Compile Data Set for Download or QSAR

Found 39 hits with Last Name = 'conklin' and Initial = 'rl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50161093 ((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...) Show SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1cccc(Cl)c1C#N |r| Show InChI InChI=1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50161093 ((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...) Show SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1cccc(Cl)c1C#N |r| Show InChI InChI=1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166511 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES CC(C)c1c(C)nc(-c2ccccc2O)n(CCc2cccc(F)c2)c1=O Show InChI InChI=1S/C22H23FN2O2/c1-14(2)20-15(3)24-21(18-9-4-5-10-19(18)26)25(22(20)27)12-11-16-7-6-8-17(23)13-16/h4-10,13-14,26H,11-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166504 (5-Ethyl-3-[2-(2-fluoro-phenyl)-ethyl]-2-(2-hydroxy...) Show SMILES CCc1c(C)nc(-c2ccccc2O)n(CCc2ccccc2F)c1=O Show InChI InChI=1S/C21H21FN2O2/c1-3-16-14(2)23-20(17-9-5-7-11-19(17)25)24(21(16)26)13-12-15-8-4-6-10-18(15)22/h4-11,25H,3,12-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166510 (5-Ethyl-2-(2-hydroxy-phenyl)-6-methyl-3-phenethyl-...) Show SMILES CCc1c(C)nc(-c2ccccc2O)n(CCc2ccccc2)c1=O Show InChI InChI=1S/C21H22N2O2/c1-3-17-15(2)22-20(18-11-7-8-12-19(18)24)23(21(17)25)14-13-16-9-5-4-6-10-16/h4-12,24H,3,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166517 (5-Cyclopropyl-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-h...) Show SMILES Cc1nc(-c2ccccc2O)n(CCc2cccc(F)c2)c(=O)c1C1CC1 Show InChI InChI=1S/C22H21FN2O2/c1-14-20(16-9-10-16)22(27)25(12-11-15-5-4-6-17(23)13-15)21(24-14)18-7-2-3-8-19(18)26/h2-8,13,16,26H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166503 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES CCCc1c(C)nc(-c2ccccc2O)n(CCc2cccc(F)c2)c1=O Show InChI InChI=1S/C22H23FN2O2/c1-3-7-18-15(2)24-21(19-10-4-5-11-20(19)26)25(22(18)27)13-12-16-8-6-9-17(23)14-16/h4-6,8-11,14,26H,3,7,12-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166507 (2-(2-Hydroxy-phenyl)-3-phenethyl-4a,5,6,7,8,8a-hex...) Show SMILES Oc1ccccc1C1=NC2CCCCC2C(=O)N1CCc1ccccc1 |t:8| Show InChI InChI=1S/C22H24N2O2/c25-20-13-7-5-11-18(20)21-23-19-12-6-4-10-17(19)22(26)24(21)15-14-16-8-2-1-3-9-16/h1-3,5,7-9,11,13,17,19,25H,4,6,10,12,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166505 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Oc1ccccc1C1=NC2CCCCC2C(=O)N1CCc1cccc(F)c1 |t:8| Show InChI InChI=1S/C22H23FN2O2/c23-16-7-5-6-15(14-16)12-13-25-21(18-9-2-4-11-20(18)26)24-19-10-3-1-8-17(19)22(25)27/h2,4-7,9,11,14,17,19,26H,1,3,8,10,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166512 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Cc1nc(-c2ccccc2O)n(CCc2cccc(F)c2)c(=O)c1C Show InChI InChI=1S/C20H19FN2O2/c1-13-14(2)22-19(17-8-3-4-9-18(17)24)23(20(13)25)11-10-15-6-5-7-16(21)12-15/h3-9,12,24H,10-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162536 (6-Fluoro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...) Show SMILES Oc1ccccc1-c1nc2ccc(F)cc2c(=O)n1CCc1cccc(F)c1 Show InChI InChI=1S/C22H16F2N2O2/c23-15-5-3-4-14(12-15)10-11-26-21(17-6-1-2-7-20(17)27)25-19-9-8-16(24)13-18(19)22(26)28/h1-9,12-13,27H,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166508 (2-(2-Hydroxy-phenyl)-3-phenethyl-3,4a,5,6,7,7a-hex...) Show SMILES Oc1ccccc1C1=NC2CCCC2C(=O)N1CCc1ccccc1 |t:8| Show InChI InChI=1S/C21H22N2O2/c24-19-12-5-4-9-17(19)20-22-18-11-6-10-16(18)21(25)23(20)14-13-15-7-2-1-3-8-15/h1-5,7-9,12,16,18,24H,6,10-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166514 (2-(2-Hydroxy-phenyl)-5,6-dimethyl-3-phenethyl-3H-p...) Show SMILES Cc1nc(-c2ccccc2O)n(CCc2ccccc2)c(=O)c1C Show InChI InChI=1S/C20H20N2O2/c1-14-15(2)21-19(17-10-6-7-11-18(17)23)22(20(14)24)13-12-16-8-4-3-5-9-16/h3-11,23H,12-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166509 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Oc1ccccc1C1=NC2CCCC2C(=O)N1CCc1cccc(F)c1 |t:8| Show InChI InChI=1S/C21H21FN2O2/c22-15-6-3-5-14(13-15)11-12-24-20(17-7-1-2-10-19(17)25)23-18-9-4-8-16(18)21(24)26/h1-3,5-7,10,13,16,18,25H,4,8-9,11-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162537 (6-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...) Show SMILES Oc1ccccc1-c1nc2ccc(F)cc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H17FN2O2/c23-16-10-11-19-18(14-16)22(27)25(13-12-15-6-2-1-3-7-15)21(24-19)17-8-4-5-9-20(17)26/h1-11,14,26H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162538 (2-(2-Hydroxy-phenyl)-5-methyl-3-phenethyl-3H-quina...) Show SMILES Cc1cccc2nc(-c3ccccc3O)n(CCc3ccccc3)c(=O)c12 Show InChI InChI=1S/C23H20N2O2/c1-16-8-7-12-19-21(16)23(27)25(15-14-17-9-3-2-4-10-17)22(24-19)18-11-5-6-13-20(18)26/h2-13,26H,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162547 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Cc1cccc2nc(-c3ccccc3O)n(CCc3cccc(F)c3)c(=O)c12 Show InChI InChI=1S/C23H19FN2O2/c1-15-6-4-10-19-21(15)23(28)26(13-12-16-7-5-8-17(24)14-16)22(25-19)18-9-2-3-11-20(18)27/h2-11,14,27H,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162554 (2-(2-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Oc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H18N2O2/c25-20-13-7-5-11-18(20)21-23-19-12-6-4-10-17(19)22(26)24(21)15-14-16-8-2-1-3-9-16/h1-13,25H,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162553 (6-Chloro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...) Show SMILES Oc1ccccc1-c1nc2ccc(Cl)cc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H17ClN2O2/c23-16-10-11-19-18(14-16)22(27)25(13-12-15-6-2-1-3-7-15)21(24-19)17-8-4-5-9-20(17)26/h1-11,14,26H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162539 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Cc1ccc2nc(-c3ccccc3O)n(CCc3cccc(F)c3)c(=O)c2c1 Show InChI InChI=1S/C23H19FN2O2/c1-15-9-10-20-19(13-15)23(28)26(12-11-16-5-4-6-17(24)14-16)22(25-20)18-7-2-3-8-21(18)27/h2-10,13-14,27H,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162552 (7-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...) Show SMILES Oc1ccccc1-c1nc2cc(F)ccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H17FN2O2/c23-16-10-11-17-19(14-16)24-21(18-8-4-5-9-20(18)26)25(22(17)27)13-12-15-6-2-1-3-7-15/h1-11,14,26H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162545 (2-(2-Hydroxy-phenyl)-8-methyl-3-phenethyl-3H-quina...) Show SMILES Cc1cccc2c1nc(-c1ccccc1O)n(CCc1ccccc1)c2=O Show InChI InChI=1S/C23H20N2O2/c1-16-8-7-12-19-21(16)24-22(18-11-5-6-13-20(18)26)25(23(19)27)15-14-17-9-3-2-4-10-17/h2-13,26H,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162555 (3-[2-(3-Chloro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Oc1ccccc1-c1nc2ccccc2c(=O)n1CCc1cccc(Cl)c1 Show InChI InChI=1S/C22H17ClN2O2/c23-16-7-5-6-15(14-16)12-13-25-21(18-9-2-4-11-20(18)26)24-19-10-3-1-8-17(19)22(25)27/h1-11,14,26H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166516 (2-(2-Hydroxy-phenyl)-5-methyl-3-phenethyl-6-triflu...) Show SMILES Cc1c(nc(-c2ccccc2O)n(CCc2ccccc2)c1=O)C(F)(F)F Show InChI InChI=1S/C20H17F3N2O2/c1-13-17(20(21,22)23)24-18(15-9-5-6-10-16(15)26)25(19(13)27)12-11-14-7-3-2-4-8-14/h2-10,26H,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166506 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Cc1cc(=O)n(CCc2cccc(F)c2)c(n1)-c1ccccc1O Show InChI InChI=1S/C19H17FN2O2/c1-13-11-18(24)22(10-9-14-5-4-6-15(20)12-14)19(21-13)16-7-2-3-8-17(16)23/h2-8,11-12,23H,9-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162549 (7-Chloro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...) Show SMILES Oc1ccccc1-c1nc2cc(Cl)ccc2c(=O)n1CCc1cccc(F)c1 Show InChI InChI=1S/C22H16ClFN2O2/c23-15-8-9-17-19(13-15)25-21(18-6-1-2-7-20(18)27)26(22(17)28)11-10-14-4-3-5-16(24)12-14/h1-9,12-13,27H,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162546 (2-(2,5-Dihydroxy-phenyl)-3-phenethyl-3H-quinazolin...) Show SMILES Oc1ccc(O)c(c1)-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H18N2O3/c25-16-10-11-20(26)18(14-16)21-23-19-9-5-4-8-17(19)22(27)24(21)13-12-15-6-2-1-3-7-15/h1-11,14,25-26H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166515 (3-[2-(2-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Cc1cc(=O)n(CCc2ccccc2F)c(n1)-c1ccccc1O Show InChI InChI=1S/C19H17FN2O2/c1-13-12-18(24)22(11-10-14-6-2-4-8-16(14)20)19(21-13)15-7-3-5-9-17(15)23/h2-9,12,23H,10-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50166513 (2-(2-Hydroxy-phenyl)-6-methyl-3-phenethyl-3H-pyrim...) Show SMILES Cc1cc(=O)n(CCc2ccccc2)c(n1)-c1ccccc1O Show InChI InChI=1S/C19H18N2O2/c1-14-13-18(23)21(12-11-15-7-3-2-4-8-15)19(20-14)16-9-5-6-10-17(16)22/h2-10,13,22H,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162535 (2-(3-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Oc1cccc(c1)-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H18N2O2/c25-18-10-6-9-17(15-18)21-23-20-12-5-4-11-19(20)22(26)24(21)14-13-16-7-2-1-3-8-16/h1-12,15,25H,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162542 (2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...) Show SMILES O=c1n(CCc2ccccc2)c(nc2ccccc12)-c1ccco1 Show InChI InChI=1S/C20H16N2O2/c23-20-16-9-4-5-10-17(16)21-19(18-11-6-14-24-18)22(20)13-12-15-7-2-1-3-8-15/h1-11,14H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162542 (2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...) Show SMILES O=c1n(CCc2ccccc2)c(nc2ccccc12)-c1ccco1 Show InChI InChI=1S/C20H16N2O2/c23-20-16-9-4-5-10-17(16)21-19(18-11-6-14-24-18)22(20)13-12-15-7-2-1-3-8-15/h1-11,14H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162540 (3-Phenethyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1...) Show SMILES O=c1n(CCc2ccccc2)c(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C22H18N2O/c25-22-19-13-7-8-14-20(19)23-21(18-11-5-2-6-12-18)24(22)16-15-17-9-3-1-4-10-17/h1-14H,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162550 (2-(3-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES COc1cccc(c1)-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C23H20N2O2/c1-27-19-11-7-10-18(16-19)22-24-21-13-6-5-12-20(21)23(26)25(22)15-14-17-8-3-2-4-9-17/h2-13,16H,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162544 (2-(2-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES COc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C23H20N2O2/c1-27-21-14-8-6-12-19(21)22-24-20-13-7-5-11-18(20)23(26)25(22)16-15-17-9-3-2-4-10-17/h2-14H,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162543 (2-(3-Fluoro-phenyl)-3-phenethyl-3H-quinazolin-4-on...) Show SMILES Fc1cccc(c1)-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H17FN2O/c23-18-10-6-9-17(15-18)21-24-20-12-5-4-11-19(20)22(26)25(21)14-13-16-7-2-1-3-8-16/h1-12,15H,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162548 (2-(4-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES COc1ccc(cc1)-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C23H20N2O2/c1-27-19-13-11-18(12-14-19)22-24-21-10-6-5-9-20(21)23(26)25(22)16-15-17-7-3-2-4-8-17/h2-14H,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162551 (2-(2-Fluoro-phenyl)-3-phenethyl-3H-quinazolin-4-on...) Show SMILES Fc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H17FN2O/c23-19-12-6-4-10-17(19)21-24-20-13-7-5-11-18(20)22(26)25(21)15-14-16-8-2-1-3-9-16/h1-13H,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162541 (2-(4-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H18N2O2/c25-18-12-10-17(11-13-18)21-23-20-9-5-4-8-19(20)22(26)24(21)15-14-16-6-2-1-3-7-16/h1-13,25H,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair