Compile Data Set for Download or QSAR

Found 212 hits with Last Name = 'reballi' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50318633 (3-benzenesulfonyl-8-piperazin-1-ylquinoline | CHEM...) Show SMILES O=S(=O)(c1ccccc1)c1cnc2c(cccc2c1)N1CCNCC1 Show InChI InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50483134 (CHEBI:64156 | Imetit) Show SMILES NC(=N)SCCc1c[nH]cn1 Show InChI InChI=1S/C6H10N4S/c7-6(8)11-2-1-5-3-9-4-10-5/h3-4H,1-2H2,(H3,7,8)(H,9,10)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50019754 (IDALOPIRDINE | LU-AE58054) Show SMILES FC(F)C(F)(F)COc1cccc(CNCCc2c[nH]c3cc(F)ccc23)c1 Show InChI InChI=1S/C20H19F5N2O/c21-15-4-5-17-14(11-27-18(17)9-15)6-7-26-10-13-2-1-3-16(8-13)28-12-20(24,25)19(22)23/h1-5,8-9,11,19,26-27H,6-7,10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Antagonist activity at 5-HT6 receptor (unknown origin)				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517508 (CHEMBL4594107) Show SMILES CC(C)N1CCCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2C(F)(F)F)CC1 Show InChI InChI=1S/C26H39F3N4O2/c1-19(2)32-12-4-11-31(15-16-32)18-25(34)30-24-8-7-22(17-23(24)26(27,28)29)35-21-9-13-33(14-10-21)20-5-3-6-20/h7-8,17,19-21H,3-6,9-16,18H2,1-2H3,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517534 (CHEMBL4476066) Show SMILES Cl.Cl.CCOC(=O)N1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1 Show InChI InChI=1S/C24H36N4O4/c1-2-31-24(30)28-16-14-26(15-17-28)18-23(29)25-19-6-8-21(9-7-19)32-22-10-12-27(13-11-22)20-4-3-5-20/h6-9,20,22H,2-5,10-18H2,1H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517531 (CHEMBL4445638) Show SMILES Cl.Cl.O=C(CN1CCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C21H31N3O2/c25-21(16-23-12-1-2-13-23)22-17-6-8-19(9-7-17)26-20-10-14-24(15-11-20)18-4-3-5-18/h6-9,18,20H,1-5,10-16H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517529 (CHEMBL4587541) Show SMILES Cl.Cl.OCC1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O3.2ClH/c26-16-19-5-2-12-25(19)15-22(27)23-17-6-8-20(9-7-17)28-21-10-13-24(14-11-21)18-3-1-4-18;;/h6-9,18-19,21,26H,1-5,10-16H2,(H,23,27);2*1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50044616 (Cerlapirdine | PF-05212365 | SAM-531 | WAY-262531) Show SMILES CN(C)CCCOc1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H23N3O3S/c1-25(2)13-6-14-28-17-11-12-20-19(15-17)22(24-23-20)29(26,27)21-10-5-8-16-7-3-4-9-18(16)21/h3-5,7-12,15H,6,13-14H2,1-2H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236846 (CHEMBL4080401) Show SMILES O.O.CS(O)(=O)=O.CS(O)(=O)=O.COc1ccc2n(cc(CN3CCNCC3)c2c1)S(=O)(=O)c1ccccc1Br Show InChI InChI=1S/C20H22BrN3O3S/c1-27-16-6-7-19-17(12-16)15(13-23-10-8-22-9-11-23)14-24(19)28(25,26)20-5-3-2-4-18(20)21/h2-7,12,14,22H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant mammalian Geranylgeranyl transferase type I expressed in baculovirus				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517507 (CHEMBL4456037) Show SMILES FC(F)(F)c1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCN(CC1)C1CCC1 Show InChI InChI=1S/C27H39F3N4O2/c28-27(29,30)24-18-23(36-22-10-14-34(15-11-22)21-6-2-7-21)8-9-25(24)31-26(35)19-32-12-3-13-33(17-16-32)20-4-1-5-20/h8-9,18,20-22H,1-7,10-17,19H2,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236844 (CHEMBL4100484) Show SMILES CS(O)(=O)=O.CS(O)(=O)=O.COc1ccc2n(cc(CN3CCN(C)CC3)c2c1)S(=O)(=O)c1ccc(cc1)C(C)C Show InChI InChI=1S/C24H31N3O3S/c1-18(2)19-5-8-22(9-6-19)31(28,29)27-17-20(16-26-13-11-25(3)12-14-26)23-15-21(30-4)7-10-24(23)27/h5-10,15,17-18H,11-14,16H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236780 (CHEMBL4068232) Show SMILES CCN1CCN(Cc2cn(c3ccc(OC)cc23)S(=O)(=O)c2ccc(cc2)C(C)C)CC1 Show InChI InChI=1S/C25H33N3O3S/c1-5-26-12-14-27(15-13-26)17-21-18-28(25-11-8-22(31-4)16-24(21)25)32(29,30)23-9-6-20(7-10-23)19(2)3/h6-11,16,18-19H,5,12-15,17H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517523 (CHEMBL4518550) Show SMILES Cl.Cl.Cc1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCC1 Show InChI InChI=1S/C22H33N3O2/c1-17-15-20(27-19-9-13-25(14-10-19)18-5-4-6-18)7-8-21(17)23-22(26)16-24-11-2-3-12-24/h7-8,15,18-19H,2-6,9-14,16H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236756 (CHEMBL4101284) Show SMILES Cl.Cl.COc1ccc2n(cc(CN3CCCN(C)CC3)c2c1)S(=O)(=O)c1ccc(cc1)C(C)C Show InChI InChI=1S/C25H33N3O3S/c1-19(2)20-6-9-23(10-7-20)32(29,30)28-18-21(17-27-13-5-12-26(3)14-15-27)24-16-22(31-4)8-11-25(24)28/h6-11,16,18-19H,5,12-15,17H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236754 (CHEMBL4082473) Show SMILES O.CS(O)(=O)=O.COc1ccc2n(cc(CN3CCN(C)CC3)c2c1)S(=O)(=O)c1ccccc1Br Show InChI InChI=1S/C21H24BrN3O3S/c1-23-9-11-24(12-10-23)14-16-15-25(20-8-7-17(28-2)13-18(16)20)29(26,27)21-6-4-3-5-19(21)22/h3-8,13,15H,9-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Effective concentration required for partial agonistic activity at Metabotropic glutamate receptor 2; Partial agonist				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236773 (CHEMBL4065437) Show SMILES CN1CCN(Cc2cn(c3ccccc23)S(=O)(=O)c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C20H22BrN3O2S/c1-22-10-12-23(13-11-22)14-16-15-24(20-5-3-2-4-19(16)20)27(25,26)18-8-6-17(21)7-9-18/h2-9,15H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517505 (CHEMBL4521909) Show SMILES C[C@@H]1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1C |r| Show InChI InChI=1S/C23H35N3O2/c1-17-15-21(28-20-10-13-25(14-11-20)19-6-3-7-19)8-9-22(17)24-23(27)16-26-12-4-5-18(26)2/h8-9,15,18-20H,3-7,10-14,16H2,1-2H3,(H,24,27)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517521 (CHEMBL4574463) Show SMILES O=C(NCCN1CCCC1)c1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C23H35N3O2/c27-23(24-13-18-25-14-3-4-15-25)19-7-9-21(10-8-19)28-22-11-16-26(17-12-22)20-5-1-2-6-20/h7-10,20,22H,1-6,11-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517522 (CHEMBL4534815) Show SMILES C[C@@H]1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 |r| Show InChI InChI=1S/C22H33N3O2/c1-17-4-3-13-25(17)16-22(26)23-18-7-9-20(10-8-18)27-21-11-14-24(15-12-21)19-5-2-6-19/h7-10,17,19,21H,2-6,11-16H2,1H3,(H,23,26)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517502 (CHEMBL4439392) Show SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(CN1CCCCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 |r| Show InChI InChI=1S/C23H35N3O2/c27-23(18-25-14-3-1-2-4-15-25)24-19-8-10-21(11-9-19)28-22-12-16-26(17-13-22)20-6-5-7-20/h8-11,20,22H,1-7,12-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517540 (CHEMBL4452215) Show SMILES O=C(NCCN1CCOCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O3/c26-22(23-10-13-24-14-16-27-17-15-24)18-4-6-20(7-5-18)28-21-8-11-25(12-9-21)19-2-1-3-19/h4-7,19,21H,1-3,8-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517527 (CHEMBL4576724) Show SMILES O=C(NCCN1CCCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O2/c26-22(23-12-17-24-13-1-2-14-24)18-6-8-20(9-7-18)27-21-10-15-25(16-11-21)19-4-3-5-19/h6-9,19,21H,1-5,10-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517491 (CHEMBL4468778) Show SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.O=C(NCCN1CCCCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |r| Show InChI InChI=1S/C23H35N3O2/c27-23(24-13-18-25-14-2-1-3-15-25)19-7-9-21(10-8-19)28-22-11-16-26(17-12-22)20-5-4-6-20/h7-10,20,22H,1-6,11-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517506 (CHEMBL4476420) Show SMILES Cl.Cl.Cc1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCCC1 Show InChI InChI=1S/C23H35N3O2/c1-18-16-21(28-20-10-14-26(15-11-20)19-6-5-7-19)8-9-22(18)24-23(27)17-25-12-3-2-4-13-25/h8-9,16,19-20H,2-7,10-15,17H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517532 (CHEMBL4450961) Show SMILES O=C(CN1CCCC1)Nc1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C22H33N3O2/c26-22(17-24-13-3-4-14-24)23-18-7-9-20(10-8-18)27-21-11-15-25(16-12-21)19-5-1-2-6-19/h7-10,19,21H,1-6,11-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517528 (CHEMBL4476745) Show SMILES Cl.Cl.CC(C)N1CCC(CC1)Oc1ccc(NC(=O)CN2CCCCC2)cc1 Show InChI InChI=1S/C21H33N3O2/c1-17(2)24-14-10-20(11-15-24)26-19-8-6-18(7-9-19)22-21(25)16-23-12-4-3-5-13-23/h6-9,17,20H,3-5,10-16H2,1-2H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236832 (CHEMBL4093699) Show SMILES Cl.Cl.CC(C)c1ccc(cc1)S(=O)(=O)n1cc(CN2CCN(C)CC2)c2cc(F)ccc12 Show InChI InChI=1S/C23H28FN3O2S/c1-17(2)18-4-7-21(8-5-18)30(28,29)27-16-19(15-26-12-10-25(3)11-13-26)22-14-20(24)6-9-23(22)27/h4-9,14,16-17H,10-13,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517504 (CHEMBL4464101) Show SMILES Cl.Cl.O=C(CN1CCCCC1)Nc1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C23H35N3O2/c27-23(18-25-14-4-1-5-15-25)24-19-8-10-21(11-9-19)28-22-12-16-26(17-13-22)20-6-2-3-7-20/h8-11,20,22H,1-7,12-18H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517494 (CHEMBL4561912) Show SMILES OCC1CN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CCO1 Show InChI InChI=1S/C22H33N3O4/c26-16-21-14-24(12-13-28-21)15-22(27)23-17-4-6-19(7-5-17)29-20-8-10-25(11-9-20)18-2-1-3-18/h4-7,18,20-21,26H,1-3,8-16H2,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236806 (CHEMBL4100411) Show SMILES COc1ccc2n(cc(CN3CCN(C)CC3)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H25N3O3S/c1-22-10-12-23(13-11-22)15-17-16-24(21-9-8-18(27-2)14-20(17)21)28(25,26)19-6-4-3-5-7-19/h3-9,14,16H,10-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant mammalian Geranylgeranyl transferase type