Compile Data Set for Download or QSAR

Found 64 hits Enz. Inhib. hit(s) with all data for entry = 50020613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215481 (5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(O)=O |w:12.12,8.20,TEB:17:8:13:11.10| Show InChI InChI=1S/C15H16N2O3/c1-20-9-2-3-11-10(6-9)12-8-4-5-17(7-8)14(15(18)19)13(12)16-11/h2-3,6,8,14,16H,4-5,7H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215517 (6-methoxy-2-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,...) Show SMILES COc1ccc2[nH]c3C(N(C)CCc3c2c1)C(O)=O |w:8.18| Show InChI InChI=1S/C14H16N2O3/c1-16-6-5-9-10-7-8(19-2)3-4-11(10)15-12(9)13(16)14(17)18/h3-4,7,13,15H,5-6H2,1-2H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215501 (6-(2-oxo-2-phenyl-ethoxy)-2,3,4,9-tetrahydro-1H-be...) Show SMILES OC(=O)C1NCCc2c1[nH]c1ccc(OCC(=O)c3ccccc3)cc21 Show InChI InChI=1S/C20H18N2O4/c23-17(12-4-2-1-3-5-12)11-26-13-6-7-16-15(10-13)14-8-9-21-19(20(24)25)18(14)22-16/h1-7,10,19,21-22H,8-9,11H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215502 (6-methoxy-4-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,...) Show SMILES COc1ccc2[nH]c3C(NCC(C)c3c2c1)C(O)=O |w:8.18,11.11| Show InChI InChI=1S/C14H16N2O3/c1-7-6-15-13(14(17)18)12-11(7)9-5-8(19-2)3-4-10(9)16-12/h3-5,7,13,15-16H,6H2,1-2H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215503 (4-ethyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4...) Show SMILES CCC1CNC(C(O)=O)c2[nH]c3ccc(OC)cc3c12 |w:5.5,2.1| Show InChI InChI=1S/C15H18N2O3/c1-3-8-7-16-14(15(18)19)13-12(8)10-6-9(20-2)4-5-11(10)17-13/h4-6,8,14,16-17H,3,7H2,1-2H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215483 (6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES COc1ccc2[nH]c3C(NCCc3c2c1)C(O)=O |w:8.17| Show InChI InChI=1S/C13H14N2O3/c1-18-7-2-3-10-9(6-7)8-4-5-14-12(13(16)17)11(8)15-10/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215510 (3-(hydroxymethyl)-6-methoxy-2,3,4,9-tetrahydro-1H-...) Show SMILES COc1ccc2[nH]c3C(NC(CO)Cc3c2c1)C(O)=O |w:8.19,10.10| Show InChI InChI=1S/C14H16N2O4/c1-20-8-2-3-11-9(5-8)10-4-7(6-17)15-13(14(18)19)12(10)16-11/h2-3,5,7,13,15-17H,4,6H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215506 (CHEMBL245862 | prop-2-en-1-yl 5-methoxy-9,12-diaza...) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(=O)OCC=C |w:12.12,8.20,TEB:17:8:13:11.10| Show InChI InChI=1S/C18H20N2O3/c1-3-8-23-18(21)17-16-15(11-6-7-20(17)10-11)13-9-12(22-2)4-5-14(13)19-16/h3-5,9,11,17,19H,1,6-8,10H2,2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215489 (6-hydroxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES OC(=O)C1NCCc2c1[nH]c1ccc(O)cc21 |w:3.2| Show InChI InChI=1S/C12H12N2O3/c15-6-1-2-9-8(5-6)7-3-4-13-11(12(16)17)10(7)14-9/h1-2,5,11,13-15H,3-4H2,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215497 (5-methoxy-9,12-diazatetracyclo[10.3.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCCC(C4)c3c2c1)C(O)=O |w:13.13,8.21,TEB:18:8:14:12.11.10| Show InChI InChI=1S/C16H18N2O3/c1-21-10-4-5-12-11(7-10)13-9-3-2-6-18(8-9)15(16(19)20)14(13)17-12/h4-5,7,9,15,17H,2-3,6,8H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215508 (2-ethyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4...) Show SMILES CCN1CCc2c([nH]c3ccc(OC)cc23)C1C(O)=O |w:16.19| Show InChI InChI=1S/C15H18N2O3/c1-3-17-7-6-10-11-8-9(20-2)4-5-12(11)16-13(10)14(17)15(18)19/h4-5,8,14,16H,3,6-7H2,1-2H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215523 (3-(aminomethyl)-6-methoxy-2,3,4,9-tetrahydro-1H-py...) Show SMILES COc1ccc2[nH]c3C(NC(CN)Cc3c2c1)C(O)=O |w:8.19,10.10| Show InChI InChI=1S/C14H17N3O3/c1-20-8-2-3-11-9(5-8)10-4-7(6-15)16-13(14(18)19)12(10)17-11/h2-3,5,7,13,16-17H,4,6,15H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215520 (6-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido[3...) Show SMILES COC(=O)c1ccc2[nH]c3C(NCCc3c2c1)C(O)=O |w:10.19| Show InChI InChI=1S/C14H14N2O4/c1-20-14(19)7-2-3-10-9(6-7)8-4-5-15-12(13(17)18)11(8)16-10/h2-3,6,12,15-16H,4-5H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215485 (CHEMBL245661 | benzyl 5-methoxy-9,12-diazatetracyc...) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(=O)OCc1ccccc1 |w:12.12,8.20,TEB:17:8:13:11.10| Show InChI InChI=1S/C22H22N2O3/c1-26-16-7-8-18-17(11-16)19-15-9-10-24(12-15)21(20(19)23-18)22(25)27-13-14-5-3-2-4-6-14/h2-8,11,15,21,23H,9-10,12-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215482 (6-methoxy-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,...) Show SMILES COc1ccc2[nH]c3C(NC(C)Cc3c2c1)C(O)=O |w:8.18,10.10| Show InChI InChI=1S/C14H16N2O3/c1-7-5-10-9-6-8(19-2)3-4-11(9)16-12(10)13(15-7)14(17)18/h3-4,6-7,13,15-16H,5H2,1-2H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215504 (CHEMBL245662 | propyl 5-methoxy-9,12-diazatetracyc...) Show SMILES CCCOC(=O)C1N2CCC(C2)c2c1[nH]c1ccc(OC)cc21 |w:10.10,6.5,TEB:4:6:11:9.8| Show InChI InChI=1S/C18H22N2O3/c1-3-8-23-18(21)17-16-15(11-6-7-20(17)10-11)13-9-12(22-2)4-5-14(13)19-16/h4-5,9,11,17,19H,3,6-8,10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215513 (6-(benzyloxy)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]i...) Show SMILES OC(=O)C1NCCc2c1[nH]c1ccc(OCc3ccccc3)cc21 |w:3.2| Show InChI InChI=1S/C19H18N2O3/c22-19(23)18-17-14(8-9-20-18)15-10-13(6-7-16(15)21-17)24-11-12-4-2-1-3-5-12/h1-7,10,18,20-21H,8-9,11H2,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215488 (1-phenylethyl 5-methoxy-9,12-diazatetracyclo[10.2....) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(=O)OC(C)c1ccccc1 |w:12.12,8.20,20.24,TEB:17:8:13:11.10| Show InChI InChI=1S/C23H24N2O3/c1-14(15-6-4-3-5-7-15)28-23(26)22-21-20(16-10-11-25(22)13-16)18-12-17(27-2)8-9-19(18)24-21/h3-9,12,14,16,22,24H,10-11,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215524 (4-benzyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,...) Show SMILES COc1ccc2[nH]c3C(NCC(Cc4ccccc4)c3c2c1)C(O)=O |w:8.25,11.11| Show InChI InChI=1S/C20H20N2O3/c1-25-14-7-8-16-15(10-14)17-13(9-12-5-3-2-4-6-12)11-21-19(20(23)24)18(17)22-16/h2-8,10,13,19,21-22H,9,11H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 5 (Homo sapiens (Human))	BDBM50215483 (6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES COc1ccc2[nH]c3C(NCCc3c2c1)C(O)=O |w:8.17| Show InChI