Compile Data Set for Download or QSAR

Found 231 hits with Last Name = 'salgado' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50326432 (CHEMBL1242995 | N-ethyl-4-methyl-5-(2-(4-(piperazi...) Show SMILES CCNc1nc(C)c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1 Show InChI InChI=1S/C20H25N7S/c1-3-22-20-24-14(2)18(28-20)17-8-9-23-19(26-17)25-15-4-6-16(7-5-15)27-12-10-21-11-13-27/h4-9,21H,3,10-13H2,1-2H3,(H,22,24)(H,23,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Cancer Research Centre (CNIO) Curated by ChEMBL					Assay Description Inhibition of FLT3				J Med Chem 53: 6618-28 (2010) Article DOI: 10.1021/jm1005513 BindingDB Entry DOI: 10.7270/Q2Z038CP
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161942 (US9682991, 5) Show SMILES CN(C)C1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H26F3N7O2/c1-29(2)15-7-9-31(10-8-15)20-17-18(33-12-11-30(17)3)21-27-26-19(32(21)28-20)14-5-4-6-16(13-14)34-22(23,24)25/h4-6,13,15H,7-12H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161946 (US9682991, 7) Show SMILES CN1CCOc2c1c(NCC1CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C19H19F3N6O2/c1-27-7-8-29-15-14(27)16(23-10-11-5-6-11)26-28-17(24-25-18(15)28)12-3-2-4-13(9-12)30-19(20,21)22/h2-4,9,11H,5-8,10H2,1H3,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161950 (US9682991, 9) Show SMILES CN1CCOc2c1c(NCc1ccc(F)cc1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H18F4N6O2/c1-31-9-10-33-18-17(31)19(27-12-13-5-7-15(23)8-6-13)30-32-20(28-29-21(18)32)14-3-2-4-16(11-14)34-22(24,25)26/h2-8,11H,9-10,12H2,1H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162044 (US9682991, 98) Show SMILES CN(CCN1CCOCC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H26F3N7O3/c1-29-8-13-34-18-17(29)20(30(2)6-7-31-9-11-33-12-10-31)28-32-19(26-27-21(18)32)15-4-3-5-16(14-15)35-22(23,24)25/h3-5,14H,6-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162047 (US9682991, 101) Show SMILES FC(F)(F)Oc1cccc(c1)-c1nnc2c3OCCOc3c(nn12)N1CCCCC1 Show InChI InChI=1S/C19H18F3N5O3/c20-19(21,22)30-13-6-4-5-12(11-13)16-23-24-17-14-15(29-10-9-28-14)18(25-27(16)17)26-7-2-1-3-8-26/h4-6,11H,1-3,7-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162048 (US9682991, 102) Show SMILES FC(F)(F)Oc1cccc(c1)-c1nnc2c3OCCOc3c(NCC3CC3)nn12 Show InChI InChI=1S/C18H16F3N5O3/c19-18(20,21)29-12-3-1-2-11(8-12)16-23-24-17-14-13(27-6-7-28-14)15(25-26(16)17)22-9-10-4-5-10/h1-3,8,10H,4-7,9H2,(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM162048 (US9682991, 102) Show SMILES FC(F)(F)Oc1cccc(c1)-c1nnc2c3OCCOc3c(NCC3CC3)nn12 Show InChI InChI=1S/C18H16F3N5O3/c19-18(20,21)29-12-3-1-2-11(8-12)16-23-24-17-14-13(27-6-7-28-14)15(25-26(16)17)22-9-10-4-5-10/h1-3,8,10H,4-7,9H2,(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162049 (US9682991, 103) Show SMILES CN1CCOc2c1c(NC1CC[N+](C)([O-])CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N7O3/c1-29-8-11-33-17-16(29)18(25-14-6-9-31(2,32)10-7-14)28-30-19(26-27-20(17)30)13-4-3-5-15(12-13)34-21(22,23)24/h3-5,12,14H,6-11H2,1-2H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161938 (US9682991, 2) Show SMILES CN1CCC(CC1)Nc1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N7O2/c1-29-8-6-14(7-9-29)25-18-16-17(32-11-10-30(16)2)20-27-26-19(31(20)28-18)13-4-3-5-15(12-13)33-21(22,23)24/h3-5,12,14H,6-11H2,1-2H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161946 (US9682991, 7) Show SMILES CN1CCOc2c1c(NCC1CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C19H19F3N6O2/c1-27-7-8-29-15-14(27)16(23-10-11-5-6-11)26-28-17(24-25-18(15)28)12-3-2-4-13(9-12)30-19(20,21)22/h2-4,9,11H,5-8,10H2,1H3,(H,23,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161956 (US9682991, 11) Show SMILES CCN1CCOc2c1c(NCC1CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C20H21F3N6O2/c1-2-28-8-9-30-16-15(28)17(24-11-12-6-7-12)27-29-18(25-26-19(16)29)13-4-3-5-14(10-13)31-20(21,22)23/h3-5,10,12H,2,6-9,11H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161957 (US9682991, 12) Show SMILES CCN1CCOc2c1c(NCC1CCN(C)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H28F3N7O2/c1-3-32-11-12-34-19-18(32)20(27-14-15-7-9-31(2)10-8-15)30-33-21(28-29-22(19)33)16-5-4-6-17(13-16)35-23(24,25)26/h4-6,13,15H,3,7-12,14H2,1-2H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161967 (US9682991, 16) Show SMILES CN1CCC(CNc2nn3c(nnc3c3OCCN(C)c23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H26F3N7O2/c1-30-8-6-14(7-9-30)13-26-19-17-18(33-11-10-31(17)2)21-28-27-20(32(21)29-19)15-4-3-5-16(12-15)34-22(23,24)25/h3-5,12,14H,6-11,13H2,1-2H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161968 (US9682991, 17) Show SMILES CN1CCC(CNc2nn3c(nnc3c3N(C)CCOc23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H26F3N7O2/c1-30-8-6-14(7-9-30)13-26-19-18-17(31(2)10-11-33-18)21-28-27-20(32(21)29-19)15-4-3-5-16(12-15)34-22(23,24)25/h3-5,12,14H,6-11,13H2,1-2H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161970 (US9682991, 19) Show SMILES CN1CCOc2c1c(N[C@H]1CC[C@H](O)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 |r,wU:12.13,wD:9.9,(-4.94,3.47,;-3.61,4.24,;-3.61,5.78,;-2.27,6.55,;-.94,5.78,;-.94,4.24,;-2.27,3.47,;-2.27,1.93,;-3.61,1.16,;-3.61,-.38,;-4.94,-1.15,;-4.94,-2.69,;-3.61,-3.46,;-3.61,-5,;-2.27,-2.69,;-2.27,-1.15,;-.94,1.16,;.39,1.93,;1.86,1.45,;2.76,2.7,;1.86,3.94,;.39,3.47,;2.63,.12,;4.17,.12,;4.94,-1.21,;4.17,-2.55,;2.63,-2.55,;1.86,-3.88,;2.63,-5.22,;3.4,-6.55,;4.17,-5.22,;1.86,-6.55,;1.86,-1.21,)| Show InChI InChI=1S/C21H23F3N6O3/c1-29-9-10-32-17-16(29)18(25-13-5-7-14(31)8-6-13)28-30-19(26-27-20(17)30)12-3-2-4-15(11-12)33-21(22,23)24/h2-4,11,13-14,31H,5-10H2,1H3,(H,25,28)/t13-,14-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161972 (US9682991, 21) Show SMILES CN1CCOc2c1c(NCCCO)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C18H19F3N6O3/c1-26-7-9-29-14-13(26)15(22-6-3-8-28)25-27-16(23-24-17(14)27)11-4-2-5-12(10-11)30-18(19,20)21/h2,4-5,10,28H,3,6-9H2,1H3,(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161974 (US9682991, 23) Show SMILES CN1CCOc2c1c(NC1CCOCC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C20H21F3N6O3/c1-28-7-10-31-16-15(28)17(24-13-5-8-30-9-6-13)27-29-18(25-26-19(16)29)12-3-2-4-14(11-12)32-20(21,22)23/h2-4,11,13H,5-10H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161974 (US9682991, 23) Show SMILES CN1CCOc2c1c(NC1CCOCC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C20H21F3N6O3/c1-28-7-10-31-16-15(28)17(24-13-5-8-30-9-6-13)27-29-18(25-26-19(16)29)12-3-2-4-14(11-12)32-20(21,22)23/h2-4,11,13H,5-10H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161977 (US9682991, 26) Show SMILES CN1CCOc2c1c(NCCc1cccnc1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H20F3N7O2/c1-31-10-11-33-18-17(31)19(27-9-7-14-4-3-8-26-13-14)30-32-20(28-29-21(18)32)15-5-2-6-16(12-15)34-22(23,24)25/h2-6,8,12-13H,7,9-11H2,1H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161978 (US9682991, 27) Show SMILES CN1CCN(CCNc2nn3c(nnc3c3OCCN(C)c23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C22H27F3N8O2/c1-30-8-10-32(11-9-30)7-6-26-19-17-18(34-13-12-31(17)2)21-28-27-20(33(21)29-19)15-4-3-5-16(14-15)35-22(23,24)25/h3-5,14H,6-13H2,1-2H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161980 (US9682991, 29) Show SMILES CN1CCOc2c1c(NCCN1CCOCC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N7O3/c1-29-7-12-33-17-16(29)18(25-5-6-30-8-10-32-11-9-30)28-31-19(26-27-20(17)31)14-3-2-4-15(13-14)34-21(22,23)24/h2-4,13H,5-12H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161983 (US9682991, 32) Show SMILES CN1CCC(CNc2nn3c(nnc3c3OCCN(C)c23)-c2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C22H26F3N7O/c1-30-8-6-14(7-9-30)13-26-19-17-18(33-11-10-31(17)2)21-28-27-20(32(21)29-19)15-4-3-5-16(12-15)22(23,24)25/h3-5,12,14H,6-11,13H2,1-2H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161983 (US9682991, 32) Show SMILES CN1CCC(CNc2nn3c(nnc3c3OCCN(C)c23)-c2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C22H26F3N7O/c1-30-8-6-14(7-9-30)13-26-19-17-18(33-11-10-31(17)2)21-28-27-20(32(21)29-19)15-4-3-5-16(12-15)22(23,24)25/h3-5,12,14H,6-11,13H2,1-2H3,(H,26,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161985 (US9682991, 34) Show SMILES CN(C)c1cccc(c1)-c1nnc2c3OCCN(C)c3c(NCC3CCN(C)CC3)nn12 Show InChI InChI=1S/C23H32N8O/c1-28(2)18-7-5-6-17(14-18)22-25-26-23-20-19(30(4)12-13-32-20)21(27-31(22)23)24-15-16-8-10-29(3)11-9-16/h5-7,14,16H,8-13,15H2,1-4H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161986 (US9682991, 35) Show SMILES CN([C@H]1CC[C@H](O)CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 |r,wU:2.1,wD:5.5,(-6.57,1.15,;-5.24,.38,;-5.24,-1.16,;-3.91,-1.93,;-3.91,-3.47,;-5.24,-4.23,;-5.24,-5.77,;-6.57,-3.47,;-6.57,-1.93,;-3.91,1.15,;-2.57,.39,;-1.24,1.15,;.23,.68,;1.13,1.92,;.23,3.17,;-1.24,2.69,;-2.57,3.46,;-2.57,5,;-3.91,5.77,;-5.24,5,;-5.24,3.46,;-6.57,2.69,;-3.91,2.69,;.62,-.81,;-.46,-1.9,;-.07,-3.38,;1.42,-3.78,;2.51,-2.69,;4,-3.09,;5.09,-2,;6.57,-2.4,;4.69,-.52,;5.49,-3.49,;2.11,-1.21,)| Show InChI