Compile Data Set for Download or QSAR

Found 92 hits with Last Name = 'bohmer' and Initial = 'fd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6595 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(dimethy...) Show SMILES CN(C)CC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C21H19N3O3/c1-24(2)12-20(25)27-15-7-8-17-14(9-15)11-19(23-17)21(26)18-10-13-5-3-4-6-16(13)22-18/h3-11,22-23H,12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6581 ((5-Hydroxy-1H-2-indolyl)(1H-2-indolyl)-methanone |...) Show SMILES Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C17H12N2O2/c20-12-5-6-14-11(7-12)9-16(19-14)17(21)15-8-10-3-1-2-4-13(10)18-15/h1-9,18-20H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6609 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-methoxya...) Show SMILES COCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C20H16N2O4/c1-25-11-19(23)26-14-6-7-16-13(8-14)10-18(22-16)20(24)17-9-12-4-2-3-5-15(12)21-17/h2-10,21-22H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6592 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl acetate | ...) Show SMILES CC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C19H14N2O3/c1-11(22)24-14-6-7-16-13(8-14)10-18(21-16)19(23)17-9-12-4-2-3-5-15(12)20-17/h2-10,20-21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6574 ((6-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...) Show SMILES COc1ccc2cc([nH]c2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C18H14N2O2/c1-22-13-7-6-12-9-17(20-15(12)10-13)18(21)16-8-11-4-2-3-5-14(11)19-16/h2-10,19-20H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6573 ((5-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...) Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C18H14N2O2/c1-22-13-6-7-15-12(8-13)10-17(20-15)18(21)16-9-11-4-2-3-5-14(11)19-16/h2-10,19-20H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6610 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl quinoline-...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1ccc2ccccc2n1 Show InChI InChI=1S/C27H17N3O3/c31-26(24-14-17-6-2-4-8-21(17)29-24)25-15-18-13-19(10-12-22(18)30-25)33-27(32)23-11-9-16-5-1-3-7-20(16)28-23/h1-15,29-30H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6608 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl furan-2-ca...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1ccco1 Show InChI InChI=1S/C22H14N2O4/c25-21(18-11-13-4-1-2-5-16(13)23-18)19-12-14-10-15(7-8-17(14)24-19)28-22(26)20-6-3-9-27-20/h1-12,23-24H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6587 ((2-{[2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl]oxy}e...) Show SMILES CN(C)CCOc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C21H21N3O2/c1-24(2)9-10-26-16-7-8-18-15(11-16)13-20(23-18)21(25)19-12-14-5-3-4-6-17(14)22-19/h3-8,11-13,22-23H,9-10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6591 (1H-2-Indolyl-[5-(2-piperidin-1-ylethoxy)-1H-2-indo...) Show SMILES O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCCN3CCCCC3)ccc2[nH]1 Show InChI InChI=1S/C24H25N3O2/c28-24(22-15-17-6-2-3-7-20(17)25-22)23-16-18-14-19(8-9-21(18)26-23)29-13-12-27-10-4-1-5-11-27/h2-3,6-9,14-16,25-26H,1,4-5,10-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6602 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl benzoate |...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1ccccc1 Show InChI InChI=1S/C24H16N2O3/c27-23(21-13-16-8-4-5-9-19(16)25-21)22-14-17-12-18(10-11-20(17)26-22)29-24(28)15-6-2-1-3-7-15/h1-14,25-26H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6597 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(thiophe...) Show SMILES O=C(Cc1cccs1)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C23H16N2O3S/c26-22(13-17-5-3-9-29-17)28-16-7-8-19-15(10-16)12-21(25-19)23(27)20-11-14-4-1-2-6-18(14)24-20/h1-12,24-25H,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6596 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl propanoate...) Show SMILES CCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C20H16N2O3/c1-2-19(23)25-14-7-8-16-13(9-14)11-18(22-16)20(24)17-10-12-5-3-4-6-15(12)21-17/h3-11,21-22H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6605 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 4-nitroben...) Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C24H15N3O5/c28-23(21-12-15-3-1-2-4-19(15)25-21)22-13-16-11-18(9-10-20(16)26-22)32-24(29)14-5-7-17(8-6-14)27(30)31/h1-13,25-26H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6601 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(acetylo...) Show SMILES [H]C(OC(C)=O)(C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1ccccc1 |w:1.0| Show InChI InChI=1S/C27H20N2O5/c1-16(30)33-26(17-7-3-2-4-8-17)27(32)34-20-11-12-22-19(13-20)15-24(29-22)25(31)23-14-18-9-5-6-10-21(18)28-23/h2-15,26,28-29H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6578 ((Benzo[b]thiophen-2-yl)(5-methoxy-1H-2-indolyl)-1-...) Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2s1 Show InChI InChI=1S/C18H13NO2S/c1-21-13-6-7-14-12(8-13)9-15(19-14)18(20)17-10-11-4-2-3-5-16(11)22-17/h2-10,19H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5171 ((2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol...) Show SMILES Oc1ccc(cc1O)C(=O)C(=C\c1c[nH]c2ccccc12)\C#N Show InChI InChI=1S/C18H12N2O3/c19-9-12(18(23)11-5-6-16(21)17(22)8-11)7-13-10-20-15-4-2-1-3-14(13)15/h1-8,10,20-22H/b12-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6603 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(3-metho...) Show SMILES COc1cccc(CC(=O)Oc2ccc3[nH]c(cc3c2)C(=O)c2cc3ccccc3[nH]2)c1 Show InChI InChI=1S/C26H20N2O4/c1-31-19-7-4-5-16(11-19)12-25(29)32-20-9-10-22-18(13-20)15-24(28-22)26(30)23-14-17-6-2-3-8-21(17)27-23/h2-11,13-15,27-28H,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6614 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl pyridine-3...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1cccnc1 Show InChI InChI=1S/C23H15N3O3/c27-22(20-11-14-4-1-2-6-18(14)25-20)21-12-16-10-17(7-8-19(16)26-21)29-23(28)15-5-3-9-24-13-15/h1-13,25-26H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6594 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl butanoate ...) Show SMILES CCCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C21H18N2O3/c1-2-5-20(24)26-15-8-9-17-14(10-15)12-19(23-17)21(25)18-11-13-6-3-4-7-16(13)22-18/h3-4,6-12,22-23H,2,5H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6600 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 3-phenylpr...) Show SMILES O=C(CCc1ccccc1)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C26H20N2O3/c29-25(13-10-17-6-2-1-3-7-17)31-20-11-12-22-19(14-20)16-24(28-22)26(30)23-15-18-8-4-5-9-21(18)27-23/h1-9,11-12,14-16,27-28H,10,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6611 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 4-ethoxybe...) Show SMILES CCOc1ccc(cc1)C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C26H20N2O4/c1-2-31-19-9-7-16(8-10-19)26(30)32-20-11-12-22-18(13-20)15-24(28-22)25(29)23-14-17-5-3-4-6-21(17)27-23/h3-15,27-28H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5183 (2-Chloro-3-phenyl-6,7-dimethoxyquinoline | 2-chlor...) Show SMILES COc1cc2cc(c(Cl)nc2cc1OC)-c1ccccc1 Show InChI InChI=1S/C17H14ClNO2/c1-20-15-9-12-8-13(11-6-4-3-5-7-11)17(18)19-14(12)10-16(15)21-2/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6599 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 4-phenylbe...