Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118338 (US8653111, 62) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105221 (US8580778, 21) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105220 (US8580778, 20) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105219 (US8580778, 17) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105224 (US8580778, 29) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105222 (US8580778, 25) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3527 (US8524699, 18) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118341 (US8653111, 85) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109268 (US8609698, 10) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118328 (US8653111, 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118344 (US8653111, 103) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118346 (US8653111, 129) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105223 (US8580778, 26) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3543 (US8524699, 16) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 480 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118339 (US8653111, 72) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118329 (US8653111, 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105217 (US8580778, 5) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118331 (US8653111, 17) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118347 (US8653111, 166) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3555 (US8524699, 3) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 700 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118345 (US8653111, 113) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118330 (US8653111, 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105218 (US8580778, 9) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118333 (US8653111, 45) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM105216 (US8580778, 2) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ... | US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3591 (US8524699, 7) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 880 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3623 (US8524699, 28) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 890 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109271 (US8609698, 65) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109269 (US8609698, 18) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3629 (US8524699, 46) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 930 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118337 (US8653111, 61) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3643 (US8524699, 44) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118334 (US8653111, 50) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118336 (US8653111, 60) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109272 (US8609698, 80) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3644 (US8524699, 55) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118343 (US8653111, 101) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118332 (US8653111, 43) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118340 (US8653111, 83) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118335 (US8653111, 55) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3698 (US8524699, 22) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3723 (US8524699, 6) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118342 (US8653111, 91) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109270 (US8609698, 22) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109273 (US8609698, 89) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3734 (US8524699, 26) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109267 (US8609698, 8) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109266 (US8609698, 5) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Guanylate cyclase soluble subunit alpha-1 (Homo sapiens (Human)) | BDBM281728 ((+)-3-(4-Chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Institut de Biologie Structurale | Assay Description Soluble guanylate cyclase (sGC) converts on stimulation GTP into cGMP and pyrophosphate (PPi). PPi is detected with the aid of the assay described be... | J Med Chem 51: 1115-25 (2008) BindingDB Entry DOI: 10.7270/Q27083RX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Guanylate cyclase soluble subunit alpha-1 (Homo sapiens (Human)) | BDBM281728 ((+)-3-(4-Chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 89 | n/a | n/a | n/a | n/a |
Institut de Biologie Structurale | Assay Description Soluble guanylate cyclase (sGC) converts on stimulation GTP into cGMP and pyrophosphate (PPi). PPi is detected with the aid of the assay described be... | J Med Chem 51: 1115-25 (2008) BindingDB Entry DOI: 10.7270/Q27083RX | |||||||||||
More data for this Ligand-Target Pair |
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