Compile Data Set for Download or QSAR

Found 349 hits with Last Name = 'kanesaka' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296171 (1-{3-[4-((2S,3S)-8-Methoxy-3-methyl-4,4-dioxo-3,4-...) Show SMILES COc1cccc2c1O[C@H]([C@H](C)S2(=O)=O)c1ccc(OCCCN2CCCC2)cc1 |r| Show InChI InChI=1S/C23H29NO5S/c1-17-22(29-23-20(27-2)7-5-8-21(23)30(17,25)26)18-9-11-19(12-10-18)28-16-6-15-24-13-3-4-14-24/h5,7-12,17,22H,3-4,6,13-16H2,1-2H3/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]R-alpha-methylistamine from human histamine H3 receptor by cell-based assay				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50296171 (1-{3-[4-((2S,3S)-8-Methoxy-3-methyl-4,4-dioxo-3,4-...) Show SMILES COc1cccc2c1O[C@H]([C@H](C)S2(=O)=O)c1ccc(OCCCN2CCCC2)cc1 |r| Show InChI InChI=1S/C23H29NO5S/c1-17-22(29-23-20(27-2)7-5-8-21(23)30(17,25)26)18-9-11-19(12-10-18)28-16-6-15-24-13-3-4-14-24/h5,7-12,17,22H,3-4,6,13-16H2,1-2H3/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]R-alpha-methylistamine from rat histamine H3 receptor by cell-based assay				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mus musculus)	BDBM50296171 (1-{3-[4-((2S,3S)-8-Methoxy-3-methyl-4,4-dioxo-3,4-...) Show SMILES COc1cccc2c1O[C@H]([C@H](C)S2(=O)=O)c1ccc(OCCCN2CCCC2)cc1 |r| Show InChI InChI=1S/C23H29NO5S/c1-17-22(29-23-20(27-2)7-5-8-21(23)30(17,25)26)18-9-11-19(12-10-18)28-16-6-15-24-13-3-4-14-24/h5,7-12,17,22H,3-4,6,13-16H2,1-2H3/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]R-alpha-methylistamine from mouse histamine H3 receptor by cell-based assay				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296179 ((+/-)-1-Cyclobutyl-4-[4-(8-methoxy-3-methyl-4,4-di...) Show SMILES COc1cccc2c1OC(C(C)S2(=O)=O)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C25H31NO5S/c1-17-24(31-25-22(29-2)7-4-8-23(25)32(17,27)28)18-9-11-20(12-10-18)30-21-13-15-26(16-14-21)19-5-3-6-19/h4,7-12,17,19,21,24H,3,5-6,13-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296178 ((+/-)-(S)-1-{3-[4-(8-Methoxy-3-methyl-4,4-dioxo-3,...) Show SMILES COc1cccc2c1OC(C(C)S2(=O)=O)c1ccc(OCCCN2CCC[C@H](C)C2)cc1 |r| Show InChI InChI=1S/C25H33NO5S/c1-18-7-5-14-26(17-18)15-6-16-30-21-12-10-20(11-13-21)24-19(2)32(27,28)23-9-4-8-22(29-3)25(23)31-24/h4,8-13,18-19,24H,5-7,14-17H2,1-3H3/t18-,19?,24?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296176 ((+/-)-(R)-1-{3-[4-(8-Methoxy-3-methyl-4,4-dioxo-3,...) Show SMILES COc1cccc2c1OC(C(C)S2(=O)=O)c1ccc(OCCCN2CCC[C@H]2C)cc1 |r| Show InChI InChI=1S/C24H31NO5S/c1-17-7-5-14-25(17)15-6-16-29-20-12-10-19(11-13-20)23-18(2)31(26,27)22-9-4-8-21(28-3)24(22)30-23/h4,8-13,17-18,23H,5-7,14-16H2,1-3H3/t17-,18?,23?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296174 ((+/-)-1-{3-[4-(7-Methoxy-3-methyl-4,4-dioxo-3,4-di...) Show SMILES COc1ccc2c(OC(C(C)S2(=O)=O)c2ccc(OCCCN3CCCC3)cc2)c1 Show InChI InChI=1S/C23H29NO5S/c1-17-23(29-21-16-20(27-2)10-11-22(21)30(17,25)26)18-6-8-19(9-7-18)28-15-5-14-24-12-3-4-13-24/h6-11,16-17,23H,3-5,12-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296175 ((+/-)-1-{3-[4-(8-Methoxy-3-methyl-4,4-dioxo-3,4-di...) Show SMILES COc1cccc2c1OC(C(C)S2(=O)=O)c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C24H31NO5S/c1-18-23(30-24-21(28-2)8-6-9-22(24)31(18,26)27)19-10-12-20(13-11-19)29-17-7-16-25-14-4-3-5-15-25/h6,8-13,18,23H,3-5,7,14-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296171 (1-{3-[4-((2S,3S)-8-Methoxy-3-methyl-4,4-dioxo-3,4-...) Show SMILES COc1cccc2c1O[C@H]([C@H](C)S2(=O)=O)c1ccc(OCCCN2CCCC2)cc1 |r| Show InChI InChI=1S/C23H29NO5S/c1-17-22(29-23-20(27-2)7-5-8-21(23)30(17,25)26)18-9-11-19(12-10-18)28-16-6-15-24-13-3-4-14-24/h5,7-12,17,22H,3-4,6,13-16H2,1-2H3/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296173 ((+/-)-1-{3-[4-(6-Methoxy-3-methyl-4,4-dioxo-3,4-di...) Show SMILES COc1ccc2OC(C(C)S(=O)(=O)c2c1)c1ccc(OCCCN2CCCC2)cc1 Show InChI