InChI=1S/C13H14N2O3/c1-18-7-2-3-10-9(6-7)8-4-5-14-12(13(16)17)11(8)15-10/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PRAK				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215511 (6-chloro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole...) Show SMILES OC(=O)C1NCCc2c1[nH]c1ccc(Cl)cc21 |w:3.2| Show InChI InChI=1S/C12H11ClN2O2/c13-6-1-2-9-8(5-6)7-3-4-14-11(12(16)17)10(7)15-9/h1-2,5,11,14-15H,3-4H2,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 5 (Homo sapiens (Human))	BDBM50215481 (5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(O)=O |w:12.12,8.20,TEB:17:8:13:11.10| Show InChI InChI=1S/C15H16N2O3/c1-20-9-2-3-11-10(6-9)12-8-4-5-17(7-8)14(15(18)19)13(12)16-11/h2-3,6,8,14,16H,4-5,7H2,1H3,(H,18,19)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PRAK				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 5 (Homo sapiens (Human))	BDBM50215497 (5-methoxy-9,12-diazatetracyclo[10.3.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCCC(C4)c3c2c1)C(O)=O |w:13.13,8.21,TEB:18:8:14:12.11.10| Show InChI InChI=1S/C16H18N2O3/c1-21-10-4-5-12-11(7-10)13-9-3-2-6-18(8-9)15(16(19)20)14(13)17-12/h4-5,7,9,15,17H,2-3,6,8H2,1H3,(H,19,20)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PRAK				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215512 (6-fluoro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole...) Show SMILES OC(=O)C1NCCc2c1[nH]c1ccc(F)cc21 |w:3.2| Show InChI InChI=1S/C12H11FN2O2/c13-6-1-2-9-8(5-6)7-3-4-14-11(12(16)17)10(7)15-9/h1-2,5,11,14-15H,3-4H2,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215491 (6-carbamoyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]ind...) Show SMILES NC(=O)c1ccc2[nH]c3C(NCCc3c2c1)C(O)=O |w:9.18| Show InChI InChI=1S/C13H13N3O3/c14-12(17)6-1-2-9-8(5-6)7-3-4-15-11(13(18)19)10(7)16-9/h1-2,5,11,15-16H,3-4H2,(H2,14,17)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215492 (CHEMBL394125 | ethyl 5-methoxy-9,12-diazatetracycl...) Show SMILES CCOC(=O)C1N2CCC(C2)c2c1[nH]c1ccc(OC)cc21 |w:9.9,5.4,TEB:3:5:10:8.7| Show InChI InChI=1S/C17H20N2O3/c1-3-22-17(20)16-15-14(10-6-7-19(16)9-10)12-8-11(21-2)4-5-13(12)18-15/h4-5,8,10,16,18H,3,6-7,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215522 (5-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES COc1cccc2[nH]c3C(NCCc3c12)C(O)=O |w:9.17| Show InChI InChI=1S/C13H14N2O3/c1-18-9-4-2-3-8-10(9)7-5-6-14-12(13(16)17)11(7)15-8/h2-4,12,14-15H,5-6H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215498 (CHEMBL395132 | methyl 6-methoxy-2,3,4,9-tetrahydro...) Show SMILES COC(=O)C1NCCc2c1[nH]c1ccc(OC)cc21 |w:4.3| Show InChI InChI=1S/C14H16N2O3/c1-18-8-3-4-11-10(7-8)9-5-6-15-13(12(9)16-11)14(17)19-2/h3-4,7,13,15-16H,5-6H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215525 (7-hydroxy-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3...) Show SMILES COc1cc2c3CCNC(C(O)=O)c3[nH]c2cc1O |w:9.9| Show InChI InChI=1S/C13H14N2O4/c1-19-10-4-7-6-2-3-14-12(13(17)18)11(6)15-8(7)5-9(10)16/h4-5,12,14-16H,2-3H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215528 (3-ethyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4...) Show SMILES CCC1Cc2c([nH]c3ccc(OC)cc23)C(N1)C(O)=O |w:15.19,2.1| Show