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C30H20N2O3/c33-29(27-17-22-8-4-5-9-25(22)31-27)28-18-23-16-24(14-15-26(23)32-28)35-30(34)21-12-10-20(11-13-21)19-6-2-1-3-7-19/h1-18,31-32H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6598 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(acetylo...) Show SMILES CC(=O)Oc1ccccc1C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C26H18N2O5/c1-15(29)32-24-9-5-3-7-19(24)26(31)33-18-10-11-21-17(12-18)14-23(28-21)25(30)22-13-16-6-2-4-8-20(16)27-22/h2-14,27-28H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6583 ((5-Ethoxy-1H-2-indolyl)(1H-2-indolyl)methanone | 5...) Show SMILES CCOc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C19H16N2O2/c1-2-23-14-7-8-16-13(9-14)11-18(21-16)19(22)17-10-12-5-3-4-6-15(12)20-17/h3-11,20-21H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6584 (1H-2-Indolyl-[5-(2-(morpholin-1-yl)ethoxy)-1H-2-in...) Show SMILES O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCCN3CCOCC3)ccc2[nH]1 Show InChI InChI=1S/C23H23N3O3/c27-23(21-14-16-3-1-2-4-19(16)24-21)22-15-17-13-18(5-6-20(17)25-22)29-12-9-26-7-10-28-11-8-26/h1-6,13-15,24-25H,7-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6585 ((3-{[2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl]oxy}p...) Show SMILES CN(C)CCCOc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C22H23N3O2/c1-25(2)10-5-11-27-17-8-9-19-16(12-17)14-21(24-19)22(26)20-13-15-6-3-4-7-18(15)23-20/h3-4,6-9,12-14,23-24H,5,10-11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6593 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 4-methoxyb...) Show SMILES COc1ccc(cc1)C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C25H18N2O4/c1-30-18-8-6-15(7-9-18)25(29)31-19-10-11-21-17(12-19)14-23(27-21)24(28)22-13-16-4-2-3-5-20(16)26-22/h2-14,26-27H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6607 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl (2E)-3-phe...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)\C=C\c1ccccc1 Show InChI InChI=1S/C26H18N2O3/c29-25(13-10-17-6-2-1-3-7-17)31-20-11-12-22-19(14-20)16-24(28-22)26(30)23-15-18-8-4-5-9-21(18)27-23/h1-16,27-28H/b13-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6579 ((Benzo[b]furan-2-yl)(5-methoxy-1H-2-indolyl)methan...) Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2o1 Show InChI InChI=1S/C18H13NO3/c1-21-13-6-7-14-12(8-13)9-15(19-14)18(20)17-10-11-4-2-3-5-16(11)22-17/h2-10,19H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6606 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 3,4,5-trim...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C27H22N2O6/c1-32-23-13-17(14-24(33-2)26(23)34-3)27(31)35-18-8-9-20-16(10-18)12-22(29-20)25(30)21-11-15-6-4-5-7-19(15)28-21/h4-14,28-29H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6604 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-chlorobe...) Show SMILES Clc1ccccc1C(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C24H15ClN2O3/c25-18-7-3-2-6-17(18)24(29)30-16-9-10-20-15(11-16)13-22(27-20)23(28)21-12-14-5-1-4-8-19(14)26-21/h1-13,26-27H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6613 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl cyclobutan...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)C1CCC1 Show InChI InChI=1S/C22H18N2O3/c25-21(19-11-14-4-1-2-7-17(14)23-19)20-12-15-10-16(8-9-18(15)24-20)27-22(26)13-5-3-6-13/h1-2,4,7-13,23-24H,3,5-6H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5176 ((2E)-2-cyano-3-(1H-indol-3-yl)prop-2-enamide | Ind...) Show SMILES NC(=O)C(=C\c1c[nH]c2ccccc12)\C#N Show InChI InChI=1S/C12H9N3O/c13-6-8(12(14)16)5-9-7-15-11-4-2-1-3-10(9)11/h1-5,7,15H,(H2,14,16)/b8-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5173 ((2E)-2-cyano-3-(1H-indol-3-yl)prop-2-enethioamide ...) Show SMILES NC(=S)C(=C\c1c[nH]c2ccccc12)\C#N Show InChI InChI=1S/C12H9N3S/c13-6-8(12(14)16)5-9-7-15-11-4-2-1-3-10(9)11/h1-5,7,15H,(H2,14,16)/b8-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6577 ((1H-2-Indolyl)(5-methyl-1H-2-indolyl)methanone | 2...) Show SMILES Cc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C18H14N2O/c1-11-6-7-15-13(8-11)10-17(20-15)18(21)16-9-12-4-2-3-5-14(12)19-16/h2-10,19-20H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6612 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl cyclopropa...) Show SMILES O=C(Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1)C1CC1 Show InChI InChI=1S/C21H16N2O3/c24-20(18-10-13-3-1-2-4-16(13)22-18)19-11-14-9-15(7-8-17(14)23-19)26-21(25)12-5-6-12/h1-4,7-12,22-23H,5-6H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4304 ((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)Nc2ccccc2)cc1O Show InChI InChI=1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	4