InChI=1S/C23H29NO5S/c1-17-23(29-21-11-10-20(27-2)16-22(21)30(17,25)26)18-6-8-19(9-7-18)28-15-5-14-24-12-3-4-13-24/h6-11,16-17,23H,3-5,12-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296171 (1-{3-[4-((2S,3S)-8-Methoxy-3-methyl-4,4-dioxo-3,4-...) Show SMILES COc1cccc2c1O[C@H]([C@H](C)S2(=O)=O)c1ccc(OCCCN2CCCC2)cc1 |r| Show InChI InChI=1S/C23H29NO5S/c1-17-22(29-23-20(27-2)7-5-8-21(23)30(17,25)26)18-9-11-19(12-10-18)28-16-6-15-24-13-3-4-14-24/h5,7-12,17,22H,3-4,6,13-16H2,1-2H3/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296172 ((+/-)-1-{3-[4-(5-Methoxy-3-methyl-4,4-dioxo-3,4-di...) Show SMILES COc1cccc2OC(C(C)S(=O)(=O)c12)c1ccc(OCCCN2CCCC2)cc1 Show InChI InChI=1S/C23H29NO5S/c1-17-22(29-21-8-5-7-20(27-2)23(21)30(17,25)26)18-9-11-19(12-10-18)28-16-6-15-24-13-3-4-14-24/h5,7-12,17,22H,3-4,6,13-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296188 (CHEMBL558248 | trans-1-{3-[4-(3-Methyl-4,4-dioxo-3...) Show SMILES C[C@@H]1[C@H](Oc2ccccc2S1(=O)=O)c1ccc(OCCCN2CCCC2)cc1 |r| Show InChI InChI=1S/C22H27NO4S/c1-17-22(27-20-7-2-3-8-21(20)28(17,24)25)18-9-11-19(12-10-18)26-16-6-15-23-13-4-5-14-23/h2-3,7-12,17,22H,4-6,13-16H2,1H3/t17-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296181 ((+/-)-1-{3-[4-(3-Methyl-4,4-dioxo-3,4-dihydro-2H-4...) Show SMILES CC1C(Oc2ccccc2S1(=O)=O)c1ccc(OCCCN2CCCC2)cc1 Show InChI InChI=1S/C22H27NO4S/c1-17-22(27-20-7-2-3-8-21(20)28(17,24)25)18-9-11-19(12-10-18)26-16-6-15-23-13-4-5-14-23/h2-3,7-12,17,22H,4-6,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296180 (1-{3-[4-((2R,3R)-8-Methoxy-3-methyl-4,4-dioxo-3,4-...) Show SMILES COc1cccc2c1O[C@@H]([C@@H](C)S2(=O)=O)c1ccc(OCCCN2CCCC2)cc1 |r| Show InChI InChI=1S/C23H29NO5S/c1-17-22(29-23-20(27-2)7-5-8-21(23)30(17,25)26)18-9-11-19(12-10-18)28-16-6-15-24-13-3-4-14-24/h5,7-12,17,22H,3-4,6,13-16H2,1-2H3/t17-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.607	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296177 ((+/-)-(S)-1-{3-[4-(8-Methoxy-3-methyl-4,4-dioxo-3,...) Show SMILES COc1cccc2c1OC(C(C)S2(=O)=O)c1ccc(OCCCN2CCC[C@@H]2C)cc1 |r| Show InChI InChI=1S/C24H31NO5S/c1-17-7-5-14-25(17)15-6-16-29-20-12-10-19(11-13-20)23-18(2)31(26,27)22-9-4-8-21(28-3)24(22)30-23/h4,8-13,17-18,23H,5-7,14-16H2,1-3H3/t17-,18?,23?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296189 (1-{3-[4-(3-Methyl-4,4-dioxo-4H-4lambda*6*-benzo[1,...) Show SMILES CC1=C(Oc2ccccc2S1(=O)=O)c1ccc(OCCCN2CCCC2)cc1 |t:1| Show InChI InChI=1S/C22H25NO4S/c1-17-22(27-20-7-2-3-8-21(20)28(17,24)25)18-9-11-19(12-10-18)26-16-6-15-23-13-4-5-14-23/h2-3,7-12H,4-6,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304315 (CHEMBL593465 | trans-3-Oxo-N-(2-phenyl-2H-1,2,3-tr...) Show SMILES O=C(Nc1cnn(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(-4.09,-21.75,;-3.32,-23.08,;-1.78,-23.08,;-.88,-24.33,;.67,-24.33,;1.14,-25.79,;-.1,-26.7,;-1.35,-25.79,;-.1,-28.23,;-1.44,-29,;-1.44,-30.53,;-.11,-31.31,;1.23,-30.53,;1.23,-28.99,;-4.09,-24.41,;-5.63,-24.41,;-6.41,-25.75,;-5.63,-27.07,;-4.09,-27.07,;-3.33,-25.75,;-4.71,-28.33,;-5.62,-29.59,;-5.15,-31.05,;-7.1,-29.11,;-8.43,-29.88,;-9.77,-29.11,;-9.76,-27.56,;-8.43,-26.79,;-7.1,-27.56,)| Show InChI InChI=1S/C21H19N5O3/c27-19(24-18-13-23-26(25-18)15-4-2-1-3-5-15)14-6-9-21(10-7-14)17-12-22-11-8-16(17)20(28)29-21/h1-5,8,11-14H,6-7,9-10H2,(H,24,25,27)/t14-,21-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.890	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304301 (CHEMBL595790 | trans-N-[1-(3-Fluorophenyl)-1H-pyra...) Show SMILES Fc1ccc(cc1)-n1ccc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)n1 |r,wU:17.21,wD:14.14,(.68,-45.87,;.68,-44.33,;-.66,-43.55,;-.65,-42.02,;.68,-41.25,;2.01,-42.01,;2.02,-43.55,;.68,-39.72,;1.93,-38.81,;1.45,-37.35,;-.09,-37.35,;-.99,-36.1,;-2.53,-36.1,;-3.3,-34.77,;-3.31,-37.43,;-4.85,-37.43,;-5.62,-38.77,;-4.85,-40.09,;-3.31,-40.09,;-2.54,-38.77,;-3.93,-41.35,;-4.84,-42.61,;-4.36,-44.07,;-6.31,-42.13,;-7.65,-42.9,;-8.98,-42.13,;-8.98,-40.58,;-7.65,-39.81,;-6.31,-40.58,;-.56,-38.81,)| Show