL3298892) Show SMILES OC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1)C1CCCCC1 |r| Show InChI InChI=1S/C23H28FN3O3/c24-18-8-4-7-16(9-18)17-10-21-23(30)25-12-19(27(21)13-17)11-22(29)26-20(14-28)15-5-2-1-3-6-15/h4,7-10,13,15,19-20,28H,1-3,5-6,11-12,14H2,(H,25,30)(H,26,29)/t19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021622 (CHEMBL3297767) Show SMILES CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C(C)(C)C)CC1 |r| Show InChI InChI=1S/C26H36ClN5O2/c1-26(2,3)23(17-31-10-8-30(4)9-11-31)29-24(33)14-21-15-28-25(34)22-13-19(16-32(21)22)18-6-5-7-20(27)12-18/h5-7,12-13,16,21,23H,8-11,14-15,17H2,1-4H3,(H,28,34)(H,29,33)/t21-,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021653 (CHEMBL3297759) Show SMILES NC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1)C1CCCCC1 |r| Show InChI InChI=1S/C23H29FN4O2/c24-18-8-4-7-16(9-18)17-10-21-23(30)26-13-19(28(21)14-17)11-22(29)27-20(12-25)15-5-2-1-3-6-15/h4,7-10,14-15,19-20H,1-3,5-6,11-13,25H2,(H,26,30)(H,27,29)/t19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50021625 (CHEMBL3298823) Show SMILES Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cn[nH]c2)c1 Show InChI InChI=1S/C19H18FN5O2/c20-15-3-1-2-12(4-15)7-21-18(26)6-16-10-22-19(27)17-5-13(11-25(16)17)14-8-23-24-9-14/h1-5,8-9,11,16H,6-7,10H2,(H,21,26)(H,22,27)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of CDC7 (unknown origin)				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021637 (CHEMBL3298818) Show SMILES FC(F)(F)c1cccc(c1)-c1cc2C(=O)NCC(CC(=O)NCC3CCCCC3)n2c1 Show InChI InChI=1S/C23H26F3N3O2/c24-23(25,26)18-8-4-7-16(9-18)17-10-20-22(31)28-13-19(29(20)14-17)11-21(30)27-12-15-5-2-1-3-6-15/h4,7-10,14-15,19H,1-3,5-6,11-13H2,(H,27,30)(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50021625 (CHEMBL3298823) Show SMILES Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cn[nH]c2)c1 Show InChI InChI=1S/C19H18FN5O2/c20-15-3-1-2-12(4-15)7-21-18(26)6-16-10-22-19(27)17-5-13(11-25(16)17)14-8-23-24-9-14/h1-5,8-9,11,16H,6-7,10H2,(H,21,26)(H,22,27)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin)				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021648 (CHEMBL3298890) Show SMILES NC[C@@H](NC(=O)C[C@@H]1CNC(=O)c2cc(cn12)-c1ccnc(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C22H22FN5O2/c23-20-9-15(6-7-25-20)16-8-19-22(30)26-12-17(28(19)13-16)10-21(29)27-18(11-24)14-4-2-1-3-5-14/h1-9,13,17-18H,10-12,24H2,(H,26,30)(H,27,29)/t17-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	502	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021651 (CHEMBL3298893) Show SMILES OC[C@@H](NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C23H22FN3O3/c24-18-8-4-7-16(9-18)17-10-21-23(30)25-12-19(27(21)13-17)11-22(29)26-20(14-28)15-5-2-1-3-6-15/h1-10,13,19-20,28H,11-12,14H2,(H,25,30)(H,26,29)/t19-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	516	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021632 (CHEMBL3297751) Show SMILES CC(C)(C)CNC(=O)CC1CNC(=O)c2cc(cn12)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H24F3N3O2/c1-20(2,3)12-26-18(28)9-16-10-25-19(29)17-8-14(11-27(16)17)13-5-4-6-15(7-13)21(22,23)24/h4-8,11,16H,9-10,12H2,1-3H3,(H,25,29)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	521	