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Compile Data Set for Download or QSAR

Found 111 hits with Last Name = 'elder' and Initial = 'js'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methionine--tRNA ligase, cytoplasmic


(Homo sapiens (Human))		BDBM50112575
PNG
(2-[3-(6,8-Dibromo-1,2,3,4-tetrahydro-quinolin-4-yl...)
Show SMILES Oc1cc(NCCCNC2CCNc3c(Br)cc(Br)cc23)nc2ccccc12
Show InChI InChI=1S/C21H22Br2N4O/c22-13-10-15-17(6-9-26-21(15)16(23)11-13)24-7-3-8-25-20-12-19(28)14-4-1-2-5-18(14)27-20/h1-2,4-5,10-12,17,24,26H,3,6-9H2,(H2,25,27,28)
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TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Methionyl-tRNA synthetase in a pyrophosphate exchange assay

J Med Chem 45: 1959-62 (2002)


BindingDB Entry DOI: 10.7270/Q2HQ3Z6X
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50222699
PNG
(CHEMBL161300)
Show SMILES Oc1cc(NCCCNC2CCNc3c(Br)cc(Cl)cc23)nc2ccccc12
Show InChI InChI=1S/C21H22BrClN4O/c22-16-11-13(23)10-15-17(6-9-26-21(15)16)24-7-3-8-25-20-12-19(28)14-4-1-2-5-18(14)27-20/h1-2,4-5,10-12,17,24,26H,3,6-9H2,(H2,25,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50222705
PNG
(CHEMBL161312)
Show SMILES CCOc1c(I)cc(I)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C21H23I2N3O2/c1-2-28-21-14(10-15(22)11-17(21)23)13-24-8-5-9-25-20-12-19(27)16-6-3-4-7-18(16)26-20/h3-4,6-7,10-12,24H,2,5,8-9,13H2,1H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50222700
PNG
(CHEMBL161864)
Show SMILES Oc1cc(NCCCNCc2cc(Br)cc(Br)c2)nc2ccccc12
Show InChI InChI=1S/C19H19Br2N3O/c20-14-8-13(9-15(21)10-14)12-22-6-3-7-23-19-11-18(25)16-4-1-2-5-17(16)24-19/h1-2,4-5,8-11,22H,3,6-7,12H2,(H2,23,24,25)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50222702
PNG
(CHEMBL161347)
Show SMILES Oc1cc(NCCCNC2CCNc3c(Cl)cc(Br)cc23)nc2ccccc12
Show InChI InChI=1S/C21H22BrClN4O/c22-13-10-15-17(6-9-26-21(15)16(23)11-13)24-7-3-8-25-20-12-19(28)14-4-1-2-5-18(14)27-20/h1-2,4-5,10-12,17,24,26H,3,6-9H2,(H2,25,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50222701
PNG
(CHEMBL158051)
Show SMILES Clc1cc(Cl)c2OCCC(NCCCNc3cc(=O)c4ccccc4[nH]3)c2c1
Show InChI InChI=1S/C21H21Cl2N3O2/c22-13-10-15-17(6-9-28-21(15)16(23)11-13)24-7-3-8-25-20-12-19(27)14-4-1-2-5-18(14)26-20/h1-2,4-5,10-12,17,24H,3,6-9H2,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124821
PNG
(2-[3-(3,5-Dichloro-benzylamino)-propylamino]-1H-qu...)
Show SMILES Oc1cc(NCCCNCc2cc(Cl)cc(Cl)c2)nc2ccccc12
Show InChI InChI=1S/C19H19Cl2N3O/c20-14-8-13(9-15(21)10-14)12-22-6-3-7-23-19-11-18(25)16-4-1-2-5-17(16)24-19/h1-2,4-5,8-11,22H,3,6-7,12H2,(H2,23,24,25)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50222703
PNG
(CHEMBL160841)
Show SMILES Oc1cc(NCCCNCc2cc(Cl)cc(Cl)c2Cl)nc2ccccc12
Show InChI InChI=1S/C19H18Cl3N3O/c20-13-8-12(19(22)15(21)9-13)11-23-6-3-7-24-18-10-17(26)14-4-1-2-5-16(14)25-18/h1-2,4-5,8-10,23H,3,6-7,11H2,(H2,24,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50222704
PNG
(CHEMBL345835)
Show SMILES CCOc1c(CNCCCNc2cc(O)c3ccccc3n2)cc(I)cc1CC=C
Show InChI InChI=1S/C24H28IN3O2/c1-3-8-17-13-19(25)14-18(24(17)30-4-2)16-26-11-7-12-27-23-15-22(29)20-9-5-6-10-21(20)28-23/h3,5-6,9-10,13-15,26H,1,4,7-8,11-12,16H2,2H3,(H2,27,28,29)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124843
PNG
(2-[3-(3-Bromo-2-ethoxy-5-methoxy-benzylamino)-prop...)
Show SMILES CCOc1c(Br)cc(OC)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26BrN3O3/c1-3-29-22-15(11-16(28-2)12-18(22)23)14-24-9-6-10-25-21-13-20(27)17-7-4-5-8-19(17)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124811
PNG
(2-[3-(3-Bromo-5-iodo-benzylamino)-propylamino]-1H-...)
Show SMILES Oc1cc(NCCCNCc2cc(Br)cc(I)c2)nc2ccccc12
Show InChI InChI=1S/C19H19BrIN3O/c20-14-8-13(9-15(21)10-14)12-22-6-3-7-23-19-11-18(25)16-4-1-2-5-17(16)24-19/h1-2,4-5,8-11,22H,3,6-7,12H2,(H2,23,24,25)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124826
PNG
(2-[3-(2-Ethoxy-5-iodo-3-methyl-benzylamino)-propyl...)
Show SMILES CCOc1c(C)cc(I)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26IN3O2/c1-3-28-22-15(2)11-17(23)12-16(22)14-24-9-6-10-25-21-13-20(27)18-7-4-5-8-19(18)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124808
PNG
(2-[3-(2-Ethoxy-3-iodo-5-methoxy-benzylamino)-propy...)
Show SMILES CCOc1c(I)cc(OC)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26IN3O3/c1-3-29-22-15(11-16(28-2)12-18(22)23)14-24-9-6-10-25-21-13-20(27)17-7-4-5-8-19(17)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149651
PNG
(2-[3-(3-Bromo-2-ethoxy-5-methoxy-benzylamino)-prop...)
Show SMILES CCOc1c(Br)cc(OC)cc1CNCCCNc1nc2ccsc2c(=O)[nH]1
Show InChI InChI=1S/C19H23BrN4O3S/c1-3-27-16-12(9-13(26-2)10-14(16)20)11-21-6-4-7-22-19-23-15-5-8-28-17(15)18(25)24-19/h5,8-10,21H,3-4,6-7,11H2,1-2H3,(H2,22,23,24,25)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124846
PNG
(2-[3-(5,7-Dichloro-1,2,3,4-tetrahydro-naphthalen-1...)
Show SMILES Oc1cc(NCCCNC2CCCc3c(Cl)cc(Cl)cc23)nc2ccccc12
Show InChI InChI=1S/C22H23Cl2N3O/c23-14-11-17-15(18(24)12-14)6-3-8-19(17)25-9-4-10-26-22-13-21(28)16-5-1-2-7-20(16)27-22/h1-2,5,7,11-13,19,25H,3-4,6,8-10H2,(H2,26,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149623
PNG
(CHEMBL424799 | N-(1H-Benzoimidazol-2-yl)-N''-(3-br...)
Show SMILES CCOc1c(Br)cc(Cl)cc1CNCCCNc1nc2ccccc2[nH]1
Show InChI InChI=1S/C19H22BrClN4O/c1-2-26-18-13(10-14(21)11-15(18)20)12-22-8-5-9-23-19-24-16-6-3-4-7-17(16)25-19/h3-4,6-7,10-11,22H,2,5,8-9,12H2,1H3,(H2,23,24,25)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124851
