Compile Data Set for Download or QSAR

Found 57 hits with Last Name = 'bosch' and Initial = 'fu'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331273 (3-(6-methyl-1H-indol-2-yl)-1H-indazole-6-carbonitr...) Show SMILES Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cc(ccc12)C#N Show InChI InChI=1S/C17H12N4/c1-10-2-4-12-8-16(19-14(12)6-10)17-13-5-3-11(9-18)7-15(13)20-21-17/h2-8,19H,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331280 (3-(6-methyl-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyrid...) Show SMILES Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4/c1-9-4-5-10-8-13(17-12(10)7-9)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331269 (3-(1H-indol-2-yl)-1H-indazole-6-carbonitrile | CHE...) Show SMILES N#Cc1ccc2c(n[nH]c2c1)-c1cc2ccccc2[nH]1 Show InChI InChI=1S/C16H10N4/c17-9-10-5-6-12-14(7-10)19-20-16(12)15-8-11-3-1-2-4-13(11)18-15/h1-8,18H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331268 (3-(1H-indol-2-yl)-1H-indazole-5-carbonitrile | CHE...) Show SMILES N#Cc1ccc2[nH]nc(-c3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C16H10N4/c17-9-10-5-6-14-12(7-10)16(20-19-14)15-8-11-3-1-2-4-13(11)18-15/h1-8,18H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331274 (6-fluoro-3-(6-methoxy-1H-indol-2-yl)-1H-indazole |...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cc(F)ccc12 Show InChI InChI=1S/C16H12FN3O/c1-21-11-4-2-9-6-15(18-13(9)8-11)16-12-5-3-10(17)7-14(12)19-20-16/h2-8,18H,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331271 (6-methyl-3-(6-methyl-1H-indol-2-yl)-1H-indazole | ...) Show SMILES Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cc(C)ccc12 Show InChI InChI=1S/C17H15N3/c1-10-3-5-12-9-16(18-14(12)7-10)17-13-6-4-11(2)8-15(13)19-20-17/h3-9,18H,1-2H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331262 (3-(6-methyl-1H-indol-2-yl)-1H-indazole | CHEMBL128...) Show SMILES Cc1ccc2cc([nH]c2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C16H13N3/c1-10-6-7-11-9-15(17-14(11)8-10)16-12-4-2-3-5-13(12)18-19-16/h2-9,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331258 (3-(5-methoxy-1H-indol-2-yl)-1H-indazole | CHEMBL12...) Show SMILES COc1ccc2[nH]c(cc2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C16H13N3O/c1-20-11-6-7-13-10(8-11)9-15(17-13)16-12-4-2-3-5-14(12)18-19-16/h2-9,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331259 (3-(6-methoxy-1H-indol-2-yl)-1H-indazole | CHEMBL12...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C16H13N3O/c1-20-11-7-6-10-8-15(17-14(10)9-11)16-12-4-2-3-5-13(12)18-19-16/h2-9,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331272 (6-fluoro-3-(6-methyl-1H-indol-2-yl)-1H-indazole | ...) Show SMILES Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cc(F)ccc12 Show InChI InChI=1S/C16H12FN3/c1-9-2-3-10-7-15(18-13(10)6-9)16-12-5-4-11(17)8-14(12)19-20-16/h2-8,18H,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331257 (3-(1H-indol-2-yl)-1H-indazole | CHEMBL1288974) Show SMILES c1c([nH]c2ccccc12)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C15H11N3/c1-3-7-12-10(5-1)9-14(16-12)15-11-6-2-4-8-13(11)17-18-15/h1-9,16H,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331265 (3-(1H-indol-2-yl)-6-methyl-1H-indazole | CHEMBL128...) Show SMILES Cc1ccc2c(n[nH]c2c1)-c1cc2ccccc2[nH]1 Show InChI InChI=1S/C16H13N3/c1-10-6-7-12-14(8-10)18-19-16(12)15-9-11-4-2-3-5-13(11)17-15/h2-9,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331266 (5-fluoro-3-(1H-indol-2-yl)-1H-indazole | CHEMBL128...) Show SMILES Fc1ccc2[nH]nc(-c3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C15H10FN3/c16-10-5-6-13-11(8-10)15(19-18-13)14-7-9-3-1-2-4-12(9)17-14/h1-8,17H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of Aurora A				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331267 (6-fluoro-3-(1H-indol-2-yl)-1H-indazole | CHEMBL128...) Show SMILES Fc1ccc2c(n[nH]c2c1)-c1cc2ccccc2[nH]1 Show InChI InChI=1S/C15H10FN3/c16-10-5-6-11-13(8-10)18-19-15(11)14-7-9-3-1-2-4-12(9)17-14/h1-8,17H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331275 (3-(1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridine | CHE...) Show SMILES c1c([nH]c2ccccc12)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C14H10N4/c1-2-5-10-9(4-1)8-12(16-10)14-13-11(17-18-14)6-3-7-15-13/h1-8,16H,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331282 (3-(6-bromo-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridi...) Show SMILES Brc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C14H9BrN4/c15-9-4-3-8-6-12(17-11(8)7-9)14-13-10(18-19-14)2-1-5-16-13/h1-7,17H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331281 (3-(4-bromo-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridi...) Show SMILES Brc1cccc2[nH]c(cc12)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C14H9BrN4/c15-9-3-1-4-10-8(9)7-12(17-10)14-13-11(18-19-14)5-2-6-16-13/h1-7,17H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331264 (3-(1H-indol-2-yl)-5-methyl-1H-indazole | CHEMBL128...) Show SMILES Cc1ccc2[nH]nc(-c3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C16H13N3/c1-10-6-7-14-12(8-10)16(19-18-14)15-9-11-4-2-3-5-13(11)17-15/h2-9,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of Aurora B				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331276 (3-(5-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2[nH]c(cc2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-4-5-11-9(7-10)8-13(17-11)15-14-12(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331279 (3-(5-methyl-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyrid...) Show SMILES Cc1ccc2[nH]c(cc2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4/c1-9-4-5-11-10(7-9)8-13(17-11)15-14-12(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331270 (5-methyl-3-(6-methyl-1H-indol-2-yl)-1H-indazole | ...) Show SMILES Cc1ccc2cc([nH]c2c1)-c1n[nH]c2ccc(C)cc12 Show InChI InChI=1S/C17H15N3/c1-10-4-6-14-13(7-10)17(20-19-14)16-9-12-5-3-11(2)8-15(12)18-16/h3-9,18H,1-2H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331261 (3-(5-methyl-1H-indol-2-yl)-1H-indazole | CHEMBL128...) Show SMILES Cc1ccc2[nH]c(cc2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C16H13N3/c1-10-6-7-13-11(8-10)9-15(17-13)16-12-4-2-3-5-14(12)18-19-16/h2-9,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of CDK4/Cyclin D1				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of MEK-1				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50331283 (CHEMBL1288651 | N-(4-methoxyphenyl)-1H-indazole-3-...) Show SMILES COc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 Show InChI InChI=1S/C15H13N3O2/c1-20-11-8-6-10(7-9-11)16-15(19)14-12-4-2-3-5-13(12)17-18-14/h2-9H,1H3,(H,16,19)(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Nek2 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of NEK-2				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK4 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of SAK				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331263 (2-(1H-indazol-3-yl)-1H-indole-6-carboxylic acid | ...) Show SMILES OC(=O)c1ccc2cc([nH]c2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C16H11N3O2/c20-16(21)10-6-5-9-7-14(17-13(9)8-10)15-11-3-1-2-4-12(11)18-19-15/h1-8,17H,(H,18,19)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of CDK1/Cyclin B				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin A				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of FAK				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Wee1-like protein kinase (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of WEE1				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of CHK1				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of CDK5/p25				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of ABL1				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of TTK				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331260 (3-(7-methoxy-1H-indol-2-yl)-1H-indazole | CHEMBL12...) Show SMILES COc1cccc2cc([nH]c12)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C16H13N3O/c1-20-14-8-4-5-10-9-13(17-15(10)14)16-11-6-2-3-7-12(11)18-19-16/h2-9,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of PKC-theta				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331278 (3-(7-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1cccc2cc([nH]c12)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-12-6-2-4-9-8-11(17-13(9)12)15-14-10(18-19-15)5-3-7-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Lymphokine-activated killer T-cell-originated protein kinase (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of PBK				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Death-associated protein kinase 1 (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of DAPK1				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50331277 (3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyri...) Show SMILES COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C15H12N4O/c1-20-10-5-4-9-7-13(17-12(9)8-10)15-14-11(18-19-15)3-2-6-16-14/h2-8,17H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of PKC-beta1				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair

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