Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcription factor Jun (Homo sapiens (Human)) | BDBM50092879 (2-Chloro-4-methyl-pyrimidine-5-carboxylic acid (3,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090430 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50062648 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062648 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062648 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090444 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090407 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50092877 (2-Fluoro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062645 (3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062658 (3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062645 (3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090442 (3-Methyl-1-[5-(2-methyl-2H-tetrazol-5-yl)-2-thioph...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090443 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090420 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090431 (3-Methyl-1-[5-(4-methyl-oxazol-2-yl)-2-thiophen-2-...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090406 (1-(5-(4,5-dihydrooxazol-2-yl)-2-(thiophen-2-yl)pyr...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50092882 (2,4-Dichloro-pyrimidine-5-carboxylic acid (3,5-bis...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062658 (3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090449 (2-(4-Chloro-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dihy...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090429 (2-(3,5-Dichloro-phenyl)-4-(3-methyl-2,5-dioxo-2,5-...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090433 (2-(5-Chloro-thiophen-2-yl)-4-(3-methyl-2,5-dioxo-2...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090450 (3-Methyl-1-[5-(5-methyl-[1,3,4]oxadiazol-2-yl)-2-t...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090435 (3-Methyl-1-[5-(3-methyl-isoxazol-5-yl)-2-thiophen-...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50092890 (2-Chloro-pyrimidine-5-carboxylic acid (3,5-bis-tri...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50092872 (2-Chloro-4-ethyl-pyrimidine-5-carboxylic acid (3,5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062669 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50092883 (2-Chloro-4-phenyl-pyrimidine-5-carboxylic acid (3,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090440 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062669 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062663 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062661 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062661 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50092871 (2-Chloro-4-propyl-pyrimidine-5-carboxylic acid (3,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor Jun (Homo sapiens (Human)) | BDBM50092880 (2-Chloro-4-pentafluoroethyl-pyrimidine-5-carboxyli...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | J Med Chem 43: 3995-4004 (2000) BindingDB Entry DOI: 10.7270/Q26M363N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062653 (3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062653 (3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090441 (2-(3-Bromo-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dihyd...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090421 (2-(Furan-2-carbonyl)-4-(3-methyl-2,5-dioxo-2,5-dih...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090426 (2-(4-Fluoro-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dihy...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062663 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062650 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062650 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090409 (2-(4-Methoxy-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dih...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090410 (4-[Methyl-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090432 (2-Cyclopropyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-py...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090415 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090447 (2-tert-Butyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyr...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human)) | BDBM50090408 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells | Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human)) | BDBM50062672 (2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factor | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human)) | BDBM50062656 (3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1 | J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ | |||||||||||
More data for this Ligand-Target Pair |
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