InChI InChI=1S/C15H18N2O3/c1-3-8-6-11-10-7-9(20-2)4-5-12(10)17-13(11)14(16-8)15(18)19/h4-5,7-8,14,16-17H,3,6H2,1-2H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215516 (2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carbox...) Show SMILES OC(=O)C1NCCc2c1[nH]c1ccccc21 |w:3.2| Show InChI InChI=1S/C12H12N2O2/c15-12(16)11-10-8(5-6-13-11)7-3-1-2-4-9(7)14-10/h1-4,11,13-14H,5-6H2,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215499 (CHEMBL248312 | N-hydroxy-6-methoxy-2,3,4,9-tetrahy...) Show SMILES COc1ccc2[nH]c3C(NCCc3c2c1)C(=O)NO |w:8.17| Show InChI InChI=1S/C13H15N3O3/c1-19-7-2-3-10-9(6-7)8-4-5-14-12(11(8)15-10)13(17)16-18/h2-3,6,12,14-15,18H,4-5H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 3 (Homo sapiens (Human))	BDBM50215481 (5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(O)=O |w:12.12,8.20,TEB:17:8:13:11.10| Show InChI InChI=1S/C15H16N2O3/c1-20-9-2-3-11-10(6-9)12-8-4-5-17(7-8)14(15(18)19)13(12)16-11/h2-3,6,8,14,16H,4-5,7H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK3				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50215483 (6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES COc1ccc2[nH]c3C(NCCc3c2c1)C(O)=O |w:8.17| Show InChI InChI=1S/C13H14N2O3/c1-18-7-2-3-10-9(6-7)8-4-5-14-12(13(16)17)11(8)15-10/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50215481 (5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(O)=O |w:12.12,8.20,TEB:17:8:13:11.10| Show InChI InChI=1S/C15H16N2O3/c1-20-9-2-3-11-10(6-9)12-8-4-5-17(7-8)14(15(18)19)13(12)16-11/h2-3,6,8,14,16H,4-5,7H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50215483 (6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES COc1ccc2[nH]c3C(NCCc3c2c1)C(O)=O |w:8.17| Show InChI InChI=1S/C13H14N2O3/c1-18-7-2-3-10-9(6-7)8-4-5-14-12(13(16)17)11(8)15-10/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of ERK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215521 (6-methoxy-1-(2H-tetrazol-5-yl)-2,3,4,9-tetrahydro-...) Show SMILES COc1ccc2[nH]c3C(NCCc3c2c1)c1nnn[nH]1 Show InChI InChI=1S/C13H14N6O/c1-20-7-2-3-10-9(6-7)8-4-5-14-12(11(8)15-10)13-16-18-19-17-13/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215484 (2-benzyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,...) Show SMILES COc1ccc2[nH]c3C(N(Cc4ccccc4)CCc3c2c1)C(O)=O |w:8.25| Show InChI InChI=1S/C20H20N2O3/c1-25-14-7-8-17-16(11-14)15-9-10-22(12-13-5-3-2-4-6-13)19(20(23)24)18(15)21-17/h2-8,11,19,21H,9-10,12H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 3 (Homo sapiens (Human))	BDBM50215497 (5-methoxy-9,12-diazatetracyclo[10.3.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCCC(C4)c3c2c1)C(O)=O |w:13.13,8.21,TEB:18:8:14:12.11.10| Show InChI InChI=1S/C16H18N2O3/c1-21-10-4-5-12-11(7-10)13-9-3-2-6-18(8-9)15(16(19)20)14(13)17-12/h4-5,7,9,15,17H,2-3,6,8H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK3				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215515 (6-acetoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES CC(=O)Oc1ccc2[nH]c3C(NCCc3c2c1)C(O)=O |w:10.19| Show InChI InChI=1S/C14H14N2O4/c1-7(17)20-8-2-3-11-10(6-8)9-4-5-15-13(14(18)19)12(9)16-11/h2-3,6,13,15-16H,4-5H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215527 (2-isopropyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido...) Show SMILES COc1ccc2[nH]c3C(N(CCc3c2c1)C(C)C)C(O)=O |w:8.20| Show InChI InChI=1S/C16H20N2O3/c1-9(2)18-7-6-11-12-8-10(21-3)4-5-13(12)17-14(11)15(18)16(19)20/h4-5,8-9,15,17H,6-7H2,1-3H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215514 ((6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indo...) Show SMILES COc1ccc2[nH]c3C(CN)NCCc3c2c1 |w:8.8| Show InChI InChI=1S/C13H17N3O/c1-17-8-2-3-11-10(6-8)9-4-5-15-12(7-14)13(9)16-11/h2-3,6,12,15-16H,4-5,7,14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215519 (8-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES COc1cccc2c3CCNC(C(O)=O)c3[nH]c12 |w:11.11| Show InChI InChI=1S/C13H14N2O3/c1-18-9-4-2-3-7-8-5-6-14-12(13(16)17)11(8)15-10(7)9/h2-4,12,14-15H,5-6H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215518 (CHEMBL396163 | methyl 6-methoxy-9H-pyrido[3,4-b]in...) Show SMILES COC(=O)c1nccc2c3cc(OC)ccc3[nH]c12 Show InChI InChI=1S/C14H12N2O3/c1-18-8-3-4-11-10(7-8)9-5-6-15-13(12(9)16-11)14(17)19-2/h3-7,16H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50215483 (6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES COc1ccc2[nH]c3C(NCCc3c2c1)C(O)=O |w:8.17| Show InChI InChI=1S/C13H14N2O3/c1-18-7-2-3-10-9(6-7)8-4-5-14-12(13(16)17)11(8)15-10/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of JNK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215486 ((6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indo...) Show SMILES COc1ccc2[nH]c3C(CO)NCCc3c2c1 |w:8.8| Show InChI InChI=1S/C13H16N2O2/c1-17-8-2-3-11-10(6-8)9-4-5-14-12(7-16)13(9)15-11/h2-3,6,12,14-16H,4-5,7H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215505 (2-(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]in...) Show SMILES COc1ccc2[nH]c3C(CC(O)=O)NCCc3c2c1 |w:8.8| Show InChI InChI=1S/C14H16N2O3/c1-19-8-2-3-11-10(6-8)9-4-5-15-12(7-13(17)18)14(9)16-11/h2-3,6,12,15-16H,4-5,7H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-5 (Homo sapiens (Human))	BDBM50215481 (5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(O)=O |w:12.12,8.20,TEB:17:8:13:11.10| Show InChI InChI=1S/C15H16N2O3/c1-20-9-2-3-11-10(6-9)12-8-4-5-17(7-8)14(15(18)19)13(12)16-11/h2-3,6,8,14,16H,4-5,7H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MSK1				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215493 (7-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol...) Show SMILES COc1ccc2c3CCNC(C(O)=O)c3[nH]c2c1 |w:10.10| Show InChI InChI=1S/C13H14N2O3/c1-18-7-2-3-8-9-4-5-14-12(13(16)17)11(9)15-10(8)6-7/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50215481 (5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{...) Show SMILES COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(O)=O |w:12.12,8.20,TEB:17:8:13:11.10| Show InChI InChI=1S/C15H16N2O3/c1-20-9-2-3-11-10(6-9)12-8-4-5-17(7-8)14(15(18)19)13(12)16-11/h2-3,6,8,14,16H,4-5,7H2,1H3,(H,18,19)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of IKK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 64 total )  |  Next  |  Last  >>

Jump to: