Compile Data Set for Download or QSAR

Found 200 hits with Last Name = 'prestwich' and Initial = 'gd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350715 (CHEMBL1818146) Show SMILES CCCCCCCCCCCCCC(=O)Nc1ccc(cc1)C(F)P(O)([O-])=O Show InChI InChI=1S/C21H35FNO4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-20(24)23-19-16-14-18(15-17-19)21(22)28(25,26)27/h14-17,21H,2-13H2,1H3,(H,23,24)(H2,25,26,27)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350716 (CHEMBL1818147) Show SMILES CCCCCCCCCCCCCC(=O)Nc1ccc(cc1)C(Br)P(O)([O-])=O Show InChI InChI=1S/C21H35BrNO4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-20(24)23-19-16-14-18(15-17-19)21(22)28(25,26)27/h14-17,21H,2-13H2,1H3,(H,23,24)(H2,25,26,27)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350713 (CHEMBL1818144) Show SMILES CCCCCCCCCCCCCC(=O)Nc1ccc(CP(O)([O-])=O)cc1 Show InChI InChI=1S/C21H36NO4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-21(23)22-20-16-14-19(15-17-20)18-27(24,25)26/h14-17H,2-13,18H2,1H3,(H,22,23)(H2,24,25,26)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350717 (CHEMBL1818148) Show SMILES CCCCCCCCCC(=O)Nc1ccc(CP(O)([O-])=O)cc1 Show InChI InChI=1S/C17H28NO4P/c1-2-3-4-5-6-7-8-9-17(19)18-16-12-10-15(11-13-16)14-23(20,21)22/h10-13H,2-9,14H2,1H3,(H,18,19)(H2,20,21,22)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350714 (CHEMBL1818145) Show SMILES CCCCCCCCCCCCCC(=O)Nc1ccc(cc1)C(=O)P(O)(O)[O-] Show InChI InChI=1S/C21H35NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-20(23)22-19-16-14-18(15-17-19)21(24)28(25,26)27/h14-17,25-26,28H,2-13H2,1H3,(H,22,23)/q-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350721 (CHEMBL1818149) Show SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)C(=O)P(O)(O)[O-] Show InChI InChI=1S/C17H27NO5P/c1-2-3-4-5-6-7-8-9-16(19)18-15-12-10-14(11-13-15)17(20)24(21,22)23/h10-13,21-22,24H,2-9H2,1H3,(H,18,19)/q-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Squalene monooxygenase (Homo sapiens (Human))	BDBM50018518 (((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-methyl-naphtha...) Show SMILES CN(C\C=C\C#CC(C)(C)C)Cc1cccc2ccccc12 Show InChI InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Apparent inhibitory constant of the compound against squalene epoxidase				J Med Chem 32: 2152-8 (1989) BindingDB Entry DOI: 10.7270/Q21835HM
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055641 (2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#16]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C29H50OS/c1-23(2)13-11-18-27(6)31-22-21-26(5)15-10-9-14-24(3)16-12-17-25(4)19-20-28-29(7,8)30-28/h13-15,17,27-28H,9-12,16,18-22H2,1-8H3/b24-14+,25-17+,26-15+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50193515 (1-fluoro-(3S)-hydroxyl-4-oleoyloxylbutane 1,3-cycl...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)P(O)(=O)O1 Show InChI InChI=1S/C22H42FO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(24)27-19-20-18-21(23)29(25,26)28-20/h20-21H,2-19H2,1H3,(H,25,26)/t20-,21?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assay				J Med Chem 49: 5309-15 (2006) Article DOI: 10.1021/jm060351+ BindingDB Entry DOI: 10.7270/Q2VM4BWW
