Compile Data Set for Download or QSAR

Found 203 hits with Last Name = 'zimmerman' and Initial = 'mn'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220180 (CHEMBL243669 | N-[3-fluoro-4'-(trifluoromethyl)-4-...) Show SMILES NS(=O)(=O)Nc1ccc(cc1F)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H10F4N2O2S/c14-11-7-9(3-6-12(11)19-22(18,20)21)8-1-4-10(5-2-8)13(15,16)17/h1-7,19H,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220182 (CHEMBL390629 | N-[4'-(trifluoromethyl)-4-biphenyly...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H11F3N2O2S/c14-13(15,16)11-5-1-9(2-6-11)10-3-7-12(8-4-10)18-21(17,19)20/h1-8,18H,(H2,17,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220169 (CHEMBL244933 | N-[4'-(trifluoromethyl)-4-biphenyly...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H12F3NO2S/c1-21(19,20)18-13-8-4-11(5-9-13)10-2-6-12(7-3-10)14(15,16)17/h2-9,18H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220180 (CHEMBL243669 | N-[3-fluoro-4'-(trifluoromethyl)-4-...) Show SMILES NS(=O)(=O)Nc1ccc(cc1F)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H10F4N2O2S/c14-11-7-9(3-6-12(11)19-22(18,20)21)8-1-4-10(5-2-8)13(15,16)17/h1-7,19H,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181559 (1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BEN...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2ccc(F)cc12 |t:3| Show InChI InChI=1S/C21H18FN3O4S/c22-13-7-8-16-14(11-13)19(26)18(21(27)25(16)10-9-12-5-6-12)20-23-15-3-1-2-4-17(15)30(28,29)24-20/h1-4,7-8,11-12,26H,5-6,9-10H2,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181559 (1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BEN...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2ccc(F)cc12 |t:3| Show InChI InChI=1S/C21H18FN3O4S/c22-13-7-8-16-14(11-13)19(26)18(21(27)25(16)10-9-12-5-6-12)20-23-15-3-1-2-4-17(15)30(28,29)24-20/h1-4,7-8,11-12,26H,5-6,9-10H2,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b NS5B RNA polymerase				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220195 (CHEMBL243885 | N-[4'-(trifluoromethyl)-4-biphenyly...) Show SMILES NC(=S)Nc1ccc(cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H11F3N2S/c15-14(16,17)11-5-1-9(2-6-11)10-3-7-12(8-4-10)19-13(18)20/h1-8H,(H3,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181559 (1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BEN...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2ccc(F)cc12 |t:3| Show InChI InChI=1S/C21H18FN3O4S/c22-13-7-8-16-14(11-13)19(26)18(21(27)25(16)10-9-12-5-6-12)20-23-15-3-1-2-4-17(15)30(28,29)24-20/h1-4,7-8,11-12,26H,5-6,9-10H2,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV 2a NS5B RNA polymerase				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181650 (1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydro-1-...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2ccccc12 |t:3| Show InChI InChI=1S/C21H19N3O4S/c25-19-14-5-1-3-7-16(14)24(12-11-13-9-10-13)21(26)18(19)20-22-15-6-2-4-8-17(15)29(27,28)23-20/h1-8,13,25H,9-12H2,(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220159 (CHEMBL389589 | N-[3'-fluoro-4'-(trifluoromethyl)-1...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C13H10F4N2O2S/c14-12-7-9(3-6-11(12)13(15,16)17)8-1-4-10(5-2-8)19-22(18,20)21/h1-7,19H,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220185 (1-(3-fluoro-4'-(trifluoromethyl)biphenyl-4-yl)urea...) Show SMILES NC(=O)Nc1ccc(cc1F)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H10F4N2O/c15-11-7-9(3-6-12(11)20-13(19)21)8-1-4-10(5-2-8)14(16,17)18/h1-7H,(H3,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220182 (CHEMBL390629 | N-[4'-(trifluoromethyl)-4-biphenyly...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H11F3N2O2S/c14-13(15,16)11-5-1-9(2-6-11)10-3-7-12(8-4-10)18-21(17,19)20/h1-8,18H,(H2,17,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181560 (3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]th...) Show SMILES CC(C)CCn1c2ccc(F)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C21H20FN3O4S/c1-12(2)9-10-25-16-8-7-13(22)11-14(16)19(26)18(21(25)27)20-23-15-5-3-4-6-17(15)30(28,29)24-20/h3-8,11-12,26H,9-10H2,1-2H3,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181569 (CHEMBL425221 | [3-(1,1-dioxo-1,4-dihydrobenzo[1,2,...) Show SMILES CC(C)CCn1c2ccc(NCC(O)=O)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:21| Show InChI InChI=1S/C23H24N4O6S/c1-13(2)9-10-27-17-8-7-14(24-12-19(28)29)11-15(17)21(30)20(23(27)31)22-25-16-5-3-4-6-18(16)34(32,33)26-22/h3-8,11,13,24,30H,9-10,12H2,1-2H3,(H,25,26)(H,28,29)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181589 (1-(3,3-dimethylbutyl)-3-(1,1-dioxo-1,4-dihydrobenz...) Show SMILES CC(C)(C)CCn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C22H23N3O4S/c1-22(2,3)12-13-25-16-10-6-4-8-14(16)19(26)18(21(25)27)20-23-15-9-5-7-11-17(15)30(28,29)24-20/h4-11,26H,12-13H2,1-3H3,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181588 (3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES COc1ccc2n(CCC(C)C)c(=O)c(C3=Nc4ccccc4S(=O)(=O)N3)c(O)c2c1 |t:15| Show InChI InChI=1S/C22H23N3O5S/c1-13(2)10-11-25-17-9-8-14(30-3)12-15(17)20(26)19(22(25)27)21-23-16-6-4-5-7-18(16)31(28,29)24-21/h4-9,12-13,26H,10-11H2,1-3H3,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181584 (4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-...) Show SMILES CC(C)CCn1c2ccc(OCC(N)=O)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:21| Show InChI InChI=1S/C23H24N4O6S/c1-13(2)9-10-27-17-8-7-14(33-12-19(24)28)11-15(17)21(29)20(23(27)30)22-25-16-5-3-4-6-18(16)34(31,32)26-22/h3-8,11,13,29H,9-10,12H2,1-2H3,(H2,24,28)(H,25,26)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220201 (CHEMBL243431 | N-[3-amino-4'-(trifluoromethyl)-4-b...) Show SMILES Nc1cc(ccc1NS(N)(=O)=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H12F3N3O2S/c14-13(15,16)10-4-1-8(2-5-10)9-3-6-12(11(17)7-9)19-22(18,20)21/h1-7,19H,17H2,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181583 (3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(Cc2ccoc2)c2ccccc12 |t:3| Show InChI InChI=1S/C21H15N3O5S/c25-19-14-5-1-3-7-16(14)24(11-13-9-10-29-12-13)21(26)18(19)20-22-15-6-2-4-8-17(15)30(27,28)23-20/h1-10,12,25H,11H2,(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220155 (CHEMBL244697 | N-[3'-nitro-4'-(trifluoromethyl)-4-...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(c1)[N+]([O-])=O)C(F)(F)F Show InChI InChI=1S/C13H10F3N3O4S/c14-13(15,16)11-6-3-9(7-12(11)19(20)21)8-1-4-10(5-2-8)18-24(17,22)23/h1-7,18H,(H2,17,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220176 (CHEMBL242181 | N-[4-(2,2-difluoro-1,3-benzodioxol-...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc2OC(F)(F)Oc2c1 Show InChI InChI=1S/C13H10F2N2O4S/c14-13(15)20-11-6-3-9(7-12(11)21-13)8-1-4-10(5-2-8)17-22(16,18)19/h1-7,17H,(H2,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM30406 (CHEMBL176058 | benzo[1,2,4]thiadiazine-1,1-dioxide...) Show SMILES CC(C)CCn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C21H21N3O4S/c1-13(2)11-12-24-16-9-5-3-7-14(16)19(25)18(21(24)26)20-22-15-8-4-6-10-17(15)29(27,28)23-20/h3-10,13,25H,11-12H2,1-2H3,(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181634 (6-Amino-1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-di...) Show SMILES Nc1ccc2n(CCC3CC3)c(=O)c(C3=Nc4ccccc4S(=O)(=O)N3)c(O)c2c1 |t:15| Show InChI InChI=1S/C21H20N4O4S/c22-13-7-8-16-14(11-13)19(26)18(21(27)25(16)10-9-12-5-6-12)20-23-15-3-1-2-4-17(15)30(28,29)24-20/h1-4,7-8,11-12,26H,5-6,9-10,22H2,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181570 (5-chloro-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiad...) Show SMILES CC(C)CCn1c2cccc(Cl)c2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C21H20ClN3O4S/c1-12(2)10-11-25-15-8-5-6-13(22)17(15)19(26)18(21(25)27)20-23-14-7-3-4-9-16(14)30(28,29)24-20/h3-9,12,26H,10-11H2,1-2H3,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181567 (4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-...) Show SMILES CC(C)CCn1c2ccc(OCC#N)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:20| Show InChI InChI=1S/C23H22N4O5S/c1-14(2)9-11-27-18-8-7-15(32-12-10-24)13-16(18)21(28)20(23(27)29)22-25-17-5-3-4-6-19(17)33(30,31)26-22/h3-8,13-14,28H,9,11-12H2,1-2H3,(H,25,26)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181646 (1-(3-bromobenzyl)-3-(1,1-dioxo-1,4-dihydrobenzo[1,...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(Cc2cccc(Br)c2)c2ccccc12 |t:3| Show InChI InChI=1S/C23H16BrN3O4S/c24-15-7-5-6-14(12-15)13-27-18-10-3-1-8-16(18)21(28)20(23(27)29)22-25-17-9-2-4-11-19(17)32(30,31)26-22/h1-12,28H,13H2,(H,25,26)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220162 (CHEMBL243883 | N-[4'-(trifluoromethyl)-4-biphenyly...) Show SMILES NC(=O)Nc1ccc(cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H11F3N2O/c15-14(16,17)11-5-1-9(2-6-11)10-3-7-12(8-4-10)19-13(18)20/h1-8H,(H3,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181666 (3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]thiadiazin-...) Show SMILES CC1CC1Cn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C21H19N3O4S/c1-12-10-13(12)11-24-16-8-4-2-6-14(16)19(25)18(21(24)26)20-22-15-7-3-5-9-17(15)29(27,28)23-20/h2-9,12-13,25H,10-11H2,1H3,(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181579 (6-chloro-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiad...) Show SMILES CC(C)CCn1c2ccc(Cl)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C21H20ClN3O4S/c1-12(2)9-10-25-16-8-7-13(22)11-14(16)19(26)18(21(25)27)20-23-15-5-3-4-6-17(15)30(28,29)24-20/h3-8,11-12,26H,9-10H2,1-2H3,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181615 (3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES CC(CCn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O)C(F)(F)F |t:15| Show InChI InChI=1S/C21H18F3N3O4S/c1-12(21(22,23)24)10-11-27-15-8-4-2-6-13(15)18(28)17(20(27)29)19-25-14-7-3-5-9-16(14)32(30,31)26-19/h2-9,12,28H,10-11H2,1H3,(H,25,26)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181601 (3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES CC(C)CCn1c2ccc(C)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C22H23N3O4S/c1-13(2)10-11-25-17-9-8-14(3)12-15(17)20(26)19(22(25)27)21-23-16-6-4-5-7-18(16)30(28,29)24-21/h4-9,12-13,26H,10-11H2,1-3H3,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181623 (3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES CC(C)CCn1c2cccc(O)c2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C21H21N3O5S/c1-12(2)10-11-24-14-7-5-8-15(25)17(14)19(26)18(21(24)27)20-22-13-6-3-4-9-16(13)30(28,29)23-20/h3-9,12,25-26H,10-11H2,1-2H3,(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181580 (1-(3,3-dimethylbutyl)-3-(1,1-dioxo-1,4-dihydrobenz...) Show SMILES CC(C)(C)CCn1c2ccc(NCCO)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:21| Show InChI InChI=1S/C24H28N4O5S/c1-24(2,3)10-12-28-18-9-8-15(25-11-13-29)14-16(18)21(30)20(23(28)31)22-26-17-6-4-5-7-19(17)34(32,33)27-22/h4-9,14,25,29-30H,10-13H2,1-3H3,(H,26,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181559 (1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BEN...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2ccc(F)cc12 |t:3| Show InChI InChI=1S/C21H18FN3O4S/c22-13-7-8-16-14(11-13)19(26)18(21(27)25(16)10-9-12-5-6-12)20-23-15-3-1-2-4-17(15)30(28,29)24-20/h1-4,7-8,11-12,26H,5-6,9-10H2,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1a NS5B RNA polymerase				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181624 (1-cyclobutylmethyl-3-(1,1-dioxo-1,2-dihydrobenzo[1...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CC2CCC2)c2ccccc12 |t:3| Show InChI InChI=1S/C21H19N3O4S/c25-19-14-8-1-3-10-16(14)24(12-13-6-5-7-13)21(26)18(19)20-22-15-9-2-4-11-17(15)29(27,28)23-20/h1-4,8-11,13,25H,5-7,12H2,(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181596 (3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES CSCCn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:15| Show InChI InChI=1S/C19H17N3O4S2/c1-27-11-10-22-14-8-4-2-6-12(14)17(23)16(19(22)24)18-20-13-7-3-5-9-15(13)28(25,26)21-18/h2-9,23H,10-11H2,1H3,(H,20,21)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220188 (CHEMBL244126 | N-(4'-t-butyl-4-biphenylyl)urea) Show SMILES CC(C)(C)c1ccc(cc1)-c1ccc(NC(N)=O)cc1 Show InChI InChI=1S/C17H20N2O/c1-17(2,3)14-8-4-12(5-9-14)13-6-10-15(11-7-13)19-16(18)20/h4-11H,1-3H3,(H3,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220192 (CHEMBL397249 | N-(4'-isopropyl-4-biphenylyl)urea) Show SMILES CC(C)c1ccc(cc1)-c1ccc(NC(N)=O)cc1 Show InChI InChI=1S/C16H18N2O/c1-11(2)12-3-5-13(6-4-12)14-7-9-15(10-8-14)18-16(17)19/h3-11H,1-2H3,(H3,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220177 (CHEMBL389588 | N-{4'-[(trifluoromethyl)sulfonyl]-4...) Show SMILES NC(=O)Nc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)C(F)(F)F Show InChI InChI=1S/C14H11F3N2O3S/c15-14(16,17)23(21,22)12-7-3-10(4-8-12)9-1-5-11(6-2-9)19-13(18)20/h1-8H,(H3,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181598 (3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(Cc2ccncc2)c2ccccc12 |t:3| Show InChI InChI=1S/C22H16N4O4S/c27-20-15-5-1-3-7-17(15)26(13-14-9-11-23-12-10-14)22(28)19(20)21-24-16-6-2-4-8-18(16)31(29,30)25-21/h1-12,27H,13H2,(H,24,25)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181593 (6-amino-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadi...) Show SMILES CC(C)CCn1c2ccc(N)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C21H22N4O4S/c1-12(2)9-10-25-16-8-7-13(22)11-14(16)19(26)18(21(25)27)20-23-15-5-3-4-6-17(15)30(28,29)24-20/h3-8,11-12,26H,9-10,22H2,1-2H3,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220172 (4'-(trifluoromethyl)-4-biphenylyl sulfamate | CHEM...) Show SMILES NS(=O)(=O)Oc1ccc(cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H10F3NO3S/c14-13(15,16)11-5-1-9(2-6-11)10-3-7-12(8-4-10)20-21(17,18)19/h1-8H,(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181631 (3-(1,1-Dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES CCC(C)CCn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:17| Show InChI InChI=1S/C22H23N3O4S/c1-3-14(2)12-13-25-17-10-6-4-8-15(17)20(26)19(22(25)27)21-23-16-9-5-7-11-18(16)30(28,29)24-21/h4-11,14,26H,3,12-13H2,1-2H3,(H,23,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220209 (CHEMBL242780 | N-[3-(methoxy)-4'-(trifluoromethyl)...) Show SMILES COc1cc(ccc1NS(N)(=O)=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H13F3N2O3S/c1-22-13-8-10(4-7-12(13)19-23(18,20)21)9-2-5-11(6-3-9)14(15,16)17/h2-8,19H,1H3,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220170 (CHEMBL243649 | N-[3-Chloro-4'-(trifluoromethyl)-4-...) Show SMILES NS(=O)(=O)Nc1ccc(cc1Cl)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H10ClF3N2O2S/c14-11-7-9(3-6-12(11)19-22(18,20)21)8-1-4-10(5-2-8)13(15,16)17/h1-7,19H,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50220181 (CHEMBL397673 | N-[4-(2,2,3,3-tetrafluoro-2,3-dihyd...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc2OC(F)(F)C(F)(F)Oc2c1 Show InChI InChI=1S/C14H10F4N2O4S/c15-13(16)14(17,18)24-12-7-9(3-6-11(12)23-13)8-1-4-10(5-2-8)20-25(19,21)22/h1-7,20H,(H2,19,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181660 (3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CC2CC2)c2ccccc12 |t:3| Show InChI InChI=1S/C20H17N3O4S/c24-18-13-5-1-3-7-15(13)23(11-12-9-10-12)20(25)17(18)19-21-14-6-2-4-8-16(14)28(26,27)22-19/h1-8,12,24H,9-11H2,(H,21,22)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181578 (3-(1,1-dioxo-1,4-dihydro-benzo[1,2,4]thiadiazin-3-...) Show SMILES CCCCCn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:16| Show InChI InChI=1S/C21H21N3O4S/c1-2-3-8-13-24-16-11-6-4-9-14(16)19(25)18(21(24)26)20-22-15-10-5-7-12-17(15)29(27,28)23-20/h4-7,9-12,25H,2-3,8,13H2,1H3,(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181653 (3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]thiadiazin-...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(Cc2cccc(c2)[N+]([O-])=O)c2ccccc12 |t:3| Show InChI InChI=1S/C23H16N4O6S/c28-21-16-8-1-3-10-18(16)26(13-14-6-5-7-15(12-14)27(30)31)23(29)20(21)22-24-17-9-2-4-11-19(17)34(32,33)25-22/h1-12,28H,13H2,(H,24,25)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181605 (1-benzyl-3-(1,1-dioxo-1,2-dihydro-benzo[1,2,4]thia...) Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(Cc2ccccc2)c2ccccc12 |t:3| Show InChI InChI=1S/C23H17N3O4S/c27-21-16-10-4-6-12-18(16)26(14-15-8-2-1-3-9-15)23(28)20(21)22-24-17-11-5-7-13-19(17)31(29,30)25-22/h1-13,27H,14H2,(H,24,25)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair

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