Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31801 (2-aminobenzimidazole deriv., 12) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | 7 | -46.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31800 (2-aminobenzimidazole deriv., 11) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 47 | -41.5 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303504 (2,4-diamino-6,7-diisopropylpteridin-1-ium | 6,7-bi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31798 (2-aminobenzimidazole deriv., 9) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 400 | -36.3 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31799 (2-aminobenzimidazole deriv., 10) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 510 | -35.7 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303518 (2,4-diamino-6-(benzylthio)pyrimidin-1-ium | 6-(ben...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303514 (2-amino-6-(1,3-benzodioxol-5-yl)-4-oxo-4,7-dihydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303519 (6-[(4'-Methoxybenzyl)sulfanyl]-2,4-pyrimidinediami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303512 (2-amino-6-(4-methoxyphenyl)-4-oxo-4,7-dihydro-3H-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM6644 (6‐phenylpteridine‐2,4,7‐triamine...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303513 (2-amino-6-(3-formylphenyl)-4-oxo-4,7-dihydro-3H-py...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31795 (2-aminobenzimidazole deriv., 6) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 9.80E+3 | -28.4 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31794 (2-aminobenzimidazole deriv., 4 | 5-Chloro-1H-benzo...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 1.06E+4 | -28.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303505 (6,7,7-trimethyl-7,8-dihydropteridine-2,4-diamine |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | Article PubMed | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303511 (2-amino-6-(4-ethylphenyl)-4-oxo-4,7-dihydro-3H-pyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31791 (2-aminobenzothiazole deriv., 2) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 2.11E+4 | -26.5 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31797 (2-aminobenzimidazole deriv., 8) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 2.39E+4 | -26.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303508 (2-amino-5-(2-phenylethyl)-3,7-dihydro-4H-pyrrolo[2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303517 (2,4-diamino-6-(p-tolylthio)pyrimidin-1-ium | 6-[(4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303516 (2,4-diamino-6-(cyclopropylamino)pyrimidin-1-ium | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303506 (2-amino-3H-pyrrolo[2,3-d]pyrimidine-4(7H)-thione |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50028122 (2-Amino-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303509 (2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | Article PubMed | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303510 (2-amino-4-oxo-6-phenyl-4,7-dihydro-3H-pyrrolo[2,3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303507 (2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem | Article PubMed | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase 1 (Leishmania major) | BDBM50303515 (2,4,6-triaminopyrimidin-1-ium | CHEMBL571518 | PYR...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant PTR1 | J Med Chem 53: 221-9 (2010) Article DOI: 10.1021/jm901059x BindingDB Entry DOI: 10.7270/Q2H132XP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31793 (2-aminobenzothiazole deriv., 3) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.41E+5 | -21.8 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM31796 (2-aminobenzimidazole deriv., 7) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >2.00E+5 | >-21.0 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Pteridine reductase (Trypanosoma brucei brucei) | BDBM7960 (1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | 2.88E+5 | -20.1 | n/a | n/a | n/a | n/a | n/a | 6.0 | 23 |
University of Dundee | Assay Description TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob... | J Med Chem 52: 4454-65 (2009) Article DOI: 10.1021/jm900414x BindingDB Entry DOI: 10.7270/Q28050X3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50270350 (2,5-Anhydro-1-deoxy-1-(3,4-dichlorobenzylamino)-D-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei phosphofructokinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270352 ((2S,3S,4S,5R)-N-cycloheptyl-5-((cycloheptylamino)m...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50270447 ((2S,3S,4S,5R)-N-(3,4-dichlorobenzyl)-5-((cyclohept...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei phosphofructokinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50270348 ((2S,3S,4S,5R)-5-((3,4-dichlorobenzylamino)methyl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei phosphofructokinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270448 ((2S,3S,4S,5R)-5-((cycloheptylamino)methyl)-3,4-dih...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270344 (2,5-Anhydro-1-deoxy-1-(cycloheptylamino)-D-mannito...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50270351 ((2S,3S,4S,5R)-5-((3,4-dichlorobenzylamino)methyl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei phosphofructokinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50270460 (2,5-Anhydro-1-deoxy-1-(3,4-dichlorobenzylamino)-D-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei phosphofructokinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270341 ((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((R)-1-(4-metho...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270338 ((2R,3S,4S,5R)-2-(hydroxymethyl)-5-((1,2,3,4-tetrah...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270349 ((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((R)-1-(naphtha...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270347 ((2R,3S,4S,5R)-2-(((1R,2S,4R)-bicyclo[2.2.1]heptan-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270343 ((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-1-(naphtha...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270345 ((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-3-methylbu...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270474 ((2R,3S,4S,5R)-2-(hydroxymethyl)-5-((pentan-2-ylami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270340 ((2R,3S,4S,5R)-2-(hydroxymethyl)-5-(((S)-1-(4-metho...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270449 ((2R,3S,4S,5R)-2-((cyclopentylamino)methyl)-5-(hydr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.10E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pyruvate kinase (Leishmania mexicana) | BDBM50270339 ((2R,3S,4S,5R)-2-((cyclobutylamino)methyl)-5-(hydro...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of Leishmania mexicana pyruvate kinase | Bioorg Med Chem 16: 5050-61 (2008) Article DOI: 10.1016/j.bmc.2008.03.045 BindingDB Entry DOI: 10.7270/Q21J99JR | |||||||||||
More data for this Ligand-Target Pair |