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350718 (CHEMBL1818150) Show SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)C(F)P(O)([O-])=O Show InChI InChI=1S/C17H27FNO4P/c1-2-3-4-5-6-7-8-9-16(20)19-15-12-10-14(11-13-15)17(18)24(21,22)23/h10-13,17H,2-9H2,1H3,(H,19,20)(H2,21,22,23)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055642 (2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#16]-[#6]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C28H48OS/c1-23(2)13-11-21-30-22-12-18-25(4)15-9-8-14-24(3)16-10-17-26(5)19-20-27-28(6,7)29-27/h13-15,17,27H,8-12,16,18-22H2,1-7H3/b24-14+,25-15+,26-17+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50193518 (3-hydroxyl-4-palmitoyloxylbutane 1,3-cyclic phosph...) Show SMILES CCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 Show InChI InChI=1S/C20H39O4PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(21)23-18-19-16-17-25(22,26)24-19/h19H,2-18H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	314	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assay				J Med Chem 49: 5309-15 (2006) Article DOI: 10.1021/jm060351+ BindingDB Entry DOI: 10.7270/Q2VM4BWW
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50193517 (3-hydroxyl-4-oleoyloxylbutane 1,3-cyclic phosphono...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 Show InChI InChI=1S/C22H43O4PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(23)25-20-21-18-19-27(24,28)26-21/h21H,2-20H2,1H3,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	403	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assay				J Med Chem 49: 5309-15 (2006) Article DOI: 10.1021/jm060351+ BindingDB Entry DOI: 10.7270/Q2VM4BWW
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055643 (2,2-Dimethyl-3-[(E)-3-methyl-7-((3E,7E)-4,8,12-tri...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6])-[#16]-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6] Show InChI InChI=1S/C29H50OS/c1-23(2)13-9-14-24(3)15-10-16-25(4)18-12-22-31-27(6)19-11-17-26(5)20-21-28-29(7,8)30-28/h13,15,17-18,27-28H,9-12,14,16,19-22H2,1-8H3/b24-15+,25-18+,26-17+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350719 (CHEMBL1818151) Show SMILES CCCCCCC(=O)Nc1ccc(CP(O)([O-])=O)cc1 Show InChI InChI=1S/C14H22NO4P/c1-2-3-4-5-6-14(16)15-13-9-7-12(8-10-13)11-20(17,18)19/h7-10H,2-6,11H2,1H3,(H,15,16)(H2,17,18,19)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	512	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 3 (Homo sapiens (Human))	BDBM50193517 (3-hydroxyl-4-oleoyloxylbutane 1,3-cyclic phosphono...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 Show InChI InChI=1S/C22H43O4PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(23)25-20-21-18-19-27(24,28)26-21/h21H,2-20H2,1H3,(H,24,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	636	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Activity at human LPA3 receptor expressed in RH7777 cells by calcium mobilization assay				J Med Chem 49: 5309-15 (2006) Article DOI: 10.1021/jm060351+ BindingDB Entry DOI: 10.7270/Q2VM4BWW
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350720 (CHEMBL1818153) Show SMILES CCCCCCC(=O)Nc1ccc(cc1)C(F)P(O)([O-])=O Show InChI InChI=1S/C14H21FNO4P/c1-2-3-4-5-6-13(17)16-12-9-7-11(8-10-12)14(15)21(18,19)20/h7-10,14H,2-6H2,1H3,(H,16,17)(H2,18,19,20)/p-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	834	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50350722 (CHEMBL1818152) Show SMILES CCCCCCC(=O)Nc1ccc(cc1)C(=O)P(O)(O)[O-] Show InChI InChI=1S/C14H21NO5P/c1-2-3-4-5-6-13(16)15-12-9-7-11(8-10-12)14(17)21(18,19)20/h7-10,18-19,21H,2-6H2,1H3,(H,15,16)/q-1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...				