Compile Data Set for Download or QSAR

Found 75 hits Enz. Inhib. hit(s) with Target = 'Protein c-Fos/Transcription factor Jun'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090430 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cccs1 |t:16| Show InChI InChI=1S/C16H14N4O4S/c1-3-24-16(23)10-8-17-14(11-5-4-6-25-11)18-13(10)19-20-12(21)7-9(2)15(20)22/h4-8H,3H2,1-2H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090407 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccsc1 |t:16| Show InChI InChI=1S/C16H14N4O4S/c1-3-24-16(23)11-7-17-13(10-4-5-25-8-10)18-14(11)19-20-12(21)6-9(2)15(20)22/h4-8H,3H2,1-2H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090444 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccccc1 |t:16| Show InChI InChI=1S/C18H16N4O4/c1-3-26-18(25)13-10-19-15(12-7-5-4-6-8-12)20-16(13)21-22-14(23)9-11(2)17(22)24/h4-10H,3H2,1-2H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090442 (3-Methyl-1-[5-(2-methyl-2H-tetrazol-5-yl)-2-thioph...) Show SMILES CC1=CC(=O)N(Nc2nc(ncc2-c2nnn(C)n2)-c2cccs2)C1=O |t:1| Show InChI InChI=1S/C15H12N8O2S/c1-8-6-11(24)23(15(8)25)20-12-9(13-18-21-22(2)19-13)7-16-14(17-12)10-4-3-5-26-10/h3-7H,1-2H3,(H,16,17,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090443 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(SC)nc1NN1C(=O)C=C(C)C1=O |t:18| Show InChI InChI=1S/C13H14N4O4S/c1-4-21-12(20)8-6-14-13(22-3)15-10(8)16-17-9(18)5-7(2)11(17)19/h5-6H,4H2,1-3H3,(H,14,15,16)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090420 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccc(C)s1 |t:16| Show InChI InChI=1S/C17H16N4O4S/c1-4-25-17(24)11-8-18-15(12-6-5-10(3)26-12)19-14(11)20-21-13(22)7-9(2)16(21)23/h5-8H,4H2,1-3H3,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090406 (1-(5-(4,5-dihydrooxazol-2-yl)-2-(thiophen-2-yl)pyr...) Show SMILES CC1=CC(=O)N(Nc2nc(ncc2C2=NCCO2)-c2cccs2)C1=O |t:1,14| Show InChI InChI=1S/C16H13N5O3S/c1-9-7-12(22)21(16(9)23)20-13-10(15-17-4-5-24-15)8-18-14(19-13)11-3-2-6-25-11/h2-3,6-8H,4-5H2,1H3,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090431 (3-Methyl-1-[5-(4-methyl-oxazol-2-yl)-2-thiophen-2-...) Show SMILES CC1=CC(=O)N(Nc2nc(ncc2-c2nc(C)co2)-c2cccs2)C1=O |t:1| Show InChI InChI=1S/C17H13N5O3S/c1-9-6-13(23)22(17(9)24)21-14-11(16-19-10(2)8-25-16)7-18-15(20-14)12-4-3-5-26-12/h3-8H,1-2H3,(H,18,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090435 (3-Methyl-1-[5-(3-methyl-isoxazol-5-yl)-2-thiophen-...) Show SMILES CC1=CC(=O)N(Nc2nc(ncc2-c2cc(C)no2)-c2cccs2)C1=O |t:1| Show InChI InChI=1S/C17H13N5O3S/c1-9-6-14(23)22(17(9)24)20-15-11(12-7-10(2)21-25-12)8-18-16(19-15)13-4-3-5-26-13/h3-8H,1-2H3,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090433 (2-(5-Chloro-thiophen-2-yl)-4-(3-methyl-2,5-dioxo-2...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccc(Cl)s1 |t:16| Show InChI InChI=1S/C16H13ClN4O4S/c1-3-25-16(24)9-7-18-14(10-4-5-11(17)26-10)19-13(9)20-21-12(22)6-8(2)15(21)23/h4-7H,3H2,1-2H3,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090450 (3-Methyl-1-[5-(5-methyl-[1,3,4]oxadiazol-2-yl)-2-t...) Show SMILES CC1=CC(=O)N(Nc2nc(ncc2-c2nnc(C)o2)-c2cccs2)C1=O |t:1| Show InChI InChI=1S/C16H12N6O3S/c1-8-6-12(23)22(16(8)24)21-13-10(15-20-19-9(2)25-15)7-17-14(18-13)11-4-3-5-26-11/h3-7H,1-2H3,(H,17,18,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090429 (2-(3,5-Dichloro-phenyl)-4-(3-methyl-2,5-dioxo-2,5-...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cc(Cl)cc(Cl)c1 |t:16| Show InChI InChI=1S/C18H14Cl2N4O4/c1-3-28-18(27)13-8-21-15(10-5-11(19)7-12(20)6-10)22-16(13)23-24-14(25)4-9(2)17(24)26/h4-8H,3H2,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090449 (2-(4-Chloro-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dihy...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccc(Cl)cc1 |t:16| Show InChI InChI=1S/C18H15ClN4O4/c1-3-27-18(26)13-9-20-15(11-4-6-12(19)7-5-11)21-16(13)22-23-14(24)8-10(2)17(23)25/h4-9H,3H2,1-2H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090440 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccc(cc1)C(F)(F)F |t:16| Show InChI InChI=1S/C19H15F3N4O4/c1-3-30-18(29)13-9-23-15(11-4-6-12(7-5-11)19(20,21)22)24-16(13)25-26-14(27)8-10(2)17(26)28/h4-9H,3H2,1-2H3,(H,23,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090421 (2-(Furan-2-carbonyl)-4-(3-methyl-2,5-dioxo-2,5-dih...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)C(=O)c1ccco1 |t:16| Show InChI InChI=1S/C17H14N4O6/c1-3-26-17(25)10-8-18-15(13(23)11-5-4-6-27-11)19-14(10)20-21-12(22)7-9(2)16(21)24/h4-8H,3H2,1-2H3,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090426 (2-(4-Fluoro-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dihy...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccc(F)cc1 |t:16| Show InChI InChI=1S/C18H15FN4O4/c1-3-27-18(26)13-9-20-15(11-4-6-12(19)7-5-11)21-16(13)22-23-14(24)8-10(2)17(23)25/h4-9H,3H2,1-2H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090441 (2-(3-Bromo-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dihyd...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cccc(Br)c1 |t:16| Show InChI InChI=1S/C18H15BrN4O4/c1-3-27-18(26)13-9-20-15(11-5-4-6-12(19)8-11)21-16(13)22-23-14(24)7-10(2)17(23)25/h4-9H,3H2,1-2H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090409 (2-(4-Methoxy-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dih...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccc(OC)cc1 |t:16| Show InChI InChI=1S/C19H18N4O5/c1-4-28-19(26)14-10-20-16(12-5-7-13(27-3)8-6-12)21-17(14)22-23-15(24)9-11(2)18(23)25/h5-10H,4H2,1-3H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090410 (4-[Methyl-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1...) Show SMILES CCOC(=O)c1cnc(nc1N(C)N1C(=O)C=C(C)C1=O)-c1cccs1 |t:17| Show InChI InChI=1S/C17H16N4O4S/c1-4-25-17(24)11-9-18-14(12-6-5-7-26-12)19-15(11)20(3)21-13(22)8-10(2)16(21)23/h5-9H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090447 (2-tert-Butyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyr...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)C(C)(C)C |t:16| Show InChI InChI=1S/C16H20N4O4/c1-6-24-14(23)10-8-17-15(16(3,4)5)18-12(10)19-20-11(21)7-9(2)13(20)22/h7-8H,6H2,1-5H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090408 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)C(F)(F)F |t:16| Show InChI InChI=1S/C13H11F3N4O4/c1-3-24-11(23)7-5-17-12(13(14,15)16)18-9(7)19-20-8(21)4-6(2)10(20)22/h4-5H,3H2,1-2H3,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090432 (2-Cyclopropyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-py...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)C1CC1 |t:16| Show InChI InChI=1S/C15H16N4O4/c1-3-23-15(22)10-7-16-12(9-4-5-9)17-13(10)18-19-11(20)6-8(2)14(19)21/h6-7,9H,3-5H2,1-2H3,(H,16,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090415 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(Sc2ccccc2)nc1NN1C(=O)C=C(C)C1=O |t:24| Show InChI InChI=1S/C18H16N4O4S/c1-3-26-17(25)13-10-19-18(27-12-7-5-4-6-8-12)20-15(13)21-22-14(23)9-11(2)16(22)24/h4-10H,3H2,1-2H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090437 (2-Cyclohex-1-enylmethyl-4-(3-methyl-2,5-dioxo-2,5-...) Show SMILES CCOC(=O)c1cnc(CC2=CCCCC2)nc1NN1C(=O)C=C(C)C1=O |t:10,24| Show InChI InChI=1S/C19H22N4O4/c1-3-27-19(26)14-11-20-15(10-13-7-5-4-6-8-13)21-17(14)22-23-16(24)9-12(2)18(23)25/h7,9,11H,3-6,8,10H2,1-2H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090436 (4-[Methyl-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1...) Show SMILES CCOC(=O)c1cnc(nc1N(C)N1C(=O)C=C(C)C1=O)-c1ccccc1 |t:17| Show InChI InChI=1S/C19H18N4O4/c1-4-27-19(26)14-11-20-16(13-8-6-5-7-9-13)21-17(14)22(3)23-15(24)10-12(2)18(23)25/h5-11H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090411 (2-(2,6-Dichloro-pyridin-4-yl)-4-(3-methyl-2,5-diox...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cc(Cl)nc(Cl)c1 |t:16| Show InChI InChI=1S/C17H13Cl2N5O4/c1-3-28-17(27)10-7-20-14(9-5-11(18)21-12(19)6-9)22-15(10)23-24-13(25)4-8(2)16(24)26/h4-7H,3H2,1-2H3,(H,20,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090445 (2-(4-Fluoro-phenyl)-4-[methyl-(3-methyl-2,5-dioxo-...) Show SMILES CCOC(=O)c1cnc(nc1N(C)N1C(=O)C=C(C)C1=O)-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C19H17FN4O4/c1-4-28-19(27)14-10-21-16(12-5-7-13(20)8-6-12)22-17(14)23(3)24-15(25)9-11(2)18(24)26/h5-10H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090425 (4-[Acetyl-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1...) Show SMILES CCOC(=O)c1cnc(nc1N(N1C(=O)C=C(C)C1=O)C(C)=O)-c1ccccc1 |t:16| Show InChI InChI=1S/C20H18N4O5/c1-4-29-20(28)15-11-21-17(14-8-6-5-7-9-14)22-18(15)23(13(3)25)24-16(26)10-12(2)19(24)27/h5-11H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090439 (2-Benzo[b]thiophen-2-yl-4-(3-methyl-2,5-dioxo-2,5-...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cc2ccccc2s1 |t:16| Show InChI InChI=1S/C20H16N4O4S/c1-3-28-20(27)13-10-21-18(15-9-12-6-4-5-7-14(12)29-15)22-17(13)23-24-16(25)8-11(2)19(24)26/h4-10H,3H2,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090428 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CC1=CC(=O)N(Nc2nc(ncc2C#N)-c2cccs2)C1=O |t:1| Show InChI InChI=1S/C14H9N5O2S/c1-8-5-11(20)19(14(8)21)18-12-9(6-15)7-16-13(17-12)10-3-2-4-22-10/h2-5,7H,1H3,(H,16,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50180049 (3-[2-isobutoxy-5-(4-isobutoxybenzoyl)phenyl]propio...) Show SMILES CC(C)COc1ccc(cc1)C(=O)c1ccc(OCC(C)C)c(CCC(O)=O)c1 Show InChI InChI=1S/C24H30O5/c1-16(2)14-28-21-9-5-18(6-10-21)24(27)20-7-11-22(29-15-17(3)4)19(13-20)8-12-23(25)26/h5-7,9-11,13,16-17H,8,12,14-15H2,1-4H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Chemical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of the expression of AP1-luciferase by TPA-stimulated NIH3T3 cells				J Med Chem 49: 80-91 (2006) Article DOI: 10.1021/jm050550d BindingDB Entry DOI: 10.7270/Q2VX0G2C
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090427 (2-(3-Methoxy-phenyl)-4-(3-methyl-2,5-dioxo-2,5-dih...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cccc(OC)c1 |t:16| Show InChI InChI=1S/C19H18N4O5/c1-4-28-19(26)14-10-20-16(12-6-5-7-13(9-12)27-3)21-17(14)22-23-15(24)8-11(2)18(23)25/h5-10H,4H2,1-3H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50180047 (3-[2-isobutoxy-5-(3-isobutoxybenzoyl)phenyl]propio...) Show SMILES CC(C)COc1cccc(c1)C(=O)c1ccc(OCC(C)C)c(CCC(O)=O)c1 Show InChI InChI=1S/C24H30O5/c1-16(2)14-28-21-7-5-6-19(13-21)24(27)20-8-10-22(29-15-17(3)4)18(12-20)9-11-23(25)26/h5-8,10,12-13,16-17H,9,11,14-15H2,1-4H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Chemical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of the expression of AP1-luciferase by TPA-stimulated NIH3T3 cells				J Med Chem 49: 80-91 (2006) Article DOI: 10.1021/jm050550d BindingDB Entry DOI: 10.7270/Q2VX0G2C
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090446 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1ccncc1 |t:16| Show InChI InChI=1S/C17H15N5O4/c1-3-26-17(25)12-9-19-14(11-4-6-18-7-5-11)20-15(12)21-22-13(23)8-10(2)16(22)24/h4-9H,3H2,1-2H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090423 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cnc2ccccc2c1 |t:16| Show InChI InChI=1S/C21H17N5O4/c1-3-30-21(29)15-11-23-18(14-9-13-6-4-5-7-16(13)22-10-14)24-19(15)25-26-17(27)8-12(2)20(26)28/h4-11H,3H2,1-2H3,(H,23,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090422 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cccc(c1)[N+]([O-])=O |t:16| Show InChI InChI=1S/C18H15N5O6/c1-3-29-18(26)13-9-19-15(11-5-4-6-12(8-11)23(27)28)20-16(13)21-22-14(24)7-10(2)17(22)25/h4-9H,3H2,1-2H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090414 (2-Benzyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-...) Show SMILES CCOC(=O)c1cnc(Cc2ccccc2)nc1NN1C(=O)C=C(C)C1=O |t:24| Show InChI InChI=1S/C19H18N4O4/c1-3-27-19(26)14-11-20-15(10-13-7-5-4-6-8-13)21-17(14)22-23-16(24)9-12(2)18(23)25/h4-9,11H,3,10H2,1-2H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090417 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1csc(C)n1 |t:16| Show InChI InChI=1S/C16H15N5O4S/c1-4-25-16(24)10-6-17-14(11-7-26-9(3)18-11)19-13(10)20-21-12(22)5-8(2)15(21)23/h5-7H,4H2,1-3H3,(H,17,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50151079 ((S)-3-{(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-(2-Amino-...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)CN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(O)=O Show InChI InChI=1S/C32H53N9O14/c1-14(2)8-18(30(53)36-16(5)27(50)38-20(10-24(44)45)28(51)35-13-26(48)49)40-32(55)21(11-25(46)47)41-31(54)19(9-15(3)4)39-29(52)17(6-7-22(34)42)37-23(43)12-33/h14-21H,6-13,33H2,1-5H3,(H2,34,42)(H,35,51)(H,36,53)(H,37,43)(H,38,50)(H,39,52)(H,40,55)(H,41,54)(H,44,45)(H,46,47)(H,48,49)/t16-,17-,18-,19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Chemical Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against transcription activator protein-1 (AP-1)				J Med Chem 47: 4239-46 (2004) Article DOI: 10.1021/jm049890+ BindingDB Entry DOI: 10.7270/Q2RX9BJG
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090419 (4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-ylamino)-2-trifl...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=CC1=O)C(F)(F)F |c:16| Show InChI InChI=1S/C12H9F3N4O4/c1-2-23-10(22)6-5-16-11(12(13,14)15)17-9(6)18-19-7(20)3-4-8(19)21/h3-5H,2H2,1H3,(H,16,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090424 (2-Benzenesulfonyl-4-(3-methyl-2,5-dioxo-2,5-dihydr...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)S(=O)(=O)c1ccccc1 |t:16| Show InChI InChI=1S/C18H16N4O6S/c1-3-28-17(25)13-10-19-18(29(26,27)12-7-5-4-6-8-12)20-15(13)21-22-14(23)9-11(2)16(22)24/h4-10H,3H2,1-2H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090438 (2-(3,5-Dimethyl-pyrazol-1-yl)-4-(3-methyl-2,5-diox...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-n1nc(C)cc1C |t:16| Show InChI InChI=1S/C17H18N6O4/c1-5-27-16(26)12-8-18-17(22-11(4)7-10(3)20-22)19-14(12)21-23-13(24)6-9(2)15(23)25/h6-8H,5H2,1-4H3,(H,18,19,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090434 (4-(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-pyrrol-1-yla...