PNG
(4-Ethoxy-3-methyl-5-{[3-(4-oxo-1,4-dihydro-quinoli...)
Show SMILES CCOc1c(C)cc(cc1CNCCCNc1cc(O)c2ccccc2n1)C#N
Show InChI InChI=1S/C23H26N4O2/c1-3-29-23-16(2)11-17(14-24)12-18(23)15-25-9-6-10-26-22-13-21(28)19-7-4-5-8-20(19)27-22/h4-5,7-8,11-13,25H,3,6,9-10,15H2,1-2H3,(H2,26,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149650
PNG
(2-[3-(3,5-Dibromo-benzylamino)-propylamino]-1H-thi...)
Show SMILES Brc1cc(Br)cc(CNCCCNc2nc3ccsc3c(=O)[nH]2)c1
Show InChI InChI=1S/C16H16Br2N4OS/c17-11-6-10(7-12(18)8-11)9-19-3-1-4-20-16-21-13-2-5-24-14(13)15(23)22-16/h2,5-8,19H,1,3-4,9H2,(H2,20,21,22,23)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124803
PNG
(5-Bromo-2-ethoxy-3-{[3-(4-oxo-1,4-dihydro-quinolin...)
Show SMILES CCOc1c(CNCCCNc2cc(O)c3ccccc3n2)cc(Br)cc1C#N
Show InChI InChI=1S/C22H23BrN4O2/c1-2-29-22-15(13-24)10-17(23)11-16(22)14-25-8-5-9-26-21-12-20(28)18-6-3-4-7-19(18)27-21/h3-4,6-7,10-12,25H,2,5,8-9,14H2,1H3,(H2,26,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149646
PNG
(5-[3-(3,5-Dibromo-benzylamino)-propylamino]-4H-thi...)
Show SMILES Oc1cc(NCCCNCc2cc(Br)cc(Br)c2)nc2ccsc12
Show InChI InChI=1S/C17H17Br2N3OS/c18-12-6-11(7-13(19)8-12)10-20-3-1-4-21-16-9-15(23)17-14(22-16)2-5-24-17/h2,5-9,20H,1,3-4,10H2,(H2,21,22,23)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124825
PNG
(2-[3-(2-Ethoxy-3-hydroxymethyl-5-iodo-benzylamino)...)
Show SMILES CCOc1c(CO)cc(I)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26IN3O3/c1-2-29-22-15(10-17(23)11-16(22)14-27)13-24-8-5-9-25-21-12-20(28)18-6-3-4-7-19(18)26-21/h3-4,6-7,10-12,24,27H,2,5,8-9,13-14H2,1H3,(H2,25,26,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124854
PNG
(2-[3-(3-Chloro-2-ethoxy-5-methoxy-benzylamino)-pro...)
Show SMILES CCOc1c(Cl)cc(OC)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26ClN3O3/c1-3-29-22-15(11-16(28-2)12-18(22)23)14-24-9-6-10-25-21-13-20(27)17-7-4-5-8-19(17)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124835
PNG
(2-[3-(6-Bromo-8-ethyl-1,2,3,4-tetrahydro-quinolin-...)
Show SMILES CCc1cc(Br)cc2C(CCNc12)NCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C23H27BrN4O/c1-2-15-12-16(24)13-18-19(8-11-27-23(15)18)25-9-5-10-26-22-14-21(29)17-6-3-4-7-20(17)28-22/h3-4,6-7,12-14,19,25,27H,2,5,8-11H2,1H3,(H2,26,28,29)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124817
PNG
(2-[3-(3,5-Dibromo-2-ethoxy-benzylamino)-propylamin...)
Show SMILES CCOc1c(Br)cc(Br)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C21H23Br2N3O2/c1-2-28-21-14(10-15(22)11-17(21)23)13-24-8-5-9-25-20-12-19(27)16-6-3-4-7-18(16)26-20/h3-4,6-7,10-12,24H,2,5,8-9,13H2,1H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Isoleucine--tRNA ligase