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021623 (CHEMBL3297768) Show SMILES C[C@@H](CN1CCN(C)CC1)NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H30ClN5O2/c1-16(14-28-8-6-27(2)7-9-28)26-22(30)12-20-13-25-23(31)21-11-18(15-29(20)21)17-4-3-5-19(24)10-17/h3-5,10-11,15-16,20H,6-9,12-14H2,1-2H3,(H,25,31)(H,26,30)/t16-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021635 (CHEMBL3298564) Show SMILES Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C23H19F4N3O2/c24-18-6-1-3-14(7-18)11-28-21(31)10-19-12-29-22(32)20-9-16(13-30(19)20)15-4-2-5-17(8-15)23(25,26)27/h1-9,13,19H,10-12H2,(H,28,31)(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	614	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021625 (CHEMBL3298823) Show SMILES Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cn[nH]c2)c1 Show InChI InChI=1S/C19H18FN5O2/c20-15-3-1-2-12(4-15)7-21-18(26)6-16-10-22-19(27)17-5-13(11-25(16)17)14-8-23-24-9-14/h1-5,8-9,11,16H,6-7,10H2,(H,21,26)(H,22,27)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	675	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021652 (CHEMBL3297758) Show SMILES OC[C@H](Cc1ccccc1)NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1 |r| Show InChI InChI=1S/C24H24FN3O3/c25-19-8-4-7-17(10-19)18-11-22-24(31)26-13-21(28(22)14-18)12-23(30)27-20(15-29)9-16-5-2-1-3-6-16/h1-8,10-11,14,20-21,29H,9,12-13,15H2,(H,26,31)(H,27,30)/t20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	684	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021636 (CHEMBL3298817) Show SMILES FC(F)(F)c1cccc(c1)-c1cc2C(=O)NCC(CC(=O)NCC3CCOCC3)n2c1 Show InChI InChI=1S/C22H24F3N3O3/c23-22(24,25)17-3-1-2-15(8-17)16-9-19-21(30)27-12-18(28(19)13-16)10-20(29)26-11-14-4-6-31-7-5-14/h1-3,8-9,13-14,18H,4-7,10-12H2,(H,26,29)(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	838	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021654 (CHEMBL3297760) Show SMILES CN1CCN([C@H](C1)c1ccccc1)C(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1 |r| Show InChI InChI=1S/C26H27FN4O2/c1-29-10-11-30(24(17-29)18-6-3-2-4-7-18)25(32)14-22-15-28-26(33)23-13-20(16-31(22)23)19-8-5-9-21(27)12-19/h2-9,12-13,16,22,24H,10-11,14-15,17H2,1H3,(H,28,33)/t22-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	956	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021643 (CHEMBL3298886) Show SMILES Clc1cccc(c1)-c1cc2C(=O)NCC(CC(=O)NCc3ccco3)n2c1 Show InChI InChI=1S/C20H18ClN3O3/c21-15-4-1-3-13(7-15)14-8-18-20(26)23-10-16(24(18)12-14)9-19(25)22-11-17-5-2-6-27-17/h1-8,12,16H,9-11H2,(H,22,25)(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021625 (CHEMBL3298823) Show SMILES Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cn[nH]c2)c1 Show InChI InChI=1S/C19H18FN5O2/c20-15-3-1-2-12(4-15)7-21-18(26)6-16-10-22-19(27)17-5-13(11-25(16)17)14-8-23-24-9-14/h1-5,8-9,11,16H,6-7,10H2,(H,21,26)(H,22,27)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021633 (CHEMBL3298562) Show SMILES CC(C)(C)CNC(=O)CC1CNC(=O)c2cc(cn12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N3O3/c1-20(2,3)12-26-18(28)9-15-10-25-19(29)17-8-14(11-27(15)17)13-5-4-6-16(7-13)30-21(22,23)24/h4-8,11,15H,9-10,12H2,1-3H3,(H,25,29)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair

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