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C(C)=C(C)C1=O)C(F)(F)F |t:17| Show InChI InChI=1S/C14H13F3N4O4/c1-4-25-12(24)8-5-18-13(14(15,16)17)19-9(8)20-21-10(22)6(2)7(3)11(21)23/h5H,4H2,1-3H3,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090416 (2-Ethyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1...) Show SMILES CCOC(=O)c1cnc(CC)nc1NN1C(=O)C=C(C)C1=O |t:18| Show InChI InChI=1S/C14H16N4O4/c1-4-10-15-7-9(14(21)22-5-2)12(16-10)17-18-11(19)6-8(3)13(18)20/h6-7H,4-5H2,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090413 (2-Ethyl-4-[methyl-(3-methyl-2,5-dioxo-2,5-dihydro-...) Show SMILES CCOC(=O)c1cnc(CC)nc1N(C)N1C(=O)C=C(C)C1=O |t:19| Show InChI InChI=1S/C15H18N4O4/c1-5-11-16-8-10(15(22)23-6-2)13(17-11)18(4)19-12(20)7-9(3)14(19)21/h7-8H,5-6H2,1-4H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50180051 ((R)-4-(4-methylpentanoyl)-8-(4-methylpentylidene)-...) Show SMILES CC(C)CCC=C1CCC2(CC1)SC[C@H](N2C(=O)CCC(C)C)C(O)=O |wU:14.24,(-7.53,4.55,;-6,4.62,;-5.29,5.99,;-5.17,3.32,;-3.63,3.39,;-2.8,2.1,;-1.26,2.17,;-.42,.88,;1.12,.95,;1.82,2.31,;1,3.6,;-.54,3.53,;2.67,3.6,;4.15,3.19,;4.22,1.65,;2.78,1.11,;2.37,-.38,;.88,-.77,;3.45,-1.47,;3.05,-2.96,;4.13,-4.05,;3.72,-5.54,;5.62,-3.66,;5.51,.8,;6.88,1.49,;5.42,-.73,)| Show InChI InChI=1S/C21H35NO3S/c1-15(2)6-5-7-17-10-12-21(13-11-17)22(18(14-26-21)20(24)25)19(23)9-8-16(3)4/h7,15-16,18H,5-6,8-14H2,1-4H3,(H,24,25)/b17-7-/t18-,21?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Chemical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of the expression of AP1-luciferase by TPA-stimulated NIH3T3 cells				J Med Chem 49: 80-91 (2006) Article DOI: 10.1021/jm050550d BindingDB Entry DOI: 10.7270/Q2VX0G2C
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50180048 ((R)-8-(3-methylbutylidene)-4-(5-methylhexanoyl)-1-...) Show SMILES CC(C)CCCC(=O)N1[C@@H](CSC11CCC(CC1)=CCC(C)C)C(O)=O |wU:9.24,(8.93,-9.16,;7.84,-8.07,;8.25,-6.58,;6.35,-8.46,;5.27,-7.36,;5.68,-5.88,;4.6,-4.78,;3.11,-5.17,;5,-3.29,;6.45,-2.75,;6.37,-1.21,;4.89,-.81,;4.04,-2.09,;3.34,-3.46,;1.8,-3.53,;.97,-2.23,;1.68,-.87,;3.22,-.8,;-.57,-2.31,;-1.4,-1.01,;-2.94,-1.08,;-3.77,.22,;-3.65,-2.45,;7.73,-3.6,;9.11,-2.91,;7.64,-5.14,)| Show InChI InChI=1S/C21H35NO3S/c1-15(2)6-5-7-19(23)22-18(20(24)25)14-26-21(22)12-10-17(11-13-21)9-8-16(3)4/h9,15-16,18H,5-8,10-14H2,1-4H3,(H,24,25)/b17-9-/t18-,21?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Chemical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of the expression of AP1-luciferase by TPA-stimulated NIH3T3 cells				J Med Chem 49: 80-91 (2006) Article DOI: 10.1021/jm050550d BindingDB Entry DOI: 10.7270/Q2VX0G2C
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090418 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(Oc2ccccc2)nc1NN1C(=O)C=C(C)C1=O |t:24| Show InChI InChI=1S/C18H16N4O5/c1-3-26-17(25)13-10-19-18(27-12-7-5-4-6-8-12)20-15(13)21-22-14(23)9-11(2)16(22)24/h4-10H,3H2,1-2H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090448 (2-Methyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-...) Show SMILES CCOC(=O)c1cnc(C)nc1NN1C(=O)C=C(C)C1=O |t:17| Show InChI InChI=1S/C13H14N4O4/c1-4-21-13(20)9-6-14-8(3)15-11(9)16-17-10(18)5-7(2)12(17)19/h5-6H,4H2,1-3H3,(H,14,15,16)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair
Protein c-Fos/Transcription factor Jun (Homo sapiens (Human))	BDBM50090412 (4-(2,5-Dioxo-3-phenyl-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C1=O)c1ccccc1)C(F)(F)F |c:16| Show InChI InChI=1S/C18H13F3N4O4/c1-2-29-16(28)12-9-22-17(18(19,20)21)23-14(12)24-25-13(26)8-11(15(25)27)10-6-4-3-5-7-10/h3-9H,2H2,1H3,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair

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