(Staphylococcus aureus)		BDBM50470911
PNG
(CHEMBL122825)
Show SMILES [H][C@]1(O[C@H]1C[C@H]1CO[C@@H](C\C(C)=C\c2ncc(o2)-c2csc(c2)[N+]([O-])=O)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O
Show InChI InChI=1S/C23H30N2O8S/c1-11(5-19-24-8-18(32-19)15-7-20(25(29)30)34-10-15)4-16-22(28)21(27)14(9-31-16)6-17-23(33-17)12(2)13(3)26/h5,7-8,10,12-14,16-17,21-23,26-28H,4,6,9H2,1-3H3/b11-5+/t12-,13-,14-,16-,17-,21+,22-,23-/m0/s1
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SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus

J Med Chem 39: 3596-600 (1996)


Article DOI: 10.1021/jm950882q
BindingDB Entry DOI: 10.7270/Q2TX3J3G
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124824
PNG
(3-Bromo-4-ethoxy-5-{[3-(4-oxo-1,4-dihydro-quinolin...)
Show SMILES CCOc1c(Br)cc(cc1CNCCCNc1cc(O)c2ccccc2n1)C#N
Show InChI InChI=1S/C22H23BrN4O2/c1-2-29-22-16(10-15(13-24)11-18(22)23)14-25-8-5-9-26-21-12-20(28)17-6-3-4-7-19(17)27-21/h3-4,6-7,10-12,25H,2,5,8-9,14H2,1H3,(H2,26,27,28)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124813
PNG
(2-[3-(3-Bromo-2-ethoxy-5-methylsulfanyl-benzylamin...)
Show SMILES CCOc1c(Br)cc(SC)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26BrN3O2S/c1-3-28-22-15(11-16(29-2)12-18(22)23)14-24-9-6-10-25-21-13-20(27)17-7-4-5-8-19(17)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149649
PNG
(2-[3-(3,5-Dibromo-2-ethoxy-benzylamino)-propylamin...)
Show SMILES CCOc1c(Br)cc(Br)cc1CNCCCNc1nc2ccsc2c(=O)[nH]1
Show InChI InChI=1S/C18H20Br2N4O2S/c1-2-26-15-11(8-12(19)9-13(15)20)10-21-5-3-6-22-18-23-14-4-7-27-16(14)17(25)24-18/h4,7-9,21H,2-3,5-6,10H2,1H3,(H2,22,23,24,25)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124800
PNG
(2-[3-(3-Bromo-2-ethoxy-5-methyl-benzylamino)-propy...)
Show SMILES CCOc1c(Br)cc(C)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26BrN3O2/c1-3-28-22-16(11-15(2)12-18(22)23)14-24-9-6-10-25-21-13-20(27)17-7-4-5-8-19(17)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149630
PNG
(CHEMBL182960 | N-(3,5-Dibromo-benzyl)-N''-(1H-imid...)
Show SMILES Brc1cc(Br)cc(CNCCCNc2nc3ncccc3[nH]2)c1
Show InChI InChI=1S/C16H17Br2N5/c17-12-7-11(8-13(18)9-12)10-19-4-2-6-21-16-22-14-3-1-5-20-15(14)23-16/h1,3,5,7-9,19H,2,4,6,10H2,(H2,20,21,22,23)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124857
PNG
(2-[3-(2-Ethoxy-3-methyl-5-methylsulfanyl-benzylami...)
Show SMILES CCOc1c(C)cc(SC)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C23H29N3O2S/c1-4-28-23-16(2)12-18(29-3)13-17(23)15-24-10-7-11-25-22-14-21(27)19-8-5-6-9-20(19)26-22/h5-6,8-9,12-14,24H,4,7,10-11,15H2,1-3H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124801
PNG
(2-[3-(4,6-Dichloro-indan-1-ylamino)-propylamino]-1...)
Show SMILES Oc1cc(NCCCNC2CCc3c2cc(Cl)cc3Cl)nc2ccccc12
Show InChI InChI=1S/C21H21Cl2N3O/c22-13-10-16-14(17(23)11-13)6-7-18(16)24-8-3-9-25-21-12-20(27)15-4-1-2-5-19(15)26-21/h1-2,4-5,10-12,18,24H,3,6-9H2,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124850
PNG
(2-[3-(5-Bromo-2-ethoxy-3-methyl-benzylamino)-propy...)
Show SMILES CCOc1c(C)cc(Br)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26BrN3O2/c1-3-28-22-15(2)11-17(23)12-16(22)14-24-9-6-10-25-21-13-20(27)18-7-4-5-8-19(18)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124819
PNG
(2-[3-(5-Bromo-2-ethoxy-3-iodo-benzylamino)-propyla...)
Show SMILES CCOc1c(I)cc(Br)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C21H23BrIN3O2/c1-2-28-21-14(10-15(22)11-17(21)23)13-24-8-5-9-25-20-12-19(27)16-6-3-4-7-18(16)26-20/h3-4,6-7,10-12,24H,2,5,8-9,13H2,1H3,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124852
PNG
(2-[3-(5,7-Dichloro-2,3-dihydro-benzofuran-3-ylamin...)
Show SMILES Oc1cc(NCCCNC2COc3c2cc(Cl)cc3Cl)nc2ccccc12
Show InChI InChI=1S/C20H19Cl2N3O2/c21-12-8-14-17(11-27-20(14)15(22)9-12)23-6-3-7-24-19-10-18(26)13-4-1-2-5-16(13)25-19/h1-2,4-5,8-10,17,23H,3,6-7,11H2,(H2,24,25,26)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149643
PNG
(6-[3-(3,5-Dibromo-benzylamino)-propylamino]-7H-thi...)
Show SMILES Oc1cc(NCCCNCc2cc(Br)cc(Br)c2)nc2sccc12
Show InChI InChI=1S/C17H17Br2N3OS/c18-12-6-11(7-13(19)8-12)10-20-3-1-4-21-16-9-15(23)14-2-5-24-17(14)22-16/h2,5-9,20H,1,3-4,10H2,(H2,21,22,23)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50409933
PNG
(CHEMBL2096779)
Show SMILES Brc1cc(Br)c2NCC[C@@H](NCCCNc3nc4ncccc4[nH]3)c2c1 |r|
Show InChI InChI=1S/C18H20Br2N6/c19-11-9-12-14(4-8-22-16(12)13(20)10-11)21-6-2-7-24-18-25-15-3-1-5-23-17(15)26-18/h1,3,5,9-10,14,21-22H,2,4,6-8H2,(H2,23,24,25,26)/t14-/m1/s1
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n/an/a 6.30n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124827
PNG
(2-[3-(3,5-Diiodo-benzylamino)-propylamino]-1H-quin...)
Show SMILES Oc1cc(NCCCNCc2cc(I)cc(I)c2)nc2ccccc12
Show InChI InChI=1S/C19H19I2N3O/c20-14-8-13(9-15(21)10-14)12-22-6-3-7-23-19-11-18(25)16-4-1-2-5-17(16)24-19/h1-2,4-5,8-11,22H,3,6-7,12H2,(H2,23,24,25)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Isoleucine--tRNA ligase


(Staphylococcus aureus)		BDBM50470914
PNG
(CHEMBL120343)
Show SMILES [H][C@]1(O[C@H]1C[C@H]1CO[C@@H](C\C(C)=C\c2ncc(o2)-c2ccc(s2)[N+]([O-])=O)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O
Show InChI InChI=1S/C23H30N2O8S/c1-11(7-19-24-9-17(32-19)18-4-5-20(34-18)25(29)30)6-15-22(28)21(27)14(10-31-15)8-16-23(33-16)12(2)13(3)26/h4-5,7,9,12-16,21-23,26-28H,6,8,10H2,1-3H3/b11-7+/t12-,13-,14-,15-,16-,21+,22-,23-/m0/s1
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SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus NCTC 3571

J Med Chem 39: 3596-600 (1996)


Article DOI: 10.1021/jm950882q
BindingDB Entry DOI: 10.7270/Q2TX3J3G
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124858
PNG
(2-[3-(2-Ethoxy-3-methyl-5-trifluoromethyl-benzylam...)
Show SMILES CCOc1c(C)cc(cc1CNCCCNc1cc(O)c2ccccc2n1)C(F)(F)F
Show InChI InChI=1S/C23H26F3N3O2/c1-3-31-22-15(2)11-17(23(24,25)26)12-16(22)14-27-9-6-10-28-21-13-20(30)18-7-4-5-8-19(18)29-21/h4-5,7-8,11-13,27H,3,6,9-10,14H2,1-2H3,(H2,28,29,30)
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n/an/a 6.80n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124810
PNG
(2-[3-(5-Chloro-2-ethoxy-3-methyl-benzylamino)-prop...)
Show SMILES CCOc1c(C)cc(Cl)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26ClN3O2/c1-3-28-22-15(2)11-17(23)12-16(22)14-24-9-6-10-25-21-13-20(27)18-7-4-5-8-19(18)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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n/an/a 6.80n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Isoleucine--tRNA ligase


(Staphylococcus aureus)		BDBM50470913
PNG
(CHEMBL120798)
Show SMILES [H][C@]1(O[C@H]1C[C@H]1CO[C@@H](C\C(C)=C\c2ncc(o2)-c2cc(cs2)[N+]([O-])=O)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O
Show InChI InChI=1S/C23H30N2O8S/c1-11(5-20-24-8-18(32-20)19-7-15(10-34-19)25(29)30)4-16-22(28)21(27)14(9-31-16)6-17-23(33-17)12(2)13(3)26/h5,7-8,10,12-14,16-17,21-23,26-28H,4,6,9H2,1-3H3/b11-5+/t12-,13-,14-,16-,17-,21+,22-,23-/m0/s1
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n/an/a 6.87n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus

J Med Chem 39: 3596-600 (1996)


Article DOI: 10.1021/jm950882q
BindingDB Entry DOI: 10.7270/Q2TX3J3G
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149648
PNG
(2-[3-(3-Bromo-2-ethoxy-5-methoxy-benzylamino)-prop...)
Show SMILES CCOc1c(Br)cc(OC)cc1CNCCCNc1nc2ccccc2c(=O)[nH]1
Show InChI InChI=1S/C21H25BrN4O3/c1-3-29-19-14(11-15(28-2)12-17(19)22)13-23-9-6-10-24-21-25-18-8-5-4-7-16(18)20(27)26-21/h4-5,7-8,11-12,23H,3,6,9-10,13H2,1-2H3,(H2,24,25,26,27)
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n/an/a 7n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124844
PNG
(2-[3-(2-Ethoxy-3-iodo-5-methyl-benzylamino)-propyl...)
Show SMILES CCOc1c(I)cc(C)cc1CNCCCNc1cc(O)c2ccccc2n1
Show InChI InChI=1S/C22H26IN3O2/c1-3-28-22-16(11-15(2)12-18(22)23)14-24-9-6-10-25-21-13-20(27)17-7-4-5-8-19(17)26-21/h4-5,7-8,11-13,24H,3,6,9-10,14H2,1-2H3,(H2,25,26,27)
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n/an/a 7.20n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124830
PNG
(2-[3-(2-Allyloxy-3,5-dichloro-benzylamino)-propyla...)
Show SMILES Oc1cc(NCCCNCc2cc(Cl)cc(Cl)c2OCC=C)nc2ccccc12
Show InChI InChI=1S/C22H23Cl2N3O2/c1-2-10-29-22-15(11-16(23)12-18(22)24)14-25-8-5-9-26-21-13-20(28)17-6-3-4-7-19(17)27-21/h2-4,6-7,11-13,25H,1,5,8-10,14H2,(H2,26,27,28)
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n/an/a 7.20n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124802
PNG
(2-(3-(6,8-dibromo-3,4-dihydro-2H-chromen-4-ylamino...)
Show SMILES Oc1cc(NCCCNC2CCOc3c(Br)cc(Br)cc23)nc2ccccc12
Show InChI InChI=1S/C21H21Br2N3O2/c22-13-10-15-17(6-9-28-21(15)16(23)11-13)24-7-3-8-25-20-12-19(27)14-4-1-2-5-18(14)26-20/h1-2,4-5,10-12,17,24H,3,6-9H2,(H2,25,26,27)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Isoleucine--tRNA ligase


(Staphylococcus aureus)		BDBM50470912
PNG
(CHEMBL120437)
Show SMILES [H][C@]1(O[C@H]1C[C@H]1CO[C@@H](C\C(C)=C\c2ncc(o2)-c2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O
Show InChI InChI=1S/C25H32N2O8/c1-13(9-22-26-11-21(34-22)16-4-6-18(7-5-16)27(31)32)8-19-24(30)23(29)17(12-33-19)10-20-25(35-20)14(2)15(3)28/h4-7,9,11,14-15,17,19-20,23-25,28-30H,8,10,12H2,1-3H3/b13-9+/t14-,15-,17-,19-,20-,23+,24-,25-/m0/s1
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SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus

J Med Chem 39: 3596-600 (1996)


Article DOI: 10.1021/jm950882q
BindingDB Entry DOI: 10.7270/Q2TX3J3G
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50124848
PNG
(2-[3-(8-Bromo-6-methyl-1,2,3,4-tetrahydro-quinolin...)
Show SMILES Cc1cc(Br)c2NCCC(NCCCNc3cc(O)c4ccccc4n3)c2c1
Show InChI InChI=1S/C22H25BrN4O/c1-14-11-16-18(7-10-26-22(16)17(23)12-14)24-8-4-9-25-21-13-20(28)15-5-2-3-6-19(15)27-21/h2-3,5-6,11-13,18,24,26H,4,7-10H2,1H3,(H2,25,27,28)
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n/an/a 8n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Escherichia coli (strain K12))		BDBM50112575
PNG
(2-[3-(6,8-Dibromo-1,2,3,4-tetrahydro-quinolin-4-yl...)
Show SMILES Oc1cc(NCCCNC2CCNc3c(Br)cc(Br)cc23)nc2ccccc12
Show InChI InChI=1S/C21H22Br2N4O/c22-13-10-15-17(6-9-26-21(15)16(23)11-13)24-7-3-8-25-20-12-19(28)14-4-1-2-5-18(14)27-20/h1-2,4-5,10-12,17,24,26H,3,6-9H2,(H2,25,27,28)
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n/an/a 8n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assay

Bioorg Med Chem Lett 13: 665-8 (2003)


BindingDB Entry DOI: 10.7270/Q2KP81JD
More data for this
Ligand-Target Pair
Methionine--tRNA ligase


(Staphylococcus aureus (strain MW2))		BDBM50149635
PNG
(2-[3-(3,5-Dibromo-benzylamino)-propylamino]-1H-qui...)
Show SMILES Brc1cc(Br)cc(CNCCCNc2nc3ccccc3c(=O)[nH]2)c1
Show InChI InChI=1S/C18H18Br2N4O/c19-13-8-12(9-14(20)10-13)11-21-6-3-7-22-18-23-16-5-2-1-4-15(16)17(25)24-18/h1-2,4-5,8-10,21H,3,6-7,11H2,(H2,22,23,24,25)
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n/an/a 8.10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetase

Bioorg Med Chem Lett 14: 3937-41 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.070
BindingDB Entry DOI: 10.7270/Q2QC02Z9
More data for this
Ligand-Target Pair
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