Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transporter (Rattus norvegicus (rat)) | BDBM364427 (US10913711, Compound 10a | US11555013, Compound 10...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron... | Citation and Details BindingDB Entry DOI: 10.7270/Q2ST7TRG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM364425 (US10913711, Compound 10d | US11555013, Compound 10...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | MCE PC cid PC sid UniChem | US Patent | >0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron... | Citation and Details BindingDB Entry DOI: 10.7270/Q2ST7TRG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50308250 ((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.135 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL | Assay Description Displacement of [N-methyl-3H]nisoxetine from rat hippocampus NET by filtration binding assay | J Med Chem 53: 2534-51 (2010) Article DOI: 10.1021/jm901818u BindingDB Entry DOI: 10.7270/Q2ST7PX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50124566 ((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 mins | Bioorg Med Chem 22: 311-24 (2013) Article DOI: 10.1016/j.bmc.2013.11.017 BindingDB Entry DOI: 10.7270/Q2FB54D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50198230 ((S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholin...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Glasgow Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysis | Bioorg Med Chem Lett 19: 4996-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.064 BindingDB Entry DOI: 10.7270/Q22V2G5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50322698 (rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 2.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NET in rat hippocampus after 2 hrs by liquid scintillation counting | J Med Chem 53: 4989-5001 (2010) Article DOI: 10.1021/jm100481d BindingDB Entry DOI: 10.7270/Q20V8DR3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM84745 (CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM84745 (CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AMRI Curated by ChEMBL | Assay Description Inhibition of rat NET | Bioorg Med Chem Lett 22: 7219-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.050 BindingDB Entry DOI: 10.7270/Q20K29QC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50297077 ((S)-N-(cyclobutylmethyl)-N-(pyrrolidin-3-yl)-2-(tr...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to rat NET expressed in HEK293 cells | Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50005548 ((+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinol...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of NET in rat synaptosomal membrane | ACS Med Chem Lett 4: 46-51 (2013) Article DOI: 10.1021/ml300262e BindingDB Entry DOI: 10.7270/Q2FQ9XXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50366567 (ATOMOXETINE) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50444862 (CHEMBL3099493) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 mins | Bioorg Med Chem 22: 311-24 (2013) Article DOI: 10.1016/j.bmc.2013.11.017 BindingDB Entry DOI: 10.7270/Q2FB54D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50330790 (CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM22417 (3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50444861 (CHEMBL3099494) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 mins | Bioorg Med Chem 22: 311-24 (2013) Article DOI: 10.1016/j.bmc.2013.11.017 BindingDB Entry DOI: 10.7270/Q2FB54D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50401730 (CHEMBL2206509) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AMRI Curated by ChEMBL | Assay Description Inhibition of rat NET | Bioorg Med Chem Lett 22: 7219-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.050 BindingDB Entry DOI: 10.7270/Q20K29QC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254049 ((S)-N-methyl-4-(naphthalen-1-yl)-4-(thiophen-2-yl)...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50444860 (CHEMBL3099495) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 mins | Bioorg Med Chem 22: 311-24 (2013) Article DOI: 10.1016/j.bmc.2013.11.017 BindingDB Entry DOI: 10.7270/Q2FB54D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50301211 ((2R,3S)-2-[(2-Iodophenoxy)phenylmethyl]morpholine ...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Glasgow Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysis | Bioorg Med Chem Lett 19: 4996-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.064 BindingDB Entry DOI: 10.7270/Q22V2G5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254073 ((S)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50190608 (CHEMBL213627 | cis-(3S,6S)-(6-benzhydryl-tetrahydr...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 mins | Bioorg Med Chem 22: 311-24 (2013) Article DOI: 10.1016/j.bmc.2013.11.017 BindingDB Entry DOI: 10.7270/Q2FB54D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254071 ((S)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50330791 (CHEMBL1277595 | N-Methyl-4-phenyl-4-(4-(2-(pyrroli...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50330787 (4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50136674 ((3R)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propa...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM84745 (CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50303309 (3-(3,4-dichlorophenyl)-2-nortropene | CHEMBL578130) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Orleans Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NET in rat brain | Bioorg Med Chem Lett 19: 6865-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.087 BindingDB Entry DOI: 10.7270/Q24T6K9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50005548 ((+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinol...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AMRI Curated by ChEMBL | Assay Description Inhibition of rat NET | Bioorg Med Chem Lett 22: 7219-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.050 BindingDB Entry DOI: 10.7270/Q20K29QC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50190601 ((2S,4R,5R)-2-benzhydryl-5-[(1H-indol-5-ylmethyl)-a...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 mins | Bioorg Med Chem 22: 311-24 (2013) Article DOI: 10.1016/j.bmc.2013.11.017 BindingDB Entry DOI: 10.7270/Q2FB54D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50190603 (CHEMBL211077 | cis-(3S,6S)-(6-benzhydryl-tetrahydr...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 mins | Bioorg Med Chem 22: 311-24 (2013) Article DOI: 10.1016/j.bmc.2013.11.017 BindingDB Entry DOI: 10.7270/Q2FB54D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM138157 (US8877798, Table 3, Structure 3) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurovance, Inc. US Patent | Assay Description Binding assay using NET, DAT and SERT enzyme. | US Patent US8877798 (2014) BindingDB Entry DOI: 10.7270/Q21R6P76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254111 ((S)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 35.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50444871 (CHEMBL3099502) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 mins | Bioorg Med Chem 22: 311-24 (2013) Article DOI: 10.1016/j.bmc.2013.11.017 BindingDB Entry DOI: 10.7270/Q2FB54D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50048803 (5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to rat NET | Bioorg Med Chem 16: 7291-301 (2008) Article DOI: 10.1016/j.bmc.2008.06.030 BindingDB Entry DOI: 10.7270/Q2ZP45XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254047 ((S)-N-methyl-3-(naphthalen-1-yl)-3-(thiophen-2-yl)...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 52.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50264064 ((2S,3S)-iodoreboxetine | (S)-2-((S)-(2-ethoxypheno...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 53.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Glasgow Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysis | Bioorg Med Chem Lett 19: 4996-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.064 BindingDB Entry DOI: 10.7270/Q22V2G5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50264063 ((2R,3S)-iodoreboxetine | (R)-2-((S)-(2-ethoxypheno...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 58.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Glasgow Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysis | Bioorg Med Chem Lett 19: 4996-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.064 BindingDB Entry DOI: 10.7270/Q22V2G5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50331515 (CHEMBL1708 | PAROXETINE | Paroxetine hydrochloride...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Orleans Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter in Sprague-Dawley rat frontal cortex after 1 hr by liquid scintillation counting | Bioorg Med Chem 18: 8356-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.060 BindingDB Entry DOI: 10.7270/Q2CN744P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254072 ((R)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 79.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM138155 (US8877798, Table 3, Structure 1) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurovance, Inc. US Patent | Assay Description Binding assay using NET, DAT and SERT enzyme. | US Patent US8877798 (2014) BindingDB Entry DOI: 10.7270/Q21R6P76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50330788 (CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254027 ((R)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM364387 (US10913711, Compound 2r | US11555013, Compound 2r ...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron... | Citation and Details BindingDB Entry DOI: 10.7270/Q2ST7TRG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50303311 (3-alpha-(4-Chlorophenyl)methoxy-3-beta-phenyl-nort...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Orleans Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NET in rat brain | Bioorg Med Chem Lett 19: 6865-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.087 BindingDB Entry DOI: 10.7270/Q24T6K9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254050 ((R)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 102 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254048 ((R)-N-methyl-4-(naphthalen-1-yl)-4-(thiophen-2-yl)...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50330789 (CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50303307 (3-(4-Chlorophenyl)-2-nortropene | CHEMBL576508) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Orleans Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NET in rat brain | Bioorg Med Chem Lett 19: 6865-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.087 BindingDB Entry DOI: 10.7270/Q24T6K9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50254046 ((R)-N-methyl-3-(naphthalen-1-yl)-3-(thiophen-2-yl)...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 139 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New York Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry | Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95 | |||||||||||
More data for this Ligand-Target Pair |
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