Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146058 (Benzo[de]isochromene-1,3-dione | CHEMBL316059) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146048 (2,3-Dihydro-1H-naphtho[2,1-b]oxepin-4-one | CHEMBL...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146067 (1,2-Dihydro-benzo[f]thiochromen-3-one | CHEMBL3143...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146052 (5-Benzyloxy-1,2-dihydro-benzo[f]chromen-3-one | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146063 (2-Isobutyl-1,2-dihydro-benzo[f]chromen-3-one | CHE...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146044 (2-Allyl-1,2-dihydro-benzo[f]chromen-3-one | CHEMBL...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50177984 (CHEMBL372375 | para-Sirtinol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL | Assay Description Inhibitory activity against recombinant yeast Sir2 | J Med Chem 48: 7789-95 (2005) Article DOI: 10.1021/jm050100l BindingDB Entry DOI: 10.7270/Q26M36DP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146068 (7-Methoxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146062 (9-Methoxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146046 (1-Phenyl-1,2-dihydro-benzo[f]chromen-3-one | 1-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146069 (6-Methoxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50156760 ((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL | Assay Description Inhibitory activity against recombinant yeast Sir2 | J Med Chem 48: 7789-95 (2005) Article DOI: 10.1021/jm050100l BindingDB Entry DOI: 10.7270/Q26M36DP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM27507 (3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | <5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Guru Jambheshwar University of Science and Technology Curated by ChEMBL | Assay Description Non-competitive inhibition of recombinant yeast glutathione-S-transferase-tagged SIRT2 using acetylated histone as substrate measured after 30 mins b... | Eur J Med Chem 119: 45-69 (2016) Article DOI: 10.1016/j.ejmech.2016.04.063 BindingDB Entry DOI: 10.7270/Q2VH5QTW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146054 (2-Methyl-1,2-dihydro-benzo[f]chromen-3-one | CHEMB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146060 (1H-Naphtho[2,1-b]furan-2-one | CHEMBL314020) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM29590 (1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one | CHEMBL8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Hyderabad Campus Curated by ChEMBL | Assay Description Inhibition of yeast Sir 2 protein | Bioorg Med Chem Lett 23: 1351-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.089 BindingDB Entry DOI: 10.7270/Q2MW2JH8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50177983 ((R)-sirtinol | CHEMBL198582) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL | Assay Description Inhibitory activity against recombinant yeast Sir2 | J Med Chem 48: 7789-95 (2005) Article DOI: 10.1021/jm050100l BindingDB Entry DOI: 10.7270/Q26M36DP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146047 (3,4-Dihydro-benzo[h]chromen-2-one | CHEMBL91528) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50177986 ((S)-sirtinol | CHEMBL197282) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL | Assay Description Inhibitory activity against recombinant yeast Sir2 | J Med Chem 48: 7789-95 (2005) Article DOI: 10.1021/jm050100l BindingDB Entry DOI: 10.7270/Q26M36DP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50156760 ((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Guru Jambheshwar University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of recombinant yeast Sir2p using acetylated HeLa histones as substrate measured after 2 hrs in presence of NAD by scintillation counting m... | Eur J Med Chem 119: 45-69 (2016) Article DOI: 10.1016/j.ejmech.2016.04.063 BindingDB Entry DOI: 10.7270/Q2VH5QTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146050 (3,4,9,10-Tetrahydro-1,7-dioxa-chrysene-2,8-dione |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50177985 (CHEMBL200762 | meta-Sirtinol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL | Assay Description Inhibitory activity against recombinant yeast Sir2 | J Med Chem 48: 7789-95 (2005) Article DOI: 10.1021/jm050100l BindingDB Entry DOI: 10.7270/Q26M36DP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146064 (8-Methoxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM29590 (1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one | CHEMBL8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146059 (3,4-Dihydro-2H-phenanthren-1-one | CHEMBL88130) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146053 (Benzo[f]chromen-3-one | CHEMBL424248) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146061 (CHEMBL89585 | {2-[2-(3-Oxo-2,3-dihydro-1H-benzo[f]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146049 (3,4,9,10-Tetrahydro-1,12-dioxa-triphenylene-2,11-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146066 (3-(2-Hydroxy-naphthalen-1-yl)-propionic acid methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146056 (5-Hydroxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.11E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146070 (1,2-benzodihydropyrone | 2-chromanone | 2-hydroxyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146065 (3-(2-Hydroxy-naphthalen-1-yl)-propionamide | CHEMB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146057 (CHEMBL313262 | N,N-Diethyl-3-(2-hydroxy-naphthalen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146055 (5-Methoxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.28E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146051 (6-Hydroxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50146045 (9-Hydroxy-1,2-dihydro-benzo[f]chromen-3-one | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fred Hutchinson Cancer Research Center Curated by ChEMBL | Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B | |||||||||||
More data for this Ligand-Target Pair |