Compile Data Set for Download or QSAR

Found 73 hits with Last Name = 'sides' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase beta-2 (Homo sapiens (Human))	BDBM50156461 (3-[4-(5-Aminomethyl-2-fluoro-phenyl)-piperidine-1-...) Show SMILES NCc1ccc(F)c(c1)C1CCN(CC1)C(=O)c1cc(cc(c1)-c1nc(no1)-c1cccs1)C(N)=O Show InChI InChI=1S/C26H24FN5O3S/c27-21-4-3-15(14-28)10-20(21)16-5-7-32(8-6-16)26(34)19-12-17(23(29)33)11-18(13-19)25-30-24(31-35-25)22-2-1-9-36-22/h1-4,9-13,16H,5-8,14,28H2,(H2,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human mast cell tryptase beta				Bioorg Med Chem Lett 14: 6053-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.065 BindingDB Entry DOI: 10.7270/Q2KH0MST
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50156460 (3-[4-(3-Aminomethyl-phenyl)-piperidine-1-carbonyl]...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1cc(cc(c1)-c1nc(no1)-c1cccs1)C(N)=O Show InChI InChI=1S/C26H25N5O3S/c27-15-16-3-1-4-18(11-16)17-6-8-31(9-7-17)26(33)21-13-19(23(28)32)12-20(14-21)25-29-24(30-34-25)22-5-2-10-35-22/h1-5,10-14,17H,6-9,15,27H2,(H2,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human mast cell tryptase beta				Bioorg Med Chem Lett 14: 6053-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.065 BindingDB Entry DOI: 10.7270/Q2KH0MST
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50156457 (CHEMBL186730 | [4-(5-Aminomethyl-2-fluoro-phenyl)-...) Show SMILES NCc1ccc(F)c(c1)C1CCN(CC1)C(=O)c1cccc(c1)-c1nc(no1)-c1cccs1 Show InChI InChI=1S/C25H23FN4O2S/c26-21-7-6-16(15-27)13-20(21)17-8-10-30(11-9-17)25(31)19-4-1-3-18(14-19)24-28-23(29-32-24)22-5-2-12-33-22/h1-7,12-14,17H,8-11,15,27H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human mast cell tryptase beta				Bioorg Med Chem Lett 14: 6053-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.065 BindingDB Entry DOI: 10.7270/Q2KH0MST
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167517 (CHEMBL191546 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES COCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2cccc(C)c12 Show InChI InChI=1S/C25H31N3O2/c1-18-5-3-8-22-23(17-28(24(18)22)13-14-30-2)25(29)27-11-9-20(10-12-27)21-7-4-6-19(15-21)16-26/h3-8,15,17,20H,9-14,16,26H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167534 (CHEMBL370284 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2cccc(C)c12 Show InChI InChI=1S/C24H29N3O/c1-3-26-16-22(21-9-4-6-17(2)23(21)26)24(28)27-12-10-19(11-13-27)20-8-5-7-18(14-20)15-25/h4-9,14,16,19H,3,10-13,15,25H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167531 (CHEMBL365527 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2cccc(C)c12 Show InChI InChI=1S/C25H31N3O/c1-3-12-28-17-23(22-9-4-6-18(2)24(22)28)25(29)27-13-10-20(11-14-27)21-8-5-7-19(15-21)16-26/h4-9,15,17,20H,3,10-14,16,26H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167524 (CHEMBL192963 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C25H31N3O/c1-2-3-13-28-18-23(22-9-4-5-10-24(22)28)25(29)27-14-11-20(12-15-27)21-8-6-7-19(16-21)17-26/h4-10,16,18,20H,2-3,11-15,17,26H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167525 (CHEMBL193514 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES COCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C24H29N3O2/c1-29-14-13-27-17-22(21-7-2-3-8-23(21)27)24(28)26-11-9-19(10-12-26)20-6-4-5-18(15-20)16-25/h2-8,15,17,19H,9-14,16,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50156459 (3-[4-(5-Aminomethyl-2-fluoro-phenyl)-piperidine-1-...) Show SMILES CCOC(=O)c1cc(cc(c1)-c1nc(no1)-c1cccs1)C(=O)N1CCC(CC1)c1cc(CN)ccc1F Show InChI InChI=1S/C28H27FN4O4S/c1-2-36-28(35)21-14-19(26-31-25(32-37-26)24-4-3-11-38-24)13-20(15-21)27(34)33-9-7-18(8-10-33)22-12-17(16-30)5-6-23(22)29/h3-6,11-15,18H,2,7-10,16,30H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human mast cell tryptase beta				Bioorg Med Chem Lett 14: 6053-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.065 BindingDB Entry DOI: 10.7270/Q2KH0MST
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167530 (CHEMBL189101 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES Cc1cccc2c(c[nH]c12)C(=O)N1CCC(CC1)c1cccc(CN)c1 Show InChI InChI=1S/C22H25N3O/c1-15-4-2-7-19-20(14-24-21(15)19)22(26)25-10-8-17(9-11-25)18-6-3-5-16(12-18)13-23/h2-7,12,14,17,24H,8-11,13,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167514 (CHEMBL370463 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2cccc(C)c12 Show InChI InChI=1S/C26H33N3O/c1-3-4-13-29-18-24(23-10-5-7-19(2)25(23)29)26(30)28-14-11-21(12-15-28)22-9-6-8-20(16-22)17-27/h5-10,16,18,21H,3-4,11-15,17,27H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of compound towards Factor Xa				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50156458 (3-[4-(5-Aminomethyl-2-fluoro-phenyl)-piperidine-1-...) Show SMILES NCc1ccc(F)c(c1)C1CCN(CC1)C(=O)c1cc(cc(c1)-c1nc(no1)-c1cccs1)C(O)=O Show InChI InChI=1S/C26H23FN4O4S/c27-21-4-3-15(14-28)10-20(21)16-5-7-31(8-6-16)25(32)18-11-17(12-19(13-18)26(33)34)24-29-23(30-35-24)22-2-1-9-36-22/h1-4,9-13,16H,5-8,14,28H2,(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human mast cell tryptase beta				Bioorg Med Chem Lett 14: 6053-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.065 BindingDB Entry DOI: 10.7270/Q2KH0MST
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152197 (2-[3-(5-Aminomethyl-2,4-dimethyl-benzylamino)-5-ch...) Show SMILES Cc1cc(C)c(CNc2nc(Cl)c(C)n(CC(=O)Nc3cccc(CN)c3)c2=O)cc1CN Show InChI InChI=1S/C24H29ClN6O2/c1-14-7-15(2)19(9-18(14)11-27)12-28-23-24(33)31(16(3)22(25)30-23)13-21(32)29-20-6-4-5-17(8-20)10-26/h4-9H,10-13,26-27H2,1-3H3,(H,28,30)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167520 (CHEMBL365148 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES Cc1ccc2[nH]cc(C(=O)N3CCC(CC3)c3cccc(CN)c3)c2c1 Show InChI InChI=1S/C22H25N3O/c1-15-5-6-21-19(11-15)20(14-24-21)22(26)25-9-7-17(8-10-25)18-4-2-3-16(12-18)13-23/h2-6,11-12,14,17,24H,7-10,13,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167526 (CHEMBL365189 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CC(C)Cn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C25H31N3O/c1-18(2)16-28-17-23(22-8-3-4-9-24(22)28)25(29)27-12-10-20(11-13-27)21-7-5-6-19(14-21)15-26/h3-9,14,17-18,20H,10-13,15-16,26H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167522 (CHEMBL372028 