InChI InChI=1S/C22H19FN4O3/c23-15-1-3-16(4-2-15)27-12-8-19(26-27)25-20(28)14-5-9-22(10-6-14)18-13-24-11-7-17(18)21(29)30-22/h1-4,7-8,11-14H,5-6,9-10H2,(H,25,26,28)/t14-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304313 (CHEMBL607037 | trans-3-Oxo-N-(2-phenyl-1,3-thiazol...) Show SMILES O=C(Nc1csc(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(-3.64,-7.7,;-2.87,-9.03,;-1.33,-9.04,;-.39,-10.26,;1.15,-10.22,;1.66,-11.67,;.44,-12.61,;-.83,-11.74,;.48,-14.15,;-.83,-14.95,;-.79,-16.49,;.56,-17.22,;1.88,-16.41,;1.83,-14.88,;-3.64,-10.37,;-5.18,-10.37,;-5.95,-11.7,;-5.18,-13.03,;-3.64,-13.03,;-2.87,-11.7,;-4.26,-14.29,;-5.17,-15.54,;-4.7,-17.01,;-6.65,-15.06,;-7.98,-15.83,;-9.31,-15.06,;-9.31,-13.52,;-7.98,-12.75,;-6.65,-13.51,)| Show InChI InChI=1S/C22H19N3O3S/c26-19(24-18-13-29-20(25-18)15-4-2-1-3-5-15)14-6-9-22(10-7-14)17-12-23-11-8-16(17)21(27)28-22/h1-5,8,11-14H,6-7,9-10H2,(H,24,26)/t14-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50265209 (1'-(5-chloro-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...) Show SMILES Clc1ccc2nc([nH]c2c1)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C19H16ClN3O2/c20-12-5-6-15-16(11-12)22-18(21-15)23-9-7-19(8-10-23)14-4-2-1-3-13(14)17(24)25-19/h1-6,11H,7-10H2,(H,21,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...				Bioorg Med Chem Lett 18: 5010-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.018 BindingDB Entry DOI: 10.7270/Q26D5STS
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304298 (CHEMBL595120 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1cnn(c1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21 |r,wU:17.22,wD:14.15,(-4.96,-20.66,;-4.19,-21.99,;-2.65,-21.99,;-1.77,-23.26,;-.23,-23.29,;.22,-24.77,;-1.05,-25.64,;-2.28,-24.71,;-1.08,-27.17,;-2.44,-27.91,;-2.47,-29.45,;-1.16,-30.25,;.2,-29.51,;.23,-27.97,;-4.96,-23.32,;-6.5,-23.32,;-7.28,-24.66,;-6.5,-25.99,;-4.96,-25.99,;-4.2,-24.66,;-5.58,-27.24,;-6.49,-28.5,;-6.02,-29.96,;-7.97,-28.02,;-9.3,-28.79,;-10.64,-28.02,;-10.63,-26.48,;-9.31,-25.7,;-7.97,-26.47,)| Show InChI InChI=1S/C22H20N4O3/c27-20(25-16-13-24-26(14-16)17-5-2-1-3-6-17)15-8-10-22(11-9-15)18-7-4-12-23-19(18)21(28)29-22/h1-7,12-15H,8-11H2,(H,25,27)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304300 (CHEMBL595573 | trans-N-[1-(2-fluorophenyl)-3-pyraz...) Show SMILES Fc1ccccc1-n1ccc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)n1 |r,wU:17.21,wD:14.14,(16.87,-28.98,;15.54,-29.75,;15.54,-31.28,;14.2,-32.06,;12.87,-31.29,;12.87,-29.75,;14.21,-28.98,;14.21,-27.45,;15.45,-26.55,;14.98,-25.08,;13.44,-25.08,;12.53,-23.84,;10.99,-23.84,;10.22,-22.5,;10.22,-25.17,;8.68,-25.17,;7.91,-26.5,;8.68,-27.83,;10.22,-27.83,;10.99,-26.5,;9.6,-29.09,;8.69,-30.34,;9.16,-31.81,;7.21,-29.86,;5.88,-30.63,;4.55,-29.86,;4.55,-28.32,;5.88,-27.55,;7.21,-28.31,;12.96,-26.54,)| Show InChI InChI=1S/C22H19FN4O3/c23-17-3-1-2-4-18(17)27-12-8-19(26-27)25-20(28)14-5-9-22(10-6-14)16-13-24-11-7-15(16)21(29)30-22/h1-4,7-8,11-14H,5-6,9-10H2,(H,25,26,28)/t14-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50264726 (1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...) Show SMILES Clc1cc2nc([nH]c2cc1Cl)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C19H15Cl2N3O2/c20-13-9-15-16(10-14(13)21)23-18(22-15)24-7-5-19(6-8-24)12-4-2-1-3-11(12)17(25)26-19/h1-4,9-10H,5-8H2,(H,22,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...				Bioorg Med Chem Lett 18: 5010-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.018 BindingDB Entry DOI: 10.7270/Q26D5STS
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50265298 (CHEMBL496327 | methyl 2-(3-oxo-3H-spiro[isobenzofu...) Show SMILES COC(=O)c1ccc2nc([nH]c2c1)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C21H19N3O4/c1-27-18(25)13-6-7-16-17(12-13)23-20(22-16)24-10-8-21(9-11-24)15-5-3-2-4-14(15)19(26)28-21/h2-7,12H,8-11H2,1H3,(H,22,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...				Bioorg Med Chem Lett 18: 5010-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.018 BindingDB Entry DOI: 10.7270/Q26D5STS
