Compile Data Set for Download or QSAR

Found 80 hits Enz. Inhib. hit(s) with Target = 'Lutropin-choriogonadotropic hormone receptor' AND taxid = 9606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50206401 (CHEMBL246321 | N-((S)-1-amino-3-(4-hydroxyphenyl)-...) Show SMILES CC(C)(C)c1ccc(cc1)-n1nc(cc1CCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)-c1cccnc1 Show InChI InChI=1S/C32H37N5O3/c1-32(2,3)24-12-14-25(15-13-24)37-26(20-28(36-37)23-7-6-18-34-21-23)8-4-5-9-30(39)35-29(31(33)40)19-22-10-16-27(38)17-11-22/h6-7,10-18,20-21,29,38H,4-5,8-9,19H2,1-3H3,(H2,33,40)(H,35,39)/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.311	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Geneva Research Center Curated by ChEMBL					Assay Description Displacement of [125I]-hCG from LH receptor				Bioorg Med Chem Lett 17: 2080-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.062 BindingDB Entry DOI: 10.7270/Q2VQ32B2
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505809 (CHEMBL4460075) Show SMILES Fc1ccc(NC(=O)N2CCc3sccc3C2c2ccc(Cl)cc2)cc1OC(F)(F)F Show InChI InChI=1S/C21H15ClF4N2O2S/c22-13-3-1-12(2-4-13)19-15-8-10-31-18(15)7-9-28(19)20(29)27-14-5-6-16(23)17(11-14)30-21(24,25)26/h1-6,8,10-11,19H,7,9H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50383229 (CHEMBL2032175) Show SMILES Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C20H17ClN2OS/c21-15-8-6-14(7-9-15)19-17-11-13-25-18(17)10-12-23(19)20(24)22-16-4-2-1-3-5-16/h1-9,11,13,19H,10,12H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505791 (CHEMBL4587440) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(F)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21F2N3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505799 (CHEMBL4573509) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C21H19ClN2O2S/c1-26-17-8-2-14(3-9-17)20-18-11-13-27-19(18)10-12-24(20)21(25)23-16-6-4-15(22)5-7-16/h2-9,11,13,20H,10,12H2,1H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505796 (CHEMBL4531781) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4sccc4C3c3ccc(Cl)cc3)cc2)cc1 Show InChI InChI=1S/C26H20ClFN2O2S/c27-18-3-1-17(2-4-18)25-23-14-16-33-24(23)13-15-30(25)26(31)29-20-7-11-22(12-8-20)32-21-9-5-19(28)6-10-21/h1-12,14,16,25H,13,15H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505785 (CHEMBL4443605) Show SMILES Fc1ccc(NC(=O)N2CCc3sccc3C2c2ccc(Cl)cc2)cc1Cl Show InChI InChI=1S/C20H15Cl2FN2OS/c21-13-3-1-12(2-4-13)19-15-8-10-27-18(15)7-9-25(19)20(26)24-14-5-6-17(23)16(22)11-14/h1-6,8,10-11,19H,7,9H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505783 (CHEMBL4458424) Show SMILES Fc1ccc(Oc2ncc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(F)cc3)cn2)cc1 |r| Show InChI InChI=1S/C25H19F2N5O2/c26-17-5-3-16(4-6-17)23-21-2-1-12-28-22(21)11-13-32(23)25(33)31-19-14-29-24(30-15-19)34-20-9-7-18(27)8-10-20/h1-10,12,14-15,23H,11,13H2,(H,31,33)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505811 (CHEMBL4461980) Show SMILES COc1cc(NC(=O)N2CCc3sccc3[C@@H]2c2ccccc2)cc(OC)c1 |r| Show InChI InChI=1S/C22H22N2O3S/c1-26-17-12-16(13-18(14-17)27-2)23-22(25)24-10-8-20-19(9-11-28-20)21(24)15-6-4-3-5-7-15/h3-7,9,11-14,21H,8,10H2,1-2H3,(H,23,25)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505797 (CHEMBL4522381) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(OC)cc(OC)c1 Show InChI InChI=1S/C23H24N2O4S/c1-27-17-6-4-15(5-7-17)22-20-9-11-30-21(20)8-10-25(22)23(26)24-16-12-18(28-2)14-19(13-16)29-3/h4-7,9,11-14,22H,8,10H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	207	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505798 (CHEMBL4581889) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C21H19ClN2O2S/c1-26-17-7-5-14(6-8-17)20-18-10-12-27-19(18)9-11-24(20)21(25)23-16-4-2-3-15(22)13-16/h2-8,10,12-13,20H,9,11H2,1H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505812 (CHEMBL4555151) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(F)cc3)cn2)cc1 |r| Show InChI InChI=1S/C26H20F2N4O2/c27-18-5-3-17(4-6-18)25-22-2-1-14-29-23(22)13-15-32(25)26(33)31-20-9-12-24(30-16-20)34-21-10-7-19(28)8-11-21/h1-12,14,16,25H,13,15H2,(H,31,33)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	312	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505795 (CHEMBL4579421) Show SMILES Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C26H21ClN2O2S/c27-19-11-9-18(10-12-19)25-23-14-16-32-24(23)13-15-29(25)26(30)28-20-5-4-8-22(17-20)31-21-6-2-1-3-7-21/h1-12,14,16-17,25H,13,15H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505793 (CHEMBL4593222) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505789 (CHEMBL4471621) Show SMILES COc1ccc(cc1)[C@@H]1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	403	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505804 (CHEMBL4590976) Show SMILES Clc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H15Cl3N2OS/c21-13-3-1-12(2-4-13)19-17-6-8-27-18(17)5-7-25(19)20(26)24-16-10-14(22)9-15(23)11-16/h1-4,6,8-11,19H,5,7H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	486	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505813 (CHEMBL4580951) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(C)cc(C)c1 Show InChI InChI=1S/C23H24N2O2S/c1-15-12-16(2)14-18(13-15)24-23(26)25-10-8-21-20(9-11-28-21)22(25)17-4-6-19(27-3)7-5-17/h4-7,9,11-14,22H,8,10H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505786 (CHEMBL4560733) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccccc2)c1 Show InChI InChI=1S/C20H16Cl2N2OS/c21-14-10-15(22)12-16(11-14)23-20(25)24-8-6-18-17(7-9-26-18)19(24)13-4-2-1-3-5-13/h1-5,7,9-12,19H,6,8H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505794 (CHEMBL4456365) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(F)c(c1)C(N)=O Show InChI InChI=1S/C22H20FN3O3S/c1-29-15-5-2-13(3-6-15)20-16-9-11-30-19(16)8-10-26(20)22(28)25-14-4-7-18(23)17(12-14)21(24)27/h2-7,9,11-12,20H,8,10H2,1H3,(H2,24,27)(H,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in Org 43553-induced agonist activity preincubated for 20 ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505808 (CHEMBL4464604) Show SMILES Fc1ccc(cc1F)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H14Cl2F2N2OS/c21-12-8-13(22)10-14(9-12)25-20(27)26-5-3-18-15(4-6-28-18)19(26)11-1-2-16(23)17(24)7-11/h1-2,4,6-10,19H,3,5H2,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50256858 (CHEMBL474041 | Cyclopentyl-carbamic acid [1,1',3',...) Show SMILES O=C(NC1CCCC1)Oc1cc(cc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C24H23NO2/c26-24(25-22-13-7-8-14-22)27-23-16-20(18-9-3-1-4-10-18)15-21(17-23)19-11-5-2-6-12-19/h1-6,9-12,15-17,22H,7-8,13-14H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]Org43553 from human luteinizing hormone receptor expressed in CHOK1 cells				J Med Chem 52: 2036-42 (2009) Article DOI: 10.1021/jm801561h BindingDB Entry DOI: 10.7270/Q2G73DMJ
