Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245828 (2-Tosylnaphthalene-1,4-diol | CHEMBL509952) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245923 (2-(naphthalen-2-ylsulfonyl)naphthalene-1,4-diol | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.49 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245928 (2-tosylnaphthalene-1,4-dione | CHEMBL454282) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.99 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245877 (2-(phenylsulfonyl)naphthalene-1,4-diol | CHEMBL462...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.84 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245880 (2-(4-propylphenylsulfonyl)naphthalene-1,4-diol | C...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.09 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245830 (3-(1,4-dihydroxynaphthalen-2-ylsulfonyl)propanoic ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.53 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245829 (2-(methylsulfonyl)naphthalene-1,4-diol | CHEMBL491...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.53 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245879 (2-(4-chlorophenylsulfonyl)naphthalene-1,4-diol | C...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.61 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245878 (CHEMBL512926 | N-(4-(1,4-dihydroxynaphthalen-2-yls...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.76 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245924 (2-tosylanthracene-1,4-diol | CHEMBL451059) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.47 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245926 (CHEMBL462376 | N-(4-(2,5-dihydroxyphenylsulfonyl)p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245925 (2-tosylbenzene-1,4-diol | CHEMBL462375) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 34.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245831 (2-(p-tolylthio)naphthalene-1,4-dione | CHEMBL50155...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50245927 (2-tosylnaphthalene | CHEMBL462553) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Portland State University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 18: 6402-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.097 BindingDB Entry DOI: 10.7270/Q2542PGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233092 (mtFabH inhibitor, 39) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50220630 (5-(4-methoxycarbonyl-biphenyl-4-ylmethyl)-4-hydrox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Birmingham Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 17: 5643-6 (2007) Article DOI: 10.1016/j.bmcl.2007.07.082 BindingDB Entry DOI: 10.7270/Q2QF8TPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50241313 ((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibitory activity against KasA from Mycobacterium tuberculosis H37Rv | J Med Chem 49: 159-71 (2006) Article DOI: 10.1021/jm050825p BindingDB Entry DOI: 10.7270/Q2NG4RDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233091 (mtFabH inhibitor, 38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233056 (mtFabH inhibitor, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50220624 (4'-(3-hydroxy-2,4-dimethyl-5-oxo-2,5-dihydro-thiop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Birmingham Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 17: 5643-6 (2007) Article DOI: 10.1016/j.bmcl.2007.07.082 BindingDB Entry DOI: 10.7270/Q2QF8TPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233090 (mtFabH inhibitor, 37) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233076 (mtFabH inhibitor, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233057 (mtFabH inhibitor, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50220629 (4'-(3-hydroxy-2,4-dimethyl-5-oxo-2,5-dihydro-thiop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Birmingham Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 17: 5643-6 (2007) Article DOI: 10.1016/j.bmcl.2007.07.082 BindingDB Entry DOI: 10.7270/Q2QF8TPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50220625 (4-hydroxy-3,5-dimethyl-5-(4-phenoxy-benzyl)-5H-thi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Birmingham Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 17: 5643-6 (2007) Article DOI: 10.1016/j.bmcl.2007.07.082 BindingDB Entry DOI: 10.7270/Q2QF8TPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233070 (mtFabH inhibitor, 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50134362 (5-(4'-Benzyloxymethyl-biphenyl-4-ylmethyl)-4-hydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme. | Bioorg Med Chem Lett 13: 3685-8 (2003) BindingDB Entry DOI: 10.7270/Q20864R5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50134348 (4-Hydroxy-5-(4'-hydroxymethyl-biphenyl-4-ylmethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme. | Bioorg Med Chem Lett 13: 3685-8 (2003) BindingDB Entry DOI: 10.7270/Q20864R5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233069 (mtFabH inhibitor, 23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233067 (mtFabH inhibitor, 21) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50134356 (5-(4'-tert-Butyl-biphenyl-4-ylmethyl)-4-hydroxy-3,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme. | Bioorg Med Chem Lett 13: 3685-8 (2003) BindingDB Entry DOI: 10.7270/Q20864R5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50180128 (5-((E)-buta-1,3-dienyl)-3,5-dimethyl-4-hydroxy-5H-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibitory activity against KasA from Mycobacterium tuberculosis H37Rv | J Med Chem 49: 159-71 (2006) Article DOI: 10.1021/jm050825p BindingDB Entry DOI: 10.7270/Q2NG4RDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233068 (mtFabH inhibitor, 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50134352 (4'-(3-Hydroxy-2,4-dimethyl-5-oxo-2,5-dihydro-thiop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme. | Bioorg Med Chem Lett 13: 3685-8 (2003) BindingDB Entry DOI: 10.7270/Q20864R5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233075 (mtFabH inhibitor, 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50134355 (5-(4-tert-Butyl-benzyl)-4-hydroxy-3,5-dimethyl-5H-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme. | Bioorg Med Chem Lett 13: 3685-8 (2003) BindingDB Entry DOI: 10.7270/Q20864R5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233060 (mtFabH inhibitor, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233058 (mtFabH inhibitor, 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50180135 ((R)-3,5-dimethyl-4-hydroxy-5-((1E,3E)-2-methylpent...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibitory activity against KasA from Mycobacterium tuberculosis H37Rv | J Med Chem 49: 159-71 (2006) Article DOI: 10.1021/jm050825p BindingDB Entry DOI: 10.7270/Q2NG4RDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50180141 (3,5-dimethyl-5-dodecyl-4-hydroxy-5H-thiophen-2-one...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibitory activity against FabH from Mycobacterium tuberculosis H37Rv | J Med Chem 49: 159-71 (2006) Article DOI: 10.1021/jm050825p BindingDB Entry DOI: 10.7270/Q2NG4RDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233064 (mtFabH inhibitor, 17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50134361 (5-Biphenyl-4-ylmethyl-4-hydroxy-3,5-dimethyl-5H-th...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme. | Bioorg Med Chem Lett 13: 3685-8 (2003) BindingDB Entry DOI: 10.7270/Q20864R5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50134360 (4-Hydroxy-3,5-dimethyl-5-(4'-methyl-biphenyl-4-ylm...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme. | Bioorg Med Chem Lett 13: 3685-8 (2003) BindingDB Entry DOI: 10.7270/Q20864R5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233079 (mtFabH inhibitor, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50134351 (4-Hydroxy-3,5-dimethyl-5-(3-phenoxy-benzyl)-5H-thi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme. | Bioorg Med Chem Lett 13: 3685-8 (2003) BindingDB Entry DOI: 10.7270/Q20864R5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233066 (mtFabH inhibitor, 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50220627 (5-(4'-acetyl-biphenyl-4-ylmethyl)-4-hydroxy-3,5-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Birmingham Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 17: 5643-6 (2007) Article DOI: 10.1016/j.bmcl.2007.07.082 BindingDB Entry DOI: 10.7270/Q2QF8TPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50180122 (3,5-dimethyl-4-hydroxy-5-(1-methylundecyl)-5H-thio...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Allergy and Infectious Diseases Curated by ChEMBL | Assay Description Inhibitory activity against FabH from Mycobacterium tuberculosis H37Rv | J Med Chem 49: 159-71 (2006) Article DOI: 10.1021/jm050825p BindingDB Entry DOI: 10.7270/Q2NG4RDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM50220634 (4-hydroxy-3,5-dimethyl-5-[1,1';4',1'']terphenyl-4-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Birmingham Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FabH | Bioorg Med Chem Lett 17: 5643-6 (2007) Article DOI: 10.1016/j.bmcl.2007.07.082 BindingDB Entry DOI: 10.7270/Q2QF8TPJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Mycobacterium tuberculosis) | BDBM233087 (mtFabH inhibitor, 34) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair |
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