Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24206 (2-{4-[2-(azepan-1-yl)ethoxy]phenoxy}-1,3-benzoxazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24216 (1-{2-[4-(1,3-benzoxazol-2-yloxy)phenoxy]ethyl}-4-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24199 (2-{4-[2-(pyrrolidin-1-yl)ethoxy]phenoxy}-1,3-benzo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24224 (1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}pip...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24238 (Benzthiazole compound, 33p | N-(1-{[4-(1,3-benzoth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24212 (1-{2-[4-(1,3-benzoxazol-2-yloxy)phenoxy]ethyl}pipe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24235 (3-(1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24203 (2-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1,3-benzox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24239 (1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}pipe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24222 (3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24236 (Benzthiazole compound, 33n | N-(1-{[4-(1,3-benzoth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24234 (1-(1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24227 (1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24218 (1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}pi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24215 ((1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24214 ((1-{2-[4-(1,3-benzoxazol-2-yloxy)phenoxy]ethyl}pip...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24201 (2-{4-[2-(pyrrolidin-1-yl)ethoxy]phenoxy}-1,3-benzo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24220 (1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24223 (2-{4-[2-(piperidin-1-yl)ethyl]phenoxy}-1,3-benzoth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24233 (1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}pipe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24237 (Benzthiazole compound, 33o | [(1-{[4-(1,3-benzothi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24240 (2-{4-[3-(piperidin-1-yl)propoxy]phenoxy}-1,3-benzo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24225 (1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}pip...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24228 (3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24213 (1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}pi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24232 (1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}pipe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24229 (Benzthiazole compound, 27n | N-(1-{2-[4-(1,3-benzo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24230 (Benzthiazole compound, 27o | [(1-{2-[4-(1,3-benzot...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24204 (2-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1,3-benzot...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24209 (2-{4-[2-(morpholin-4-yl)ethoxy]phenoxy}-1,3-benzox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 58 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24231 (2-[4-(piperidin-1-ylmethyl)phenoxy]-1,3-benzothiaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24219 (1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}pi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24207 (2-{4-[2-(azepan-1-yl)ethoxy]phenoxy}-1,3-benzothia...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24217 (1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24221 (1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24202 (2-{4-[2-(pyrrolidin-1-yl)ethoxy]phenoxy}-1H-1,3-be...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 84 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24241 (2-{4-[3-(piperidin-1-yl)propoxy]phenoxy}-1,3-benzo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24205 (2-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1H-1,3-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24208 (2-{4-[2-(azepan-1-yl)ethoxy]phenoxy}-1H-1,3-benzod...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24210 (4-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl}mo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM24228 (3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical | Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24242 (2-{4-[3-(piperidin-1-yl)propoxy]phenoxy}-1H-1,3-be...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM24203 (2-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1,3-benzox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM24227 (1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical | Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM24221 (1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM24223 (2-{4-[2-(piperidin-1-yl)ethyl]phenoxy}-1,3-benzoth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM24222 (3-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM24220 (1-(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenoxy]ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM24211 (4-{2-[4-(1H-1,3-benzodiazol-2-yloxy)phenoxy]ethyl}...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,... | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM24224 (1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}pip...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel. | J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX | |||||||||||
More data for this Ligand-Target Pair |
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