Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209049 (US9243038, 26) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209051 (US9243038, 27) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209041 (US9243038, 15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209054 (US9243038, 13) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209053 (US9243038, 8) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209032 (US9243038, 6a (cis olefin) | US9243038, 6b (trans ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314096 (US9610322, 6b (trans olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209045 (US9243038, 20) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209048 (US9243038, 28) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209046 (US9243038, 21) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Mus musculus (Mouse)) | BDBM209032 (US9243038, 6a (cis olefin) | US9243038, 6b (trans ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Mus musculus (Mouse)) | BDBM209045 (US9243038, 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209052 (US9243038, 29) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209024 (US9243038, 2a (cis olefin) | US9243038, 2b (trans ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209042 (US9243038, 16) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209043 (US9243038, 17) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209034 (US9243038, 6c ) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209025 (US9243038, 5a (cis olefin) | US9243038, 5b (trans ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314094 (US9610322, 5b (trans olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209027 (US9243038, 3b (trans olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209037 (US9243038, 10) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314089 (US9610322, 3b (trans olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209038 (US9243038, 11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209044 (US9243038, 19) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209050 (US9243038, 25) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209032 (US9243038, 6a (cis olefin) | US9243038, 6b (trans ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314095 (US9610322, 6a (cis olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209036 (US9243038, 9) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209047 (US9243038, 24) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314087 (US9610322, 2 (cis olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209035 (US9243038, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209039 (US9243038, 12) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209024 (US9243038, 2a (cis olefin) | US9243038, 2b (trans ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209026 (US9243038, 3a (cis olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209025 (US9243038, 5a (cis olefin) | US9243038, 5b (trans ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM60940 (US9243038, 18 | US9243038, 23) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209040 (US9243038, 14) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314093 (US9610322, 5a (cis olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314088 (US9610322, 3a (cis olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314090 (US9610322, 4a (cis olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314092 (US9610322, 4b (trans olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209028 (US9243038, 4a (cis olefin) | US9243038, 4b (trans ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209023 (US9243038, 1 (cis olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM209028 (US9243038, 4a (cis olefin) | US9243038, 4b (trans ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM314086 (US9610322, 1 (cis olefin)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N... | US Patent US9610322 (2017) BindingDB Entry DOI: 10.7270/Q29Z970C | |||||||||||
More data for this Ligand-Target Pair |