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5187 (2-(quinolin-4-ylmethylidene)propanedinitrile | 4-Q...) Show SMILES N#C\[#6](=[#6]\c1ccnc2ccccc12)C#N Show InChI InChI=1S/C13H7N3/c14-8-10(9-15)7-11-5-6-16-13-4-2-1-3-12(11)13/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4304 ((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...) Show SMILES Oc1ccc(\C=C(/C#N)C(=O)Nc2ccccc2)cc1O Show InChI InChI=1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5170 ((2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol...) Show SMILES Oc1ccc(cc1O)C(=O)C(=C\c1ccc2[nH]ccc2c1)\C#N Show InChI InChI=1S/C18H12N2O3/c19-10-14(18(23)13-2-4-16(21)17(22)9-13)8-11-1-3-15-12(7-11)5-6-20-15/h1-9,20-22H/b14-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	4
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5170 ((2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol...) Show SMILES Oc1ccc(cc1O)C(=O)C(=C\c1ccc2[nH]ccc2c1)\C#N Show InChI InChI=1S/C18H12N2O3/c19-10-14(18(23)13-2-4-16(21)17(22)9-13)8-11-1-3-15-12(7-11)5-6-20-15/h1-9,20-22H/b14-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5187 (2-(quinolin-4-ylmethylidene)propanedinitrile | 4-Q...) Show SMILES N#C\[#6](=[#6]\c1ccnc2ccccc12)C#N Show InChI InChI=1S/C13H7N3/c14-8-10(9-15)7-11-5-6-16-13-4-2-1-3-12(11)13/h1-7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	4
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5169 ((2E)-2-cyano-3-(1H-indol-5-yl)-N-(1-phenylethyl)pr...) Show SMILES CC(NC(=O)C(=C\c1ccc2[nH]ccc2c1)\C#N)c1ccccc1 Show InChI InChI=1S/C20H17N3O/c1-14(16-5-3-2-4-6-16)23-20(24)18(13-21)12-15-7-8-19-17(11-15)9-10-22-19/h2-12,14,22H,1H3,(H,23,24)/b18-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	4
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6586 (2-(1H-indol-2-ylcarbonyl)-5-(4-iodobutoxy)-1H-indo...) Show SMILES ICCCCOc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C21H19IN2O2/c22-9-3-4-10-26-16-7-8-18-15(11-16)13-20(24-18)21(25)19-12-14-5-1-2-6-17(14)23-19/h1-2,5-8,11-13,23-24H,3-4,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5175 ((2E)-2-benzoyl-3-(1H-indol-3-yl)prop-2-enenitrile ...) Show SMILES O=C(\C(=C\c1c[nH]c2ccccc12)C#N)c1ccccc1 Show InChI InChI=1S/C18H12N2O/c19-11-14(18(21)13-6-2-1-3-7-13)10-15-12-20-17-9-5-4-8-16(15)17/h1-10,12,20H/b14-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM5174 ((3Z)-2-amino-3-(1H-indol-3-ylmethylidene)prop-1-en...) Show SMILES N=C(C(C#N)C#N)C(=Cc1c[nH]c2ccccc12)C#N |w:8.8| Show InChI InChI=1S/C15H9N5/c16-6-10(15(19)12(7-17)8-18)5-11-9-20-14-4-2-1-3-13(11)14/h1-5,9,12,19-20H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hebrew University of Jerusalem					Assay Description The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...				J Med Chem 39: 2170-7 (1996) Article DOI: 10.1021/jm950727b BindingDB Entry DOI: 10.7270/Q2QF8R2N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6576 (5-methoxy-2-[(5-methoxy-1H-indol-2-yl)carbonyl]-1H...) Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc2cc(OC)ccc2[nH]1 Show InChI InChI=1S/C19H16N2O3/c1-23-13-3-5-15-11(7-13)9-17(20-15)19(22)18-10-12-8-14(24-2)4-6-16(12)21-18/h3-10,20-21H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6582 (5-(benzyloxy)-2-(1H-indol-2-ylcarbonyl)-1H-indole ...) Show SMILES O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCc3ccccc3)ccc2[nH]1 Show InChI InChI=1S/C24H18N2O2/c27-24(22-13-17-8-4-5-9-20(17)25-22)23-14-18-12-19(10-11-21(18)26-23)28-15-16-6-2-1-3-7-16/h1-14,25-26H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	7.4	22
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair

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