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C23H27N3O/c1-2-25-16-21(20-8-3-4-9-22(20)25)23(27)26-12-10-18(11-13-26)19-7-5-6-17(14-19)15-24/h3-9,14,16,18H,2,10-13,15,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167521 (CHEMBL364661 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCCCCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C27H35N3O/c1-2-3-4-7-15-30-20-25(24-11-5-6-12-26(24)30)27(31)29-16-13-22(14-17-29)23-10-8-9-21(18-23)19-28/h5-6,8-12,18,20,22H,2-4,7,13-17,19,28H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167511 (CHEMBL189531 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C27H27N3O3S/c28-18-20-7-6-8-22(17-20)21-13-15-29(16-14-21)27(31)25-19-30(26-12-5-4-11-24(25)26)34(32,33)23-9-2-1-3-10-23/h1-12,17,19,21H,13-16,18,28H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152198 (2-[3-(4-Amino-cyclohexylamino)-5-chloro-6-methyl-2...) Show SMILES Cc1c(Cl)nc(NC2CC[C@H](N)CC2)c(=O)n1CC(=O)Nc1cccc(CN)c1 |wU:10.10,(.97,.46,;-.37,-.31,;-1.7,.46,;-1.72,2,;-3.03,-.31,;-3.03,-1.86,;-4.39,-2.63,;-5.72,-1.86,;-5.7,-.31,;-7.03,.46,;-8.36,-.31,;-9.72,.46,;-8.39,-1.86,;-7.05,-2.63,;-1.7,-2.63,;-1.7,-4.17,;-.37,-1.86,;.97,-2.63,;2.3,-1.86,;2.3,-.31,;3.66,-2.63,;4.99,-1.86,;4.96,-.31,;6.3,.46,;7.65,-.31,;7.65,-1.86,;8.99,-2.63,;10.32,-1.86,;6.32,-2.63,)| Show InChI InChI=1S/C20H27ClN6O2/c1-12-18(21)26-19(25-15-7-5-14(23)6-8-15)20(29)27(12)11-17(28)24-16-4-2-3-13(9-16)10-22/h2-4,9,14-15H,5-8,10-11,22-23H2,1H3,(H,24,28)(H,25,26)/t14-,15?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM16127 (2,2 -methanediylbis(1H-benzimidazole-6-carboximida...) Show SMILES NC(=N)c1ccc2nc(Cc3nc4ccc(cc4[nH]3)C(N)=N)[nH]c2c1 Show InChI InChI=1S/C17H16N8/c18-16(19)8-1-3-10-12(5-8)24-14(22-10)7-15-23-11-4-2-9(17(20)21)6-13(11)25-15/h1-6H,7H2,(H3,18,19)(H3,20,21)(H,22,24)(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM16127 (2,2 -methanediylbis(1H-benzimidazole-6-carboximida...) Show SMILES NC(=N)c1ccc2nc(Cc3nc4ccc(cc4[nH]3)C(N)=N)[nH]c2c1 Show InChI InChI=1S/C17H16N8/c18-16(19)8-1-3-10-12(5-8)24-14(22-10)7-15-23-11-4-2-9(17(20)21)6-13(11)25-15/h1-6H,7H2,(H3,18,19)(H3,20,21)(H,22,24)(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167523 (CHEMBL190103 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1cn(CC2CC2)c2ccccc12 Show InChI InChI=1S/C25H29N3O/c26-15-19-4-3-5-21(14-19)20-10-12-27(13-11-20)25(29)23-17-28(16-18-8-9-18)24-7-2-1-6-22(23)24/h1-7,14,17-18,20H,8-13,15-16,26H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167535 (CHEMBL191007 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES Cn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C22H25N3O/c1-24-15-20(19-7-2-3-8-21(19)24)22(26)25-11-9-17(10-12-25)18-6-4-5-16(13-18)14-23/h2-8,13,15,17H,9-12,14,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167533 (CHEMBL435694 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CS(=O)(=O)n1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C22H25N3O3S/c1-29(27,28)25-15-20(19-7-2-3-8-21(19)25)22(26)24-11-9-17(10-12-24)18-6-4-5-16(13-18)14-23/h2-8,13,15,17H,9-12,14,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167510 (CHEMBL361040 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C24H29N3O/c1-2-12-27-17-22(21-8-3-4-9-23(21)27)24(28)26-13-10-19(11-14-26)20-7-5-6-18(15-20)16-25/h3-9,15,17,19H,2,10-14,16,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167529 (CHEMBL372912 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1cn(-c2cccnc2)c2ccccc12 Show InChI InChI=1S/C26H26N4O/c27-16-19-5-3-6-21(15-19)20-10-13-29(14-11-20)26(31)24-18-30(22-7-4-12-28-17-22)25-9-2-1-8-23(24)25/h1-9,12,15,17-18,20H,10-11,13-14,16,27H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	197	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167515 (1-{3-[4-(3-Aminomethyl-phenyl)-piperidine-1-carbon...) Show SMILES CC(=O)n1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C23H25N3O2/c1-16(27)26-15-21(20-7-2-3-8-22(20)26)23(28)25-11-9-18(10-12-25)19-6-4-5-17(13-19)14-24/h2-8,13,15,18H,9-12,14,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152202 (2-[3-(4-Amino-benzylamino)-5-chloro-6-methyl-2-oxo...) Show SMILES Cc1c(Cl)nc(NCc2ccc(N)cc2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C21H23ClN6O2/c1-13-19(22)27-20(25-11-14-5-7-16(24)8-6-14)21(30)28(13)12-18(29)26-17-4-2-3-15(9-17)10-23/h2-9H,10-12,23-24H2,1H3,(H,25,27)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167513 (CHEMBL192214 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1cn(C(=O)c2cccs2)c2ccccc12 Show InChI InChI=1S/C26H25N3O2S/c27-16-18-5-3-6-20(15-18)19-10-12-28(13-11-19)25(30)22-17-29(23-8-2-1-7-21(22)23)26(31)24-9-4-14-32-24/h1-9,14-15,17,19H,10-13,16,27H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152200 (CHEMBL183528 | N-(3-Aminomethyl-phenyl)-2-{5-chlor...) Show SMILES Cc1c(Cl)nc(NCC2CCNCC2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C20H27ClN6O2/c1-13-18(21)26-19(24-11-14-5-7-23-8-6-14)20(29)27(13)12-17(28)25-16-4-2-3-15(9-16)10-22/h2-4,9,14,23H,5-8,10-12,22H2,1H3,(H,24,26)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167528 (CHEMBL436537 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1c[nH]c2ccccc12 Show InChI InChI=1S/C21H23N3O/c22-13-15-4-3-5-17(12-15)16-8-10-24(11-9-16)21(25)19-14-23-20-7-2-1-6-18(19)20/h1-7,12,14,16,23H,8-11,13,22H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167519 (CHEMBL190135 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CC(C)n1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2ccccc12 Show InChI InChI=1S/C24H29N3O/c1-17(2)27-16-22(21-8-3-4-9-23(21)27)24(28)26-12-10-19(11-13-26)20-7-5-6-18(14-20)15-25/h3-9,14,16-17,19H,10-13,15,25H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167527 (CHEMBL189983 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1c[nH]c2c(F)cccc12 Show InChI InChI=1S/C21H22FN3O/c22-19-6-2-5-17-18(13-24-20(17)19)21(26)25-9-7-15(8-10-25)16-4-1-3-14(11-16)12-23/h1-6,11,13,15,24H,7-10,12,23H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	368	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167518 (CHEMBL189372 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1cn(-c2nccs2)c2ccccc12 Show InChI InChI=1S/C24H24N4OS/c25-15-17-4-3-5-19(14-17)18-8-11-27(12-9-18)23(29)21-16-28(24-26-10-13-30-24)22-7-2-1-6-20(21)22/h1-7,10,13-14,16,18H,8-9,11-12,15,25H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	373	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152205 (2-[3-(3-Aminomethyl-benzylamino)-5-chloro-6-methyl...) Show