Bioorg Med Chem Lett 21: 5098-101 (2011) Article DOI: 10.1016/j.bmcl.2011.03.068 BindingDB Entry DOI: 10.7270/Q2QN674N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 3 (Homo sapiens (Human))	BDBM50193518 (3-hydroxyl-4-palmitoyloxylbutane 1,3-cyclic phosph...) Show SMILES CCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1 Show InChI InChI=1S/C20H39O4PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(21)23-18-19-16-17-25(22,26)24-19/h19H,2-18H2,1H3,(H,22,26)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Activity at human LPA3 receptor expressed in RH7777 cells by calcium mobilization assay				J Med Chem 49: 5309-15 (2006) Article DOI: 10.1021/jm060351+ BindingDB Entry DOI: 10.7270/Q2VM4BWW
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055642 (2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#16]-[#6]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C28H48OS/c1-23(2)13-11-21-30-22-12-18-25(4)15-9-8-14-24(3)16-10-17-26(5)19-20-27-28(6,7)29-27/h13-15,17,27H,8-12,16,18-22H2,1-7H3/b24-14+,25-15+,26-17+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055641 (2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#16]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C29H50OS/c1-23(2)13-11-18-27(6)31-22-21-26(5)15-10-9-14-24(3)16-12-17-25(4)19-20-28-29(7,8)30-28/h13-15,17,27-28H,9-12,16,18-22H2,1-8H3/b24-14+,25-17+,26-15+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50110402 (CHEMBL3605581) Show SMILES [Cl-].CCCCCCCCCCCCC(=C)S(=O)(=O)CCC[N+](C)(C)C Show InChI InChI=1S/C20H42NO2S/c1-6-7-8-9-10-11-12-13-14-15-17-20(2)24(22,23)19-16-18-21(3,4)5/h2,6-19H2,1,3-5H3/q+1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of human ATX phosphodiesterase expressed in Sf9 cells assessed as hydrolysis of FS-3 measured after 5 to 25 mins by fluorescence assay				Bioorg Med Chem 23: 5999-6013 (2015) Article DOI: 10.1016/j.bmc.2015.06.054 BindingDB Entry DOI: 10.7270/Q2K9399W
					More data for this Ligand-Target Pair
Squalene monooxygenase (Homo sapiens (Human))	BDBM50286540 (1N-[20-(6-aminohexylamino)-4,8,13,17-tetramethyl-(...) Show SMILES C\C(CCCNCCCCCCN)=C/CC\C(C)=C\CCC=C(C)CC\C=C(/C)CCCNC1CC1 Show InChI InChI=1S/C33H61N3/c1-29(17-11-19-31(3)21-13-27-35-26-10-6-5-9-25-34)15-7-8-16-30(2)18-12-20-32(4)22-14-28-36-33-23-24-33/h15-16,19-20,33,35-36H,5-14,17-18,21-28,34H2,1-4H3/b29-15+,30-16+,31-19+,32-20+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	8.8	n/a
TBA Curated by ChEMBL					Assay Description The compound was tested for its inhibitory activity against pig Squalene epoxidase at pH 7.4				Bioorg Med Chem Lett 5: 481-486 (1995) Article DOI: 10.1016/0960-894X(95)00058-2 BindingDB Entry DOI: 10.7270/Q2HH6K2N
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50110424 (CHEMBL3605579) Show SMILES [Cl-].CCCCCCCC\C=C/CCCCCCCCC(=C)S(=O)(=O)CCC[N+](C)(C)C Show InChI InChI=1S/C26H52NO2S/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-26(2)30(28,29)25-22-24-27(3,4)5/h13-14H,2,6-12,15-25H2,1,3-5H3/q+1/b14-13-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of human ATX phosphodiesterase expressed in Sf9 cells assessed as hydrolysis of FS-3 measured after 5 to 25 mins by fluorescence assay				Bioorg Med Chem 23: 5999-6013 (2015) Article DOI: 10.1016/j.bmc.2015.06.054 BindingDB Entry DOI: 10.7270/Q2K9399W
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055644 (2-Methyl-3-((7E,11E,15Z)-3,7,12,20-tetramethyl-16-...) Show SMILES [#6]-[#6](-[#6]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]=[#6])-[#6]-[#6]-[#6]-1-[#8]-[#6]-1-[#6] Show InChI InChI=1S/C30H50O/c1-8-29(20-11-14-24(2)3)21-13-19-26(5)16-10-9-15-25(4)17-12-18-27(6)22-23-30-28(7)31-30/h8,14-16,21,27-28,30H,1,9-13,17-20,22-23H2,2-7H3/b25-15+,26-16+,29-21+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50290988 (2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6]=[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6@@H]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C31H50O/c1-9-29(21-12-15-25(2)3)22-14-20-27(5)17-11-10-16-26(4)18-13-19-28(6)23-24-30-31(7,8)32-30/h9,15-17,19,22,30H,1,10-14,18,20-21,23-24H2,2-8H3/b26-16+,27-17+,28-19+,29-22+/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)				Bioorg Med Chem Lett 7: 309-314 (1997) Article DOI: 10.1016/S0960-894X(97)00008-5 BindingDB Entry DOI: 10.7270/Q26H4HDR
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 3 (Homo sapiens (Human))	BDBM50193515 (1-fluoro-(3S)-hydroxyl-4-oleoyloxylbutane 1,3-cycl...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)P(O)(=O)O1 Show InChI InChI=1S/C22H42FO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(24)27-19-20-18-21(23)29(25,26)28-20/h20-21H,2-19H2,1H3,(H,25,26)/t20-,21?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Activity at human LPA3 receptor expressed in RH7777 cells by calcium mobilization assay				J Med Chem 49: 5309-15 (2006) Article DOI: 10.1021/jm060351+ BindingDB Entry DOI: 10.7270/Q2VM4BWW
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50110403 (CHEMBL3605580) Show SMILES [Cl-].CCCCCCCCCCCCCCCCC(=C)S(=O)(=O)CCC[N+](C)(C)C Show InChI InChI=1S/C24H50NO2S/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24(2)28(26,27)23-20-22-25(3,4)5/h2,6-23H2,1,3-5H3/q+1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of human ATX phosphodiesterase expressed in Sf9 cells assessed as hydrolysis of FS-3 measured after 5 to 25 mins by fluorescence assay				Bioorg Med Chem 23: 5999-6013 (2015) Article DOI: 10.1016/j.bmc.2015.06.054 BindingDB Entry DOI: 10.7270/Q2K9399W
					More data for this Ligand-Target Pair
Squalene monooxygenase (Homo sapiens (Human))	BDBM50279929 ((2Z,6E,10E,14E)-6,11,15,19-Tetramethyl-2-(4-methyl...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6]-[#8])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6] Show InChI InChI=1S/C30H50O/c1-25(2)14-10-18-29(7)20-12-19-27(5)16-8-9-17-28(6)21-13-23-30(24-31)22-11-15-26(3)4/h14-17,20,23,31H,8-13,18-19,21-22,24H2,1-7H3/b27-16+,28-17+,29-20+,30-23-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound was measured against partially purified pig liver Squalene epoxidase (SE).				Bioorg Med Chem Lett 1: 227-232 (1991) Article DOI: 10.1016/S0960-894X(00)80258-9 BindingDB Entry DOI: 10.7270/Q27S7NP6
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055644 (2-Methyl-3-((7E,11E,15Z)-3,7,12,20-tetramethyl-16-...) Show SMILES [#6]-[#6](-[#6]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]=[#6])-[#6]-[#6]-[#6]-1-[#8]-[#6]-1-[#6] Show InChI InChI=1S/C30H50O/c1-8-29(20-11-14-24(2)3)21-13-19-26(5)16-10-9-15-25(4)17-12-18-27(6)22-23-30-28(7)31-30/h8,14-16,21,27-28,30H,1,9-13,17-20,22-23H2,2-7H3/b25-15+,26-16+,29-21+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055640 (3-[(3E,7E)-11-((E)-4,8-Dimethyl-nona-3,7-dienylsul...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#16]-[#6]-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C28H48OS/c1-23(2)13-10-15-25(4)18-12-22-30-21-9-8-14-24(3)16-11-17-26(5)19-20-27-28(6,7)29-27/h13-14,17-18,27H,8-12,15-16,19-22H2,1-7H3/b24-14+,25-18+,26-17+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50290991 (2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...) Show SMILES CC(C)CCC\C(C=C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CC[C@@H]1OC1(C)C Show InChI InChI=1S/C31H52O/c1-9-29(21-12-15-25(2)3)22-14-20-27(5)17-11-10-16-26(4)18-13-19-28(6)23-24-30-31(7,8)32-30/h9,16-17,19,22,25,30H,1,10-15,18,20-21,23-24H2,2-8H3/b26-16+,27-17+,28-19+,29-22+/t30-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)				Bioorg Med Chem Lett 7: 309-314 (1997) Article DOI: 10.1016/S0960-894X(97)00008-5 BindingDB Entry DOI: 10.7270/Q26H4HDR
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae (Baker's yeast))	BDBM50144314 ((2E,4E,6E,8E)-3,7,11-trimethyldodeca-2,4,6,8,10-pe...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]=[#6]/[#6](/[#6])=[#6]/[#6]=[#6]/[#6](/[#6])=[#6]/[#6]-[#8]P([#8])(=O)[#8]P([#8])([#8])=O Show InChI InChI=1S/C15H24O7P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18/h5-11H,12H2,1-4H3,(H,19,20)(H2,16,17,18)/b8-5+,10-6+,14-9+,15-11+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Dissociation constant against yeast farnesyltransferase				Bioorg Med Chem Lett 14: 2137-40 (2004) Article DOI: 10.1016/j.bmcl.2004.02.077 BindingDB Entry DOI: 10.7270/Q2S181Z3
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50290992 (3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6@@H]1-[#8]C1([#6])[#6])\[#6]=[#6](/F)F Show InChI InChI=1S/C31H48F2O/c1-24(2)13-10-19-28(23-30(32)33)20-12-18-26(4)15-9-8-14-25(3)16-11-17-27(5)21-22-29-31(6,7)34-29/h13-15,17,20,23,29H,8-12,16,18-19,21-22H2,1-7H3/b25-14+,26-15+,27-17+,28-20-/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...				Bioorg Med Chem Lett 7: 309-314 (1997) Article DOI: 10.1016/S0960-894X(97)00008-5 BindingDB Entry DOI: 10.7270/Q26H4HDR
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50290989 (3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6]-[#6]\[#6](=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6@@H]1-[#8]C1([#6])[#6])\[#6]=[#6](/F)F Show InChI InChI=1S/C31H50F2O/c1-24(2)13-10-19-28(23-30(32)33)20-12-18-26(4)15-9-8-14-25(3)16-11-17-27(5)21-22-29-31(6,7)34-29/h14-15,17,20,23-24,29H,8-13,16,18-19,21-22H2,1-7H3/b25-14+,26-15+,27-17+,28-20-/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)				Bioorg Med Chem Lett 7: 309-314 (1997) Article DOI: 10.1016/S0960-894X(97)00008-5 BindingDB Entry DOI: 10.7270/Q26H4HDR
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055645 ((6E,10E,14E)-2,6,10,15,19-Pentamethyl-21-(3-methyl...) Show SMILES CC(C)CCC(=O)C(C)C=CC\C(C)=C\CC\C=C(/C)CCCC(C)CCC1OC1C |w:9.8| Show InChI InChI=1S/C29H50O2/c1-22(2)18-20-28(30)26(6)17-11-16-24(4)13-9-8-12-23(3)14-10-15-25(5)19-21-29-27(7)31-29/h11-13,17,22,25-27,29H,8-10,14-16,18-21H2,1-7H3/b17-11?,23-12+,24-13+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Inhibition constant against rat liver Oxidosqualene-lanosterol cyclase				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Squalene monooxygenase (Homo sapiens (Human))	BDBM50018524 (6,10,15,19,23-Pentamethyl-tetracosa-6,10,14,18,22-...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6](-[#8])C#C Show InChI InChI=1S/C29H46O/c1-8-29(30)23-22-28(7)21-13-19-26(5)16-10-9-15-25(4)18-12-20-27(6)17-11-14-24(2)3/h1,14-16,20-21,29-30H,9-13,17-19,22-23H2,2-7H3/b25-15+,26-16+,27-20+,28-21+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Apparent inhibitory constant of the compound against squalene epoxidase				J Med Chem 32: 2152-8 (1989) BindingDB Entry DOI: 10.7270/Q21835HM
					More data for this Ligand-Target Pair
Squalene monooxygenase (Homo sapiens (Human))	BDBM50018522 (6,10,15,19-Tetramethyl-tetracosa-6,10,14,18-tetrae...) Show SMILES C\C(CC\C=C(/C)CCC(O)C#C)=C/CC\C=C(/C)CC\C=C(/C)CCC(O)C#C Show InChI InChI=1S/C28H42O2/c1-7-27(29)21-19-25(5)17-11-15-23(3)13-9-10-14-24(4)16-12-18-26(6)20-22-28(30)8-2/h1-2,13-14,17-18,27-30H,9-12,15-16,19-22H2,3-6H3/b23-13+,24-14+,25-17+,26-18+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans Squalene Epoxidase				J Med Chem 32: 2152-8 (1989) BindingDB Entry DOI: 10.7270/Q21835HM
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50055641 (2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#16]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C29H50OS/c1-23(2)13-11-18-27(6)31-22-21-26(5)15-10-9-14-24(3)16-12-17-25(4)19-20-28-29(7,8)30-28/h13-15,17,27-28H,9-12,16,18-22H2,1-8H3/b24-14+,25-17+,26-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicans				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50055642 (2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#16]-[#6]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C28H48OS/c1-23(2)13-11-21-30-22-12-18-25(4)15-9-8-14-24(3)16-10-17-26(5)19-20-27-28(6,7)29-27/h13-15,17,27H,8-12,16,18-22H2,1-7H3/b24-14+,25-15+,26-17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicans				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50133285 ((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...) Show SMILES C[NH+](CCCCCCOc1ccc(C(=O)c2ccc(Cl)cc2)c(F)c1)CC=C Show InChI InChI=1S/C23H27ClFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in T. brucei				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50133285 ((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...) Show SMILES C[NH+](CCCCCCOc1ccc(C(=O)c2ccc(Cl)cc2)c(F)c1)CC=C Show InChI InChI=1S/C23H27ClFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in P. carinii				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50095601 (CHEMBL25405 | [4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)...) Show SMILES Clc1ccc(cc1)C(=O)c1ccc(OC2CN3CCC2CC3)cc1 |THB:13:14:20.21:18.17,(8.94,-7.02,;7.44,-6.62,;7.03,-5.14,;5.55,-4.75,;4.47,-5.85,;4.87,-7.34,;6.36,-7.72,;2.98,-5.45,;1.89,-6.55,;2.57,-3.96,;1.08,-3.58,;.68,-2.09,;1.76,-.99,;1.36,.49,;-.13,.89,;-1.37,.23,;-2.35,1.8,;-4.22,1.75,;-2.98,2.49,;-1.1,2.42,;-.62,3.39,;-1.73,3.01,;3.25,-1.38,;3.65,-2.86,)| Show InChI InChI=1S/C20H20ClNO2/c21-17-5-1-15(2-6-17)20(23)16-3-7-18(8-4-16)24-19-13-22-11-9-14(19)10-12-22/h1-8,14,19H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in T. brucei				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50133285 ((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...) Show SMILES C[NH+](CCCCCCOc1ccc(C(=O)c2ccc(Cl)cc2)c(F)c1)CC=C Show InChI InChI=1S/C23H27ClFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3/p+1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in rat				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055641 (2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#16]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6] Show InChI InChI=1S/C29H50OS/c1-23(2)13-11-18-27(6)31-22-21-26(5)15-10-9-14-24(3)16-12-17-25(4)19-20-28-29(7,8)30-28/h13-15,17,27-28H,9-12,16,18-22H2,1-8H3/b24-14+,25-17+,26-15+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from rat liver				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50133285 ((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...) Show SMILES C[NH+](CCCCCCOc1ccc(C(=O)c2ccc(Cl)cc2)c(F)c1)CC=C Show InChI InChI=1S/C23H27ClFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in T. cruzi				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50095601 (CHEMBL25405 | [4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)...) Show SMILES Clc1ccc(cc1)C(=O)c1ccc(OC2CN3CCC2CC3)cc1 |THB:13:14:20.21:18.17,(8.94,-7.02,;7.44,-6.62,;7.03,-5.14,;5.55,-4.75,;4.47,-5.85,;4.87,-7.34,;6.36,-7.72,;2.98,-5.45,;1.89,-6.55,;2.57,-3.96,;1.08,-3.58,;.68,-2.09,;1.76,-.99,;1.36,.49,;-.13,.89,;-1.37,.23,;-2.35,1.8,;-4.22,1.75,;-2.98,2.49,;-1.1,2.42,;-.62,3.39,;-1.73,3.01,;3.25,-1.38,;3.65,-2.86,)| Show InChI InChI=1S/C20H20ClNO2/c21-17-5-1-15(2-6-17)20(23)16-3-7-18(8-4-16)24-19-13-22-11-9-14(19)10-12-22/h1-8,14,19H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in P. carinii				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50193515 (1-fluoro-(3S)-hydroxyl-4-oleoyloxylbutane 1,3-cycl...) Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)P(O)(=O)O1 Show InChI InChI=1S/C22H42FO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(24)27-19-20-18-21(23)29(25,26)28-20/h20-21H,2-19H2,1H3,(H,25,26)/t20-,21?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
The University of Utah Curated by ChEMBL					Assay Description Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assay				J Med Chem 49: 5309-15 (2006) Article DOI: 10.1021/jm060351+ BindingDB Entry DOI: 10.7270/Q2VM4BWW
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50055639 (2-Methyl-2-(4-methyl-pent-3-enyl)-3-[(3E,7E)-3,8,1...) Show SMILES [#6]-[#6](-[#6]-[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]1-[#8]C1([#6])[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6]-[#6]-1-[#8]-[#6]-1-[#6] Show InChI InChI=1S/C29H50O2/c1-22(2)12-11-21-29(7)28(31-29)20-18-24(4)14-9-8-13-23(3)15-10-16-25(5)17-19-27-26(6)30-27/h12-14,25-28H,8-11,15-21H2,1-7H3/b23-13+,24-14+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Inhibition against rat liver Oxidosqualene-lanosterol cyclase				J Med Chem 40: 201-9 (1997) Article DOI: 10.1021/jm960483a BindingDB Entry DOI: 10.7270/Q2P26X73
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50095601 (CHEMBL25405 | [4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)...) Show SMILES Clc1ccc(cc1)C(=O)c1ccc(OC2CN3CCC2CC3)cc1 |THB:13:14:20.21:18.17,(8.94,-7.02,;7.44,-6.62,;7.03,-5.14,;5.55,-4.75,;4.47,-5.85,;4.87,-7.34,;6.36,-7.72,;2.98,-5.45,;1.89,-6.55,;2.57,-3.96,;1.08,-3.58,;.68,-2.09,;1.76,-.99,;1.36,.49,;-.13,.89,;-1.37,.23,;-2.35,1.8,;-4.22,1.75,;-2.98,2.49,;-1.1,2.42,;-.62,3.39,;-1.73,3.01,;3.25,-1.38,;3.65,-2.86,)| Show InChI InChI=1S/C20H20ClNO2/c21-17-5-1-15(2-6-17)20(23)16-3-7-18(8-4-16)24-19-13-22-11-9-14(19)10-12-22/h1-8,14,19H,9-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in rat				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair

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