Compile Data Set for Download or QSAR

Found 63 hits Enz. Inhib. hit(s) with all data for entry = 992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301953 (3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1ccc2[nH]cc(CCCN3CCN(CC3)c3nc(OC)cc(OC)n3)c2c1 Show InChI InChI=1S/C22H29N5O3/c1-28-17-6-7-19-18(13-17)16(15-23-19)5-4-8-26-9-11-27(12-10-26)22-24-20(29-2)14-21(25-22)30-3/h6-7,13-15,23H,4-5,8-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301980 (3-(3-(4-(4-(Trifluoromethyl)pyrimidin-2-yl)piperaz...) Show SMILES FC(F)(F)c1ccnc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)[N+]#[C-])CC1 Show InChI InChI=1S/C21H21F3N6/c1-25-16-4-5-18-17(13-16)15(14-27-18)3-2-8-29-9-11-30(12-10-29)20-26-7-6-19(28-20)21(22,23)24/h4-7,13-14,27H,2-3,8-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301982 (Ethyl 2-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piper...) Show SMILES CCOC(=O)c1sc(nc1C)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C22H27FN4O2S/c1-3-29-21(28)20-15(2)25-22(30-20)27-11-9-26(10-12-27)8-4-5-16-14-24-19-7-6-17(23)13-18(16)19/h6-7,13-14,24H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301963 (3-(3-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES COc1ccc2[nH]cc(CCCN3CCN(CC3)c3nc(C)cc(C)n3)c2c1 Show InChI InChI=1S/C22H29N5O/c1-16-13-17(2)25-22(24-16)27-11-9-26(10-12-27)8-4-5-18-15-23-21-7-6-19(28-3)14-20(18)21/h6-7,13-15,23H,4-5,8-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301984 (Ethyl 2-(4-(3-(5-cyano-1H-indol-3-yl)propyl)pipera...) Show SMILES CCOC(=O)c1sc(nc1C)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C23H27N5O2S/c1-3-30-22(29)21-16(2)26-23(31-21)28-11-9-27(10-12-28)8-4-5-18-15-25-20-7-6-17(14-24)13-19(18)20/h6-7,13,15,25H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301967 (3-(4-(4-(4-Methoxy-6-methylpyrimidin-2-yl)piperazi...) Show SMILES COc1cc(C)nc(n1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C23H28N6O/c1-17-13-22(30-2)27-23(26-17)29-11-9-28(10-12-29)8-4-3-5-19-16-25-21-7-6-18(15-24)14-20(19)21/h6-7,13-14,16,25H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301978 (3-(4-(4-(4-(Trifluoromethyl)pyrimidin-2-yl)piperaz...) Show SMILES FC(F)(F)c1ccnc(n1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H23F3N6/c23-22(24,25)20-6-7-27-21(29-20)31-11-9-30(10-12-31)8-2-1-3-17-15-28-19-5-4-16(14-26)13-18(17)19/h4-7,13,15,28H,1-3,8-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301964 (5-Chloro-3-(3-(4-(4,6-dimethylpyrimidin-2-yl)piper...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCc2c[nH]c3ccc(Cl)cc23)CC1 Show InChI InChI=1S/C21H26ClN5/c1-15-12-16(2)25-21(24-15)27-10-8-26(9-11-27)7-3-4-17-14-23-20-6-5-18(22)13-19(17)20/h5-6,12-14,23H,3-4,7-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301983 (Ethyl 2-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperaz...) Show SMILES CCOC(=O)c1sc(nc1C)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C24H29N5O2S/c1-3-31-23(30)22-17(2)27-24(32-22)29-12-10-28(11-13-29)9-5-4-6-19-16-26-21-8-7-18(15-25)14-20(19)21/h7-8,14,16,26H,3-6,9-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301979 (5-Fluoro-3-(3-(4-(4-(trifluoromethyl)pyrimidin-2-y...) Show SMILES Fc1ccc2[nH]cc(CCCN3CCN(CC3)c3nccc(n3)C(F)(F)F)c2c1 Show InChI InChI=1S/C20H21F4N5/c21-15-3-4-17-16(12-15)14(13-26-17)2-1-7-28-8-10-29(11-9-28)19-25-6-5-18(27-19)20(22,23)24/h3-6,12-13,26H,1-2,7-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301958 (3-(4-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3nc(C)cc(C)n3)c2c1 Show InChI InChI=1S/C23H31N5O/c1-17-14-18(2)26-23(25-17)28-12-10-27(11-13-28)9-5-4-6-19-16-24-22-8-7-20(29-3)15-21(19)22/h7-8,14-16,24H,4-6,9-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301957 (3-(4-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C22H29N5/c1-17-15-18(2)25-22(24-17)27-13-11-26(12-14-27)10-6-5-7-19-16-23-21-9-4-3-8-20(19)21/h3-4,8-9,15-16,23H,5-7,10-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301949 (5-Chloro-3-(4-(4-(4,6-dimethoxypyrimidin-2-yl)pipe...