Compile Data Set for Download or QSAR

Found 79 hits with Last Name = 'mazzulla' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371914 (CHEMBL403661) Show SMILES CCc1ccc(cc1)-c1c(-c2c[nH]c(C)n2)c(=O)[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C21H18ClN3O/c1-3-13-4-6-14(7-5-13)19-16-10-15(22)8-9-17(16)25-21(26)20(19)18-11-23-12(2)24-18/h4-11H,3H2,1-2H3,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371915 (CHEMBL273198) Show SMILES CCc1ccc(cc1)-c1c(-c2c[nH]c(C)n2)c(=O)[nH]c2ccc(cc12)C#N Show InChI InChI=1S/C22H18N4O/c1-3-14-4-7-16(8-5-14)20-17-10-15(11-23)6-9-18(17)26-22(27)21(20)19-12-24-13(2)25-19/h4-10,12H,3H2,1-2H3,(H,24,25)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236304 (1-(2-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)eth...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(Br)cc2c1CCNC(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H19BrFN3O3S/c24-16-8-11-21-20(14-16)19(22(27-21)15-6-9-17(25)10-7-15)12-13-26-23(29)28-32(30,31)18-4-2-1-3-5-18/h1-11,14,27H,12-13H2,(H2,26,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236292 (4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-(di...) Show SMILES CN(C)S(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN4O3S/c1-26(2)30(28,29)25-20(27)5-3-4-17-18-12-14(13-23)6-11-19(18)24-21(17)15-7-9-16(22)10-8-15/h6-12,24H,3-5H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236295 (4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(m...) Show SMILES CNS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C20H19FN4O3S/c1-23-29(27,28)25-19(26)4-2-3-16-17-11-13(12-22)5-10-18(17)24-20(16)14-6-8-15(21)9-7-14/h5-11,23-24H,2-4H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236312 (4-(5-cyano-2-(4-fluorophenyl)-6-methyl-1H-indol-3-...) Show SMILES Cc1cc2[nH]c(c(CCCC(=O)NS(C)(=O)=O)c2cc1C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H20FN3O3S/c1-13-10-19-18(11-15(13)12-23)17(4-3-5-20(26)25-29(2,27)28)21(24-19)14-6-8-16(22)9-7-14/h6-11,24H,3-5H2,1-2H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236318 (4-[5-cyano-2-(4-fluorophenyl)-6-methyl-1H-indol-3-...) Show SMILES CN(C)S(=O)(=O)NC(=O)CCCc1c([nH]c2cc(C)c(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN4O3S/c1-14-11-20-19(12-16(14)13-24)18(22(25-20)15-7-9-17(23)10-8-15)5-4-6-21(28)26-31(29,30)27(2)3/h7-12,25H,4-6H2,1-3H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236305 (4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(me...) Show SMILES CS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C20H18FN3O3S/c1-28(26,27)24-19(25)4-2-3-16-17-11-13(12-22)5-10-18(17)23-20(16)14-6-8-15(21)9-7-14/h5-11,23H,2-4H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50371914 (CHEMBL403661) Show SMILES CCc1ccc(cc1)-c1c(-c2c[nH]c(C)n2)c(=O)[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C21H18ClN3O/c1-3-13-4-6-14(7-5-13)19-16-10-15(22)8-9-17(16)25-21(26)20(19)18-11-23-12(2)24-18/h4-11H,3H2,1-2H3,(H,23,24)(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50371915 (CHEMBL273198) Show SMILES CCc1ccc(cc1)-c1c(-c2c[nH]c(C)n2)c(=O)[nH]c2ccc(cc12)C#N Show InChI InChI=1S/C22H18N4O/c1-3-14-4-7-16(8-5-14)20-17-10-15(11-23)6-9-18(17)26-22(27)21(20)19-12-24-13(2)25-19/h4-10,12H,3H2,1-2H3,(H,24,25)(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236292 (4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-(di...) Show SMILES CN(C)S(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN4O3S/c1-26(2)30(28,29)25-20(27)5-3-4-17-18-12-14(13-23)6-11-19(18)24-21(17)15-7-9-16(22)10-8-15/h6-12,24H,3-5H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236317 (4-[5-cyano-2-(4-fluorophenyl)-6-methoxy-1H-indol-3...) Show SMILES COc1cc2[nH]c(c(CCCC(=O)NS(=O)(=O)N(C)C)c2cc1C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN4O4S/c1-27(2)32(29,30)26-21(28)6-4-5-17-18-11-15(13-24)20(31-3)12-19(18)25-22(17)14-7-9-16(23)10-8-14/h7-12,25H,4-6H2,1-3H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236309 (4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(et...) Show SMILES CCS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H20FN3O3S/c1-2-29(27,28)25-20(26)5-3-4-17-18-12-14(13-23)6-11-19(18)24-21(17)15-7-9-16(22)10-8-15/h6-12,24H,2-5H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236307 (CHEMBL257830 | N-(aminosulfonyl)-4-[5-cyano-2-(4-f...) Show SMILES NS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C19H17FN4O3S/c20-14-7-5-13(6-8-14)19-15(2-1-3-18(25)24-28(22,26)27)16-10-12(11-21)4-9-17(16)23-19/h4-10,23H,1-3H2,(H,24,25)(H2,22,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50371914 (CHEMBL403661) Show SMILES CCc1ccc(cc1)-c1c(-c2c[nH]c(C)n2)c(=O)[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C21H18ClN3O/c1-3-13-4-6-14(7-5-13)19-16-10-15(22)8-9-17(16)25-21(26)20(19)18-11-23-12(2)24-18/h4-11H,3H2,1-2H3,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of KIT				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236303 (4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(tr...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCCC(=O)NS(=O)(=O)C(F)(F)F)C#N Show InChI InChI=1S/C20H15F4N3O3S/c21-14-7-5-13(6-8-14)19-15(16-10-12(11-25)4-9-17(16)26-19)2-1-3-18(28)27-31(29,30)20(22,23)24/h4-10,26H,1-3H2,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236305 (4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(me...) Show SMILES CS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C20H18FN3O3S/c1-28(26,27)24-19(25)4-2-3-16-17-11-13(12-22)5-10-18(17)23-20(16)14-6-8-15(21)9-7-14/h5-11,23H,2-4H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236303 (4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(tr...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCCC(=O)NS(=O)(=O)C(F)(F)F)C#N Show InChI InChI=1S/C20H15F4N3O3S/c21-14-7-5-13(6-8-14)19-15(16-10-12(11-25)4-9-17(16)26-19)2-1-3-18(28)27-31(29,30)20(22,23)24/h4-10,26H,1-3H2,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236296 (1-(2-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)eth...) Show SMILES CS(=O)(=O)NC(=O)NCCc1c([nH]c2ccc(Br)cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C18H17BrFN3O3S/c1-27(25,26)23-18(24)21-9-8-14-15-10-12(19)4-7-16(15)22-17(14)11-2-5-13(20)6-3-11/h2-7,10,22H,8-9H2,1H3,(H2,21,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371919 (CHEMBL436651) Show SMILES Cc1cc(on1)-c1c(C2=CCCCCC2)c2cc(Cl)ccc2[nH]c1=O |t:9| Show InChI InChI=1S/C20H19ClN2O2/c1-12-10-17(25-23-12)19-18(13-6-4-2-3-5-7-13)15-11-14(21)8-9-16(15)22-20(19)24/h6,8-11H,2-5,7H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371934 (CHEMBL272119) Show SMILES Cc1cc(on1)-c1c(-c2ccccc2)c2cc(ccc2[nH]c1=O)C#N Show InChI InChI=1S/C20H13N3O2/c1-12-9-17(25-23-12)19-18(14-5-3-2-4-6-14)15-10-13(11-21)7-8-16(15)22-20(19)24/h2-10H,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371923 (CHEMBL255213) Show SMILES CCc1ccc(cc1)-c1c(-c2cc(C)no2)c(=O)[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C21H17ClN2O2/c1-3-13-4-6-14(7-5-13)19-16-11-15(22)8-9-17(16)23-21(25)20(19)18-10-12(2)24-26-18/h4-11H,3H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371937 (CHEMBL255215) Show SMILES Cc1cc(on1)-c1c(-c2ccc(C)cc2)c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C20H15ClN2O2/c1-11-3-5-13(6-4-11)18-15-10-14(21)7-8-16(15)22-20(24)19(18)17-9-12(2)23-25-17/h3-10H,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236295 (4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(m...) Show SMILES CNS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C20H19FN4O3S/c1-23-29(27,28)25-19(26)4-2-3-16-17-11-13(12-22)5-10-18(17)24-20(16)14-6-8-15(21)9-7-14/h5-11,23-24H,2-4H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236304 (1-(2-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)eth...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(Br)cc2c1CCNC(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H19BrFN3O3S/c24-16-8-11-21-20(14-16)19(22(27-21)15-6-9-17(25)10-7-15)12-13-26-23(29)28-32(30,31)18-4-2-1-3-5-18/h1-11,14,27H,12-13H2,(H2,26,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371936 (CHEMBL270464) Show SMILES COc1ccc(cc1)-c1c(-c2cc(C)no2)c(=O)[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C20H15ClN2O3/c1-11-9-17(26-23-11)19-18(12-3-6-14(25-2)7-4-12)15-10-13(21)5-8-16(15)22-20(19)24/h3-10H,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM17751 (6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-4-phenyl-1,2...) Show SMILES Cc1cc(on1)-c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C19H13ClN2O2/c1-11-9-16(24-22-11)18-17(12-5-3-2-4-6-12)14-10-13(20)7-8-15(14)21-19(18)23/h2-10H,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236310 (1-(2-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)eth...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCNC(=O)NS(=O)(=O)c1ccccc1)C#N Show InChI InChI=1S/C24H19FN4O3S/c25-18-9-7-17(8-10-18)23-20(21-14-16(15-26)6-11-22(21)28-23)12-13-27-24(30)29-33(31,32)19-4-2-1-3-5-19/h1-11,14,28H,12-13H2,(H2,27,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236308 (4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(mo...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCCC(=O)NS(=O)(=O)N1CCOCC1)C#N Show InChI InChI=1S/C23H23FN4O4S/c24-18-7-5-17(6-8-18)23-19(20-14-16(15-25)4-9-21(20)26-23)2-1-3-22(29)27-33(30,31)28-10-12-32-13-11-28/h4-9,14,26H,1-3,10-13H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236316 (4-(5-cyano-2-(4-fluorophenyl)-6-methoxy-1H-indol-3...) Show SMILES COc1cc2[nH]c(c(CCCC(=O)NS(C)(=O)=O)c2cc1C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H20FN3O4S/c1-29-19-11-18-17(10-14(19)12-23)16(4-3-5-20(26)25-30(2,27)28)21(24-18)13-6-8-15(22)9-7-13/h6-11,24H,3-5H2,1-2H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236311 (4-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(me...) Show SMILES CS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(Br)cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C19H18BrFN2O3S/c1-27(25,26)23-18(24)4-2-3-15-16-11-13(20)7-10-17(16)22-19(15)12-5-8-14(21)9-6-12/h5-11,22H,2-4H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371921 (CHEMBL255634) Show SMILES Cc1cc(on1)-c1c(-c2ccc(O)cc2)c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C19H13ClN2O3/c1-10-8-16(25-22-10)18-17(11-2-5-13(23)6-3-11)14-9-12(20)4-7-15(14)21-19(18)24/h2-9,23H,1H3,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50371915 (CHEMBL273198) Show SMILES CCc1ccc(cc1)-c1c(-c2c[nH]c(C)n2)c(=O)[nH]c2ccc(cc12)C#N Show InChI InChI=1S/C22H18N4O/c1-3-14-4-7-16(8-5-14)20-17-10-15(11-23)6-9-18(17)26-22(27)21(20)19-12-24-13(2)25-19/h4-10,12H,3H2,1-2H3,(H,24,25)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of KIT				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371928 (CHEMBL258088) Show SMILES Clc1ccc2[nH]c(=O)c(-c3c[nH]cn3)c(-c3ccccc3)c2c1 Show InChI InChI=1S/C18H12ClN3O/c19-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)17(18(23)22-14)15-9-20-10-21-15/h1-10H,(H,20,21)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371922 (CHEMBL402429) Show SMILES CC(C)c1ccc(cc1)-c1c(-c2cc(C)no2)c(=O)[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C22H19ClN2O2/c1-12(2)14-4-6-15(7-5-14)20-17-11-16(23)8-9-18(17)24-22(26)21(20)19-10-13(3)25-27-19/h4-12H,1-3H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371920 (CHEMBL270463) Show SMILES Cc1cc(on1)-c1c(C2=CCCCC2)c2cc(Cl)ccc2[nH]c1=O |t:9| Show InChI InChI=1S/C19H17ClN2O2/c1-11-9-16(24-22-11)18-17(12-5-3-2-4-6-12)14-10-13(20)7-8-15(14)21-19(18)23/h5,7-10H,2-4,6H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236314 (4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(is...) Show SMILES CC(C)S(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C22H22FN3O3S/c1-14(2)30(28,29)26-21(27)5-3-4-18-19-12-15(13-24)6-11-20(19)25-22(18)16-7-9-17(23)10-8-16/h6-12,14,25H,3-5H2,1-2H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371917 (CHEMBL403621) Show SMILES Cc1cc(on1)-c1c(-c2cccc(C)c2)c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C20H15ClN2O2/c1-11-4-3-5-13(8-11)18-15-10-14(21)6-7-16(15)22-20(24)19(18)17-9-12(2)23-25-17/h3-10H,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236296 (1-(2-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)eth...) Show SMILES CS(=O)(=O)NC(=O)NCCc1c([nH]c2ccc(Br)cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C18H17BrFN3O3S/c1-27(25,26)23-18(24)21-9-8-14-15-10-12(19)4-7-16(15)22-17(14)11-2-5-13(20)6-3-11/h2-7,10,22H,8-9H2,1H3,(H2,21,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371941 (CHEMBL401691) Show SMILES Cc1cc(on1)-c1c(-c2ccccc2)c2cc(F)ccc2[nH]c1=O Show InChI InChI=1S/C19H13FN2O2/c1-11-9-16(24-22-11)18-17(12-5-3-2-4-6-12)14-10-13(20)7-8-15(14)21-19(18)23/h2-10H,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236300 (4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(ph...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCCC(=O)NS(=O)(=O)c1ccccc1)C#N Show InChI InChI=1S/C25H20FN3O3S/c26-19-12-10-18(11-13-19)25-21(22-15-17(16-27)9-14-23(22)28-25)7-4-8-24(30)29-33(31,32)20-5-2-1-3-6-20/h1-3,5-6,9-15,28H,4,7-8H2,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236302 (4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(2...) Show SMILES COCCNS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN4O4S/c1-31-12-11-25-32(29,30)27-21(28)4-2-3-18-19-13-15(14-24)5-10-20(19)26-22(18)16-6-8-17(23)9-7-16/h5-10,13,25-26H,2-4,11-12H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371927 (CHEMBL401736) Show SMILES O=c1[nH]c2ccc(cc2c(-c2ccccc2)c1-c1c[nH]cn1)C#N Show InChI InChI=1S/C19H12N4O/c20-9-12-6-7-15-14(8-12)17(13-4-2-1-3-5-13)18(19(24)23-15)16-10-21-11-22-16/h1-8,10-11H,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371931 (CHEMBL271479) Show SMILES CC(C)c1cc(on1)-c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C21H17ClN2O2/c1-12(2)17-11-18(26-24-17)20-19(13-6-4-3-5-7-13)15-10-14(22)8-9-16(15)23-21(20)25/h3-12H,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371930 (CHEMBL403097) Show SMILES Nc1cc(on1)-c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C18H12ClN3O2/c19-11-6-7-13-12(8-11)16(10-4-2-1-3-5-10)17(18(23)21-13)14-9-15(20)22-24-14/h1-9H,(H2,20,22)(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371933 (CHEMBL256836) Show SMILES Cc1cc([o+][n-]1)-c1c(-c2ccccc2)c2cc(ccc2[nH]c1=O)[N+]([O-])=O Show InChI InChI=1S/C19H13N3O4/c1-11-9-16(26-21-11)18-17(12-5-3-2-4-6-12)14-10-13(22(24)25)7-8-15(14)20-19(18)23/h2-10H,1H3,(H,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371918 (CHEMBL270783) Show SMILES Cc1cc(on1)-c1c(C2CCCCC2)c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C19H19ClN2O2/c1-11-9-16(24-22-11)18-17(12-5-3-2-4-6-12)14-10-13(20)7-8-15(14)21-19(18)23/h7-10,12H,2-6H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50371929 (CHEMBL257456) Show SMILES Clc1ccc2[nH]c(=O)c(-c3ccc[nH]3)c(-c3ccccc3)c2c1 Show InChI InChI=1S/C19H13ClN2O/c20-13-8-9-15-14(11-13)17(12-5-2-1-3-6-12)18(19(23)22-15)16-7-4-10-21-16/h1-11,21H,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236299 (1-(2-chlorophenylsulfonyl)-3-(2-(5-cyano-2-(4-fluo...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCNC(=O)NS(=O)(=O)c1ccccc1Cl)C#N Show InChI InChI=1S/C24H18ClFN4O3S/c25-20-3-1-2-4-22(20)34(32,33)30-24(31)28-12-11-18-19-13-15(14-27)5-10-21(19)29-23(18)16-6-8-17(26)9-7-16/h1-10,13,29H,11-12H2,(H2,28,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236306 (1-(2-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)eth...) Show SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCNC(=O)NS(=O)(=O)c1ccc(F)cc1)C#N Show InChI InChI=1S/C24H18F2N4O3S/c25-17-4-2-16(3-5-17)23-20(21-13-15(14-27)1-10-22(21)29-23)11-12-28-24(31)30-34(32,33)19-8-6-18(26)7-9-19/h1-10,13,29H,11-12H2,(H2,28,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair

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