Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210610![]() (CHEMBL395623 | N-(4-chlorobenzyl)-2-(((2-(benzofur...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222924![]() (US9315499, 6011) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222906![]() (US9315499, 4012) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210598![]() ((S)-N-(4-chlorobenzyl)-2-(((2-hydroxypropyl)(methy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210588![]() ((R)-N-(4-chlorobenzyl)-2-(((2-hydroxy-2-(pyrazin-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222899![]() (US9315499, 3019) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222915![]() (US9315499, 4062) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 59 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210609![]() ((R)-N-(3-chlorobenzyl)-2-(((2-hydroxy-2-(pyridin-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222903![]() (US9315499, 3038) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 62 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210594![]() (CHEMBL247355 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222905![]() (US9315499, 4005) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 65 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222909![]() (US9315499, 4020) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 65 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210615![]() (CHEMBL247554 | N-(4-chlorobenzyl)-2-(((2-(3-cyanop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...) | BDBM50172517![]() (4-Hydroxy-6-(3-hydroxy-propyl)-quinoline-3-carboxy...) | UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ... | J Med Chem 48: 5794-804 (2005) Article DOI: 10.1021/jm050162b BindingDB Entry DOI: 10.7270/Q2G44R39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222901![]() (US9315499, 3027) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 71 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222910![]() (US9315499, 4024) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 74 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222926![]() (US9315499, 6017) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 77 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210620![]() (CHEMBL247148 | N-(4-chlorobenzyl)-2-(((2-(furan-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222928![]() (US9315499, 6022) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 83 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210586![]() (CHEMBL247752 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210601![]() (CHEMBL246525 | N-(3-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210616![]() (CHEMBL247556 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210611![]() (CHEMBL247751 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210612![]() (CHEMBL245291 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210617![]() ((S)-N-(4-chlorobenzyl)-2-(((2-hydroxy-2-phenylethy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210606![]() (CHEMBL396572 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222925![]() (US9315499, 6012) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 110 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222911![]() (US9315499, 4034) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222922![]() (US9315499, 6005) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222919![]() (US9315499, 5015) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222913![]() (US9315499, 4040) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 130 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222921![]() (US9315499, 6003) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 140 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210595![]() (CHEMBL246732 | N-(3-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222927![]() (US9315499, 6018) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 160 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222914![]() (US9315499, 4056) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 170 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210614![]() (CHEMBL247357 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222923![]() (US9315499, 6008) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222907![]() (US9315499, 4017) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210592![]() (CHEMBL247956 | N-(4-chlorobenzyl)-2-(((2-(furan-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222908![]() (US9315499, 4018) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 190 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222898![]() (US9315499, 3008) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222902![]() (US9315499, 3034) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210608![]() (CHEMBL246939 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210619![]() (CHEMBL394970 | N-(4-chlorobenzyl)-7-ethyl-2-(((2-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210603![]() (CHEMBL246524 | N-(3-chlorobenzyl)-2-(((2-(4-fluoro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 203 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222929![]() (US9315499, 7002) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 210 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human herpesvirus 1 (strain KOS) (HHV-1) (Human he...) | BDBM50251807![]() ((R)-N-(4-chlorobenzyl)-2-(((2-(furan-2-yl)-2-hydro...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HSV1 DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 18: 3856-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.060 BindingDB Entry DOI: 10.7270/Q2RB75HB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210600![]() (CHEMBL246523 | N-(4-fluorobenzyl)-2-(((2-(4-fluoro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM222890![]() (US9315499, 1008) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 220 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235... | US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) ) | BDBM50210607![]() (CHEMBL247750 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 235 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of HCMV DNA polymerase by scintillation proximity assay | Bioorg Med Chem Lett 17: 3349-53 (2007) Article DOI: 10.1016/j.bmcl.2007.03.102 BindingDB Entry DOI: 10.7270/Q2HX1DHN | |||||||||||
More data for this Ligand-Target Pair |
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