Compile Data Set for Download or QSAR

Found 1270 hits with Last Name = 'wen' and Initial = 'w'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50065136 (CHEMBL81455 | N-(2-Azepan-1-yl-ethyl)-4-iodo-N-met...) Show SMILES CN(CCN1CCCCCC1)S(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C15H23IN2O2S/c1-17(12-13-18-10-4-2-3-5-11-18)21(19,20)15-8-6-14(16)7-9-15/h6-9H,2-5,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The George Washington University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranes				J Med Chem 41: 2445-50 (1998) Article DOI: 10.1021/jm9800447 BindingDB Entry DOI: 10.7270/Q27P8XHM
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000066 ((2-Azepan-1-yl-ethyl)-[2-(3,4-dichloro-phenyl)-eth...) Show SMILES CN(CCN1CCCCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H26Cl2N2/c1-20(12-13-21-9-4-2-3-5-10-21)11-8-15-6-7-16(18)17(19)14-15/h6-7,14H,2-5,8-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50065134 (CHEMBL309983 | N-(2-Azepan-1-yl-ethyl)-4-bromo-N-m...) Show SMILES CN(CCN1CCCCCC1)S(=O)(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C15H23BrN2O2S/c1-17(12-13-18-10-4-2-3-5-11-18)21(19,20)15-8-6-14(16)7-9-15/h6-9H,2-5,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The George Washington University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranes				J Med Chem 41: 2445-50 (1998) Article DOI: 10.1021/jm9800447 BindingDB Entry DOI: 10.7270/Q27P8XHM
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000068 (CHEMBL142700 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...) Show SMILES CN(CCN1CCCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H24Cl2N2/c1-19(11-12-20-8-3-2-4-9-20)10-7-14-5-6-15(17)16(18)13-14/h5-6,13H,2-4,7-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50037480 ((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...) Show SMILES CCCCCN1CC[C@]2(C)[C@H](C)C1Cc1ccc(O)cc21 |TLB:4:5:10:20.14.13,THB:19:20:10:5.7.6| Show InChI InChI=1S/C19H29NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h7-8,13-14,18,21H,4-6,9-12H2,1-3H3/t14-,18?,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000776 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperaz...) Show SMILES CCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C15H22Cl2N2/c1-2-6-18-8-10-19(11-9-18)7-5-13-3-4-14(16)15(17)12-13/h3-4,12H,2,5-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068455 (CHEMBL342809 | {4-Oxo-4-[4-(3-phenyl-propyl)-piper...) Show SMILES CC(C)(C)OC(=O)NCCCC(=O)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C22H35N3O3/c1-22(2,3)28-21(27)23-13-7-12-20(26)25-17-15-24(16-18-25)14-8-11-19-9-5-4-6-10-19/h4-6,9-10H,7-8,11-18H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000078 ((3,4-Dichloro-benzyl)-methyl-(2-pyrrolidin-1-yl-et...) Show SMILES CN(CCN1CCCC1)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H20Cl2N2/c1-17(8-9-18-6-2-3-7-18)11-12-4-5-13(15)14(16)10-12/h4-5,10H,2-3,6-9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000773 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...) Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125092 (1-Benzyl-4-(3-methoxy-benzyl)-piperazine | CHEMBL1...) Show SMILES COc1cccc(CN2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C19H24N2O/c1-22-19-9-5-8-18(14-19)16-21-12-10-20(11-13-21)15-17-6-3-2-4-7-17/h2-9,14H,10-13,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000773 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...) Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454823 (CHEMBL3084910) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1Cl)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24ClNO/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14H2,1H3/t16-,17+,18+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454830 (CHEMBL3084869) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1F)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24FNO/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14H2,1H3/t16-,17+,18+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125098 (1-Benzyl-4-(3-chloro-benzyl)-piperazine | CHEMBL16...) Show SMILES Clc1cccc(CN2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C18H21ClN2/c19-18-8-4-7-17(13-18)15-21-11-9-20(10-12-21)14-16-5-2-1-3-6-16/h1-8,13H,9-12,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50065140 (4-Iodo-N-(2-piperidin-1-yl-ethyl)-benzenesulfonami...) Show SMILES Ic1ccc(cc1)S(=O)(=O)NCCN1CCCCC1 Show InChI InChI=1S/C13H19IN2O2S/c14-12-4-6-13(7-5-12)19(17,18)15-8-11-16-9-2-1-3-10-16/h4-7,15H,1-3,8-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The George Washington University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranes				J Med Chem 41: 2445-50 (1998) Article DOI: 10.1021/jm9800447 BindingDB Entry DOI: 10.7270/Q27P8XHM
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125099 (1-Benzyl-4-(4-methoxy-benzyl)-piperazine | 1-benzy...) Show SMILES COc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C19H24N2O/c1-22-19-9-7-18(8-10-19)16-21-13-11-20(12-14-21)15-17-5-3-2-4-6-17/h2-10H,11-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007314 (CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...) Show SMILES Clc1ccc(CCN[C@@H]2CCCC[C@@H]2N2CCCC2)cc1Cl Show InChI InChI=1S/C18H26Cl2N2/c19-15-8-7-14(13-16(15)20)9-10-21-17-5-1-2-6-18(17)22-11-3-4-12-22/h7-8,13,17-18,21H,1-6,9-12H2/t17-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain				J Med Chem 34: 3058-65 (1991) BindingDB Entry DOI: 10.7270/Q2VX0FGB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454825 (CHEMBL3084878) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1C)N2C |TLB:9:7:24:3.2| Show InChI InChI=1S/C22H27NO/c1-16-8-6-7-11-21(16)22(17-9-4-3-5-10-17)24-20-14-18-12-13-19(15-20)23(18)2/h3-11,18-20,22H,12-15H2,1-2H3/t18-,19+,20+,22?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000065 (CHEMBL141501 | [2-(3,4-Dichloro-phenyl)-ethyl]-eth...) Show SMILES CCN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H24Cl2N2/c1-2-19(11-12-20-8-3-4-9-20)10-7-14-5-6-15(17)16(18)13-14/h5-6,13H,2-4,7-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000769 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(5-fluoro-pent...) Show SMILES FCCCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-9-22-12-10-21(11-13-22)8-3-1-2-7-20/h4-5,14H,1-3,6-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044714 (1-Butyl-4-[2-(3,4-dichloro-phenyl)-ethyl]-piperazi...) Show SMILES CCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C16H24Cl2N2/c1-2-3-7-19-9-11-20(12-10-19)8-6-14-4-5-15(17)16(18)13-14/h4-5,13H,2-3,6-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125093 (1-Benzyl-4-(3,4-dichloro-benzyl)-piperazine | CHEM...) Show SMILES Clc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1Cl Show InChI InChI=1S/C18H20Cl2N2/c19-17-7-6-16(12-18(17)20)14-22-10-8-21(9-11-22)13-15-4-2-1-3-5-15/h1-7,12H,8-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50366775 (BENZTROPINE | Benzatropine) Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50366775 (BENZTROPINE | Benzatropine) Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Muscarinic receptor from rat brain membranes using [3H]pirenzepine				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454828 (CHEMBL3084907) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1cccc(F)c1)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24FNO/c1-23-18-10-11-19(23)14-20(13-18)24-21(15-6-3-2-4-7-15)16-8-5-9-17(22)12-16/h2-9,12,18-21H,10-11,13-14H2,1H3/t18-,19+,20+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000067 (CHEMBL347514 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...) Show SMILES C[C@@H](CN1CCCC1)N(C)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H24Cl2N2/c1-13(12-20-8-3-4-9-20)19(2)10-7-14-5-6-15(17)16(18)11-14/h5-6,11,13H,3-4,7-10,12H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50065144 (CHEMBL79660 | N-(2-Azepan-1-yl-ethyl)-4-bromo-benz...) Show SMILES Brc1ccc(cc1)S(=O)(=O)NCCN1CCCCCC1 Show InChI InChI=1S/C14H21BrN2O2S/c15-13-5-7-14(8-6-13)20(18,19)16-9-12-17-10-3-1-2-4-11-17/h5-8,16H,1-4,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The George Washington University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranes				J Med Chem 41: 2445-50 (1998) Article DOI: 10.1021/jm9800447 BindingDB Entry DOI: 10.7270/Q27P8XHM
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032410 (3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...) Show SMILES CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3,9:10:1:15.13.14| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.				J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036227 ((2S,6S,11S)-3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hex...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3/t15-,20+,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity against Sigma opioid receptor type 1 using [3H]-(+)-Pentazocine in guinea pig brain membranes				J Med Chem 42: 4621-9 (1999) BindingDB Entry DOI: 10.7270/Q2T43SBK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032410 (3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...) Show SMILES CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3,9:10:1:15.13.14| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.				J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032410 (3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...) Show SMILES CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3,9:10:1:15.13.14| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligand				J Med Chem 38: 2986-9 (1995) BindingDB Entry DOI: 10.7270/Q2XK8DMX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036227 ((2S,6S,11S)-3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hex...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3/t15-,20+,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at Sigma receptor type 1, displacement of [3H]-(+)-pentazocine from guinea pig brain membranes				J Med Chem 38: 565-9 (1995) BindingDB Entry DOI: 10.7270/Q2X63M0N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The George Washington University Medical Center Curated by ChEMBL					Assay Description Inhibition Constant for 4-[125I]-IPBS binding to sigma 1 receptor in guinea pig brain membranes				J Med Chem 41: 2445-50 (1998) Article DOI: 10.1021/jm9800447 BindingDB Entry DOI: 10.7270/Q27P8XHM
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068432 (1-[2-(3-Nitro-phenyl)-ethyl]-4-(3-phenyl-propyl)-p...) Show SMILES [O-][N+](=O)c1cccc(CCN2CCN(CCCc3ccccc3)CC2)c1 Show InChI InChI=1S/C21H27N3O2/c25-24(26)21-10-4-8-20(18-21)11-13-23-16-14-22(15-17-23)12-5-9-19-6-2-1-3-7-19/h1-4,6-8,10,18H,5,9,11-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000070 (CHEMBL143178 | N-[2-(3,4-Dichloro-phenyl)-ethyl]-N...) Show SMILES CCN(CC)CCN(C)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H24Cl2N2/c1-4-19(5-2)11-10-18(3)9-8-13-6-7-14(16)15(17)12-13/h6-7,12H,4-5,8-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000080 (CHEMBL422834 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...) Show SMILES C[C@H](CN1CCCC1)N(C)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H24Cl2N2/c1-13(12-20-8-3-4-9-20)19(2)10-7-14-5-6-15(17)16(18)11-14/h5-6,11,13H,3-4,7-10,12H2,1-2H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000074 (CHEMBL142596 | [2-(3-Chloro-phenyl)-ethyl]-methyl-...) Show SMILES CN(CCN1CCCC1)CCc1cccc(Cl)c1 Show InChI InChI=1S/C15H23ClN2/c1-17(11-12-18-8-2-3-9-18)10-7-14-5-4-6-15(16)13-14/h4-6,13H,2-3,7-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454824 (CHEMBL3084909) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1cccc(F)c1)c1cccc(F)c1)N2C |TLB:9:7:25:2.3| Show InChI InChI=1S/C21H23F2NO/c1-24-18-8-9-19(24)13-20(12-18)25-21(14-4-2-6-16(22)10-14)15-5-3-7-17(23)11-15/h2-7,10-11,18-21H,8-9,12-13H2,1H3/t18-,19+,20+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000769 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(5-fluoro-pent...) Show SMILES FCCCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-9-22-12-10-21(11-13-22)8-3-1-2-7-20/h4-5,14H,1-3,6-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000780 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	0.890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Digestive Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards kappa opioid receptor using [3H](-)-U-69,593 in guinea pig ileum				J Med Chem 32: 1996-2002 (1989) BindingDB Entry DOI: 10.7270/Q2ZG6STP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50082625 ((2R,6R,11R)-3-Benzyl-11-methyl-1,2,3,4,5,6-hexahyd...) Show SMILES C[C@H]1[C@H]2Cc3ccccc3[C@@H]1CCN2Cc1ccccc1 |TLB:14:13:1:9.3.4| Show InChI InChI=1S/C20H23N/c1-15-18-11-12-21(14-16-7-3-2-4-8-16)20(15)13-17-9-5-6-10-19(17)18/h2-10,15,18,20H,11-14H2,1H3/t15-,18-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity against Sigma opioid receptor type 1 using [3H]-(+)-Pentazocine in guinea pig brain membranes				J Med Chem 42: 4621-9 (1999) BindingDB Entry DOI: 10.7270/Q2T43SBK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036229 ((2S,6S,11S)-3-(4-Fluoro-benzyl)-6,11-dimethyl-1,2,...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(F)cc1 |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C21H24FNO/c1-14-20-11-16-5-8-18(24)12-19(16)21(14,2)9-10-23(20)13-15-3-6-17(22)7-4-15/h3-8,12,14,20,24H,9-11,13H2,1-2H3/t14-,20+,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at Sigma receptor type 1, displacement of [3H]-(+)-pentazocine from guinea pig brain membranes				J Med Chem 38: 565-9 (1995) BindingDB Entry DOI: 10.7270/Q2X63M0N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044713 (2-[2-(3,4-Dichloro-phenyl)-ethyl]-octahydro-pyrido...) Show SMILES Clc1ccc(CCN2CCN3CCCCC3C2)cc1Cl Show InChI InChI=1S/C16H22Cl2N2/c17-15-5-4-13(11-16(15)18)6-8-19-9-10-20-7-2-1-3-14(20)12-19/h4-5,11,14H,1-3,6-10,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454829 (CHEMBL3084870) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1cccc(Cl)c1)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24ClNO/c1-23-18-10-11-19(23)14-20(13-18)24-21(15-6-3-2-4-7-15)16-8-5-9-17(22)12-16/h2-9,12,18-21H,10-11,13-14H2,1H3/t18-,19+,20+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Oryctolagus cuniculus (Rabbit))	BDBM25400 ((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12 Show InChI InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by PDSP Ki Database									J Pharmacol Exp Ther 280: 122-8 (1997) BindingDB Entry DOI: 10.7270/Q2J67FFH
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Adenosine receptor A1 (Oryctolagus cuniculus (Rabbit))	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI InChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by PDSP Ki Database									J Pharmacol Exp Ther 280: 122-8 (1997) BindingDB Entry DOI: 10.7270/Q2J67FFH
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Oryctolagus cuniculus (Rabbit))	BDBM50006730 ((R)-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethyla...) Show SMILES CC(Cc1ccccc1)Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1O Show InChI InChI=1S/C19H23N5O4/c1-11(7-12-5-3-2-4-6-12)23-17-14-18(21-9-20-17)24(10-22-14)19-16(27)15(26)13(8-25)28-19/h2-6,9-11,13,15-16,19,25-27H,7-8H2,1H3,(H,20,21,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by PDSP Ki Database									J Pharmacol Exp Ther 280: 122-8 (1997) BindingDB Entry DOI: 10.7270/Q2J67FFH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000079 (CHEMBL142755 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...) Show SMILES Clc1ccc(CCNCCN2CCCC2)cc1Cl Show InChI InChI=1S/C14H20Cl2N2/c15-13-4-3-12(11-14(13)16)5-6-17-7-10-18-8-1-2-9-18/h3-4,11,17H,1-2,5-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair

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