Compile Data Set for Download or QSAR

Found 66 hits with Last Name = 'roth' and Initial = 'mg'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434228 (CHEMBL2385512) Show SMILES CC(C)c1cc(c(C)cc1Oc1ccccc1)-c1cc(C(O)=O)c2cc(F)ccc2n1 Show InChI InChI=1S/C26H22FNO3/c1-15(2)19-13-20(16(3)11-25(19)31-18-7-5-4-6-8-18)24-14-22(26(29)30)21-12-17(27)9-10-23(21)28-24/h4-15H,1-3H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM15339 (6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...) Show SMILES Cc1c(nc2ccc(F)cc2c1C(O)=O)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C23H15F2NO2/c1-13-21(23(27)28)18-12-16(24)10-11-20(18)26-22(13)15-8-6-14(7-9-15)17-4-2-3-5-19(17)25/h2-12H,1H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM14711 (Asinex compound no. 6 | N-(3,5-Dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-12(3-2-4-13(8)18(20)21)14(19)17-11-6-9(15)5-10(16)7-11/h2-7H,1H3,(H,17,19)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434229 (CHEMBL2385511) Show SMILES Cc1cc(cc(C)c1Oc1ccccc1)-c1cc(C(O)=O)c2cc(F)ccc2n1 Show InChI InChI=1S/C24H18FNO3/c1-14-10-16(11-15(2)23(14)29-18-6-4-3-5-7-18)22-13-20(24(27)28)19-12-17(25)8-9-21(19)26-22/h3-13H,1-2H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434230 (CHEMBL2385510) Show SMILES CC(C)(C)c1ccc(Oc2ccc(cc2)-c2cc(C(O)=O)c3cc(F)ccc3n2)cc1 Show InChI InChI=1S/C26H22FNO3/c1-26(2,3)17-6-11-20(12-7-17)31-19-9-4-16(5-10-19)24-15-22(25(29)30)21-14-18(27)8-13-23(21)28-24/h4-15H,1-3H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair
Protein Wnt-2 (Mus musculus (Mouse))	BDBM36414 (CID15993586 | trans-N-Benzyl-4-((1-((2-cyanophenyl...) Show SMILES [H][C@]1(Cn2c(=O)n(Cc3ccccc3C#N)c3ccccc3c2=O)CC[C@@]([H])(CC1)C(=O)NCc1ccccc1 |r,wU:1.1,26.29,wD:1.0,26.33,(-1.18,-1.6,;0,-2.59,;-1.54,-2.59,;-2.31,-1.26,;-3.85,-1.26,;-4.61,-2.59,;-4.62,.07,;-6.15,.07,;-6.92,1.4,;-6.15,2.74,;-6.92,4.07,;-8.46,4.07,;-9.23,2.74,;-8.46,1.4,;-9.23,.07,;-10,-1.26,;-3.85,1.41,;-4.62,2.74,;-3.85,4.08,;-2.31,4.08,;-1.54,2.74,;-2.31,1.41,;-1.54,.07,;,.07,;.77,-1.25,;2.31,-1.25,;3.08,-2.59,;3.94,-3.87,;2.31,-3.92,;.77,-3.92,;4.62,-2.59,;5.38,-1.26,;5.38,-3.92,;6.92,-3.92,;7.69,-2.59,;6.92,-1.25,;7.69,.08,;9.23,.08,;10,-1.25,;9.23,-2.59,)| Show InChI InChI=1S/C31H30N4O3/c32-18-25-10-4-5-11-26(25)21-34-28-13-7-6-12-27(28)30(37)35(31(34)38)20-23-14-16-24(17-15-23)29(36)33-19-22-8-2-1-3-9-22/h1-13,23-24H,14-17,19-21H2,(H,33,36)/t23-,24-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Inhibition assay of Wnt response treated with exogenously supplied of Wnt protein ('exogenous Wnt' test)				Nat Chem Biol 5: 100-7 (2009) Article DOI: 10.1038/nchembio.137 BindingDB Entry DOI: 10.7270/Q2HX1B20
					More data for this Ligand-Target Pair
Protein Wnt-2 (Mus musculus (Mouse))	BDBM36412 (CID25093486 | N-(4-Methylquinolin-8-yl)-4-(endo-4-...) Show SMILES [H][C@]12C[C@]([H])(C=C1)c1c(O)n(c(O)c21)-c1ccc(cc1)C(=O)Nc1cccc2c(C)ccnc12 |c:5| Show InChI InChI=1S/C26H21N3O3/c1-14-11-12-27-23-19(14)3-2-4-20(23)28-24(30)15-7-9-18(10-8-15)29-25(31)21-16-5-6-17(13-16)22(21)26(29)32/h2-12,16-17,31-32H,13H2,1H3,(H,28,30)/t16-,17+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Inhibition assay of Wnt response treated with exogenously supplied of Wnt protein ('exogenous Wnt' test)				Nat Chem Biol 5: 100-7 (2009) Article DOI: 10.1038/nchembio.137 BindingDB Entry DOI: 10.7270/Q2HX1B20
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434231 (CHEMBL2385515) Show SMILES OC(=O)c1cc(nc2ccc(F)cc12)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C22H14FNO3/c23-15-8-11-20-18(12-15)19(22(25)26)13-21(24-20)14-6-9-17(10-7-14)27-16-4-2-1-3-5-16/h1-13H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair
Protein Wnt-2 (Mus musculus (Mouse))	BDBM36413 (CID15995771 | trans-N-Benzyl-4-((1-((6-methyl-4-ox...) Show SMILES [H][C@]1(Cn2c(=O)n(Cc3cc(=O)n4c(C)cccc4n3)c3ccccc3c2=O)CC[C@@]([H])(CC1)C(=O)NCc1ccccc1 |r,wU:1.1,30.34,wD:1.0,30.38,(-.8,-3.01,;.38,-4,;-1.16,-4,;-1.92,-2.67,;-3.46,-2.67,;-4.23,-4,;-4.23,-1.33,;-5.77,-1.33,;-6.54,-0,;-8.08,-0,;-8.85,1.33,;-10.38,1.33,;-8.08,2.66,;-8.85,4,;-10.38,4,;-8.08,5.33,;-6.54,5.33,;-5.77,4,;-6.54,2.66,;-5.77,1.33,;-3.46,0,;-4.23,1.33,;-3.46,2.67,;-1.92,2.67,;-1.15,1.33,;-1.92,0,;-1.15,-1.33,;.38,-1.33,;1.15,-2.66,;2.69,-2.66,;3.46,-4,;4.33,-5.27,;2.69,-5.33,;1.15,-5.33,;5,-4,;5.77,-2.67,;5.77,-5.33,;7.3,-5.33,;8.07,-4,;7.3,-2.66,;8.07,-1.33,;9.61,-1.33,;10.38,-2.66,;9.61,-4,)| Show InChI InChI=1S/C33H33N5O4/c1-22-8-7-13-29-35-26(18-30(39)38(22)29)21-36-28-12-6-5-11-27(28)32(41)37(33(36)42)20-24-14-16-25(17-15-24)31(40)34-19-23-9-3-2-4-10-23/h2-13,18,24-25H,14-17,19-21H2,1H3,(H,34,40)/t24-,25-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Inhibition assay of Wnt response treated with exogenously supplied of Wnt protein ('exogenous Wnt' test)				Nat Chem Biol 5: 100-7 (2009) Article DOI: 10.1038/nchembio.137 BindingDB Entry DOI: 10.7270/Q2HX1B20
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM14710 (ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...) Show SMILES Cc1cc(Br)ccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H14BrNO/c1-12-10-16(19)8-9-17(12)20-18(21)15-7-6-13-4-2-3-5-14(13)11-15/h2-11H,1H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15345 (Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...) Show SMILES Clc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2NO/c18-14-7-8-16(15(19)10-14)20-17(21)13-6-5-11-3-1-2-4-12(11)9-13/h1-10H,(H,20,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM14710 (ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...) Show SMILES Cc1cc(Br)ccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H14BrNO/c1-12-10-16(19)8-9-17(12)20-18(21)15-7-6-13-4-2-3-5-14(13)11-15/h2-11H,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Protein Wnt-2 (Mus musculus (Mouse))	BDBM50294835 (4-((1S,2S,6R,7R)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...) Show SMILES Oc1c2[C@H]3C[C@H](C=C3)c2c(O)n1-c1ccc(cc1)C(=O)Nc1cccc2cccnc12 |r,c:6| Show InChI InChI=1S/C25H19N3O3/c29-23(27-19-5-1-3-14-4-2-12-26-22(14)19)15-8-10-18(11-9-15)28-24(30)20-16-6-7-17(13-16)21(20)25(28)31/h1-12,16-17,30-31H,13H2,(H,27,29)/t16-,17+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Inhibition assay of Wnt response treated with exogenously supplied of Wnt protein ('exogenous Wnt' test)				Nat Chem Biol 5: 100-7 (2009) Article DOI: 10.1038/nchembio.137 BindingDB Entry DOI: 10.7270/Q2HX1B20
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15349 (Asinex compound no. 4 | N-(3-bromophenyl)-2-methyl...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrN2O3/c1-9-12(6-3-7-13(9)17(19)20)14(18)16-11-5-2-4-10(15)8-11/h2-8H,1H3,(H,16,18)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15345 (Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...) Show SMILES Clc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2NO/c18-14-7-8-16(15(19)10-14)20-17(21)13-6-5-11-3-1-2-4-12(11)9-13/h1-10H,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15354 (Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15353 (2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | Ch...