Compile Data Set for Download or QSAR

Found 111 hits Enz. Inhib. hit(s) with all data for entry = 50017384   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181395 (1-benzyl-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pip...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C28H37N3O/c32-27(26-12-6-19-31(26)22-23-8-2-1-3-9-23)29-17-7-18-30-20-15-28(16-21-30)14-13-24-10-4-5-11-25(24)28/h1-5,8-11,26H,6-7,12-22H2,(H,29,32)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181392 ((R)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-...) Show SMILES O=C(NCCCN1CCC2(CC1)OCc1ccccc21)[C@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C27H35N3O2/c31-26(25-12-6-17-30(25)20-22-8-2-1-3-9-22)28-15-7-16-29-18-13-27(14-19-29)24-11-5-4-10-23(24)21-32-27/h1-5,8-11,25H,6-7,12-21H2,(H,28,31)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nociceptin receptor (Homo sapiens (Human))	BDBM50181395 (1-benzyl-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pip...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C28H37N3O/c32-27(26-12-6-19-31(26)22-23-8-2-1-3-9-23)29-17-7-18-30-20-15-28(16-21-30)14-13-24-10-4-5-11-25(24)28/h1-5,8-11,26H,6-7,12-22H2,(H,29,32)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181392 ((R)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-...) Show SMILES O=C(NCCCN1CCC2(CC1)OCc1ccccc21)[C@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C27H35N3O2/c31-26(25-12-6-17-30(25)20-22-8-2-1-3-9-22)28-15-7-16-29-18-13-27(14-19-29)24-11-5-4-10-23(24)21-32-27/h1-5,8-11,25H,6-7,12-21H2,(H,28,31)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nociceptin receptor (Homo sapiens (Human))	BDBM50083230 (1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...) Show SMILES CCn1c2ccccc2n([C@@H]2CCN(CC3CCCCCCC3)C[C@H]2CO)c1=O Show InChI InChI=1S/C24H37N3O2/c1-2-26-22-12-8-9-13-23(22)27(24(26)29)21-14-15-25(17-20(21)18-28)16-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-21,28H,2-7,10-11,14-18H2,1H3/t20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50083230 (1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...) Show SMILES CCn1c2ccccc2n([C@@H]2CCN(CC3CCCCCCC3)C[C@H]2CO)c1=O Show InChI InChI=1S/C24H37N3O2/c1-2-26-22-12-8-9-13-23(22)27(24(26)29)21-14-15-25(17-20(21)18-28)16-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-21,28H,2-7,10-11,14-18H2,1H3/t20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181374 (2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pi...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C29H32N2O2/c32-28(25-12-5-7-14-27(25)33-24-10-2-1-3-11-24)30-19-8-20-31-21-17-29(18-22-31)16-15-23-9-4-6-13-26(23)29/h1-7,9-14H,8,15-22H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181382 (CHEMBL199639 | N-[3-spiro(2,3-dihydro-1H-indene-1,...) Show SMILES O[C@@H](Cc1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C25H32N2O2/c28-23(19-20-7-2-1-3-8-20)24(29)26-15-6-16-27-17-13-25(14-18-27)12-11-21-9-4-5-10-22(21)25/h1-5,7-10,23,28H,6,11-19H2,(H,26,29)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181374 (2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pi...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1Oc1ccccc1 Show InChI InChI=1S/C29H32N2O2/c32-28(25-12-5-7-14-27(25)33-24-10-2-1-3-11-24)30-19-8-20-31-21-17-29(18-22-31)16-15-23-9-4-6-13-26(23)29/h1-7,9-14H,8,15-22H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181380 (CHEMBL413571 | N-[3-spiro(2,3-dihydro-1H-indene-1,...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C29H32N2O/c32-28(26-13-6-5-12-25(26)23-9-2-1-3-10-23)30-19-8-20-31-21-17-29(18-22-31)16-15-24-11-4-7-14-27(24)29/h1-7,9-14H,8,15-22H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181380 (CHEMBL413571 | N-[3-spiro(2,3-dihydro-1H-indene-1,...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C29H32N2O/c32-28(26-13-6-5-12-25(26)23-9-2-1-3-10-23)30-19-8-20-31-21-17-29(18-22-31)16-15-24-11-4-7-14-27(24)29/h1-7,9-14H,8,15-22H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181382 (CHEMBL199639 | N-[3-spiro(2,3-dihydro-1H-indene-1,...) Show SMILES O[C@@H](Cc1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C25H32N2O2/c28-23(19-20-7-2-1-3-8-20)24(29)26-15-6-16-27-17-13-25(14-18-27)12-11-21-9-4-5-10-22(21)25/h1-5,7-10,23,28H,6,11-19H2,(H,26,29)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181366 (2-benzyl-N-(3-{2,3-dihydrospiro[indene-1,4'-piperi...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1Cc1ccccc1 Show InChI InChI=1S/C30H34N2O/c33-29(27-13-6-4-12-26(27)23-24-9-2-1-3-10-24)31-19-8-20-32-21-17-30(18-22-32)16-15-25-11-5-7-14-28(25)30/h1-7,9-14H,8,15-23H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181378 ((4R)-3-benzyl-N-(3-{2,3-dihydrospiro[indene-1,4'-p...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1COC(=O)N1Cc1ccccc1 Show InChI InChI=1S/C27H33N3O3/c31-25(24-20-33-26(32)30(24)19-21-7-2-1-3-8-21)28-15-6-16-29-17-13-27(14-18-29)12-11-22-9-4-5-10-23(22)27/h1-5,7-10,24H,6,11-20H2,(H,28,31)/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181402 ((4S,5S)-4-benzyl-N-(3-{2,3-dihydrospiro[indene-1,4...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1OC(=O)N[C@H]1Cc1ccccc1 Show InChI InChI=1S/C27H33N3O3/c31-25(24-23(29-26(32)33-24)19-20-7-2-1-3-8-20)28-15-6-16-30-17-13-27(14-18-30)12-11-21-9-4-5-10-22(21)27/h1-5,7-10,23-24H,6,11-19H2,(H,28,31)(H,29,32)/t23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181379 (1-benzyl-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pip...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C28H37N3O/c32-27(26-12-6-19-31(26)22-23-8-2-1-3-9-23)29-17-7-18-30-20-15-28(16-21-30)14-13-24-10-4-5-11-25(24)28/h1-5,8-11,26H,6-7,12-22H2,(H,29,32)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181379 (1-benzyl-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pip...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C28H37N3O/c32-27(26-12-6-19-31(26)22-23-8-2-1-3-9-23)29-17-7-18-30-20-15-28(16-21-30)14-13-24-10-4-5-11-25(24)28/h1-5,8-11,26H,6-7,12-22H2,(H,29,32)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181420 ((2R)-1-benzyl-N-(3-{2,3-dihydrospiro[indene-1,4'-p...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1CCC(=O)N1Cc1ccccc1 Show InChI InChI=1S/C28H35N3O2/c32-26-12-11-25(31(26)21-22-7-2-1-3-8-22)27(33)29-17-6-18-30-19-15-28(16-20-30)14-13-23-9-4-5-10-24(23)28/h1-5,7-10,25H,6,11-21H2,(H,29,33)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181364 (2-Benzyloxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1OCc1ccccc1 Show InChI InChI=1S/C30H34N2O2/c33-29(26-12-5-7-14-28(26)34-23-24-9-2-1-3-10-24)31-19-8-20-32-21-17-30(18-22-32)16-15-25-11-4-6-13-27(25)30/h1-7,9-14H,8,15-23H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181364 (2-Benzyloxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1OCc1ccccc1 Show InChI InChI=1S/C30H34N2O2/c33-29(26-12-5-7-14-28(26)34-23-24-9-2-1-3-10-24)31-19-8-20-32-21-17-30(18-22-32)16-15-25-11-4-6-13-27(25)30/h1-7,9-14H,8,15-23H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181367 (CHEMBL380786 | benzyl (4R)-4-[(3-{2,3-dihydrospiro...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1COCN1C(=O)OCc1ccccc1 Show InChI InChI=1S/C28H35N3O4/c32-26(25-20-34-21-31(25)27(33)35-19-22-7-2-1-3-8-22)29-15-6-16-30-17-13-28(14-18-30)12-11-23-9-4-5-10-24(23)28/h1-5,7-10,25H,6,11-21H2,(H,29,32)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181403 (CHEMBL202059 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(CSc1ccccc1)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C24H30N2OS/c27-23(19-28-21-8-2-1-3-9-21)25-15-6-16-26-17-13-24(14-18-26)12-11-20-7-4-5-10-22(20)24/h1-5,7-10H,6,11-19H2,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181389 (CHEMBL202220 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1Nc1ccccc1 Show InChI InChI=1S/C29H33N3O/c33-28(25-12-5-7-14-27(25)31-24-10-2-1-3-11-24)30-19-8-20-32-21-17-29(18-22-32)16-15-23-9-4-6-13-26(23)29/h1-7,9-14,31H,8,15-22H2,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181390 (2-(1,3-benzothiazol-2-ylsulfanyl)-N-(3-{2,3-dihydr...) Show SMILES O=C(CSc1nc2ccccc2s1)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C25H29N3OS2/c29-23(18-30-24-27-21-8-3-4-9-22(21)31-24)26-14-5-15-28-16-12-25(13-17-28)11-10-19-6-1-2-7-20(19)25/h1-4,6-9H,5,10-18H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181381 (CHEMBL202604 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C(=O)c1c[nH]c2ccccc12 Show InChI InChI=1S/C26H29N3O2/c30-24(21-18-28-23-9-4-2-7-20(21)23)25(31)27-14-5-15-29-16-12-26(13-17-29)11-10-19-6-1-3-8-22(19)26/h1-4,6-9,18,28H,5,10-17H2,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181396 (CHEMBL202091 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(Cc1cccc(Oc2ccccc2)c1)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C30H34N2O2/c33-29(23-24-8-6-12-27(22-24)34-26-10-2-1-3-11-26)31-18-7-19-32-20-16-30(17-21-32)15-14-25-9-4-5-13-28(25)30/h1-6,8-13,22H,7,14-21,23H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181375 (CHEMBL426303 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(CCCc1ccccc1)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C26H34N2O/c29-25(13-6-10-22-8-2-1-3-9-22)27-18-7-19-28-20-16-26(17-21-28)15-14-23-11-4-5-12-24(23)26/h1-5,8-9,11-12H,6-7,10,13-21H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181426 (CHEMBL202094 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(CCc1c[nH]c2ccccc12)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C27H33N3O/c31-26(11-10-22-20-29-25-9-4-2-7-23(22)25)28-16-5-17-30-18-14-27(15-19-30)13-12-21-6-1-3-8-24(21)27/h1-4,6-9,20,29H,5,10-19H2,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181391 (CHEMBL425225 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)\C=C\c1ccccc1 Show InChI InChI=1S/C25H30N2O/c28-24(12-11-21-7-2-1-3-8-21)26-17-6-18-27-19-15-25(16-20-27)14-13-22-9-4-5-10-23(22)25/h1-5,7-12H,6,13-20H2,(H,26,28)/b12-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181388 (CHEMBL201694 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES OC(c1ccccc1)c1ccccc1C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C30H34N2O2/c33-28(24-10-2-1-3-11-24)25-12-5-6-13-26(25)29(34)31-19-8-20-32-21-17-30(18-22-32)16-15-23-9-4-7-14-27(23)30/h1-7,9-14,28,33H,8,15-22H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181400 (CHEMBL202575 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1(CCCCC1)c1ccccc1 Show InChI InChI=1S/C29H38N2O/c32-27(29(15-7-2-8-16-29)25-11-3-1-4-12-25)30-20-9-21-31-22-18-28(19-23-31)17-14-24-10-5-6-13-26(24)28/h1,3-6,10-13H,2,7-9,14-23H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181373 ((2E)-N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine...) Show SMILES O=C(CCc1ccccc1)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C25H32N2O/c28-24(12-11-21-7-2-1-3-8-21)26-17-6-18-27-19-15-25(16-20-27)14-13-22-9-4-5-10-23(22)25/h1-5,7-10H,6,11-20H2,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181421 (2-(4-chlorophenoxy)-N-(3-{2,3-dihydrospiro[indene-...) Show SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C26H33ClN2O2/c1-25(2,31-22-10-8-21(27)9-11-22)24(30)28-16-5-17-29-18-14-26(15-19-29)13-12-20-6-3-4-7-23(20)26/h3-4,6-11H,5,12-19H2,1-2H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181371 (CHEMBL383489 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES CC(Oc1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C25H32N2O2/c1-20(29-22-9-3-2-4-10-22)24(28)26-16-7-17-27-18-14-25(15-19-27)13-12-21-8-5-6-11-23(21)25/h2-6,8-11,20H,7,12-19H2,1H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50181395 (1-benzyl-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pip...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)[C@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C28H37N3O/c32-27(26-12-6-19-31(26)22-23-8-2-1-3-9-23)29-17-7-18-30-20-15-28(16-21-30)14-13-24-10-4-5-11-25(24)28/h1-5,8-11,26H,6-7,12-22H2,(H,29,32)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181365 (CHEMBL381240 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES COc1ccc2C(=O)C(CC(=O)NCCCN3CCC4(CCc5ccccc45)CC3)Cc2c1 Show InChI InChI=1S/C28H34N2O3/c1-33-23-7-8-24-21(18-23)17-22(27(24)32)19-26(31)29-13-4-14-30-15-11-28(12-16-30)10-9-20-5-2-3-6-25(20)28/h2-3,5-8,18,22H,4,9-17,19H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181368 (2-(2,3-dihydro-1H-inden-2-yl)-N-(3-{2,3-dihydrospi...) Show SMILES O=C(CC1Cc2ccccc2C1)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C27H34N2O/c30-26(20-21-18-23-7-1-2-8-24(23)19-21)28-14-5-15-29-16-12-27(13-17-29)11-10-22-6-3-4-9-25(22)27/h1-4,6-9,21H,5,10-20H2,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181369 (CHEMBL372353 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1CC(=O)c2ccccc12 Show InChI InChI=1S/C26H30N2O2/c29-24-18-22(20-7-2-3-8-21(20)24)25(30)27-14-5-15-28-16-12-26(13-17-28)11-10-19-6-1-4-9-23(19)26/h1-4,6-9,22H,5,10-18H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181370 (CHEMBL202438 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1Cc2ccccc2C1 Show InChI InChI=1S/C26H32N2O/c29-25(23-18-21-7-1-2-8-22(21)19-23)27-14-5-15-28-16-12-26(13-17-28)11-10-20-6-3-4-9-24(20)26/h1-4,6-9,23H,5,10-19H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181372 (CHEMBL201964 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C1(CCCC1)c1ccccc1 Show InChI InChI=1S/C28H36N2O/c31-26(28(14-6-7-15-28)24-10-2-1-3-11-24)29-19-8-20-30-21-17-27(18-22-30)16-13-23-9-4-5-12-25(23)27/h1-5,9-12H,6-8,13-22H2,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181376 (CHEMBL372774 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O[C@H](Cc1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C25H32N2O2/c28-23(19-20-7-2-1-3-8-20)24(29)26-15-6-16-27-17-13-25(14-18-27)12-11-21-9-4-5-10-22(21)25/h1-5,7-10,23,28H,6,11-19H2,(H,26,29)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181377 ((2R)-N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C29H32N2O2/c32-28(24-9-6-12-26(22-24)33-25-10-2-1-3-11-25)30-18-7-19-31-20-16-29(17-21-31)15-14-23-8-4-5-13-27(23)29/h1-6,8-13,22H,7,14-21H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181383 (CHEMBL202067 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)C(Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H36N2O/c34-30(28(26-12-5-2-6-13-26)24-25-10-3-1-4-11-25)32-20-9-21-33-22-18-31(19-23-33)17-16-27-14-7-8-15-29(27)31/h1-8,10-15,28H,9,16-24H2,(H,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181384 (CHEMBL370342 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES COC(C(=O)NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1 Show InChI InChI=1S/C25H32N2O2/c1-29-23(21-9-3-2-4-10-21)24(28)26-16-7-17-27-18-14-25(15-19-27)13-12-20-8-5-6-11-22(20)25/h2-6,8-11,23H,7,12-19H2,1H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181385 ((2Z)-N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine...) Show SMILES COc1ccccc1\C=C/C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C26H32N2O2/c1-30-24-10-5-3-8-22(24)11-12-25(29)27-17-6-18-28-19-15-26(16-20-28)14-13-21-7-2-4-9-23(21)26/h2-5,7-12H,6,13-20H2,1H3,(H,27,29)/b12-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181386 (CHEMBL372332 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(Cc1ccc2ccccc2c1)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C28H32N2O/c31-27(21-22-10-11-23-6-1-2-8-25(23)20-22)29-16-5-17-30-18-14-28(15-19-30)13-12-24-7-3-4-9-26(24)28/h1-4,6-11,20H,5,12-19,21H2,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181387 (CHEMBL201104 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES CC(NC(=O)c1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C26H33N3O2/c1-20(28-25(31)22-9-3-2-4-10-22)24(30)27-16-7-17-29-18-14-26(15-19-29)13-12-21-8-5-6-11-23(21)26/h2-6,8-11,20H,7,12-19H2,1H3,(H,27,30)(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181393 ((2S,3R)-N-(3-{2,3-dihydrospiro[indene-1,4'-piperid...) Show SMILES C[C@@H](O)[C@H](NC(=O)c1ccccc1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C27H35N3O3/c1-20(31)24(29-25(32)22-9-3-2-4-10-22)26(33)28-16-7-17-30-18-14-27(15-19-30)13-12-21-8-5-6-11-23(21)27/h2-6,8-11,20,24,31H,7,12-19H2,1H3,(H,28,33)(H,29,32)/t20-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181394 (CHEMBL202280 | N-(3-{2,3-dihydrospiro[indene-1,4'-...) Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ncccc1-c1ccccc1 Show InChI InChI=1S/C28H31N3O/c32-27(26-24(11-6-17-29-26)22-8-2-1-3-9-22)30-18-7-19-31-20-15-28(16-21-31)14-13-23-10-4-5-12-25(23)28/h1-6,8-12,17H,7,13-16,18-21H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50181398 (CHEMBL381508 | tert-butyl N-{1-[(3-{2,3-dihydrospi...) Show SMILES CC(C)(C)OC(=O)NC1(CCCCC1)C(=O)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C28H43N3O3/c1-26(2,3)34-25(33)30-28(13-7-4-8-14-28)24(32)29-18-9-19-31-20-16-27(17-21-31)15-12-22-10-5-6-11-23(22)27/h5-6,10-11H,4,7-9,12-21H2,1-3H3,(H,29,32)(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair

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