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCCc2c[nH]c3ccc(Cl)cc23)CC1 Show InChI InChI=1S/C22H28ClN5O2/c1-29-20-14-21(30-2)26-22(25-20)28-11-9-27(10-12-28)8-4-3-5-16-15-24-19-7-6-17(23)13-18(16)19/h6-7,13-15,24H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301966 (3-(3-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H26N6/c1-16-12-17(2)26-22(25-16)28-10-8-27(9-11-28)7-3-4-19-15-24-21-6-5-18(14-23)13-20(19)21/h5-6,12-13,15,24H,3-4,7-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301956 (3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H26N6O2/c1-29-20-13-21(30-2)26-22(25-20)28-10-8-27(9-11-28)7-3-4-17-15-24-19-6-5-16(14-23)12-18(17)19/h5-6,12-13,15,24H,3-4,7-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301965 (3-(3-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C21H26FN5/c1-15-12-16(2)25-21(24-15)27-10-8-26(9-11-27)7-3-4-17-14-23-20-6-5-18(22)13-19(17)20/h5-6,12-14,23H,3-4,7-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301948 (3-(4-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3nc(OC)cc(OC)n3)c2c1 Show InChI InChI=1S/C23H31N5O3/c1-29-18-7-8-20-19(14-18)17(16-24-20)6-4-5-9-27-10-12-28(13-11-27)23-25-21(30-2)15-22(26-23)31-3/h7-8,14-16,24H,4-6,9-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301968 (3-(3-(4-(4-Methoxy-6-methylpyrimidin-2-yl)piperazi...) Show SMILES COc1cc(C)nc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)[N+]#[C-])CC1 Show InChI InChI=1S/C22H26N6O/c1-16-13-21(29-3)26-22(25-16)28-11-9-27(10-12-28)8-4-5-17-15-24-20-7-6-18(23-2)14-19(17)20/h6-7,13-15,24H,4-5,8-12H2,1,3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301960 (3-(4-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C22H28FN5/c1-16-13-17(2)26-22(25-16)28-11-9-27(10-12-28)8-4-3-5-18-15-24-21-7-6-19(23)14-20(18)21/h6-7,13-15,24H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301959 (5-Chloro-3-(4-(4-(4,6-dimethylpyrimidin-2-yl)piper...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCCc2c[nH]c3ccc(Cl)cc23)CC1 Show InChI InChI=1S/C22H28ClN5/c1-16-13-17(2)26-22(25-16)28-11-9-27(10-12-28)8-4-3-5-18-15-24-21-7-6-19(23)14-20(18)21/h6-7,13-15,24H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301977 (5-Fluoro-3-(4-(4-(4-(trifluoromethyl)pyrimidin-2-y...) Show SMILES Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3nccc(n3)C(F)(F)F)c2c1 Show InChI InChI=1S/C21H23F4N5/c22-16-4-5-18-17(13-16)15(14-27-18)3-1-2-8-29-9-11-30(12-10-29)20-26-7-6-19(28-20)21(23,24)25/h4-7,13-14,27H,1-3,8-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301954 (5-Chloro-3-(3-(4-(4,6-dimethoxypyrimidin-2-yl)pipe...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCc2c[nH]c3ccc(Cl)cc23)CC1 Show InChI InChI=1S/C21H26ClN5O2/c1-28-19-13-20(29-2)25-21(24-19)27-10-8-26(9-11-27)7-3-4-15-14-23-18-6-5-16(22)12-17(15)18/h5-6,12-14,23H,3-4,7-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301951 (3-(4-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C23H28N6O2/c1-30-21-14-22(31-2)27-23(26-21)29-11-9-28(10-12-29)8-4-3-5-18-16-25-20-7-6-17(15-24)13-19(18)20/h6-7,13-14,16,25H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301992 (2-(4-(3-(5-Cyano-1H-indol-3-yl)propyl)piperazin-1-...) Show SMILES Cc1nc(sc1C#N)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C21H22N6S/c1-15-20(13-23)28-21(25-15)27-9-7-26(8-10-27)6-2-3-17-14-24-19-5-4-16(12-22)11-18(17)19/h4-5,11,14,24H,2-3,6-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301950 (3-(4-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C22H28FN5O2/c1-29-20-14-21(30-2)26-22(25-20)28-11-9-27(10-12-28)8-4-3-5-16-15-24-19-7-6-17(23)13-18(16)19/h6-7,13-15,24H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301961 (3-(4-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C23H28N6/c1-17-13-18(2)27-23(26-17)29-11-9-28(10-12-29)8-4-3-5-20-16-25-22-7-6-19(15-24)14-21(20)22/h6-7,13-14,16,25H,3-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301947 (3-(4-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C22H29N5O2/c1-28-20-15-21(29-2)25-22(24-20)27-13-11-26(12-14-27)10-6-5-7-17-16-23-19-9-4-3-8-18(17)19/h3-4,8-9,15-16,23H,5-7,10-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301955 (3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C21H26FN5O2/c1-28-19-13-20(29-2)25-21(24-19)27-10-8-26(9-11-27)7-3-4-15-14-23-18-6-5-16(22)12-17(15)18/h5-6,12-14,23H,3-4,7-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301988 (2-(4-(3-(5-Cyano-1H-indol-3-yl)propyl)piperazin-1-...) Show SMILES Cc1nc(sc1C(N)=O)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C21H24N6OS/c1-14-19(20(23)28)29-21(25-14)27-9-7-26(8-10-27)6-2-3-16-13-24-18-5-4-15(12-22)11-17(16)18/h4-5,11,13,24H,2-3,6-10H2,1H3,(H2,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301971 (2-(4-(3-(5-Fluoro-1H-indol-3-yl)propyl)piperazin-1...) Show SMILES Fc1ccc2[nH]cc(CCCN3CCN(CC3)c3nccc(n3)C#N)c2c1 Show InChI InChI=1S/C20H21FN6/c21-16-3-4-19-18(12-16)15(14-24-19)2-1-7-26-8-10-27(11-9-26)20-23-6-5-17(13-22)25-20/h3-6,12,14,24H,1-2,7-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301962 (3-(3-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C21H27N5/c1-16-14-17(2)24-21(23-16)26-12-10-25(11-13-26)9-5-6-18-15-22-20-8-4-3-7-19(18)20/h3-4,7-8,14-15,22H,5-6,9-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301990 (2-(4-(3-(5-Fluoro-1H-indol-3-yl)propyl)piperazin-1...) Show SMILES Cc1nc(sc1C#N)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C20H22FN5S/c1-14-19(12-22)27-20(24-14)26-9-7-25(8-10-26)6-2-3-15-13-23-18-5-4-16(21)11-17(15)18/h4-5,11,13,23H,2-3,6-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301986 (2-(4-(3-(5-Fluoro-1H-indol-3-yl)propyl)piperazin-1...) Show SMILES Cc1nc(sc1C(N)=O)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C20H24FN5OS/c1-13-18(19(22)27)28-20(24-13)26-9-7-25(8-10-26)6-2-3-14-12-23-17-5-4-15(21)11-16(14)17/h4-5,11-12,23H,2-3,6-10H2,1H3,(H2,22,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301952 (3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C21H27N5O2/c1-27-19-14-20(28-2)24-21(23-19)26-12-10-25(11-13-26)9-5-6-16-15-22-18-8-4-3-7-17(16)18/h3-4,7-8,14-15,22H,5-6,9-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301991 (2-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-y...) Show SMILES Cc1nc(sc1C#N)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H24N6S/c1-16-21(14-24)29-22(26-16)28-10-8-27(9-11-28)7-3-2-4-18-15-25-20-6-5-17(13-23)12-19(18)20/h5-6,12,15,25H,2-4,7-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301981 (Ethyl 2-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)pipera...) Show SMILES CCOC(=O)c1sc(nc1C)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C23H29FN4O2S/c1-3-30-22(29)21-16(2)26-23(31-21)28-12-10-27(11-13-28)9-5-4-6-17-15-25-20-8-7-18(24)14-19(17)20/h7-8,14-15,25H,3-6,9-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301970 (3-(4-(4-(4-Cyanopyrimidin-2-yl)piperazin-1-yl)buty...) Show SMILES N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3nccc(n3)C#N)c2c1 Show InChI InChI=1S/C22H23N7/c23-14-17-4-5-21-20(13-17)18(16-26-21)3-1-2-8-28-9-11-29(12-10-28)22-25-7-6-19(15-24)27-22/h4-7,13,16,26H,1-3,8-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301972 (3-(3-(4-(4-Cyanopyrimidin-2-yl)piperazin-1-yl)prop...) Show SMILES N#Cc1ccc2[nH]cc(CCCN3CCN(CC3)c3nccc(n3)C#N)c2c1 Show InChI InChI=1S/C21H21N7/c22-13-16-3-4-20-19(12-16)17(15-25-20)2-1-7-27-8-10-28(11-9-27)21-24-6-5-18(14-23)26-21/h3-6,12,15,25H,1-2,7-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301974 (2-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-y...) Show SMILES NC(=O)c1ccnc(n1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H25N7O/c23-14-16-4-5-19-18(13-16)17(15-26-19)3-1-2-8-28-9-11-29(12-10-28)22-25-7-6-20(27-22)21(24)30/h4-7,13,15,26H,1-3,8-12H2,(H2,24,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301975 (2-(4-(3-(5-Fluoro-1H-indol-3-yl)propyl)piperazin-1...) Show SMILES NC(=O)c1ccnc(n1)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C20H23FN6O/c21-15-3-4-17-16(12-15)14(13-24-17)2-1-7-26-8-10-27(11-9-26)20-23-6-5-18(25-20)19(22)28/h3-6,12-13,24H,1-2,7-11H2,(H2,22,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301987 (2-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-y...) Show SMILES Cc1nc(sc1C(N)=O)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H26N6OS/c1-15-20(21(24)29)30-22(26-15)28-10-8-27(9-11-28)7-3-2-4-17-14-25-19-6-5-16(13-23)12-18(17)19/h5-6,12,14,25H,2-4,7-11H2,1H3,(H2,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301989 (2-(4-(4-(5-Fluoro-1H-indol-3-yl)butyl)piperazin-1-...) Show SMILES Cc1nc(sc1C#N)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C21H24FN5S/c1-15-20(13-23)28-21(25-15)27-10-8-26(9-11-27)7-3-2-4-16-14-24-19-6-5-17(22)12-18(16)19/h5-6,12,14,24H,2-4,7-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301976 (2-(4-(3-(5-Cyano-1H-indol-3-yl)propyl)piperazin-1-...) Show SMILES NC(=O)c1ccnc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C21H23N7O/c22-13-15-3-4-18-17(12-15)16(14-25-18)2-1-7-27-8-10-28(11-9-27)21-24-6-5-19(26-21)20(23)29/h3-6,12,14,25H,1-2,7-11H2,(H2,23,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301969 (2-(4-(4-(5-Fluoro-1H-indol-3-yl)butyl)piperazin-1-...) Show SMILES Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3nccc(n3)C#N)c2c1 Show InChI InChI=1S/C21H23FN6/c22-17-4-5-20-19(13-17)16(15-25-20)3-1-2-8-27-9-11-28(12-10-27)21-24-7-6-18(14-23)26-21/h4-7,13,15,25H,1-3,8-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301985 (2-(4-(4-(5-Fluoro-1H-indol-3-yl)butyl)piperazin-1-...) Show SMILES Cc1nc(sc1C(N)=O)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C21H26FN5OS/c1-14-19(20(23)28)29-21(25-14)27-10-8-26(9-11-27)7-3-2-4-15-13-24-18-6-5-16(22)12-17(15)18/h5-6,12-13,24H,2-4,7-11H2,1H3,(H2,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301973 (2-(4-(4-(5-Fluoro-1H-indol-3-yl)butyl)piperazin-1-...) Show SMILES NC(=O)c1ccnc(n1)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C21H25FN6O/c22-16-4-5-18-17(13-16)15(14-25-18)3-1-2-8-27-9-11-28(12-10-27)21-24-7-6-19(26-21)20(23)29/h4-7,13-14,25H,1-3,8-12H2,(H2,23,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM301950 (3-(4-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C22H28FN5O2/c1-29-20-14-21(30-2)26-22(25-20)28-11-9-27(10-12-28)8-4-3-5-16-15-24-19-7-6-17(23)13-18(16)19/h6-7,13-15,24H,3-5,8-12H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Cell membrane homogenates (24 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]methyl-spiperone in the absence or presence of...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM301962 (3-(3-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C21H27N5/c1-16-14-17(2)24-21(23-16)26-12-10-25(11-13-26)9-5-6-18-15-22-20-8-4-3-7-19(18)20/h3-4,7-8,14-15,22H,5-6,9-13H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Cell membrane homogenates (24 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]methyl-spiperone in the absence or presence of...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM301991 (2-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-y...) Show SMILES Cc1nc(sc1C#N)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H24N6S/c1-16-21(14-24)29-22(26-16)28-10-8-27(9-11-28)7-3-2-4-18-15-25-20-6-5-17(13-23)12-19(18)20/h5-6,12,15,25H,2-4,7-11H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Cell membrane homogenates (24 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]methyl-spiperone in the absence or presence of...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM301981 (Ethyl 2-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)pipera...) Show SMILES CCOC(=O)c1sc(nc1C)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C23H29FN4O2S/c1-3-30-22(29)21-16(2)26-23(31-21)28-12-10-27(11-13-28)9-5-4-6-17-15-25-20-8-7-18(24)14-19(17)20/h7-8,14-15,25H,3-6,9-13H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Cell membrane homogenates (24 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]methyl-spiperone in the absence or presence of...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 63 total )  |  Next  |  Last  >>

Jump to: