Compile Data Set for Download or QSAR

Found 77 hits with Last Name = 'dombrovski' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164787 (CHEMBL3798088) Show SMILES CC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@](C)(CCCCNC(=O)[C@H](NC1=O)c1ccccc1)NC(=O)C(C)C |r| Show InChI InChI=1S/C29H46N8O5/c1-5-20-24(39)36-22(19-12-7-6-8-13-19)26(41)32-16-10-9-15-29(4,37-23(38)18(2)3)27(42)35-21(25(40)34-20)14-11-17-33-28(30)31/h6-8,12-13,18,20-22H,5,9-11,14-17H2,1-4H3,(H,32,41)(H,34,40)(H,35,42)(H,36,39)(H,37,38)(H4,30,31,33)/t20-,21-,22+,29+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of SUMO-His-tagged WDR5 (unknown origin) interaction with MLL1 assessed as displacement of fluorescence labelled Ac-ARA peptide substrate ...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM200712 (US9233086, 10A) Show SMILES CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C35H51N7O4/c1-5-34(6-2,41-29(43)24(3)4)31(45)39-27(20-15-23-38-33(36)37)30(44)42-35(21-13-14-22-35)32(46)40-28(25-16-9-7-10-17-25)26-18-11-8-12-19-26/h7-12,16-19,24,27-28H,5-6,13-15,20-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,43)(H,42,44)(H4,36,37,38)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged WDR5 (24 to 334 residues) (unknown origin) interaction with MLL1 assessed as displacement of 5-Lys-FAM peptide su...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase 2A (Homo sapiens (Human))	BDBM50164787 (CHEMBL3798088) Show SMILES CC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@](C)(CCCCNC(=O)[C@H](NC1=O)c1ccccc1)NC(=O)C(C)C |r| Show InChI InChI=1S/C29H46N8O5/c1-5-20-24(39)36-22(19-12-7-6-8-13-19)26(41)32-16-10-9-15-29(4,37-23(38)18(2)3)27(42)35-21(25(40)34-20)14-11-17-33-28(30)31/h6-8,12-13,18,20-22H,5,9-11,14-17H2,1-4H3,(H,32,41)(H,34,40)(H,35,42)(H,36,39)(H,37,38)(H4,30,31,33)/t20-,21-,22+,29+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of SUMO-His-tagged MLL1 activity (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS cells using histone H3 as substrate by sci...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50164770 (CHEMBL3799275) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc2ccccc2c1 Show InChI InChI=1S/C27H24F3N5O2/c1-34-8-10-35(11-9-34)24-7-6-17(19-12-18-4-2-3-5-22(18)31-15-19)13-23(24)33-26(37)20-16-32-25(36)14-21(20)27(28,29)30/h2-7,12-16H,8-11H2,1H3,(H,32,36)(H,33,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE assay in presence ...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50164770 (CHEMBL3799275) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc2ccccc2c1 Show InChI InChI=1S/C27H24F3N5O2/c1-34-8-10-35(11-9-34)24-7-6-17(19-12-18-4-2-3-5-22(18)31-15-19)13-23(24)33-26(37)20-16-32-25(36)14-21(20)27(28,29)30/h2-7,12-16H,8-11H2,1H3,(H,32,36)(H,33,37)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant FLT4 using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE assay in presence of ATP				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428255 (CHEMBL1231559) Show SMILES OC(=O)c1ccc2ccccc2c1-c1c(ccc2ccccc12)C(O)=O |(-4.26,1.44,;-3.56,.84,;-3.56,-.7,;-1.59,1.44,;-1.59,2.98,;-.26,3.75,;1.07,2.98,;2.41,3.75,;3.74,2.98,;3.74,1.44,;2.41,.67,;1.07,1.44,;-.26,.67,;-.26,-.87,;-1.59,-1.64,;-1.59,-3.18,;-.26,-3.95,;1.07,-3.18,;2.41,-3.95,;3.74,-3.18,;3.74,-1.64,;2.41,-.87,;1.07,-1.64,;-2.93,-.87,;-4.26,-1.64,;-2.93,.67,)| Show InChI InChI=1S/C22H14O4/c23-21(24)17-11-9-13-5-1-3-7-15(13)19(17)20-16-8-4-2-6-14(16)10-12-18(20)22(25)26/h1-12H,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Antagonist activity at WDR5 (unknown origin)				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase PRDM9 [195-385] (Homo sapiens (Human))	BDBM228646 (H3 (1-25) K4me0 | MARTKQTARKSTGGKAPRKQLATKA) Show SMILES CSCC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(O)=O |r| Show InChI InChI=1S/C112H205N41O33S/c1-55(2)51-76(101(177)133-58(5)89(165)149-85(63(10)157)106(182)145-67(28-14-19-42-114)92(168)136-60(7)109(185)186)147-98(174)74(36-38-79(119)159)142-93(169)68(29-15-20-43-115)140-96(172)72(33-24-47-128-111(123)124)144-103(179)78-35-26-49-153(78)108(184)59(6)135-91(167)66(27-13-18-41-113)137-82(162)53-130-81(161)52-131-104(180)83(61(8)155)150-102(178)77(54-154)148-97(173)69(30-16-21-44-116)141-95(171)71(32-23-46-127-110(121)122)138-88(164)57(4)134-105(181)84(62(9)156)151-100(176)75(37-39-80(120)160)143-94(170)70(31-17-22-45-117)146-107(183)86(64(11)158)152-99(175)73(34-25-48-129-112(125)126)139-87(163)56(3)132-90(166)65(118)40-50-187-12/h55-78,83-86,154-158H,13-54,113-118H2,1-12H3,(H2,119,159)(H2,120,160)(H,130,161)(H,131,180)(H,132,166)(H,133,177)(H,134,181)(H,135,167)(H,136,168)(H,137,162)(H,138,164)(H,139,163)(H,140,172)(H,141,171)(H,142,169)(H,143,170)(H,144,179)(H,145,182)(H,146,183)(H,147,174)(H,148,173)(H,149,165)(H,150,178)(H,151,176)(H,152,175)(H,185,186)(H4,121,122,127)(H4,123,124,128)(H4,125,126,129)/t56-,57-,58-,59-,60-,61+,62+,63+,64+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-,86-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	8.5	23
University of Toronto					Assay Description In this assay [3H]AdoMet (PerkinElmer Life Sciences; catalog number NET155V250UC)was used as a methyl donor to methylate biotinylated histone peptide...				J Biol Chem 289: 12177-88 (2014) Article DOI: 10.1074/jbc.M113.523183 BindingDB Entry DOI: 10.7270/Q2SQ8Z86
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase PRDM9 [195-385] (Homo sapiens (Human))	BDBM228648 (H3 (1-25) K4me2 | MARTKQTARKSTGGKAPRKQLATKA) Show SMILES CSCC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCC[NH+](C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(O)=O |r| Show InChI InChI=1S/C114H209N41O33S/c1-57(2)53-78(103(179)134-60(5)91(167)150-87(65(10)159)108(184)146-69(30-16-21-44-116)94(170)137-62(7)111(187)188)148-100(176)76(38-40-81(120)161)143-95(171)70(31-17-22-45-117)141-98(174)74(35-26-48-129-113(124)125)145-105(181)80-37-28-51-155(80)110(186)61(6)136-93(169)68(29-15-20-43-115)138-84(164)55-131-83(163)54-132-106(182)85(63(8)157)151-104(180)79(56-156)149-99(175)71(32-18-23-46-118)142-97(173)73(34-25-47-128-112(122)123)139-90(166)59(4)135-107(183)86(64(9)158)152-102(178)77(39-41-82(121)162)144-96(172)72(33-19-24-50-154(12)13)147-109(185)88(66(11)160)153-101(177)75(36-27-49-130-114(126)127)140-89(165)58(3)133-92(168)67(119)42-52-189-14/h57-80,85-88,156-160H,15-56,115-119H2,1-14H3,(H2,120,161)(H2,121,162)(H,131,163)(H,132,182)(H,133,168)(H,134,179)(H,135,183)(H,136,169)(H,137,170)(H,138,164)(H,139,166)(H,140,165)(H,141,174)(H,142,173)(H,143,171)(H,144,172)(H,145,181)(H,146,184)(H,147,185)(H,148,176)(H,149,175)(H,150,167)(H,151,180)(H,152,178)(H,153,177)(H,187,188)(H4,122,123,128)(H4,124,125,129)(H4,126,127,130)/p+1/t58-,59-,60-,61-,62-,63+,64+,65+,66+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,85-,86-,87-,88-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	8.5	23
University of Toronto					Assay Description In this assay [3H]AdoMet (PerkinElmer Life Sciences; catalog number NET155V250UC)was used as a methyl donor to methylate biotinylated histone peptide...				J Biol Chem 289: 12177-88 (2014) Article DOI: 10.1074/jbc.M113.523183 BindingDB Entry DOI: 10.7270/Q2SQ8Z86
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase PRDM9 [195-385] (Homo sapiens (Human))	BDBM228649 (H3 (1-25) K4me3 | MARTKQTARKSTGGKAPRKQLATKA) Show SMILES CSCC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(O)=O |r| Show InChI InChI=1S/C115H211N41O33S/c1-58(2)54-79(104(180)135-61(5)92(168)151-88(66(10)160)109(185)147-70(31-17-22-45-117)95(171)138-63(7)112(188)189)149-101(177)77(39-41-82(121)162)144-96(172)71(32-18-23-46-118)142-99(175)75(36-27-49-130-114(125)126)146-106(182)81-38-29-51-155(81)111(187)62(6)137-94(170)69(30-16-21-44-116)139-85(165)56-132-84(164)55-133-107(183)86(64(8)158)152-105(181)80(57-157)150-100(176)72(33-19-24-47-119)143-98(174)74(35-26-48-129-113(123)124)140-91(167)60(4)136-108(184)87(65(9)159)153-103(179)78(40-42-83(122)163)145-97(173)73(34-20-25-52-156(12,13)14)148-110(186)89(67(11)161)154-102(178)76(37-28-50-131-115(127)128)141-90(166)59(3)134-93(169)68(120)43-53-190-15/h58-81,86-89,157-161H,16-57,116-120H2,1-15H3,(H39-,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,149,150,151,152,153,154,162,163,164,165,166,167,168,169,170,171,172,173,174,175,176,177,178,179,180,181,182,183,184,185,186,188,189)/p+1/t59-,60-,61-,62-,63-,64+,65+,66+,67+,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,86-,87-,88-,89-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	8.5	23
University of Toronto					Assay Description In this assay [3H]AdoMet (PerkinElmer Life Sciences; catalog number NET155V250UC)was used as a methyl donor to methylate biotinylated histone peptide...				J Biol Chem 289: 12177-88 (2014) Article DOI: 10.1074/jbc.M113.523183 BindingDB Entry DOI: 10.7270/Q2SQ8Z86
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase PRDM9 [195-385] (Homo sapiens (Human))	BDBM228650 (H3 (21-44) K36me0 | LATKAARKSAPSTGGVKKPHRYRP) Show SMILES CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	8.5	23
University of Toronto					Assay Description In this assay [3H]AdoMet (PerkinElmer Life Sciences; catalog number NET155V250UC)was used as a methyl donor to methylate biotinylated histone peptide...				J Biol Chem 289: 12177-88 (2014) Article DOI: 10.1074/jbc.M113.523183 BindingDB Entry DOI: 10.7270/Q2SQ8Z86
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase PRDM9 [195-385] (Homo sapiens (Human))	BDBM228651 (H3 (21-44) K36me1 | LATKAARKSAPSTGGVKKPHRYRP) Show SMILES C[NH2+]CCCC[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	8.5	23
University of Toronto					Assay Description In this assay [3H]AdoMet (PerkinElmer Life Sciences; catalog number NET155V250UC)was used as a methyl donor to methylate biotinylated histone peptide...				J Biol Chem 289: 12177-88 (2014) Article DOI: 10.1074/jbc.M113.523183 BindingDB Entry DOI: 10.7270/Q2SQ8Z86
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase PRDM9 [195-385] (Homo sapiens (Human))	BDBM228652 (H3 (21-44) K36me2 | LATKAARKSAPSTGGVKKPHRYRP) Show SMILES CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCC[NH+](C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	8.5	23
University of Toronto					Assay Description In this assay [3H]AdoMet (PerkinElmer Life Sciences; catalog number NET155V250UC)was used as a methyl donor to methylate biotinylated histone peptide...				J Biol Chem 289: 12177-88 (2014) Article DOI: 10.1074/jbc.M113.523183 BindingDB Entry DOI: 10.7270/Q2SQ8Z86
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase PRDM9 [195-385] (Homo sapiens (Human))	BDBM228653 (H3 (21-44) K36me3 | LATKAARKSAPSTGGVKKPHRYRP) Show SMILES CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	9.60E+3	n/a	n/a	n/a	8.5	23
University of Toronto					Assay Description In this assay [3H]AdoMet (PerkinElmer Life Sciences; catalog number NET155V250UC)was used as a methyl donor to methylate biotinylated histone peptide...				J Biol Chem 289: 12177-88 (2014) Article DOI: 10.1074/jbc.M113.523183 BindingDB Entry DOI: 10.7270/Q2SQ8Z86
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164773 (CHEMBL3799127) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(N)cc1 Show InChI InChI=1S/C24H24F3N5O2/c1-31-8-10-32(11-9-31)21-7-4-16(15-2-5-17(28)6-3-15)12-20(21)30-23(34)18-14-29-22(33)13-19(18)24(25,26)27/h2-7,12-14H,8-11,28H2,1H3,(H,29,33)(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164785 (CHEMBL3797967) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnn(CCN2CCOCC2)c1 Show InChI InChI=1S/C27H32F3N7O3/c1-34-4-7-36(8-5-34)24-3-2-19(20-16-32-37(18-20)9-6-35-10-12-40-13-11-35)14-23(24)33-26(39)21-17-31-25(38)15-22(21)27(28,29)30/h2-3,14-18H,4-13H2,1H3,(H,31,38)(H,33,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428271 (CHEMBL2337032) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(C)c1Cl)[N+]([O-])=O Show InChI InChI=1S/C19H20ClFN4O3/c1-12-15(21)5-4-14(18(12)20)19(26)22-16-11-13(25(27)28)3-6-17(16)24-9-7-23(2)8-10-24/h3-6,11H,7-10H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164786 (CHEMBL3798573) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(C)c1)-c1cnc2ccccc2c1 Show InChI InChI=1S/C28H28N4O/c1-20-6-5-8-23(16-20)28(33)30-26-18-21(10-11-27(26)32-14-12-31(2)13-15-32)24-17-22-7-3-4-9-25(22)29-19-24/h3-11,16-19H,12-15H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164788 (CHEMBL3800271) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(C)cc(C)c1)[N+]([O-])=O Show InChI InChI=1S/C20H24N4O3/c1-14-10-15(2)12-16(11-14)20(25)21-18-13-17(24(26)27)4-5-19(18)23-8-6-22(3)7-9-23/h4-5,10-13H,6-9H2,1-3H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164789 (CHEMBL3798578) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(C)c(F)c(C)c1)[N+]([O-])=O Show InChI InChI=1S/C20H23FN4O3/c1-13-10-15(11-14(2)19(13)21)20(26)22-17-12-16(25(27)28)4-5-18(17)24-8-6-23(3)7-9-24/h4-5,10-12H,6-9H2,1-3H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164790 (CHEMBL3797611) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c(F)c(C)c(F)c(C)c1F)[N+]([O-])=O Show InChI InChI=1S/C20H21F3N4O3/c1-11-17(21)12(2)19(23)16(18(11)22)20(28)24-14-10-13(27(29)30)4-5-15(14)26-8-6-25(3)7-9-26/h4-5,10H,6-9H2,1-3H3,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164791 (CHEMBL3799704) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)[N+]([O-])=O Show InChI InChI=1S/C18H18F3N5O4/c1-24-4-6-25(7-5-24)15-3-2-11(26(29)30)8-14(15)23-17(28)12-10-22-16(27)9-13(12)18(19,20)21/h2-3,8-10H,4-7H2,1H3,(H,22,27)(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164792 (CHEMBL3798198) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc2OCCc2c1 Show InChI InChI=1S/C26H25F3N4O3/c1-32-7-9-33(10-8-32)22-4-2-17(16-3-5-23-18(12-16)6-11-36-23)13-21(22)31-25(35)19-15-30-24(34)14-20(19)26(27,28)29/h2-5,12-15H,6-11H2,1H3,(H,30,34)(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164770 (CHEMBL3799275) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc2ccccc2c1 Show InChI InChI=1S/C27H24F3N5O2/c1-34-8-10-35(11-9-34)24-7-6-17(19-12-18-4-2-3-5-22(18)31-15-19)13-23(24)33-26(37)20-16-32-25(36)14-21(20)27(28,29)30/h2-7,12-16H,8-11H2,1H3,(H,32,36)(H,33,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164793 (CHEMBL3799840) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C26H24F3N5O2/c1-33-8-10-34(11-9-33)23-5-3-17(16-2-4-21-18(12-16)6-7-30-21)13-22(23)32-25(36)19-15-31-24(35)14-20(19)26(27,28)29/h2-7,12-15,30H,8-11H2,1H3,(H,31,35)(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164794 (CHEMBL3798846 | US11174250, Example Table4.1.1 | U...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30,31)32/h2-6,15-18H,7-14,19H2,1H3,(H,33,38)(H,34,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164795 (CHEMBL3799608) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(NC(C)=O)nc1 Show InChI InChI=1S/C25H25F3N6O3/c1-15(35)31-22-6-4-17(13-29-22)16-3-5-21(34-9-7-33(2)8-10-34)20(11-16)32-24(37)18-14-30-23(36)12-19(18)25(26,27)28/h3-6,11-14H,7-10H2,1-2H3,(H,30,36)(H,32,37)(H,29,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50164796 (CHEMBL3800054) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(N)nc1 Show InChI InChI=1S/C23H23F3N6O2/c1-31-6-8-32(9-7-31)19-4-2-14(15-3-5-20(27)28-12-15)10-18(19)30-22(34)16-13-29-21(33)11-17(16)23(24,25)26/h2-5,10-13H,6-9H2,1H3,(H2,27,28)(H,29,33)(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
Ontario Institute for Cancer Research Curated by ChEMBL					Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...				J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428235 (CHEMBL2337028) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)cc1)[N+]([O-])=O Show InChI InChI=1S/C18H19FN4O3/c1-21-8-10-22(11-9-21)17-7-6-15(23(25)26)12-16(17)20-18(24)13-2-4-14(19)5-3-13/h2-7,12H,8-11H2,1H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428236 (CHEMBL1457864) Show SMILES COc1cccc(c1)C(=O)Nc1cc(ccc1N1CCN(C)CC1)[N+]([O-])=O Show InChI InChI=1S/C19H22N4O4/c1-21-8-10-22(11-9-21)18-7-6-15(23(25)26)13-17(18)20-19(24)14-4-3-5-16(12-14)27-2/h3-7,12-13H,8-11H2,1-2H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428237 (CHEMBL2337450) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(O)c1)[N+]([O-])=O Show InChI InChI=1S/C18H20N4O4/c1-20-7-9-21(10-8-20)17-6-5-14(22(25)26)12-16(17)19-18(24)13-3-2-4-15(23)11-13/h2-6,11-12,23H,7-10H2,1H3,(H,19,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428238 (CHEMBL2337449) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(C)c1Cl)[N+]([O-])=O Show InChI InChI=1S/C19H21ClN4O3/c1-13-4-3-5-15(18(13)20)19(25)21-16-12-14(24(26)27)6-7-17(16)23-10-8-22(2)9-11-23/h3-7,12H,8-11H2,1-2H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428239 (CHEMBL2337448) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(C)c1)[N+]([O-])=O Show InChI InChI=1S/C19H22N4O3/c1-14-4-3-5-15(12-14)19(24)20-17-13-16(23(25)26)6-7-18(17)22-10-8-21(2)9-11-22/h3-7,12-13H,8-11H2,1-2H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428240 (CHEMBL2337447) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(Cl)c1)[N+]([O-])=O Show InChI InChI=1S/C18H19ClN4O3/c1-21-7-9-22(10-8-21)17-6-5-15(23(25)26)12-16(17)20-18(24)13-3-2-4-14(19)11-13/h2-6,11-12H,7-10H2,1H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428241 (CHEMBL2337446) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(C)=O)[N+]([O-])=O Show InChI InChI=1S/C13H18N4O3/c1-10(18)14-12-9-11(17(19)20)3-4-13(12)16-7-5-15(2)6-8-16/h3-4,9H,5-8H2,1-2H3,(H,14,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428242 (CHEMBL2337445) Show SMILES CN(C)CCN(C)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C18H21ClN4O3/c1-21(2)10-11-22(3)17-9-8-13(23(25)26)12-16(17)20-18(24)14-6-4-5-7-15(14)19/h4-9,12H,10-11H2,1-3H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428243 (CHEMBL2337444) Show SMILES NC1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C18H19ClN4O3/c19-15-4-2-1-3-14(15)18(24)21-16-11-13(23(25)26)5-6-17(16)22-9-7-12(20)8-10-22/h1-6,11-12H,7-10,20H2,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428244 (CHEMBL2337443) Show SMILES NC1CCN(C1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C17H17ClN4O3/c18-14-4-2-1-3-13(14)17(23)20-15-9-12(22(24)25)5-6-16(15)21-8-7-11(19)10-21/h1-6,9,11H,7-8,10,19H2,(H,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428245 (CHEMBL2337442) Show SMILES [O-][N+](=O)c1ccc(N2CCNCC2)c(NC(=O)c2ccccc2Cl)c1 Show InChI InChI=1S/C17H17ClN4O3/c18-14-4-2-1-3-13(14)17(23)20-15-11-12(22(24)25)5-6-16(15)21-9-7-19-8-10-21/h1-6,11,19H,7-10H2,(H,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428246 (CHEMBL2337441) Show SMILES CN(C)C1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C20H23ClN4O3/c1-23(2)14-9-11-24(12-10-14)19-8-7-15(25(27)28)13-18(19)22-20(26)16-5-3-4-6-17(16)21/h3-8,13-14H,9-12H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428247 (CHEMBL2337039) Show SMILES CN(C)C1CCN(C1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C19H21ClN4O3/c1-22(2)14-9-10-23(12-14)18-8-7-13(24(26)27)11-17(18)21-19(25)15-5-3-4-6-16(15)20/h3-8,11,14H,9-10,12H2,1-2H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428248 (CHEMBL2337038) Show SMILES CCN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C19H21ClN4O3/c1-2-22-9-11-23(12-10-22)18-8-7-14(24(26)27)13-17(18)21-19(25)15-5-3-4-6-16(15)20/h3-8,13H,2,9-12H2,1H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428249 (CHEMBL2337037) Show SMILES [O-][N+](=O)c1ccc(N2CCCCC2)c(NC(=O)c2ccccc2Cl)c1 Show InChI InChI=1S/C18H18ClN3O3/c19-15-7-3-2-6-14(15)18(23)20-16-12-13(22(24)25)8-9-17(16)21-10-4-1-5-11-21/h2-3,6-9,12H,1,4-5,10-11H2,(H,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428250 (CHEMBL2337036) Show SMILES [O-][N+](=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccccc2Cl)c1 Show InChI InChI=1S/C17H16ClN3O4/c18-14-4-2-1-3-13(14)17(22)19-15-11-12(21(23)24)5-6-16(15)20-7-9-25-10-8-20/h1-6,11H,7-10H2,(H,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428251 (CHEMBL2337035) Show SMILES CN1CCCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C19H21ClN4O3/c1-22-9-4-10-23(12-11-22)18-8-7-14(24(26)27)13-17(18)21-19(25)15-5-2-3-6-16(15)20/h2-3,5-8,13H,4,9-12H2,1H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428252 (CHEMBL2337034) Show SMILES CC1CN(CCN1C)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C19H21ClN4O3/c1-13-12-23(10-9-22(13)2)18-8-7-14(24(26)27)11-17(18)21-19(25)15-5-3-4-6-16(15)20/h3-8,11,13H,9-10,12H2,1-2H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428253 (CHEMBL2337033) Show SMILES [O-][N+](=O)c1ccc(F)c(NC(=O)c2ccccc2Cl)c1 Show InChI InChI=1S/C13H8ClFN2O3/c14-10-4-2-1-3-9(10)13(18)16-12-7-8(17(19)20)5-6-11(12)15/h1-7H,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428254 (CHEMBL1609857) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C18H19ClN4O3/c1-21-8-10-22(11-9-21)17-7-6-13(23(25)26)12-16(17)20-18(24)14-4-2-3-5-15(14)19/h2-7,12H,8-11H2,1H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428254 (CHEMBL1609857) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C18H19ClN4O3/c1-21-8-10-22(11-9-21)17-7-6-13(23(25)26)12-16(17)20-18(24)14-4-2-3-5-15(14)19/h2-7,12H,8-11H2,1H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of MLL-WIN N-terminal FITC-tagged GSARAEVHLRKS peptide from human WDR5 (1-334) by fluorescence polarization assay				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428256 (CHEMBL2337027) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)-c1ccncc1 Show InChI InChI=1S/C23H23ClN4O/c1-27-12-14-28(15-13-27)22-7-6-18(17-8-10-25-11-9-17)16-21(22)26-23(29)19-4-2-3-5-20(19)24/h2-11,16H,12-15H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50428257 (CHEMBL2337026) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)-c1ccco1 Show InChI InChI=1S/C22H22ClN3O2/c1-25-10-12-26(13-11-25)20-9-8-16(21-7-4-14-28-21)15-19(20)24-22(27)17-5-2-3-6-18(17)23/h2-9,14-15H,10-13H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair

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