I expressed in baculovirus				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236831 (CHEMBL4077537) Show SMILES Cl.Cl.Brc1ccccc1S(=O)(=O)n1cc(CN2CCNCC2)c2ccccc12 Show InChI InChI=1S/C19H20BrN3O2S/c20-17-6-2-4-8-19(17)26(24,25)23-14-15(13-22-11-9-21-10-12-22)16-5-1-3-7-18(16)23/h1-8,14,21H,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517501 (CHEMBL4578297) Show SMILES Cl.Cl.O=C(CN1CCCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O2/c26-22(17-24-13-2-1-3-14-24)23-18-7-9-20(10-8-18)27-21-11-15-25(16-12-21)19-5-4-6-19/h7-10,19,21H,1-6,11-17H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517519 (CHEMBL4527873) Show SMILES CN(C(=O)CN1CCOCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C22H33N3O3/c1-23(22(26)17-24-13-15-27-16-14-24)18-5-7-20(8-6-18)28-21-9-11-25(12-10-21)19-3-2-4-19/h5-8,19,21H,2-4,9-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236836 (CHEMBL4073586) Show SMILES CS(O)(=O)=O.CS(O)(=O)=O.COc1ccc2n(cc(CN3CCN(C)CC3)c2c1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C21H24FN3O3S/c1-23-9-11-24(12-10-23)14-16-15-25(21-8-5-18(28-2)13-20(16)21)29(26,27)19-6-3-17(22)4-7-19/h3-8,13,15H,9-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517509 (CHEMBL4515325) Show SMILES CC(=O)N1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1 Show InChI InChI=1S/C23H34N4O3/c1-18(28)26-15-13-25(14-16-26)17-23(29)24-19-5-7-21(8-6-19)30-22-9-11-27(12-10-22)20-3-2-4-20/h5-8,20,22H,2-4,9-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236843 (CHEMBL4105377) Show SMILES Cl.Cl.COc1ccc2n(cc(CN3CCNCC3)c2c1)S(=O)(=O)c1ccc(cc1)C(C)C Show InChI InChI=1S/C23H29N3O3S/c1-17(2)18-4-7-21(8-5-18)30(27,28)26-16-19(15-25-12-10-24-11-13-25)22-14-20(29-3)6-9-23(22)26/h4-9,14,16-17,24H,10-13,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236792 (CHEMBL4083289) Show SMILES COc1ccc2n(cc(CN3CCCN(C)CC3)c2c1)S(=O)(=O)c1ccccc1Br Show InChI InChI=1S/C22H26BrN3O3S/c1-24-10-5-11-25(13-12-24)15-17-16-26(21-9-8-18(29-2)14-19(17)21)30(27,28)22-7-4-3-6-20(22)23/h3-4,6-9,14,16H,5,10-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517499 (CHEMBL4465570) Show SMILES CN(C)CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C19H29N3O2/c1-21(2)14-19(23)20-15-6-8-17(9-7-15)24-18-10-12-22(13-11-18)16-4-3-5-16/h6-9,16,18H,3-5,10-14H2,1-2H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236833 (CHEMBL4062687) Show SMILES Cl.Cl.CN1CCN(Cc2cn(c3ccccc23)S(=O)(=O)c2ccccc2)CC1 Show InChI InChI=1S/C20H23N3O2S/c1-21-11-13-22(14-12-21)15-17-16-23(20-10-6-5-9-19(17)20)26(24,25)18-7-3-2-4-8-18/h2-10,16H,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236777 (CHEMBL4097459) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)n1cc(CN2CCN(C)CC2)c2ccccc12 Show InChI InChI=1S/C23H29N3O2S/c1-18(2)19-8-10-21(11-9-19)29(27,28)26-17-20(22-6-4-5-7-23(22)26)16-25-14-12-24(3)13-15-25/h4-11,17-18H,12-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517511 (CHEMBL4439589) Show SMILES Cl.Cl.OC1CCN(CC(=O)Nc2ccc(OC3CCN(CC3)C3CCC3)cc2)CC1 Show InChI InChI=1S/C22H33N3O3/c26-19-8-12-24(13-9-19)16-22(27)23-17-4-6-20(7-5-17)28-21-10-14-25(15-11-21)18-2-1-3-18/h4-7,18-19,21,26H,1-3,8-16H2,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236821 (CHEMBL4075502) Show SMILES CCN1CCN(Cc2cn(c3ccc(OC)cc23)S(=O)(=O)c2ccccc2Br)CC1 Show InChI InChI=1S/C22H26BrN3O3S/c1-3-24-10-12-25(13-11-24)15-17-16-26(21-9-8-18(29-2)14-19(17)21)30(27,28)22-7-5-4-6-20(22)23/h4-9,14,16H,3,10-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236834 (CHEMBL4073450) Show SMILES CS(O)(=O)=O.CS(O)(=O)=O.COc1ccc2n(cc(CN3CCNCC3)c2c1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN3O3S/c1-27-17-4-7-20-19(12-17)15(13-23-10-8-22-9-11-23)14-24(20)28(25,26)18-5-2-16(21)3-6-18/h2-7,12,14,22H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236803 (CHEMBL4095054) Show SMILES O=S(=O)(c1ccccc1)n1cc(CN2CCNCC2)c2ccccc12 Show InChI InChI=1S/C19H21N3O2S/c23-25(24,17-6-2-1-3-7-17)22-15-16(14-21-12-10-20-11-13-21)18-8-4-5-9-19(18)22/h1-9,15,20H,10-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236801 (CHEMBL4092681) Show SMILES COc1ccc2n(cc(CN3CCN(C)CC3)c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C25H27N3O3S/c1-26-12-14-27(15-13-26)17-20-18-28(24-11-10-21(31-2)16-23(20)24)32(29,30)25-9-5-7-19-6-3-4-8-22(19)25/h3-11,16,18H,12-15,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Inhibitory activity against fucosyltransferase (FucT V) in the presence of 1 mM fucosyl acceptor N-acetyllactosamine				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236839 (CHEMBL4083893) Show SMILES Cl.Cl.COc1ccc2n(cc(CN3CCCN(C)CC3)c2c1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H26FN3O3S/c1-24-10-3-11-25(13-12-24)15-17-16-26(22-9-6-19(29-2)14-21(17)22)30(27,28)20-7-4-18(23)5-8-20/h4-9,14,16H,3,10-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236810 (CHEMBL4103281) Show SMILES CN1CCN(Cc2cn(c3ccccc23)S(=O)(=O)c2ccccc2F)CC1 Show InChI InChI=1S/C20H22FN3O2S/c1-22-10-12-23(13-11-22)14-16-15-24(19-8-4-2-6-17(16)19)27(25,26)20-9-5-3-7-18(20)21/h2-9,15H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517512 (CHEMBL4564463) Show SMILES Cl.Cl.CC(C)N1CCC(CC1)Oc1ccc(NC(=O)CN2CCOCC2)cc1 Show InChI InChI=1S/C20H31N3O3/c1-16(2)23-9-7-19(8-10-23)26-18-5-3-17(4-6-18)21-20(24)15-22-11-13-25-14-12-22/h3-6,16,19H,7-15H2,1-2H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50517497 (CHEMBL4593911) Show SMILES Cl.Cl.O=C(CN1CCOCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C21H31N3O3/c25-21(16-23-12-14-26-15-13-23)22-17-4-6-19(7-5-17)27-20-8-10-24(11-9-20)18-2-1-3-18/h4-7,18,20H,1-3,8-16H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 62: 1203-1217 (2019) Article DOI: 10.1021/acs.jmedchem.8b01280 BindingDB Entry DOI: 10.7270/Q2XD152G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50236812 (CHEMBL4070284) Show SMILES CN1CCN(Cc2cn(c3ccccc23)S(=O)(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C20H22FN3O2S/c1-22-10-12-23(13-11-22)14-16-15-24(20-5-3-2-4-19(16)20)27(25,26)18-8-6-17(21)7-9-18/h2-9,15H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins				J Med Chem 60: 1843-1859 (2017) Article DOI: 10.1021/acs.jmedchem.6b01662 BindingDB Entry DOI: 10.7270/Q27S7R1X
					More data for this Ligand-Target Pair

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