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505810 (CHEMBL4551301) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccc(=O)[nH]c2)c1 Show InChI InChI=1S/C19H15Cl2N3O2S/c20-12-7-13(21)9-14(8-12)23-19(26)24-5-3-16-15(4-6-27-16)18(24)11-1-2-17(25)22-10-11/h1-2,4,6-10,18H,3,5H2,(H,22,25)(H,23,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505787 (CHEMBL4537998) Show SMILES Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1 |r| Show InChI InChI=1S/C27H21ClFN3O2/c28-19-5-3-18(4-6-19)26-24-2-1-16-30-25(24)15-17-32(26)27(33)31-21-9-13-23(14-10-21)34-22-11-7-20(29)8-12-22/h1-14,16,26H,15,17H2,(H,31,33)/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Negative allosteric modulation of human luteinizing hormone receptor assessed as reduction in glycoprotein human luteinizing hormone-induced agonist ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505802 (CHEMBL4468163) Show SMILES Cc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H18Cl2N2OS/c1-13-2-4-14(5-3-13)20-18-7-9-27-19(18)6-8-25(20)21(26)24-17-11-15(22)10-16(23)12-17/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505800 (CHEMBL4588196) Show SMILES Fc1cccc(c1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H15Cl2FN2OS/c21-13-9-14(22)11-16(10-13)24-20(26)25-6-4-18-17(5-7-27-18)19(25)12-2-1-3-15(23)8-12/h1-3,5,7-11,19H,4,6H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505801 (CHEMBL4570127) Show SMILES Fc1ccccc1C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H15Cl2FN2OS/c21-12-9-13(22)11-14(10-12)24-20(26)25-7-5-18-16(6-8-27-18)19(25)15-3-1-2-4-17(15)23/h1-4,6,8-11,19H,5,7H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505792 (CHEMBL4471875) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=S)Nc1cc(OC)cc(OC)c1 Show InChI InChI=1S/C23H24N2O3S2/c1-26-17-6-4-15(5-7-17)22-20-9-11-30-21(20)8-10-25(22)23(29)24-16-12-18(27-2)14-19(13-16)28-3/h4-7,9,11-14,22H,8,10H2,1-3H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505815 (CHEMBL4468307) Show SMILES FC(F)(F)c1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H15Cl2F3N2OS/c22-14-9-15(23)11-16(10-14)27-20(29)28-7-5-18-17(6-8-30-18)19(28)12-1-3-13(4-2-12)21(24,25)26/h1-4,6,8-11,19H,5,7H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505816 (CHEMBL4573451) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccncc2)c1 Show InChI InChI=1S/C19H15Cl2N3OS/c20-13-9-14(21)11-15(10-13)23-19(25)24-7-3-17-16(4-8-26-17)18(24)12-1-5-22-6-2-12/h1-2,4-6,8-11,18H,3,7H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505788 (CHEMBL4449797) Show SMILES COc1ccc(cc1)[C@H]1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C21H18Cl2N2O2S/c1-27-17-4-2-13(3-5-17)20-18-7-9-28-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505806 (CHEMBL4471103) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2cccnc2)c1 Show InChI InChI=1S/C19H15Cl2N3OS/c20-13-8-14(21)10-15(9-13)23-19(25)24-6-3-17-16(4-7-26-17)18(24)12-2-1-5-22-11-12/h1-2,4-5,7-11,18H,3,6H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505790 (CHEMBL4553576) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Cc1cc(C)cc(C)c1 Show InChI InChI=1S/C24H25NO2S/c1-16-12-17(2)14-18(13-16)15-23(26)25-10-8-22-21(9-11-28-22)24(25)19-4-6-20(27-3)7-5-19/h4-7,9,11-14,24H,8,10,15H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505807 (CHEMBL4463418) Show SMILES Cc1ccccc1C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H18Cl2N2OS/c1-13-4-2-3-5-17(13)20-18-7-9-27-19(18)6-8-25(20)21(26)24-16-11-14(22)10-15(23)12-16/h2-5,7,9-12,20H,6,8H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505805 (CHEMBL4563783) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCc3sccc3C2c2ccccn2)c1 Show InChI InChI=1S/C19H15Cl2N3OS/c20-12-9-13(21)11-14(10-12)23-19(25)24-7-4-17-15(5-8-26-17)18(24)16-3-1-2-6-22-16/h1-3,5-6,8-11,18H,4,7H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505803 (CHEMBL4524393) Show SMILES CC(C)c1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C23H22Cl2N2OS/c1-14(2)15-3-5-16(6-4-15)22-20-8-10-29-21(20)7-9-27(22)23(28)26-19-12-17(24)11-18(25)13-19/h3-6,8,10-14,22H,7,9H2,1-2H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505814 (CHEMBL4458027) Show SMILES NC(=O)c1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H17Cl2N3O2S/c22-14-9-15(23)11-16(10-14)25-21(28)26-7-5-18-17(6-8-29-18)19(26)12-1-3-13(4-2-12)20(24)27/h1-4,6,8-11,19H,5,7H2,(H2,24,27)(H,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50505784 (CHEMBL4464888) Show SMILES COc1ccc(cc1)C1N(CCc2sccc12)C(=O)Nc1ccc(F)c(c1)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C25H26FN3O4S2/c1-33-19-5-2-17(3-6-19)24-20-9-13-34-23(20)8-10-29(24)25(30)27-18-4-7-21(26)22(16-18)28-11-14-35(31,32)15-12-28/h2-7,9,13,16,24H,8,10-12,14-15H2,1H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...				J Med Chem 62: 10321-10341 (2019) Article DOI: 10.1021/acs.jmedchem.9b01382 BindingDB Entry DOI: 10.7270/Q29P34X6
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50189779 (CHEMBL377399 | N-tert-butyl-5-amino-4-(3-methoxyph...) Show SMILES COc1cccc(c1)-c1nc(SC)nc2sc(C(=O)N(C)C(C)(C)C)c(N)c12 Show InChI InChI=1S/C20H24N4O2S2/c1-20(2,3)24(4)18(25)16-14(21)13-15(11-8-7-9-12(10-11)26-5)22-19(27-6)23-17(13)28-16/h7-10H,21H2,1-6H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulation				J Med Chem 49: 3888-96 (2006) Article DOI: 10.1021/jm060247s BindingDB Entry DOI: 10.7270/Q29886MR
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50206403 (CHEMBL269261 | N-((S)-1-amino-3-(4-tert-butoxyphen...) Show SMILES CC(C)(C)Oc1ccc(C[C@H](NC(=O)CCCCNc2cc(nn2-c2ccc(cc2)C(C)(C)C)-c2cccnc2)C(N)=O)cc1 Show InChI InChI=1S/C36H46N6O3/c1-35(2,3)27-14-16-28(17-15-27)42-32(23-30(41-42)26-10-9-20-38-24-26)39-21-8-7-11-33(43)40-31(34(37)44)22-25-12-18-29(19-13-25)45-36(4,5)6/h9-10,12-20,23-24,31,39H,7-8,11,21-22H2,1-6H3,(H2,37,44)(H,40,43)/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a
Merck Serono Geneva Research Center Curated by ChEMBL					Assay Description Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPA				Bioorg Med Chem Lett 17: 2080-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.062 BindingDB Entry DOI: 10.7270/Q2VQ32B2
					More data for this Ligand-Target Pair
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50206404 ((S)-N-(1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-y...) Show SMILES CC(C)(C)c1ccc(cc1)-n1nc(cc1NCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)-c1ccncc1 Show InChI InChI=1S/C31H36N6O3/c1-31(2,3)23-8-10-24(11-9-23)37-28(20-26(36-37)22-14-17-33-18-15-22)34-16-4-5-29(39)35-27(30(32)40)19-21-6-12-25(38)13-7-21/h6-15,17-18,20,27,34,38H,4-5,16,19H2,1-3H3,(H2,32,40)(H,35,39)/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Merck Serono Geneva Research Center Curated by ChEMBL					Assay Description Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPA				Bioorg Med Chem Lett 17: 2080-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.062 BindingDB Entry DOI: 10.7270/Q2VQ32B2
					More data for this Ligand-Target Pair

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