SMILES Cc1c(Cl)nc(NCc2cccc(CN)c2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C22H25ClN6O2/c1-14-20(23)28-21(26-12-17-6-2-4-15(8-17)10-24)22(31)29(14)13-19(30)27-18-7-3-5-16(9-18)11-25/h2-9H,10-13,24-25H2,1H3,(H,26,28)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152206 (CHEMBL187587 | N-(3-Aminomethyl-phenyl)-2-{5-chlor...) Show SMILES Cc1c(Cl)nc(NCCc2cnc[nH]2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C19H22ClN7O2/c1-12-17(20)26-18(23-6-5-15-9-22-11-24-15)19(29)27(12)10-16(28)25-14-4-2-3-13(7-14)8-21/h2-4,7,9,11H,5-6,8,10,21H2,1H3,(H,22,24)(H,23,26)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	426	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167516 (CHEMBL191731 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1cn(CC2CCCCC2)c2ccccc12 Show InChI InChI=1S/C28H35N3O/c29-18-22-9-6-10-24(17-22)23-13-15-30(16-14-23)28(32)26-20-31(19-21-7-2-1-3-8-21)27-12-5-4-11-25(26)27/h4-6,9-12,17,20-21,23H,1-3,7-8,13-16,18-19,29H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	497	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152196 (CHEMBL184815 | N-(3-Aminomethyl-phenyl)-2-{5-chlor...) Show SMILES Cc1c(Cl)nc(NCC2CCCNC2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C20H27ClN6O2/c1-13-18(21)26-19(24-11-15-5-3-7-23-10-15)20(29)27(13)12-17(28)25-16-6-2-4-14(8-16)9-22/h2,4,6,8,15,23H,3,5,7,9-12,22H2,1H3,(H,24,26)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	518	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152193 (CHEMBL187649 | N-(3-Aminomethyl-phenyl)-2-{3-[(6-a...) Show SMILES Cc1nc(N)ccc1CNc1nc(Cl)c(C)n(CC(=O)Nc2cccc(CN)c2)c1=O Show InChI InChI=1S/C21H24ClN7O2/c1-12-15(6-7-17(24)26-12)10-25-20-21(31)29(13(2)19(22)28-20)11-18(30)27-16-5-3-4-14(8-16)9-23/h3-8H,9-11,23H2,1-2H3,(H2,24,26)(H,25,28)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152203 (2-[3-(4-Aminomethyl-benzylamino)-5-chloro-6-methyl...) Show SMILES Cc1c(Cl)nc(NCc2ccc(CN)cc2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C22H25ClN6O2/c1-14-20(23)28-21(26-12-16-7-5-15(10-24)6-8-16)22(31)29(14)13-19(30)27-18-4-2-3-17(9-18)11-25/h2-9H,10-13,24-25H2,1H3,(H,26,28)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	615	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152194 (2-[3-(2-Amino-benzylamino)-5-chloro-6-methyl-2-oxo...) Show SMILES Cc1c(Cl)nc(NCc2ccccc2N)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C21H23ClN6O2/c1-13-19(22)27-20(25-11-15-6-2-3-8-17(15)24)21(30)28(13)12-18(29)26-16-7-4-5-14(9-16)10-23/h2-9H,10-12,23-24H2,1H3,(H,25,27)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	875	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152204 (CHEMBL360210 | N-(3-Aminomethyl-phenyl)-2-[5-chlor...) Show SMILES Cc1c(Cl)nc(NC2Cc3ccccc3C2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C23H24ClN5O2/c1-14-21(24)28-22(27-19-10-16-6-2-3-7-17(16)11-19)23(31)29(14)13-20(30)26-18-8-4-5-15(9-18)12-25/h2-9,19H,10-13,25H2,1H3,(H,26,30)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152195 (CHEMBL187168 | N-(3-Aminomethyl-phenyl)-2-[3-(4-be...) Show SMILES Cc1c(Cl)nc(N2CCC(CC2)n2cnc3ccccc23)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C26H28ClN7O2/c1-17-24(27)31-25(26(36)33(17)15-23(35)30-19-6-4-5-18(13-19)14-28)32-11-9-20(10-12-32)34-16-29-21-7-2-3-8-22(21)34/h2-8,13,16,20H,9-12,14-15,28H2,1H3,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152201 (CHEMBL187651 | N-(3-Aminomethyl-phenyl)-2-[5-chlor...) Show SMILES COc1ccc(CNc2nc(Cl)c(C)n(CC(=O)Nc3cccc(CN)c3)c2=O)cc1 Show InChI InChI=1S/C22H24ClN5O3/c1-14-20(23)27-21(25-12-15-6-8-18(31-2)9-7-15)22(30)28(14)13-19(29)26-17-5-3-4-16(10-17)11-24/h3-10H,11-13,24H2,1-2H3,(H,25,27)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152199 (CHEMBL183942 | N-(3-Aminomethyl-phenyl)-2-(5-chlor...) Show SMILES Cc1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C22H24ClN5O2/c1-15-20(23)27-21(25-11-10-16-6-3-2-4-7-16)22(30)28(15)14-19(29)26-18-9-5-8-17(12-18)13-24/h2-9,12H,10-11,13-14,24H2,1H3,(H,25,27)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167532 (CHEMBL191072 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES Cc1cccc2[nH]cc(C(=O)N3CCC(CC3)c3cccc(CN)c3)c12 Show InChI InChI=1S/C22H25N3O/c1-15-4-2-7-20-21(15)19(14-24-20)22(26)25-10-8-17(9-11-25)18-6-3-5-16(12-18)13-23/h2-7,12,14,17,24H,8-11,13,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167512 (CHEMBL188104 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES Cc1ccc2c(c[nH]c2c1)C(=O)N1CCC(CC1)c1cccc(CN)c1 Show InChI InChI=1S/C22H25N3O/c1-15-5-6-19-20(14-24-21(19)11-15)22(26)25-9-7-17(8-10-25)18-4-2-3-16(12-18)13-23/h2-6,11-12,14,17,24H,7-10,13,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167514 (CHEMBL370463 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES CCCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2cccc(C)c12 Show InChI InChI=1S/C26H33N3O/c1-3-4-13-29-18-24(23-10-5-7-19(2)25(23)29)26(30)28-14-11-21(12-15-28)22-9-6-8-20(16-22)17-27/h5-10,16,18,21H,3-4,11-15,17,27H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against Factor Xa				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50156457 (CHEMBL186730 | [4-(5-Aminomethyl-2-fluoro-phenyl)-...) Show SMILES NCc1ccc(F)c(c1)C1CCN(CC1)C(=O)c1cccc(c1)-c1nc(no1)-c1cccs1 Show InChI InChI=1S/C25H23FN4O2S/c26-21-7-6-16(15-27)13-20(21)17-8-10-30(11-9-17)25(31)19-4-1-3-18(14-19)24-28-23(29-32-24)22-5-2-12-33-22/h1-7,12-14,17H,8-11,15,27H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against cytochrome P450 determined using human liver microsome upon 15 min incubation with probes substrates tolbutamide (2C9)				Bioorg Med Chem Lett 14: 6053-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.065 BindingDB Entry DOI: 10.7270/Q2KH0MST
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50156457 (CHEMBL186730 | [4-(5-Aminomethyl-2-fluoro-phenyl)-...) Show SMILES NCc1ccc(F)c(c1)C1CCN(CC1)C(=O)c1cccc(c1)-c1nc(no1)-c1cccs1 Show InChI InChI=1S/C25H23FN4O2S/c26-21-7-6-16(15-27)13-20(21)17-8-10-30(11-9-17)25(31)19-4-1-3-18(14-19)24-28-23(29-32-24)22-5-2-12-33-22/h1-7,12-14,17H,8-11,15,27H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Potassium channel HERG				Bioorg Med Chem Lett 14: 6053-6 (2004) Article DOI: 10.1016/j.bmcl.2004.09.065 BindingDB Entry DOI: 10.7270/Q2KH0MST
					More data for this Ligand-Target Pair

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