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H14N2O3/c1-12-14(9-5-11-17(12)20(22)23)18(21)19-16-10-4-7-13-6-2-3-8-15(13)16/h2-11H,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434232 (CHEMBL2385514) Show SMILES OC(=O)c1cc(nc2ccc(Cl)cc12)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C22H14ClNO3/c23-15-8-11-20-18(12-15)19(22(25)26)13-21(24-20)14-6-9-17(10-7-14)27-16-4-2-1-3-5-16/h1-13H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15350 (ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H10ClFN2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-12(16)11(15)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15357 (3-(2-methoxyphenyl)-1-naphthalen-1-ylurea | ChemBr...) Show SMILES COc1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c1-22-17-12-5-4-10-16(17)20-18(21)19-15-11-6-8-13-7-2-3-9-14(13)15/h2-12H,1H3,(H2,19,20,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15357 (3-(2-methoxyphenyl)-1-naphthalen-1-ylurea | ChemBr...) Show SMILES COc1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c1-22-17-12-5-4-10-16(17)20-18(21)19-15-11-6-8-13-7-2-3-9-14(13)15/h2-12H,1H3,(H2,19,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434236 (CHEMBL2385715) Show SMILES CCCOc1ccc(cc1)-c1cc(C(O)=O)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C19H16ClNO3/c1-2-9-24-14-6-3-12(4-7-14)18-11-16(19(22)23)15-10-13(20)5-8-17(15)21-18/h3-8,10-11H,2,9H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15352 (ChemBridge compound no. 7 | N-(3,4-difluorophenyl)...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C14H10F2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15348 (ChemBridge compound no. 3 | N-(2-fluorophenyl)naph...) Show SMILES Fc1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12FNO/c18-15-7-3-4-8-16(15)19-17(20)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434235 (CHEMBL2385719) Show SMILES OC(=O)c1cc(nc2ccc(Cl)cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C17H9ClF3NO3/c18-10-3-6-14-12(7-10)13(16(23)24)8-15(22-14)9-1-4-11(5-2-9)25-17(19,20)21/h1-8H,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15356 (1-naphthalen-1-yl-3-[2-(trifluoromethyl)phenyl]ure...) Show SMILES FC(F)(F)c1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13F3N2O/c19-18(20,21)14-9-3-4-10-16(14)23-17(24)22-15-11-5-7-12-6-1-2-8-13(12)15/h1-11H,(H2,22,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15356 (1-naphthalen-1-yl-3-[2-(trifluoromethyl)phenyl]ure...) Show SMILES FC(F)(F)c1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13F3N2O/c19-18(20,21)14-9-3-4-10-16(14)23-17(24)22-15-11-5-7-12-6-1-2-8-13(12)15/h1-11H,(H2,22,23,24)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM14711 (Asinex compound no. 6 | N-(3,5-Dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-12(3-2-4-13(8)18(20)21)14(19)17-11-6-9(15)5-10(16)7-11/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15348 (ChemBridge compound no. 3 | N-(2-fluorophenyl)naph...) Show SMILES Fc1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12FNO/c18-15-7-3-4-8-16(15)19-17(20)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15353 (2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | Ch...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H14N2O3/c1-12-14(9-5-11-17(12)20(22)23)18(21)19-16-10-4-7-13-6-2-3-8-15(13)16/h2-11H,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15350 (ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H10ClFN2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-12(16)11(15)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15358 (3-(4-chlorophenyl)-1-quinolin-8-ylurea | Asinex co...) Show SMILES Clc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 Show InChI InChI=1S/C16H12ClN3O/c17-12-6-8-13(9-7-12)19-16(21)20-14-5-1-3-11-4-2-10-18-15(11)14/h1-10H,(H2,19,20,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15352 (ChemBridge compound no. 7 | N-(3,4-difluorophenyl)...