Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with all data for entry = 2573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372167 (6-(2-chloro- phenyl)-N- (3-morpholino- phenyl)- 5H...) Show SMILES Clc1ccccc1-c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C22H20ClN5O/c23-18-7-2-1-6-17(18)19-13-20-21(26-19)14-24-22(27-20)25-15-4-3-5-16(12-15)28-8-10-29-11-9-28/h1-7,12-14,26H,8-11H2,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372149 (N-(4-((1- methylpiperidin-4- yl)oxy)phenyl)-6- (o-...) Show SMILES CN1CCC(CC1)Oc1ccc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2C)cc1 Show InChI InChI=1S/C25H27N5O/c1-17-5-3-4-6-21(17)22-15-23-24(28-22)16-26-25(29-23)27-18-7-9-19(10-8-18)31-20-11-13-30(2)14-12-20/h3-10,15-16,20,28H,11-14H2,1-2H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372150 (N-(3- morpholnophenyl)- 6-(o-tolyl)-5H- pyrrolo[3,...) Show SMILES Cc1ccccc1-c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C23H23N5O/c1-16-5-2-3-8-19(16)20-14-21-22(26-20)15-24-23(27-21)25-17-6-4-7-18(13-17)28-9-11-29-12-10-28/h2-8,13-15,26H,9-12H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372151 (N-(3-(4- methylpiperazin-1- yl)phenyl)- 6-(o-tolyl...) Show SMILES CN1CCN(CC1)c1cccc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2C)c1 Show InChI InChI=1S/C24H26N6/c1-17-6-3-4-9-20(17)21-15-22-23(27-21)16-25-24(28-22)26-18-7-5-8-19(14-18)30-12-10-29(2)11-13-30/h3-9,14-16,27H,10-13H2,1-2H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372165 (N-(4-((4- methylpiperazin-1- yl)methyl)phenyl)- 6-...) Show SMILES CN1CCN(Cc2ccc(Nc3ncc4[nH]c(cc4n3)-c3ccccc3C)cc2)CC1 Show InChI InChI=1S/C25H28N6/c1-18-5-3-4-6-21(18)22-15-23-24(28-22)16-26-25(29-23)27-20-9-7-19(8-10-20)17-31-13-11-30(2)12-14-31/h3-10,15-16,28H,11-14,17H2,1-2H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372153 (6-(2,6- dimethylphenyl)- N-(3-(4- methylpiperazin-...) Show SMILES CN1CCN(CC1)c1cccc(Nc2ncc3[nH]c(cc3n2)-c2c(C)cccc2C)c1 Show InChI InChI=1S/C25H28N6/c1-17-6-4-7-18(2)24(17)22-15-21-23(28-22)16-26-25(29-21)27-19-8-5-9-20(14-19)31-12-10-30(3)11-13-31/h4-9,14-16,28H,10-13H2,1-3H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372162 (N-(4- (morpholino- methyl) phenyl)-6-(o-tolyl)- 5H...) Show SMILES Cc1ccccc1-c1cc2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2[nH]1 Show InChI InChI=1S/C24H25N5O/c1-17-4-2-3-5-20(17)21-14-22-23(27-21)15-25-24(28-22)26-19-8-6-18(7-9-19)16-29-10-12-30-13-11-29/h2-9,14-15,27H,10-13,16H2,1H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372155 (N-(4- morpholino- phenyl)-6- (o-tolyl)-5H- pyrrolo...) Show SMILES Cc1ccccc1-c1cc2nc(Nc3ccc(cc3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C23H23N5O/c1-16-4-2-3-5-19(16)20-14-21-22(26-20)15-24-23(27-21)25-17-6-8-18(9-7-17)28-10-12-29-13-11-28/h2-9,14-15,26H,10-13H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372156 (N-(3-((4- methylpiperazin-1- yl)methyl)phenyl)- 6-...) Show SMILES CN1CCN(Cc2cccc(Nc3ncc4[nH]c(cc4n3)-c3ccccc3C)c2)CC1 Show InChI InChI=1S/C25H28N6/c1-18-6-3-4-9-21(18)22-15-23-24(28-22)16-26-25(29-23)27-20-8-5-7-19(14-20)17-31-12-10-30(2)11-13-31/h3-9,14-16,28H,10-13,17H2,1-2H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372164 (N-(4-(4- methylpiperazin-1- yl)phenyl)-6- (o-tolyl...) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2C)cc1 Show InChI InChI=1S/C24H26N6/c1-17-5-3-4-6-20(17)21-15-22-23(27-21)16-25-24(28-22)26-18-7-9-19(10-8-18)30-13-11-29(2)12-14-30/h3-10,15-16,27H,11-14H2,1-2H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372158 (N-(3-(4- methylpiperazin-1- yl)phenyl)-6- (thiophe...) Show SMILES CN1CCN(CC1)c1cccc(Nc2ncc3[nH]c(cc3n2)-c2ccsc2)c1 Show InChI InChI=1S/C21H22N6S/c1-26-6-8-27(9-7-26)17-4-2-3-16(11-17)23-21-22-13-20-19(25-21)12-18(24-20)15-5-10-28-14-15/h2-5,10-14,24H,6-9H2,1H3,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372159 (6-(2,6- dimethylphenyl)- N-(3- morpholinophenyl)- ...) Show SMILES Cc1cccc(C)c1-c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C24H25N5O/c1-16-5-3-6-17(2)23(16)21-14-20-22(27-21)15-25-24(28-20)26-18-7-4-8-19(13-18)29-9-11-30-12-10-29/h3-8,13-15,27H,9-12H2,1-2H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372163 (2-(4-(3-((6-(2- chlorophenyl)-5H- pyrrolo[3,2- d]p...) Show SMILES OCCN1CCN(CC1)c1cccc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2Cl)c1 Show InChI InChI=1S/C24H25ClN6O/c25-20-7-2-1-6-19(20)21-15-22-23(28-21)16-26-24(29-22)27-17-4-3-5-18(14-17)31-10-8-30(9-11-31)12-13-32/h1-7,14-16,28,32H,8-13H2,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372154 (N-(3- (morpholino- methyl)phenyl)- 6-(o-tolyl)- 5H...) Show SMILES Cc1ccccc1-c1cc2nc(Nc3cccc(CN4CCOCC4)c3)ncc2[nH]1 Show InChI InChI=1S/C24H25N5O/c1-17-5-2-3-8-20(17)21-14-22-23(27-21)15-25-24(28-22)26-19-7-4-6-18(13-19)16-29-9-11-30-12-10-29/h2-8,13-15,27H,9-12,16H2,1H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372160 (6-(2-fluorophenyl)- N-(3-morpholino- phenyl)- 5H-p...) Show SMILES Fc1ccccc1-c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C22H20FN5O/c23-18-7-2-1-6-17(18)19-13-20-21(26-19)14-24-22(27-20)25-15-4-3-5-16(12-15)28-8-10-29-11-9-28/h1-7,12-14,26H,8-11H2,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372172 (6-(2-methoxy- phenyl)- N-(3- morpholino- phenyl)- ...) Show SMILES COc1ccccc1-c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C23H23N5O2/c1-29-22-8-3-2-7-18(22)19-14-20-21(26-19)15-24-23(27-20)25-16-5-4-6-17(13-16)28-9-11-30-12-10-28/h2-8,13-15,26H,9-12H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372171 (N-((tetrahydro- 2H-pyran-4-yl) methyl)-6- (o-tolyl...) Show SMILES Cc1ccccc1-c1cc2nc(NCC3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C19H22N4O/c1-13-4-2-3-5-15(13)16-10-17-18(22-16)12-21-19(23-17)20-11-14-6-8-24-9-7-14/h2-5,10,12,14,22H,6-9,11H2,1H3,(H,20,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372168 ((1r,4)-4-((6- (o-tolyl)- 5H-pyrrolo[3,2- d]pyrimid...) Show SMILES Cc1ccccc1-c1cc2nc(N[C@@H]3CC[C@H](O)CC3)ncc2[nH]1 |r,wU:13.13,16.17,(5.08,-2.1,;5.85,-.77,;7.39,-.77,;8.16,.56,;7.39,1.9,;5.85,1.9,;5.08,.56,;3.54,.56,;2.64,-.68,;1.17,-.21,;-.16,-.98,;-1.49,-.21,;-2.83,-.98,;-4.16,-.21,;-4.16,1.33,;-5.5,2.1,;-6.83,1.33,;-8.16,2.1,;-6.83,-.21,;-5.5,-.98,;-1.49,1.33,;-.16,2.1,;1.17,1.33,;2.64,1.81,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372166 (N-(3- morpholinopropyl)- 6-(o-tolyl)-5H- pyrrolo[3...) Show SMILES Cc1ccccc1-c1cc2nc(NCCCN3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C20H25N5O/c1-15-5-2-3-6-16(15)17-13-18-19(23-17)14-22-20(24-18)21-7-4-8-25-9-11-26-12-10-25/h2-3,5-6,13-14,23H,4,7-12H2,1H3,(H,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372148 (N,6-diphenyl-5H- pyrrolo[3,2- d]pyrimidin-2-amine ...) Show SMILES N(c1ccccc1)c1ncc2[nH]c(cc2n1)-c1ccccc1 Show InChI InChI=1S/C18H14N4/c1-3-7-13(8-4-1)15-11-16-17(21-15)12-19-18(22-16)20-14-9-5-2-6-10-14/h1-12,21H,(H,19,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372170 (N-(tetrahydro-2H- pyran-4-yl)-6-(o- tolyl)-5H- pyr...) Show SMILES Cc1ccccc1-c1cc2nc(NC3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C18H20N4O/c1-12-4-2-3-5-14(12)15-10-16-17(21-15)11-19-18(22-16)20-13-6-8-23-9-7-13/h2-5,10-11,13,21H,6-9H2,1H3,(H,19,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372168 ((1r,4)-4-((6- (o-tolyl)- 5H-pyrrolo[3,2- d]pyrimid...) Show SMILES Cc1ccccc1-c1cc2nc(N[C@@H]3CC[C@H](O)CC3)ncc2[nH]1 |r,wU:13.13,16.17,(5.08,-2.1,;5.85,-.77,;7.39,-.77,;8.16,.56,;7.39,1.9,;5.85,1.9,;5.08,.56,;3.54,.56,;2.64,-.68,;1.17,-.21,;-.16,-.98,;-1.49,-.21,;-2.83,-.98,;-4.16,-.21,;-4.16,1.33,;-5.5,2.1,;-6.83,1.33,;-8.16,2.1,;-6.83,-.21,;-5.5,-.98,;-1.49,1.33,;-.16,2.1,;1.17,1.33,;2.64,1.81,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372152 (2-(4-(2-methyl- 6-((6- (o-tolyl)-5H- pyrrolo[3,2- ...) Show SMILES Cc1nc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2C)cc(n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C24H28N8O/c1-16-5-3-4-6-18(16)19-13-20-21(28-19)15-25-24(29-20)30-22-14-23(27-17(2)26-22)32-9-7-31(8-10-32)11-12-33/h3-6,13-15,28,33H,7-12H2,1-2H3,(H,25,26,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372157 (6-cyclopentyl- N-(3-(4- methylpiperazin-1- yl)phen...) Show SMILES CN1CCN(CC1)c1cccc(Nc2ncc3[nH]c(cc3n2)C2CCCC2)c1 Show InChI InChI=1S/C22H28N6/c1-27-9-11-28(12-10-27)18-8-4-7-17(13-18)24-22-23-15-21-20(26-22)14-19(25-21)16-5-2-3-6-16/h4,7-8,13-16,25H,2-3,5-6,9-12H2,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372173 (N-((1- morpholino- cyclopentyl) methyl)-6- (o-toly...) Show SMILES Cc1ccccc1-c1cc2nc(NCC3(CCCC3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C23H29N5O/c1-17-6-2-3-7-18(17)19-14-20-21(26-19)15-24-22(27-20)25-16-23(8-4-5-9-23)28-10-12-29-13-11-28/h2-3,6-7,14-15,26H,4-5,8-13,16H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372161 (N-(3- morpholino- phenyl)-6- (tetrahydro-2H- pyran...) Show SMILES C1CC(CCO1)c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C21H25N5O2/c1-2-16(12-17(3-1)26-6-10-28-11-7-26)23-21-22-14-20-19(25-21)13-18(24-20)15-4-8-27-9-5-15/h1-3,12-15,24H,4-11H2,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair