Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22000![]() (7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.100 | -56.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22001![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 0.280 | -54.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22009![]() (5-{[(1R,3R)-3-hydroxycyclopentyl]sulfanyl}-3-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.290 | -53.9 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21986![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.330 | -53.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22002![]() (5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.350 | -53.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22010![]() (5-{[(1R,3S)-3-hydroxycyclopentyl]sulfanyl}-3-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.420 | -53.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22011![]() (5-{[(1S,3R,4S)-3,4-dihydroxycyclopentyl]sulfanyl}-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.680 | -51.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22025![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-6-(1H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.790 | -51.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22014![]() (5-{[(3R)-3-hydroxypyrrolidine-1-]sulfonyl}-3-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.10 | -50.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22004![]() (3-methyl-1-(2-methylpropyl)-5-(propan-2-ylsulfanyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.20 | -48.9 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22008![]() (5-{[(1R,2R)-2-hydroxycyclopentyl]sulfanyl}-3-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.70 | -48.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22006![]() (5-(cyclopentylsulfanyl)-3-methyl-1-(2-methylpropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.20 | -48.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22020![]() (5-[(3-hydroxy-3-methylazetidin-1-yl)carbonyl]-3-me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.5 | -47.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22024![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-6-(iso...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.90 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22026![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.70 | -47.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21985![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 4.80 | -47.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22015![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.90 | -47.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22023![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5.30 | -46.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22017![]() (3-methyl-1-(2-methylpropyl)-5-(pyrrolidin-1-ylcarb...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5.5 | -46.7 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22003![]() (5-(ethylsulfanyl)-3-methyl-1-(2-methylpropyl)-6-{[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6 | -46.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22007![]() (5-(cyclohexylsulfanyl)-3-methyl-1-(2-methylpropyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6 | -46.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22012![]() (5-[(2,3-dihydroxypropyl)sulfanyl]-3-methyl-1-(2-me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6.5 | -46.3 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22027![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6.60 | -46.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22018![]() (3-methyl-1-(2-methylpropyl)-5-(piperidin-1-ylcarbo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 8.70 | -45.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22016![]() (5-(azetidin-1-ylcarbonyl)-3-methyl-1-(2-methylprop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 9.20 | -45.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22013![]() (5-{[(1R,3S)-3-hydroxycyclopentane]sulfonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 12 | -44.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22005![]() (5-(cyclobutylsulfanyl)-3-methyl-1-(2-methylpropyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 13 | -44.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22028![]() (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 16 | -44.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22029![]() (6-[(4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 26 | -42.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM22019![]() (N,N,3-trimethyl-1-(2-methylpropyl)-2,4-dioxo-6-{[2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 37 | -42.0 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183286![]() (4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-N,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183304![]() (CHEMBL380487 | N-(2-cyanoethyl)-N-ethyl-4-(1,1,1,3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183290![]() (CHEMBL205506 | pyrrolidin-1-yl-[4-(2,2,2-trifluoro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.850 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183294![]() (CHEMBL204287 | piperidin-1-yl-[4-(2,2,2-trifluoro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183287![]() (CHEMBL202688 | N-benzyl-N-methyl-4-(2,2,2-trifluor...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183328![]() (CHEMBL206852 | morpholin-4-yl-[4-(2,2,2-trifluoro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.14 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183298![]() (CHEMBL202689 | N-methoxy-N-methyl-4-(2,2,2-trifluo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.45 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183316![]() (CHEMBL202746 | N-methyl-N-phenethyl-4-(2,2,2-trifl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.99 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183313![]() (CHEMBL203835 | N-phenethyl-4-(2,2,2-trifluoro-1-hy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.65 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183307![]() (5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50212235![]() (CHEMBL400455 | N-(4-(1H-tetrazol-5-yl)butyl)-N-(4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183296![]() (5-{(morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-h...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183302![]() (CHEMBL203790 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183327![]() (CHEMBL382695 | N-(4-Cyanobutyl)-N-[4-(2,2,2-triflu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183299![]() (CHEMBL206438 | N-butyl-N-(4-(1,1,1,3,3,3-hexafluor...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183301![]() (5-{isobutyryl-[4-(2,2,2-trifluoro-1-hydroxy-1-trif...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183297![]() (CHEMBL381996 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183279![]() (CHEMBL202905 | N-butyl-N-(4-(1,1,1,3,3,3-hexafluor...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malonyl-CoA decarboxylase, mitochondrial (Homo sapiens (Human)) | BDBM50183288![]() (CHEMBL381564 | N-(4-(1,1,1,3,3,3-hexafluoro-2-hydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Chugai Pharma USA, LLC. Curated by ChEMBL | Assay Description Inhibition of MCD | J Med Chem 49: 1517-25 (2006) Article DOI: 10.1021/jm050109n BindingDB Entry DOI: 10.7270/Q2C828XZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 7 (Rattus norvegicus (Rat)) | BDBM50225551![]() (CHEMBL392378 | N-adamantan-1-ylmethyl-2-chloro-5-(...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzylATP-induced changes in plasma membrane pore formati... | J Med Chem 50: 5882-5 (2007) Article DOI: 10.1021/jm700949w BindingDB Entry DOI: 10.7270/Q2HQ3ZM9 | |||||||||||
More data for this Ligand-Target Pair |
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