InChI=1S/C22H25F3N6O3/c1-29-10-11-33-18-17(29)20(30(2)14-6-8-15(32)9-7-14)28-31-19(26-27-21(18)31)13-4-3-5-16(12-13)34-22(23,24)25/h3-5,12,14-15,32H,6-11H2,1-2H3/t14-,15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161986 (US9682991, 35) Show SMILES CN([C@H]1CC[C@H](O)CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 |r,wU:2.1,wD:5.5,(-6.57,1.15,;-5.24,.38,;-5.24,-1.16,;-3.91,-1.93,;-3.91,-3.47,;-5.24,-4.23,;-5.24,-5.77,;-6.57,-3.47,;-6.57,-1.93,;-3.91,1.15,;-2.57,.39,;-1.24,1.15,;.23,.68,;1.13,1.92,;.23,3.17,;-1.24,2.69,;-2.57,3.46,;-2.57,5,;-3.91,5.77,;-5.24,5,;-5.24,3.46,;-6.57,2.69,;-3.91,2.69,;.62,-.81,;-.46,-1.9,;-.07,-3.38,;1.42,-3.78,;2.51,-2.69,;4,-3.09,;5.09,-2,;6.57,-2.4,;4.69,-.52,;5.49,-3.49,;2.11,-1.21,)| Show InChI InChI=1S/C22H25F3N6O3/c1-29-10-11-33-18-17(29)20(30(2)14-6-8-15(32)9-7-14)28-31-19(26-27-21(18)31)13-4-3-5-16(12-13)34-22(23,24)25/h3-5,12,14-15,32H,6-11H2,1-2H3/t14-,15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161990 (US9682991, 39) Show SMILES CC1COc2c(N1C)c(NCC1CCN(C)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H28F3N7O2/c1-14-13-34-19-18(32(14)3)20(27-12-15-7-9-31(2)10-8-15)30-33-21(28-29-22(19)33)16-5-4-6-17(11-16)35-23(24,25)26/h4-6,11,14-15H,7-10,12-13H2,1-3H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161991 (US9682991, 40) Show SMILES CC1CN(C)c2c(NCC3CCN(C)CC3)nn3c(nnc3c2O1)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H28F3N7O2/c1-14-13-32(3)18-19(34-14)22-29-28-21(16-5-4-6-17(11-16)35-23(24,25)26)33(22)30-20(18)27-12-15-7-9-31(2)10-8-15/h4-6,11,14-15H,7-10,12-13H2,1-3H3,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161991 (US9682991, 40) Show SMILES CC1CN(C)c2c(NCC3CCN(C)CC3)nn3c(nnc3c2O1)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H28F3N7O2/c1-14-13-32(3)18-19(34-14)22-29-28-21(16-5-4-6-17(11-16)35-23(24,25)26)33(22)30-20(18)27-12-15-7-9-31(2)10-8-15/h4-6,11,14-15H,7-10,12-13H2,1-3H3,(H,27,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161992 (US9682991, 41) Show SMILES CN1CCC(CNc2nn3c(nnc3c3OCCOc23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C21H23F3N6O3/c1-29-7-5-13(6-8-29)12-25-18-16-17(32-10-9-31-16)20-27-26-19(30(20)28-18)14-3-2-4-15(11-14)33-21(22,23)24/h2-4,11,13H,5-10,12H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161994 (US9682991, 43) Show SMILES CN1CCOc2c1c(NCC1CC[C@H](O)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 |r,wD:13.14,(-4.57,1.93,;-3.24,2.69,;-3.24,4.23,;-1.91,5,;-.57,4.23,;-.57,2.69,;-1.91,1.93,;-1.91,.38,;-3.24,-.38,;-3.24,-1.93,;-4.57,-2.69,;-4.57,-4.23,;-5.91,-5,;-7.24,-4.23,;-8.57,-5,;-7.24,-2.69,;-5.91,-1.92,;-.57,-.38,;.76,.38,;2.23,-.09,;3.13,1.15,;2.23,2.4,;.76,1.93,;2.62,-1.58,;1.54,-2.67,;1.93,-4.15,;3.42,-4.55,;4.51,-3.46,;6,-3.86,;7.09,-2.77,;8.57,-3.17,;6.69,-1.29,;8.18,-1.69,;4.11,-1.98,)| Show InChI InChI=1S/C22H25F3N6O3/c1-30-9-10-33-18-17(30)19(26-12-13-5-7-15(32)8-6-13)29-31-20(27-28-21(18)31)14-3-2-4-16(11-14)34-22(23,24)25/h2-4,11,13,15,32H,5-10,12H2,1H3,(H,26,29)/t13?,15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161994 (US9682991, 43) Show SMILES CN1CCOc2c1c(NCC1CC[C@H](O)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 |r,wD:13.14,(-4.57,1.93,;-3.24,2.69,;-3.24,4.23,;-1.91,5,;-.57,4.23,;-.57,2.69,;-1.91,1.93,;-1.91,.38,;-3.24,-.38,;-3.24,-1.93,;-4.57,-2.69,;-4.57,-4.23,;-5.91,-5,;-7.24,-4.23,;-8.57,-5,;-7.24,-2.69,;-5.91,-1.92,;-.57,-.38,;.76,.38,;2.23,-.09,;3.13,1.15,;2.23,2.4,;.76,1.93,;2.62,-1.58,;1.54,-2.67,;1.93,-4.15,;3.42,-4.55,;4.51,-3.46,;6,-3.86,;7.09,-2.77,;8.57,-3.17,;6.69,-1.29,;8.18,-1.69,;4.11,-1.98,)| Show InChI InChI=1S/C22H25F3N6O3/c1-30-9-10-33-18-17(30)19(26-12-13-5-7-15(32)8-6-13)29-31-20(27-28-21(18)31)14-3-2-4-16(11-14)34-22(23,24)25/h2-4,11,13,15,32H,5-10,12H2,1H3,(H,26,29)/t13?,15-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161997 (US9682991, 48) Show SMILES CN1CCOc2c1c(nn1c(nnc21)-c1cccc(OC(F)(F)F)c1)N1CCC2(CC(N)C2)CC1 Show InChI InChI=1S/C23H26F3N7O2/c1-31-9-10-34-18-17(31)20(32-7-5-22(6-8-32)12-15(27)13-22)30-33-19(28-29-21(18)33)14-3-2-4-16(11-14)35-23(24,25)26/h2-4,11,15H,5-10,12-13,27H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162053 (US9682991, 49) Show SMILES CN1CCOc2c1c(NC1CC3(C1)CCNCC3)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H26F3N7O2/c1-32-9-10-34-18-17(32)19(28-15-12-22(13-15)5-7-27-8-6-22)31-33-20(29-30-21(18)33)14-3-2-4-16(11-14)35-23(24,25)26/h2-4,11,15,27H,5-10,12-13H2,1H3,(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161998 (US9682991, 50) Show SMILES CC1COc2c(N1C)c(nn1c(nnc21)-c1cccc(OC(F)(F)F)c1)N1CCC2(CC(N)C2)CC1 Show InChI InChI=1S/C24H28F3N7O2/c1-14-13-35-19-18(32(14)2)21(33-8-6-23(7-9-33)11-16(28)12-23)31-34-20(29-30-22(19)34)15-4-3-5-17(10-15)36-24(25,26)27/h3-5,10,14,16H,6-9,11-13,28H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162001 (US9682991, 54) Show SMILES CN1CCOc2c1c(NCC13CCN(CC1)C3)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H24F3N7O2/c1-30-9-10-33-17-16(30)18(26-12-21-5-7-31(13-21)8-6-21)29-32-19(27-28-20(17)32)14-3-2-4-15(11-14)34-22(23,24)25/h2-4,11H,5-10,12-13H2,1H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162002 (US9682991, 55) Show SMILES CN1CCOc2c1c(nn1c(nnc21)-c1cccc(OC(F)(F)F)c1)N1CCC(CN)CC1 Show InChI InChI=1S/C21H24F3N7O2/c1-29-9-10-32-17-16(29)19(30-7-5-13(12-25)6-8-30)28-31-18(26-27-20(17)31)14-3-2-4-15(11-14)33-21(22,23)24/h2-4,11,13H,5-10,12,25H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM162002 (US9682991, 55) Show SMILES CN1CCOc2c1c(nn1c(nnc21)-c1cccc(OC(F)(F)F)c1)N1CCC(CN)CC1 Show InChI InChI=1S/C21H24F3N7O2/c1-29-9-10-32-17-16(29)19(30-7-5-13(12-25)6-8-30)28-31-18(26-27-20(17)31)14-3-2-4-15(11-14)33-21(22,23)24/h2-4,11,13H,5-10,12,25H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162055 (US9682991, 56) Show SMILES CN1CCOc2c1c(NCC1CCNCC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N7O2/c1-30-9-10-32-17-16(30)18(26-12-13-5-7-25-8-6-13)29-31-19(27-28-20(17)31)14-3-2-4-15(11-14)33-21(22,23)24/h2-4,11,13,25H,5-10,12H2,1H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162003 (US9682991, 57) Show SMILES CN1CCOc2c(nn3c(nnc3c12)-c1cccc(OC(F)(F)F)c1)N1CCC(CN)CC1 Show InChI InChI=1S/C21H24F3N7O2/c1-29-9-10-32-17-16(29)19-27-26-18(14-3-2-4-15(11-14)33-21(22,23)24)31(19)28-20(17)30-7-5-13(12-25)6-8-30/h2-4,11,13H,5-10,12,25H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162056 (US9682991, 58) Show SMILES CN1CCOc2c(NCC3CCNCC3)nn3c(nnc3c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N7O2/c1-30-9-10-32-17-16(30)20-28-27-19(14-3-2-4-15(11-14)33-21(22,23)24)31(20)29-18(17)26-12-13-5-7-25-8-6-13/h2-4,11,13,25H,5-10,12H2,1H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162004 (US9682991, 59) Show SMILES CN1CCOc2c1c(NCC1CC3(C1)CCNCC3)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C24H28F3N7O2/c1-33-9-10-35-19-18(33)20(29-14-15-12-23(13-15)5-7-28-8-6-23)32-34-21(30-31-22(19)34)16-3-2-4-17(11-16)36-24(25,26)27/h2-4,11,15,28H,5-10,12-14H2,1H3,(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM162004 (US9682991, 59) Show SMILES CN1CCOc2c1c(NCC1CC3(C1)CCNCC3)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C24H28F3N7O2/c1-33-9-10-35-19-18(33)20(29-14-15-12-23(13-15)5-7-28-8-6-23)32-34-21(30-31-22(19)34)16-3-2-4-17(11-16)36-24(25,26)27/h2-4,11,15,28H,5-10,12-14H2,1H3,(H,29,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162005 (US9682991, 60) Show SMILES CN1CCOc2c1c(nn1c(nnc21)-c1cccc(OC(F)(F)F)c1)N1CCCC2(CCCN2)CC1 Show InChI InChI=1S/C24H28F3N7O2/c1-32-13-14-35-19-18(32)21(33-11-4-8-23(9-12-33)7-3-10-28-23)31-34-20(29-30-22(19)34)16-5-2-6-17(15-16)36-24(25,26)27/h2,5-6,15,28H,3-4,7-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162057 (US9682991, 61) Show SMILES CN1CCCC11CCCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H30F3N7O2/c1-32-14-15-36-20-19(32)22(34-12-5-9-24(10-13-34)8-4-11-33(24)2)31-35-21(29-30-23(20)35)17-6-3-7-18(16-17)37-25(26,27)28/h3,6-7,16H,4-5,8-15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162006 (US9682991, 62) Show SMILES CNC1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N7O2/c1-25-14-6-8-30(9-7-14)19-16-17(32-11-10-29(16)2)20-27-26-18(31(20)28-19)13-4-3-5-15(12-13)33-21(22,23)24/h3-5,12,14,25H,6-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM162006 (US9682991, 62) Show SMILES CNC1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C21H24F3N7O2/c1-25-14-6-8-30(9-7-14)19-16-17(32-11-10-29(16)2)20-27-26-18(31(20)28-19)13-4-3-5-15(12-13)33-21(22,23)24/h3-5,12,14,25H,6-11H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM162007 (US9682991, 63) Show SMILES CNCC1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H26F3N7O2/c1-26-13-14-6-8-31(9-7-14)20-17-18(33-11-10-30(17)2)21-28-27-19(32(21)29-20)15-4-3-5-16(12-15)34-22(23,24)25/h3-5,12,14,26H,6-11,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM162007 (US9682991, 63) Show SMILES CNCC1CCN(CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C22H26F3N7O2/c1-26-13-14-6-8-31(9-7-14)20-17-18(33-11-10-30(17)2)21-28-27-19(32(21)29-20)15-4-3-5-16(12-15)34-22(23,24)25/h3-5,12,14,26H,6-11,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 231 total )  |  Next  |  Last  >>

Jump to: