BindingDB logo
myBDB logout

PubMed code 25007344

Compile data set for download or QSAR
Found 73 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pyruvate kinase


(Staphylococcus aureus (strain MRSA252))
BDBM50192869
PNG
(CIS-3,4-DIHYDROHAMACANTHIN B)
Show SMILES Brc1ccc2c(c[nH]c2c1)[C@@H]1CNC(=O)[C@@H](N1)c1c[nH]c2cc(Br)ccc12 |r|
Show InChI InChI=1/C20H16Br2N4O/c21-10-1-3-12-14(7-23-16(12)5-10)18-9-25-20(27)19(26-18)15-8-24-17-6-11(22)2-4-13(15)17/h1-8,18-19,23-24,26H,9H2,(H,25,27)/t18-,19-/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

Patents

PDB
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus pyruvate kinase by coupled lactate dehydrogenase continuous assay


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192877
PNG
(CHEMBL3358999)
Show SMILES COc1cc(ccc1O)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H20N2O6/c1-25-15-7-11(5-6-14(15)23)13-10-21-20(24)18(22-13)12-8-16(26-2)19(28-4)17(9-12)27-3/h5-10,23H,1-4H3,(H,21,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192871
PNG
(CHEMBL3358996)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C19H18N2O5/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)20-10-14(21-17)11-4-6-13(22)7-5-11/h4-10,22H,1-3H3,(H,20,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50192877
PNG
(CHEMBL3358999)
Show SMILES COc1cc(ccc1O)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H20N2O6/c1-25-15-7-11(5-6-14(15)23)13-10-21-20(24)18(22-13)12-8-16(26-2)19(28-4)17(9-12)27-3/h5-10,23H,1-4H3,(H,21,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50192877
PNG
(CHEMBL3358999)
Show SMILES COc1cc(ccc1O)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H20N2O6/c1-25-15-7-11(5-6-14(15)23)13-10-21-20(24)18(22-13)12-8-16(26-2)19(28-4)17(9-12)27-3/h5-10,23H,1-4H3,(H,21,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human c-KiT


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192878
PNG
(CHEMBL3358977)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C21H19N3O5/c1-27-17-6-11(7-18(28-2)20(17)29-3)19-21(26)23-10-16(24-19)14-9-22-15-5-4-12(25)8-13(14)15/h4-10,22,25H,1-3H3,(H,23,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50192871
PNG
(CHEMBL3358996)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C19H18N2O5/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)20-10-14(21-17)11-4-6-13(22)7-5-11/h4-10,22H,1-3H3,(H,20,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human c-KiT


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192850
PNG
(CHEMBL3358994)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccc(Cl)c1
Show InChI InChI=1S/C19H17ClN2O4/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)21-10-14(22-17)11-5-4-6-13(20)7-11/h4-10H,1-3H3,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 800n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 900n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human c-KiT


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192870
PNG
(CHEMBL3358985)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccc2ccccc12
Show InChI InChI=1S/C23H20N2O4/c1-27-19-11-15(12-20(28-2)22(19)29-3)21-23(26)24-13-18(25-21)17-10-6-8-14-7-4-5-9-16(14)17/h4-13H,1-3H3,(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192859
PNG
(CHEMBL3358988)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccsc1
Show InChI InChI=1S/C17H16N2O4S/c1-21-13-6-11(7-14(22-2)16(13)23-3)15-17(20)18-8-12(19-15)10-4-5-24-9-10/h4-9H,1-3H3,(H,18,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192876
PNG
(CHEMBL3358978)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccc(C)cc12
Show InChI InChI=1S/C22H21N3O4/c1-12-5-6-16-14(7-12)15(10-23-16)17-11-24-22(26)20(25-17)13-8-18(27-2)21(29-4)19(9-13)28-3/h5-11,23H,1-4H3,(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50192878
PNG
(CHEMBL3358977)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C21H19N3O5/c1-27-17-6-11(7-18(28-2)20(17)29-3)19-21(26)23-10-16(24-19)14-9-22-15-5-4-12(25)8-13(14)15/h4-10,22,25H,1-3H3,(H,23,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192846
PNG
(CHEMBL3358992)
Show SMILES COc1cccc(c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H20N2O5/c1-24-14-7-5-6-12(8-14)15-11-21-20(23)18(22-15)13-9-16(25-2)19(27-4)17(10-13)26-3/h5-11H,1-4H3,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192857
PNG
(CHEMBL3358967)
Show SMILES COc1ccc(cc1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H17N3O3/c1-25-17-8-7-12(9-18(17)26-2)19-20(24)22-11-16(23-19)14-10-21-15-6-4-3-5-13(14)15/h3-11,21H,1-2H3,(H,22,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192860
PNG
(CHEMBL1986478)
Show SMILES O=c1[nH]cc(nc1-c1c[nH]c2ccccc12)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H14N4O/c25-20-19(15-10-22-17-8-4-2-6-13(15)17)24-18(11-23-20)14-9-21-16-7-3-1-5-12(14)16/h1-11,21-22H,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192854
PNG
(CHEMBL3358987)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccoc1
Show InChI InChI=1S/C17H16N2O5/c1-21-13-6-11(7-14(22-2)16(13)23-3)15-17(20)18-8-12(19-15)10-4-5-24-9-10/h4-9H,1-3H3,(H,18,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192866
PNG
(CHEMBL3358981)
Show SMILES COc1ccc2c(c[nH]c2c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C22H21N3O5/c1-27-13-5-6-14-15(10-23-16(14)9-13)17-11-24-22(26)20(25-17)12-7-18(28-2)21(30-4)19(8-12)29-3/h5-11,23H,1-4H3,(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192856
PNG
(CHEMBL3358989)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccnc1
Show InChI InChI=1S/C18H17N3O4/c1-23-14-7-12(8-15(24-2)17(14)25-3)16-18(22)20-10-13(21-16)11-5-4-6-19-9-11/h4-10H,1-3H3,(H,20,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192874
PNG
(CHEMBL3358997)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccccc1O
Show InChI InChI=1S/C19H18N2O5/c1-24-15-8-11(9-16(25-2)18(15)26-3)17-19(23)20-10-13(21-17)12-6-4-5-7-14(12)22/h4-10,22H,1-3H3,(H,20,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50192871
PNG
(CHEMBL3358996)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccc(O)cc1
Show InChI InChI=1S/C19H18N2O5/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)20-10-14(21-17)11-4-6-13(22)7-5-11/h4-10,22H,1-3H3,(H,20,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50192850
PNG
(CHEMBL3358994)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccc(Cl)c1
Show InChI InChI=1S/C19H17ClN2O4/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)21-10-14(22-17)11-5-4-6-13(20)7-11/h4-10H,1-3H3,(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human c-KiT


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50192878
PNG
(CHEMBL3358977)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C21H19N3O5/c1-27-17-6-11(7-18(28-2)20(17)29-3)19-21(26)23-10-16(24-19)14-9-22-15-5-4-12(25)8-13(14)15/h4-10,22,25H,1-3H3,(H,23,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human c-KiT


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192868
PNG
(CHEMBL3358983)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1coc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-25-17-8-12(9-18(26-2)20(17)27-3)19-21(24)22-10-15(23-19)14-11-28-16-7-5-4-6-13(14)16/h4-11H,1-3H3,(H,22,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192841
PNG
(CHEMBL3358969)
Show SMILES COc1cc(OC)cc(c1)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H17N3O3/c1-25-13-7-12(8-14(9-13)26-2)19-20(24)22-11-18(23-19)16-10-21-17-6-4-3-5-15(16)17/h3-11,21H,1-2H3,(H,22,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192851
PNG
(CHEMBL3358972)
Show SMILES CCOc1ccc(cc1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O3/c1-3-27-18-9-8-13(10-19(18)26-2)20-21(25)23-12-17(24-20)15-11-22-16-7-5-4-6-14(15)16/h4-12,22H,3H2,1-2H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192848
PNG
(CHEMBL3358995)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccccc1Cl
Show InChI InChI=1S/C19H17ClN2O4/c1-24-15-8-11(9-16(25-2)18(15)26-3)17-19(23)21-10-14(22-17)12-6-4-5-7-13(12)20/h4-10H,1-3H3,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant VEGFR3 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192842
PNG
(CHEMBL3358990)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccc[nH]1
Show InChI InChI=1S/C17H17N3O4/c1-22-13-7-10(8-14(23-2)16(13)24-3)15-17(21)19-9-12(20-15)11-5-4-6-18-11/h4-9,18H,1-3H3,(H,19,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50192846
PNG
(CHEMBL3358992)
Show SMILES COc1cccc(c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H20N2O5/c1-24-14-7-5-6-12(8-14)15-11-21-20(23)18(22-15)13-9-16(25-2)19(27-4)17(10-13)26-3/h5-11H,1-4H3,(H,21,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.40E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human c-KiT


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192855
PNG
(CHEMBL3358986)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccc2ccccc2c1
Show InChI InChI=1S/C23H20N2O4/c1-27-19-11-17(12-20(28-2)22(19)29-3)21-23(26)24-13-18(25-21)16-9-8-14-6-4-5-7-15(14)10-16/h4-13H,1-3H3,(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192875
PNG
(CHEMBL3359000)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccccc1
Show InChI InChI=1S/C19H18N2O4/c1-23-15-9-13(10-16(24-2)18(15)25-3)17-19(22)20-11-14(21-17)12-7-5-4-6-8-12/h4-11H,1-3H3,(H,20,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192865
PNG
(CHEMBL3358982)
Show SMILES COC(=O)c1ccc2c(c[nH]c2c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C23H21N3O6/c1-29-18-8-13(9-19(30-2)21(18)31-3)20-22(27)25-11-17(26-20)15-10-24-16-7-12(23(28)32-4)5-6-14(15)16/h5-11,24H,1-4H3,(H,25,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192861
PNG
(CHEMBL3359002)
Show SMILES COc1cc(cc(OC)c1OC)-c1c[nH]c(=O)c(n1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)16-11-23-21(25)19(24-16)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192852
PNG
(CHEMBL3358975)
Show SMILES Fc1ccc(cc1)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C18H12FN3O/c19-12-7-5-11(6-8-12)17-18(23)21-10-16(22-17)14-9-20-15-4-2-1-3-13(14)15/h1-10,20H,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192849
PNG
(CHEMBL3358973)
Show SMILES O=c1[nH]cc(nc1-c1ccc2OCOc2c1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C19H13N3O3/c23-19-18(11-5-6-16-17(7-11)25-10-24-16)22-15(9-21-19)13-8-20-14-4-2-1-3-12(13)14/h1-9,20H,10H2,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192853
PNG
(CHEMBL3358974)
Show SMILES O=c1[nH]cc(nc1-c1ccc(cc1)N1CCOCC1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H20N4O2/c27-22-21(15-5-7-16(8-6-15)26-9-11-28-12-10-26)25-20(14-24-22)18-13-23-19-4-2-1-3-17(18)19/h1-8,13-14,23H,9-12H2,(H,24,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192863
PNG
(CHEMBL3358979)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cn(C)c2ccccc12
Show InChI InChI=1S/C22H21N3O4/c1-25-12-15(14-7-5-6-8-17(14)25)16-11-23-22(26)20(24-16)13-9-18(27-2)21(29-4)19(10-13)28-3/h5-12H,1-4H3,(H,23,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192872
PNG
(CHEMBL3358998)
Show SMILES COc1ccc(c(F)c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H19FN2O5/c1-25-12-5-6-13(14(21)9-12)15-10-22-20(24)18(23-15)11-7-16(26-2)19(28-4)17(8-11)27-3/h5-10H,1-4H3,(H,22,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192843
PNG
(CHEMBL3358968)
Show SMILES COc1ccc(cc1)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C19H15N3O2/c1-24-13-8-6-12(7-9-13)18-19(23)21-11-17(22-18)15-10-20-16-5-3-2-4-14(15)16/h2-11,20H,1H3,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192840
PNG
(CHEMBL3358991)
Show SMILES COc1ccc(cc1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H20N2O5/c1-24-14-7-5-12(6-8-14)15-11-21-20(23)18(22-15)13-9-16(25-2)19(27-4)17(10-13)26-3/h5-11H,1-4H3,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50192846
PNG
(CHEMBL3358992)
Show SMILES COc1cccc(c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H20N2O5/c1-24-14-7-5-6-12(8-14)15-11-21-20(23)18(22-15)13-9-16(25-2)19(27-4)17(10-13)26-3/h5-11H,1-4H3,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192867
PNG
(CHEMBL3358984)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cnc2ccccc2c1
Show InChI InChI=1S/C22H19N3O4/c1-27-18-9-14(10-19(28-2)21(18)29-3)20-22(26)24-12-17(25-20)15-8-13-6-4-5-7-16(13)23-11-15/h4-12H,1-3H3,(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192844
PNG
(CHEMBL3358993)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C19H17ClN2O4/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)21-10-14(22-17)11-4-6-13(20)7-5-11/h4-10H,1-3H3,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.10E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192873
PNG
(CHEMBL3358976)
Show SMILES CCc1ccc(cc1)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H17N3O/c1-2-13-7-9-14(10-8-13)19-20(24)22-12-18(23-19)16-11-21-17-6-4-3-5-15(16)17/h3-12,21H,2H2,1H3,(H,22,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.20E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3.60E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FLT3 using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192862
PNG
(CHEMBL3358980)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2cc(F)ccc12
Show InChI InChI=1S/C21H18FN3O4/c1-27-17-6-11(7-18(28-2)20(17)29-3)19-21(26)24-10-16(25-19)14-9-23-15-8-12(22)4-5-13(14)15/h4-10,23H,1-3H3,(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 5.60E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50192850
PNG
(CHEMBL3358994)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccc(Cl)c1
Show InChI InChI=1S/C19H17ClN2O4/c1-24-15-8-12(9-16(25-2)18(15)26-3)17-19(23)21-10-14(22-17)11-5-4-6-13(20)7-11/h4-10H,1-3H3,(H,21,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.60E+4n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192845
PNG
(CHEMBL3358971)
Show SMILES COc1ccc(c(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-9-8-13(19(27-2)20(17)28-3)18-21(25)23-11-16(24-18)14-10-22-15-7-5-4-6-12(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant TIE2 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Aurora kinase B


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Aurora B using Tetra(LRRWSLG) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant SRC using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant AKT1 using GSK3/14-27 substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192864
PNG
(CHEMBL3359001)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(-c2c[nH]c3ccccc23)c(C)[nH]c1=O
Show InChI InChI=1S/C22H21N3O4/c1-12-19(15-11-23-16-8-6-5-7-14(15)16)25-20(22(26)24-12)13-9-17(27-2)21(29-4)18(10-13)28-3/h5-11,23H,1-4H3,(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Aurora kinase A


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Aurora A using Tetra(LRRWSLG) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Casein kinase II alpha


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CK2A1 using Casein substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 4 (CDK4)


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK4/Cyclin D1 using b-CTF substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 2 (CDK2)


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK2/cyclin A using histone H1 substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ERBB2 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
RAF serine/threonine protein kinase


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant B-RAF-VE using MEK1 KM substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MET using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192847
PNG
(CHEMBL3358970)
Show SMILES COc1cc(OC)c(c(OC)c1)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12 |(3.15,-16.43,;4.49,-17.21,;5.83,-16.43,;5.83,-14.88,;7.16,-14.12,;7.16,-12.58,;5.83,-11.82,;8.5,-14.88,;8.5,-16.42,;9.83,-17.18,;9.84,-18.71,;7.17,-17.2,;9.83,-14.11,;11.16,-14.87,;12.49,-14.11,;12.49,-12.57,;11.16,-11.79,;9.83,-12.57,;8.49,-11.8,;13.81,-14.88,;13.97,-16.42,;15.48,-16.75,;16.25,-15.41,;17.75,-15.08,;18.23,-13.63,;17.2,-12.49,;15.7,-12.81,;15.22,-14.26,)|
Show InChI InChI=1S/C21H19N3O4/c1-26-12-8-17(27-2)19(18(9-12)28-3)20-21(25)23-11-16(24-20)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PLK1 using Casein substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant IGF1R using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
NUAK family SNF1-like kinase 1


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ARK5


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 8


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant COT


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Ephrin receptor


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EPHB4 using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Insulin receptor


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant INSR using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK4


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant SAK


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
Focal adhesion kinase 1


(Homo sapiens (Human))
BDBM50192858
PNG
(CHEMBL3358966)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19-21(25)23-11-16(24-19)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAK using poly(Glu,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%