Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159550 (CHEMBL3785336) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159533 (CHEMBL3786653) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159548 (CHEMBL3785750) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159554 (CHEMBL3787085) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159545 (CHEMBL3785828) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159556 (CHEMBL3785219) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50323654 (CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159547 (CHEMBL3786659) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159551 (CHEMBL3786730) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159553 (CHEMBL3785530) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159529 (CHEMBL3787449) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159532 (CHEMBL3786485) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159555 (CHEMBL3787277) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159546 (CHEMBL3786591) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159549 (CHEMBL3786247) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Scavenger receptor class B member 1 (Homo sapiens (Human)) | BDBM50159558 (CHEMBL3786009) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me... | Bioorg Med Chem Lett 26: 1901-4 (2016) Article DOI: 10.1016/j.bmcl.2016.03.025 BindingDB Entry DOI: 10.7270/Q22R3TJ2 | |||||||||||
More data for this Ligand-Target Pair |