Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496737 (CHEMBL3220783) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50026326 (CHEMBL3305928) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496738 (CHEMBL3220785) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli O127:H6 (strain E2348/69 / EPEC)) | BDBM50026326 (CHEMBL3305928) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of Escherichia coli DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli O127:H6 (strain E2348/69 / EPEC)) | BDBM50026312 (CHEMBL3306297) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of Escherichia coli DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496736 (CHEMBL3220784) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli O127:H6 (strain E2348/69 / EPEC)) | BDBM50026348 (CHEMBL3359030) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of Escherichia coli DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Haemophilus influenzae (strain 86-028NP)) | BDBM50026349 (KETOCLOMAZONE) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of Haemophilus influenzae DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496741 (CHEMBL3220786) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.58E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM108228 (1‐nitroso‐2‐naphthol (Substrate ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 4.22E+5 | -20.0 | 1.07E+6 | n/a | n/a | n/a | n/a | 8.0 | 37 |
The Johns Hopkins University School of Medicine, 725 North Wolfe St, Baltimore, MD 21205, USA | Assay Description Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate... | Chembiochem 14: 1309-15 (2013) Article DOI: 10.1002/cbic.201300187 BindingDB Entry DOI: 10.7270/Q2J101T3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496739 (CHEMBL3220787) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50496740 (CHEMBL3220788) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri... | Medchemcomm 3: 65-67 (2012) Article DOI: 10.1039/c1md00233c BindingDB Entry DOI: 10.7270/Q2P55RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic (Arabidopsis thaliana) | BDBM50026349 (KETOCLOMAZONE) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
BASF-SE Curated by ChEMBL | Assay Description Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ... | Pest Manag Sci 69: 559-63 (2013) Article DOI: 10.1002/ps.3479 BindingDB Entry DOI: 10.7270/Q2DZ0C67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Haemophilus influenzae (strain 86-028NP)) | BDBM50026350 (CHEMBL3359031) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of Haemophilus influenzae DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Haemophilus influenzae (strain 86-028NP)) | BDBM50026351 (CHEMBL3359032) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Groningen Curated by ChEMBL | Assay Description Inhibition of Haemophilus influenzae DXS | J Med Chem 57: 9740-63 (2014) Article DOI: 10.1021/jm5010978 BindingDB Entry DOI: 10.7270/Q29K4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264033 (3-(4-fluorophenyl)-5-(4-methoxyphenyl)-2-methylpyr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263972 (3-(4-chlorophenyl)-5-(4-methoxyphenyl)-2-methylpyr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263925 (5-benzyl-3-(4-chlorophenyl)-2-(trifluoromethyl)pyr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264091 (2-methyl-3,5-diphenyl-6-propylpyrazolo[1,5-a]pyrim...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264090 (2-methyl-5-(naphthalen-2-yl)-3-phenylpyrazolo[1,5-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264092 (3-(4-chlorophenyl)-2-ethyl-5-(4-methoxyphenyl)pyra...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM58242 (3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)-1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM51305 (3,5-diphenyl-2-(trifluoromethyl)-1H-pyrazolo[1,5-a...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264035 (2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7(4H...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic (Arabidopsis thaliana) | BDBM50488590 (CHEMBL526942 | TCMDC-125235) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
BASF-SE Curated by ChEMBL | Assay Description Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ... | Pest Manag Sci 69: 559-63 (2013) Article DOI: 10.1002/ps.3479 BindingDB Entry DOI: 10.7270/Q2DZ0C67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic (Arabidopsis thaliana) | BDBM50488588 (CHEMBL2289498) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
BASF-SE Curated by ChEMBL | Assay Description Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ... | Pest Manag Sci 69: 559-63 (2013) Article DOI: 10.1002/ps.3479 BindingDB Entry DOI: 10.7270/Q2DZ0C67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263971 (3-(4-chlorophenyl)-2-methyl-5-phenylpyrazolo[1,5-a...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264037 (3-(4-chlorophenyl)-5-((4-chlorophenylthio)methyl)-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263970 (3,5-bis(4-methoxyphenyl)-2-methylpyrazolo[1,5-a]py...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic (Arabidopsis thaliana) | BDBM50488589 (CHEMBL2289496) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
BASF-SE Curated by ChEMBL | Assay Description Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ... | Pest Manag Sci 69: 559-63 (2013) Article DOI: 10.1002/ps.3479 BindingDB Entry DOI: 10.7270/Q2DZ0C67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264034 (3-(4-bromophenyl)-5-(2-methoxyphenyl)-2-methylpyra...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264036 (3-(4-chlorophenyl)-2-methyl-5-((1-phenyl-1H-tetraz...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic (Arabidopsis thaliana) | BDBM50488595 (CHEMBL2289497) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
BASF-SE Curated by ChEMBL | Assay Description Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ... | Pest Manag Sci 69: 559-63 (2013) Article DOI: 10.1002/ps.3479 BindingDB Entry DOI: 10.7270/Q2DZ0C67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264088 (5-((4-chlorophenylthio)methyl)-2-methyl-3-phenylpy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263876 (5-benzyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263927 (CHEMBL491398 | methyl 2-(3-(4-bromophenyl)-7-oxo-2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263969 (3-(4-methoxyphenyl)-2-methyl-5-phenylpyrazolo[1,5-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263929 (3-(4-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263817 (5-benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.14E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263344 (3,5-Bis-(4-chloro-phenyl)-7-trifluoromethyl-pyrazo...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50264089 (3-(4-chlorophenyl)-5-(methoxymethyl)-2-methylpyraz...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM40457 (3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(tr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263928 (3-(4-bromophenyl)-5-methyl-2-(trifluoromethyl)pyra...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263873 (3-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263874 (CHEMBL1608283 | ethyl 2-(5-methyl-7-oxo-3-phenyl-4...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263875 (5-(chloromethyl)-3-phenylpyrazolo[1,5-a]pyrimidin-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263872 (3-(4-chlorophenyl)-5-(methoxymethyl)pyrazolo[1,5-a...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis) | BDBM50263345 (3-(3-Bromo-phenyl)-5,7-diphenyl-pyrazolo[1,5-a]pyr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Bioorg Med Chem Lett 18: 5320-3 (2008) Article DOI: 10.1016/j.bmcl.2008.08.034 BindingDB Entry DOI: 10.7270/Q2TX3F71 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM50065935 (CHEMBL98797 | NOB | Nitrosobenzene (Substrate 1) |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.08E+5 | n/a | n/a | n/a | n/a | 8.0 | 37 |
The Johns Hopkins University School of Medicine, 725 North Wolfe St, Baltimore, MD 21205, USA | Assay Description Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate... | Chembiochem 14: 1309-15 (2013) Article DOI: 10.1002/cbic.201300187 BindingDB Entry DOI: 10.7270/Q2J101T3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1-deoxy-D-xylulose-5-phosphate synthase (Escherichia coli K-12 (Enterobacteria)) | BDBM108226 (1‐methyl‐2‐nitrosobenzene (Subst...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.91E+5 | n/a | n/a | n/a | n/a | 8.0 | 37 |
The Johns Hopkins University School of Medicine, 725 North Wolfe St, Baltimore, MD 21205, USA | Assay Description Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate... | Chembiochem 14: 1309-15 (2013) Article DOI: 10.1002/cbic.201300187 BindingDB Entry DOI: 10.7270/Q2J101T3 | |||||||||||
More data for this Ligand-Target Pair |
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