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C14H10F2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15349 (Asinex compound no. 4 | N-(3-bromophenyl)-2-methyl...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrN2O3/c1-9-12(6-3-7-13(9)17(19)20)14(18)16-11-5-2-4-10(15)8-11/h2-8H,1H3,(H,16,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434234 (CHEMBL2385720) Show SMILES OC(=O)c1cc(nc2ccc(Cl)cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C16H9ClFNO2/c17-10-3-6-14-12(7-10)13(16(20)21)8-15(19-14)9-1-4-11(18)5-2-9/h1-8H,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15358 (3-(4-chlorophenyl)-1-quinolin-8-ylurea | Asinex co...) Show SMILES Clc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 Show InChI InChI=1S/C16H12ClN3O/c17-12-6-8-13(9-7-12)19-16(21)20-14-5-1-3-11-4-2-10-18-15(11)14/h1-10H,(H2,19,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15354 (Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50434233 (CHEMBL2385721) Show SMILES Cc1ccc(cc1)-c1cc(C(O)=O)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C17H12ClNO2/c1-10-2-4-11(5-3-10)16-9-14(17(20)21)13-8-12(18)6-7-15(13)19-16/h2-9H,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of human DHODH				ACS Med Chem Lett 4: 517-521 (2013) Article DOI: 10.1021/ml300464h BindingDB Entry DOI: 10.7270/Q26H4JS3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15348 (ChemBridge compound no. 3 | N-(2-fluorophenyl)naph...) Show SMILES Fc1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12FNO/c18-15-7-3-4-8-16(15)19-17(20)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15345 (Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...) Show SMILES Clc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2NO/c18-14-7-8-16(15(19)10-14)20-17(21)13-6-5-11-3-1-2-4-12(11)9-13/h1-10H,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15345 (Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...) Show SMILES Clc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2NO/c18-14-7-8-16(15(19)10-14)20-17(21)13-6-5-11-3-1-2-4-12(11)9-13/h1-10H,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15354 (Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15354 (Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15353 (2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | Ch...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H14N2O3/c1-12-14(9-5-11-17(12)20(22)23)18(21)19-16-10-4-7-13-6-2-3-8-15(13)16/h2-11H,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15349 (Asinex compound no. 4 | N-(3-bromophenyl)-2-methyl...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrN2O3/c1-9-12(6-3-7-13(9)17(19)20)14(18)16-11-5-2-4-10(15)8-11/h2-8H,1H3,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15357 (3-(2-methoxyphenyl)-1-naphthalen-1-ylurea | ChemBr...) Show SMILES COc1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c1-22-17-12-5-4-10-16(17)20-18(21)19-15-11-6-8-13-7-2-3-9-14(13)15/h2-12H,1H3,(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15350 (ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H10ClFN2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-12(16)11(15)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15358 (3-(4-chlorophenyl)-1-quinolin-8-ylurea | Asinex co...) Show SMILES Clc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 Show InChI InChI=1S/C16H12ClN3O/c17-12-6-8-13(9-7-12)19-16(21)20-14-5-1-3-11-4-2-10-18-15(11)14/h1-10H,(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair

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