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304303 (CHEMBL593934 | trans-3-Oxo-N-(5-phenylpyrazin-2-yl...) Show SMILES O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21 |r,wU:18.23,wD:15.16,(-4.29,5.75,;-3.52,4.41,;-1.98,4.41,;-1.21,3.08,;-1.99,1.75,;-1.22,.41,;.32,.41,;1.09,1.75,;.32,3.08,;1.09,-.92,;.32,-2.25,;1.08,-3.58,;2.63,-3.58,;3.4,-2.24,;2.62,-.91,;-4.29,3.08,;-5.83,3.08,;-6.61,1.75,;-5.83,.42,;-4.29,.42,;-3.53,1.75,;-4.91,-.84,;-5.83,-2.09,;-5.35,-3.56,;-7.3,-1.61,;-8.63,-2.39,;-9.97,-1.61,;-9.97,-.07,;-8.64,.7,;-7.3,-.06,)| Show InChI InChI=1S/C24H21N3O3/c28-22(27-21-15-25-20(14-26-21)16-6-2-1-3-7-16)17-10-12-24(13-11-17)19-9-5-4-8-18(19)23(29)30-24/h1-9,14-15,17H,10-13H2,(H,26,27,28)/t17-,24-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50264726 (1'-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-3H-spir...) Show SMILES Clc1cc2nc([nH]c2cc1Cl)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C19H15Cl2N3O2/c20-13-9-15-16(10-14(13)21)23-18(22-15)24-7-5-19(6-8-24)12-4-2-1-3-11(12)17(25)26-19/h1-4,9-10H,5-8H2,(H,22,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cells				Bioorg Med Chem Lett 18: 5010-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.018 BindingDB Entry DOI: 10.7270/Q26D5STS
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50264364 (CHEMBL491229 | trans-4-[5-(4-Fluoro-phenyl)-1H-ben...) Show SMILES Fc1ccc(cc1)-c1ccc2nc([nH]c2c1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21 |r,wU:19.25,wD:16.18,(9.47,-34.56,;8.18,-35.41,;8.26,-36.94,;6.98,-37.78,;5.61,-37.08,;5.52,-35.55,;6.8,-34.71,;4.32,-37.92,;4.41,-39.46,;3.12,-40.29,;1.76,-39.59,;.32,-40.15,;-.65,-38.94,;.19,-37.66,;1.68,-38.06,;2.96,-37.23,;-2.18,-39.02,;-3.02,-37.72,;-4.57,-37.81,;-5.27,-39.18,;-4.43,-40.48,;-2.89,-40.4,;-5.97,-40.56,;-7.5,-40.32,;-8.59,-41.4,;-7.74,-38.79,;-9.03,-37.95,;-8.95,-36.41,;-7.57,-35.7,;-6.27,-36.55,;-6.36,-38.09,)| Show InChI InChI=1S/C26H21FN2O2/c27-19-8-5-16(6-9-19)18-7-10-22-23(15-18)29-24(28-22)17-11-13-26(14-12-17)21-4-2-1-3-20(21)25(30)31-26/h1-10,15,17H,11-14H2,(H,28,29)/t17-,26-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 18: 4997-5001 (2008) Article DOI: 10.1016/j.bmcl.2008.08.021 BindingDB Entry DOI: 10.7270/Q25H7G2P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Rat 6B)	BDBM50304297 (CHEMBL594163 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1ccn(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21 |r,wU:17.22,wD:14.15,(24.81,-8.6,;25.58,-9.94,;27.12,-9.94,;28,-11.21,;29.55,-11.24,;29.99,-12.71,;28.72,-13.59,;27.5,-12.65,;28.69,-15.12,;27.34,-15.86,;27.3,-17.4,;28.62,-18.2,;29.97,-17.45,;30,-15.91,;24.81,-11.27,;23.27,-11.27,;22.5,-12.6,;23.27,-13.93,;24.81,-13.93,;25.58,-12.6,;24.19,-15.19,;23.28,-16.44,;23.75,-17.91,;21.8,-15.96,;20.47,-16.74,;19.14,-15.96,;19.14,-14.42,;20.47,-13.65,;21.8,-14.41,)| Show InChI InChI=1S/C22H20N4O3/c27-20(24-18-10-14-26(25-18)16-5-2-1-3-6-16)15-8-11-22(12-9-15)17-7-4-13-23-19(17)21(28)29-22/h1-7,10,13-15H,8-9,11-12H2,(H,24,25,27)/t15-,22-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of rat Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50296185 (CHEMBL550393 | trans-1-(3-(4-(3-methyl-2,3-dihydro...) Show SMILES C[C@H]1Sc2ccccc2O[C@@H]1c1ccc(OCCCN2CCCC2)cc1 |r| Show InChI InChI=1S/C22H27NO2S/c1-17-22(25-20-7-2-3-8-21(20)26-17)18-9-11-19(12-10-18)24-16-6-15-23-13-4-5-14-23/h2-3,7-12,17,22H,4-6,13-16H2,1H3/t17-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...				Bioorg Med Chem Lett 19: 4232-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.101 BindingDB Entry DOI: 10.7270/Q20G3K69
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50301656 (CHEMBL567527 | trans-1'-oxo-N-(5-phenylpyrimidin-2...) Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:18.23,wD:15.16,(28.35,-35.04,;29.11,-36.37,;30.65,-36.38,;31.49,-37.67,;30.78,-39.03,;31.62,-40.33,;33.16,-40.25,;33.86,-38.87,;33.02,-37.58,;34,-41.54,;33.29,-42.91,;34.13,-44.2,;35.67,-44.13,;36.37,-42.75,;35.53,-41.46,;28.34,-37.71,;26.8,-37.71,;26.03,-39.04,;26.8,-40.37,;28.34,-40.37,;29.11,-39.04,;27.72,-41.62,;26.81,-42.88,;27.29,-44.34,;25.33,-42.4,;24,-43.17,;22.67,-42.4,;22.67,-40.86,;24,-40.09,;25.33,-40.85,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-12-17(13-26-22)15-4-2-1-3-5-15)16-6-9-23(10-7-16)19-14-24-11-8-18(19)21(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,25,26,27,28)/t16-,23-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50265297 (1'-(5-isobutyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[...) Show SMILES CC(C)Cc1ccc2nc([nH]c2c1)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C23H25N3O2/c1-15(2)13-16-7-8-19-20(14-16)25-22(24-19)26-11-9-23(10-12-26)18-6-4-3-5-17(18)21(27)28-23/h3-8,14-15H,9-13H2,1-2H3,(H,24,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cells				Bioorg Med Chem Lett 18: 5010-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.018 BindingDB Entry DOI: 10.7270/Q26D5STS
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50265267 (1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...) Show SMILES O=C1OC2(CCN(CC2)c2nc3cc(ccc3[nH]2)-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H21N3O2/c29-23-19-8-4-5-9-20(19)25(30-23)12-14-28(15-13-25)24-26-21-11-10-18(16-22(21)27-24)17-6-2-1-3-7-17/h1-11,16H,12-15H2,(H,26,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...				Bioorg Med Chem Lett 18: 5010-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.018 BindingDB Entry DOI: 10.7270/Q26D5STS
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50265299 (CHEMBL524644 | ethyl 2-(3-oxo-3H-spiro[isobenzofur...) Show SMILES CCOC(=O)c1ccc2nc([nH]c2c1)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C22H21N3O4/c1-2-28-19(26)14-7-8-17-18(13-14)24-21(23-17)25-11-9-22(10-12-25)16-6-4-3-5-15(16)20(27)29-22/h3-8,13H,2,9-12H2,1H3,(H,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cells				Bioorg Med Chem Lett 18: 5010-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.018 BindingDB Entry DOI: 10.7270/Q26D5STS
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304316 (CHEMBL594164 | trans-N-[1-(4-Fluorophenyl)-1H-pyra...) Show SMILES Fc1cccc(c1)-n1ccc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)n1 |r,wU:17.21,wD:14.14,(32.55,-32.84,;31.21,-32.08,;29.88,-32.85,;28.54,-32.08,;28.54,-30.54,;29.88,-29.78,;31.21,-30.54,;29.88,-28.24,;31.13,-27.34,;30.65,-25.87,;29.11,-25.88,;28.2,-24.63,;26.66,-24.63,;25.9,-23.29,;25.89,-25.96,;24.35,-25.96,;23.58,-27.3,;24.35,-28.62,;25.89,-28.62,;26.66,-27.3,;25.27,-29.88,;24.36,-31.14,;24.84,-32.6,;22.88,-30.66,;21.55,-31.43,;20.22,-30.66,;20.22,-29.11,;21.55,-28.34,;22.88,-29.11,;28.63,-27.34,)| Show InChI InChI=1S/C22H19FN4O3/c23-15-2-1-3-16(12-15)27-11-7-19(26-27)25-20(28)14-4-8-22(9-5-14)18-13-24-10-6-17(18)21(29)30-22/h1-3,6-7,10-14H,4-5,8-9H2,(H,25,26,28)/t14-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50301651 (CHEMBL568370 | trans-3'-oxo-N-(5-phenylpyrimidin-2...) Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cnccc21 |r,wU:18.23,wD:15.16,(26.14,-22.21,;26.91,-23.55,;28.45,-23.55,;29.28,-24.84,;28.58,-26.21,;29.41,-27.5,;30.95,-27.43,;31.65,-26.05,;30.81,-24.76,;31.79,-28.72,;31.08,-30.09,;31.92,-31.38,;33.46,-31.3,;34.16,-29.92,;33.32,-28.63,;26.13,-24.88,;24.59,-24.88,;23.82,-26.21,;24.59,-27.54,;26.13,-27.54,;26.9,-26.21,;25.51,-28.8,;24.6,-30.05,;25.08,-31.52,;23.13,-29.58,;21.79,-30.35,;20.46,-29.58,;20.46,-28.03,;21.79,-27.26,;23.12,-28.02,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-12-17(13-26-22)15-4-2-1-3-5-15)16-6-9-23(10-7-16)19-8-11-24-14-18(19)21(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,25,26,27,28)/t16-,23-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Rat 6B)	BDBM50304300 (CHEMBL595573 | trans-N-[1-(2-fluorophenyl)-3-pyraz...) Show SMILES Fc1ccccc1-n1ccc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)n1 |r,wU:17.21,wD:14.14,(16.87,-28.98,;15.54,-29.75,;15.54,-31.28,;14.2,-32.06,;12.87,-31.29,;12.87,-29.75,;14.21,-28.98,;14.21,-27.45,;15.45,-26.55,;14.98,-25.08,;13.44,-25.08,;12.53,-23.84,;10.99,-23.84,;10.22,-22.5,;10.22,-25.17,;8.68,-25.17,;7.91,-26.5,;8.68,-27.83,;10.22,-27.83,;10.99,-26.5,;9.6,-29.09,;8.69,-30.34,;9.16,-31.81,;7.21,-29.86,;5.88,-30.63,;4.55,-29.86,;4.55,-28.32,;5.88,-27.55,;7.21,-28.31,;12.96,-26.54,)| Show InChI InChI=1S/C22H19FN4O3/c23-17-3-1-2-4-18(17)27-12-8-19(26-27)25-20(28)14-5-9-22(10-6-14)16-13-24-11-7-15(16)21(29)30-22/h1-4,7-8,11-14H,5-6,9-10H2,(H,25,26,28)/t14-,22-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of rat Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50264493 (CHEMBL489608 | trans-4-[5-(5-Trifluoromethyl-[1,2,...) Show SMILES FC(F)(F)c1nc(no1)-c1ccc2[nH]c(nc2c1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21 |r,wU:21.27,wD:18.20,(7.51,-37.15,;6.75,-38.49,;5.36,-37.84,;8.14,-39.15,;6.2,-39.93,;4.72,-40.33,;4.64,-41.87,;6.08,-42.41,;7.04,-41.21,;3.36,-42.71,;3.44,-44.25,;2.15,-45.08,;.79,-44.38,;-.64,-44.94,;-1.61,-43.73,;-.77,-42.45,;.71,-42.85,;1.99,-42.02,;-3.15,-43.81,;-3.99,-42.51,;-5.53,-42.6,;-6.23,-43.97,;-5.39,-45.27,;-3.85,-45.19,;-6.94,-45.35,;-8.46,-45.1,;-9.55,-46.19,;-8.7,-43.58,;-9.99,-42.74,;-9.92,-41.2,;-8.53,-40.49,;-7.24,-41.34,;-7.32,-42.88,)| Show InChI InChI=1S/C23H17F3N4O3/c24-23(25,26)21-29-19(30-33-21)13-5-6-16-17(11-13)28-18(27-16)12-7-9-22(10-8-12)15-4-2-1-3-14(15)20(31)32-22/h1-6,11-12H,7-10H2,(H,27,28)/t12-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 18: 4997-5001 (2008) Article DOI: 10.1016/j.bmcl.2008.08.021 BindingDB Entry DOI: 10.7270/Q25H7G2P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Rat 6B)	BDBM50304301 (CHEMBL595790 | trans-N-[1-(3-Fluorophenyl)-1H-pyra...) Show SMILES Fc1ccc(cc1)-n1ccc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)n1 |r,wU:17.21,wD:14.14,(.68,-45.87,;.68,-44.33,;-.66,-43.55,;-.65,-42.02,;.68,-41.25,;2.01,-42.01,;2.02,-43.55,;.68,-39.72,;1.93,-38.81,;1.45,-37.35,;-.09,-37.35,;-.99,-36.1,;-2.53,-36.1,;-3.3,-34.77,;-3.31,-37.43,;-4.85,-37.43,;-5.62,-38.77,;-4.85,-40.09,;-3.31,-40.09,;-2.54,-38.77,;-3.93,-41.35,;-4.84,-42.61,;-4.36,-44.07,;-6.31,-42.13,;-7.65,-42.9,;-8.98,-42.13,;-8.98,-40.58,;-7.65,-39.81,;-6.31,-40.58,;-.56,-38.81,)| Show InChI InChI=1S/C22H19FN4O3/c23-15-1-3-16(4-2-15)27-12-8-19(26-27)25-20(28)14-5-9-22(10-6-14)18-13-24-11-7-17(18)21(29)30-22/h1-4,7-8,11-14H,5-6,9-10H2,(H,25,26,28)/t14-,22-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of rat Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304312 (CHEMBL604480 | trans-3-Oxo-N-(5-phenylpyridin-2-yl...) Show SMILES O=C(Nc1ccc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:18.23,wD:15.16,(24.78,5.17,;25.55,3.84,;27.09,3.84,;27.93,2.54,;27.22,1.18,;28.05,-.12,;29.59,-.04,;30.29,1.34,;29.45,2.63,;30.43,-1.33,;29.72,-2.7,;30.56,-3.99,;32.1,-3.92,;32.8,-2.53,;31.96,-1.25,;24.78,2.51,;23.24,2.51,;22.47,1.17,;23.24,-.16,;24.78,-.16,;25.55,1.17,;24.16,-1.41,;23.25,-2.67,;23.72,-4.13,;21.77,-2.19,;20.44,-2.96,;19.11,-2.19,;19.11,-.65,;20.44,.13,;21.77,-.64,)| Show InChI InChI=1S/C24H21N3O3/c28-22(27-21-7-6-18(14-26-21)16-4-2-1-3-5-16)17-8-11-24(12-9-17)20-15-25-13-10-19(20)23(29)30-24/h1-7,10,13-15,17H,8-9,11-12H2,(H,26,27,28)/t17-,24-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304310 (CHEMBL596264 | trans-3-Oxo-N-(5-phenylisoxazol-3-y...) Show SMILES O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(-3.73,5.98,;-2.96,4.65,;-1.42,4.65,;-.52,3.4,;-1,1.93,;.24,1.03,;1.49,1.93,;1.01,3.39,;.24,-.51,;-1.1,-1.28,;-1.1,-2.82,;.23,-3.59,;1.57,-2.81,;1.57,-1.28,;-3.73,3.31,;-5.27,3.31,;-6.05,1.98,;-5.27,.65,;-3.73,.65,;-2.97,1.98,;-4.35,-.6,;-5.27,-1.86,;-4.79,-3.32,;-6.74,-1.38,;-8.07,-2.15,;-9.41,-1.38,;-9.41,.16,;-8.08,.93,;-6.74,.17,)| Show InChI InChI=1S/C22H19N3O4/c26-20(24-19-12-18(29-25-19)14-4-2-1-3-5-14)15-6-9-22(10-7-15)17-13-23-11-8-16(17)21(27)28-22/h1-5,8,11-13,15H,6-7,9-10H2,(H,24,25,26)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50301644 (CHEMBL568144 | trans-3-Oxo-N-(5-phenylpyrimidin-2-...) Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21 |r,wU:18.23,wD:15.16,(27.63,5.75,;28.4,4.41,;29.94,4.41,;30.71,3.08,;29.93,1.75,;30.7,.41,;32.24,.41,;33.01,1.75,;32.24,3.08,;33.01,-.92,;32.24,-2.25,;33,-3.58,;34.55,-3.58,;35.32,-2.24,;34.54,-.91,;27.63,3.08,;26.09,3.08,;25.31,1.75,;26.09,.42,;27.63,.42,;28.39,1.75,;27.01,-.84,;26.09,-2.09,;26.57,-3.56,;24.62,-1.61,;23.29,-2.39,;21.95,-1.61,;21.95,-.07,;23.28,.7,;24.62,-.06,)| Show InChI InChI=1S/C23H20N4O3/c28-20(27-22-25-13-17(14-26-22)15-5-2-1-3-6-15)16-8-10-23(11-9-16)18-7-4-12-24-19(18)21(29)30-23/h1-7,12-14,16H,8-11H2,(H,25,26,27,28)/t16-,23-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50264395 (CHEMBL490824 | trans-4-(5-Chloro-6-phenyl-1H-benzo...) Show SMILES Clc1cc2[nH]c(nc2cc1-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21 |r,wU:19.25,wD:16.18,(4.88,-25.91,;3.6,-26.75,;2.23,-26.06,;.95,-26.89,;-.53,-26.49,;-1.37,-27.78,;-.4,-28.98,;1.03,-28.43,;2.39,-29.12,;3.68,-28.29,;5.05,-28.98,;5.12,-30.52,;6.49,-31.22,;7.79,-30.38,;7.7,-28.84,;6.33,-28.15,;-2.91,-27.86,;-3.75,-26.55,;-5.29,-26.64,;-6,-28.01,;-5.15,-29.31,;-3.61,-29.23,;-6.7,-29.39,;-8.23,-29.15,;-9.31,-30.24,;-8.47,-27.62,;-9.76,-26.78,;-9.68,-25.24,;-8.29,-24.53,;-7,-25.38,;-7.08,-26.92,)| Show InChI InChI=1S/C26H21ClN2O2/c27-21-15-23-22(14-19(21)16-6-2-1-3-7-16)28-24(29-23)17-10-12-26(13-11-17)20-9-5-4-8-18(20)25(30)31-26/h1-9,14-15,17H,10-13H2,(H,28,29)/t17-,26-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 18: 4997-5001 (2008) Article DOI: 10.1016/j.bmcl.2008.08.021 BindingDB Entry DOI: 10.7270/Q25H7G2P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304309 (CHEMBL607144 | trans-3-Oxo-N-(5-phenylpyrazin-2-yl...) Show SMILES O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:18.23,wD:15.16,(12.25,-35.6,;13.01,-36.93,;14.55,-36.94,;15.39,-38.23,;14.68,-39.59,;15.52,-40.89,;17.06,-40.81,;17.76,-39.43,;16.92,-38.14,;17.9,-42.1,;17.19,-43.47,;18.03,-44.76,;19.57,-44.69,;20.27,-43.31,;19.43,-42.02,;12.24,-38.27,;10.7,-38.27,;9.93,-39.6,;10.7,-40.93,;12.24,-40.93,;13.01,-39.6,;11.62,-42.18,;10.71,-43.44,;11.19,-44.9,;9.23,-42.96,;7.9,-43.73,;6.57,-42.96,;6.57,-41.42,;7.9,-40.65,;9.23,-41.41,)| Show InChI InChI=1S/C23H20N4O3/c28-21(27-20-14-25-19(13-26-20)15-4-2-1-3-5-15)16-6-9-23(10-7-16)18-12-24-11-8-17(18)22(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,26,27,28)/t16-,23-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304314 (CHEMBL596025 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1cnn(c1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(25.62,-7.99,;26.39,-9.32,;27.93,-9.32,;28.84,-10.57,;30.38,-10.57,;30.85,-12.03,;29.61,-12.94,;28.36,-12.03,;29.61,-14.47,;28.27,-15.24,;28.27,-16.77,;29.6,-17.55,;30.94,-16.77,;30.94,-15.23,;25.62,-10.65,;24.08,-10.65,;23.31,-11.99,;24.08,-13.32,;25.62,-13.32,;26.39,-11.99,;25,-14.57,;24.09,-15.83,;24.56,-17.29,;22.61,-15.35,;21.28,-16.12,;19.95,-15.35,;19.95,-13.81,;21.28,-13.03,;22.61,-13.8,)| Show InChI InChI=1S/C22H20N4O3/c27-20(25-16-12-24-26(14-16)17-4-2-1-3-5-17)15-6-9-22(10-7-15)19-13-23-11-8-18(19)21(28)29-22/h1-5,8,11-15H,6-7,9-10H2,(H,25,27)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Rat 6B)	BDBM50304299 (CHEMBL595560 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1ccn(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(12.31,-8.24,;13.08,-9.57,;14.62,-9.57,;15.45,-10.87,;16.99,-10.95,;17.38,-12.44,;16.09,-13.28,;14.9,-12.31,;16.01,-14.82,;14.63,-15.51,;14.55,-17.04,;15.84,-17.89,;17.22,-17.18,;17.3,-15.65,;12.3,-10.9,;10.76,-10.9,;9.99,-12.24,;10.76,-13.56,;12.3,-13.56,;13.07,-12.24,;11.68,-14.82,;10.77,-16.08,;11.25,-17.54,;9.3,-15.6,;7.96,-16.37,;6.63,-15.6,;6.63,-14.05,;7.96,-13.28,;9.3,-14.05,)| Show InChI InChI=1S/C22H20N4O3/c27-20(24-19-9-13-26(25-19)16-4-2-1-3-5-16)15-6-10-22(11-7-15)18-14-23-12-8-17(18)21(28)29-22/h1-5,8-9,12-15H,6-7,10-11H2,(H,24,25,27)/t15-,22-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of rat Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50264441 (CHEMBL491239 | trans-6-Chloro-2-(3'-oxo-3'H-spiro[...) Show SMILES COC(=O)c1cc2[nH]c(nc2cc1Cl)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21 |r,wU:17.22,wD:14.15,(31.64,-2.03,;30.27,-1.33,;28.98,-2.17,;29.06,-3.7,;27.61,-1.47,;26.33,-2.3,;24.97,-1.6,;23.53,-2.16,;22.57,-.95,;23.41,.33,;24.89,-.07,;26.17,.76,;27.53,.07,;28.82,.91,;21.03,-1.03,;20.19,.27,;18.65,.18,;17.95,-1.19,;18.79,-2.49,;20.33,-2.41,;17.24,-2.57,;15.72,-2.33,;14.63,-3.41,;15.47,-.8,;14.18,.04,;14.26,1.58,;15.65,2.29,;16.94,1.44,;16.86,-.1,)| Show InChI InChI=1S/C22H19ClN2O4/c1-28-20(26)14-10-17-18(11-16(14)23)25-19(24-17)12-6-8-22(9-7-12)15-5-3-2-4-13(15)21(27)29-22/h2-5,10-12H,6-9H2,1H3,(H,24,25)/t12-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 18: 4997-5001 (2008) Article DOI: 10.1016/j.bmcl.2008.08.021 BindingDB Entry DOI: 10.7270/Q25H7G2P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50264853 (1'-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazo...) Show SMILES FC1(F)Oc2cc3nc([nH]c3cc2O1)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C20H15F2N3O4/c21-20(22)27-15-9-13-14(10-16(15)28-20)24-18(23-13)25-7-5-19(6-8-25)12-4-2-1-3-11(12)17(26)29-19/h1-4,9-10H,5-8H2,(H,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cells				Bioorg Med Chem Lett 18: 5010-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.018 BindingDB Entry DOI: 10.7270/Q26D5STS
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50264328 (CHEMBL489587 | trans-4-(5-Phenyl-1H-benzoimidazol-...) Show SMILES O=C1O[C@]2(CC[C@@H](CC2)c2nc3ccc(cc3[nH]2)-c2ccccc2)c2ccccc12 |r,wU:3.2,wD:6.9,(15.66,-28.28,;16.75,-27.19,;18.28,-27.44,;18.98,-26.06,;19.69,-24.69,;21.23,-24.6,;22.07,-25.9,;21.37,-27.28,;19.82,-27.36,;23.6,-25.82,;24.57,-27.02,;26.01,-26.47,;27.37,-27.17,;28.66,-26.34,;28.57,-24.8,;27.21,-24.11,;25.93,-24.94,;24.45,-24.54,;29.86,-23.96,;31.23,-24.66,;32.52,-23.82,;32.43,-22.28,;31.05,-21.59,;29.77,-22.43,;17.89,-24.97,;17.98,-23.43,;16.68,-22.58,;15.3,-23.28,;15.22,-24.82,;16.51,-25.67,)| Show InChI InChI=1S/C26H22N2O2/c29-25-20-8-4-5-9-21(20)26(30-25)14-12-18(13-15-26)24-27-22-11-10-19(16-23(22)28-24)17-6-2-1-3-7-17/h1-11,16,18H,12-15H2,(H,27,28)/t18-,26-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 18: 4997-5001 (2008) Article DOI: 10.1016/j.bmcl.2008.08.021 BindingDB Entry DOI: 10.7270/Q25H7G2P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304299 (CHEMBL595560 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1ccn(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(12.31,-8.24,;13.08,-9.57,;14.62,-9.57,;15.45,-10.87,;16.99,-10.95,;17.38,-12.44,;16.09,-13.28,;14.9,-12.31,;16.01,-14.82,;14.63,-15.51,;14.55,-17.04,;15.84,-17.89,;17.22,-17.18,;17.3,-15.65,;12.3,-10.9,;10.76,-10.9,;9.99,-12.24,;10.76,-13.56,;12.3,-13.56,;13.07,-12.24,;11.68,-14.82,;10.77,-16.08,;11.25,-17.54,;9.3,-15.6,;7.96,-16.37,;6.63,-15.6,;6.63,-14.05,;7.96,-13.28,;9.3,-14.05,)| Show InChI InChI=1S/C22H20N4O3/c27-20(24-19-9-13-26(25-19)16-4-2-1-3-5-16)15-6-10-22(11-7-15)18-14-23-12-8-17(18)21(28)29-22/h1-5,8-9,12-15H,6-7,10-11H2,(H,24,25,27)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair

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