Compile Data Set for Download or QSAR

Found 111 hits with Last Name = 'schwandner' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373826 (CHEMBL256470) Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(Cl)c1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C20H23Cl2N5O2S2/c1-13-11-30-19-18(13)23-12-24-20(19)25-14(2)10-26-5-7-27(8-6-26)31(28,29)15-3-4-16(21)17(22)9-15/h3-4,9,11-12,14H,5-8,10H2,1-2H3,(H,23,24,25)/t14-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373827 (CHEMBL270865) Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1cccc(Cl)c1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C20H24ClN5O2S2/c1-14-12-29-19-18(14)22-13-23-20(19)24-15(2)11-25-6-8-26(9-7-25)30(27,28)17-5-3-4-16(21)10-17/h3-5,10,12-13,15H,6-9,11H2,1-2H3,(H,22,23,24)/t15-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 3 (Homo sapiens (Human))	BDBM50373831 (CHEMBL272087) Show SMILES COc1cc(OC)cc(c1)C(=O)N(CCCc1ccccc1)Cc1ccc(Oc2ccccc2C(O)=O)cc1 Show InChI InChI=1S/C32H31NO6/c1-37-27-19-25(20-28(21-27)38-2)31(34)33(18-8-11-23-9-4-3-5-10-23)22-24-14-16-26(17-15-24)39-30-13-7-6-12-29(30)32(35)36/h3-7,9-10,12-17,19-21H,8,11,18,22H2,1-2H3,(H,35,36)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM50373818 (CHEMBL404575) Show SMILES CC(OC(=O)Nc1c(C)noc1-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C19H18N2O3/c1-13-17(18(24-21-13)16-11-7-4-8-12-16)20-19(22)23-14(2)15-9-5-3-6-10-15/h3-12,14H,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA1 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373815 (CHEMBL401756) Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C21H27N5O2S2/c1-15-4-6-18(7-5-15)30(27,28)26-10-8-25(9-11-26)12-17(3)24-21-20-19(22-14-23-21)16(2)13-29-20/h4-7,13-14,17H,8-12H2,1-3H3,(H,22,23,24)/t17-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373817 (CHEMBL404452) Show SMILES C[C@@H](CN1CCN(CC1)c1ccccc1C)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C21H27N5S/c1-15-6-4-5-7-18(15)26-10-8-25(9-11-26)12-17(3)24-21-20-19(22-14-23-21)16(2)13-27-20/h4-7,13-14,17H,8-12H2,1-3H3,(H,22,23,24)/t17-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373828 (CHEMBL427893) Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1cccc(C)c1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C21H27N5O2S2/c1-15-5-4-6-18(11-15)30(27,28)26-9-7-25(8-10-26)12-17(3)24-21-20-19(22-14-23-21)16(2)13-29-20/h4-6,11,13-14,17H,7-10,12H2,1-3H3,(H,22,23,24)/t17-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305909 ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(methylth...) Show SMILES CSc1cnc(NC(=O)[C@H](c2ccc(Cl)cc2)C(C)(C)C)s1 |r| Show InChI InChI=1S/C16H19ClN2OS2/c1-16(2,3)13(10-5-7-11(17)8-6-10)14(20)19-15-18-9-12(21-4)22-15/h5-9,13H,1-4H3,(H,18,19,20)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305980 ((S)-2-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)-3-...) Show SMILES CC(C)[C@H](C(=O)Nc1ncc(F)s1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C14H14ClFN2OS/c1-8(2)12(9-3-5-10(15)6-4-9)13(19)18-14-17-7-11(16)20-14/h3-8,12H,1-2H3,(H,17,18,19)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305923 ((S)-2-(4-chlorophenyl)-4-methyl-N-(thiazol-2-yl)pe...) Show SMILES CC(C)C[C@H](C(=O)Nc1nccs1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H17ClN2OS/c1-10(2)9-13(11-3-5-12(16)6-4-11)14(19)18-15-17-7-8-20-15/h3-8,10,13H,9H2,1-2H3,(H,17,18,19)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305906 ((S)-N-(5-bromothiazol-2-yl)-2-(4-chlorophenyl)-3,3...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(Br)s1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H16BrClN2OS/c1-15(2,3)12(9-4-6-10(17)7-5-9)13(20)19-14-18-8-11(16)21-14/h4-8,12H,1-3H3,(H,18,19,20)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305981 ((S)-2-(4-chlorophenyl)-N-(5-chlorothiazol-2-yl)-3-...) Show SMILES CC(C)[C@H](C(=O)Nc1ncc(Cl)s1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C14H14Cl2N2OS/c1-8(2)12(9-3-5-10(15)6-4-9)13(19)18-14-17-7-11(16)20-14/h3-8,12H,1-2H3,(H,17,18,19)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305904 ((S)-2-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)-3,...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(F)s1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H16ClFN2OS/c1-15(2,3)12(9-4-6-10(16)7-5-9)13(20)19-14-18-8-11(17)21-14/h4-8,12H,1-3H3,(H,18,19,20)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305974 ((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...) Show SMILES CC(C)[C@H](C(=O)Nc1nccs1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305911 ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthi...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)-c1ccccc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C21H21ClN2OS/c1-21(2,3)18(15-9-11-16(22)12-10-15)19(25)24-20-23-13-17(26-20)14-7-5-4-6-8-14/h4-13,18H,1-3H3,(H,23,24,25)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373829 (CHEMBL429681) Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1ccccc1C)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C21H27N5O2S2/c1-15-6-4-5-7-18(15)30(27,28)26-10-8-25(9-11-26)12-17(3)24-21-20-19(22-14-23-21)16(2)13-29-20/h4-7,13-14,17H,8-12H2,1-3H3,(H,22,23,24)/t17-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373821 (CHEMBL401747) Show SMILES C[C@@H](CN1CCN(CC1)c1ccccc1C)Nc1nc(nc2ccccc12)C(F)(F)F Show InChI InChI=1S/C23H26F3N5/c1-16-7-3-6-10-20(16)31-13-11-30(12-14-31)15-17(2)27-21-18-8-4-5-9-19(18)28-22(29-21)23(24,25)26/h3-10,17H,11-15H2,1-2H3,(H,27,28,29)/t17-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305973 (2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)butana...) Show SMILES CC(C)C(C(=O)Nc1nccs1)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305979 ((S)-2-(4-chlorophenyl)-3-methyl-N-(5-methylthiazol...) Show SMILES CC(C)[C@H](C(=O)Nc1ncc(C)s1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H17ClN2OS/c1-9(2)13(11-4-6-12(16)7-5-11)14(19)18-15-17-8-10(3)20-15/h4-9,13H,1-3H3,(H,17,18,19)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305905 ((S)-2-(4-chlorophenyl)-N-(5-chlorothiazol-2-yl)-3,...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(Cl)s1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H16Cl2N2OS/c1-15(2,3)12(9-4-6-10(16)7-5-9)13(20)19-14-18-8-11(17)21-14/h4-8,12H,1-3H3,(H,18,19,20)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305926 ((S)-2-(4-chlorophenyl)-N-(thiazol-2-yl)pent-4-enam...) Show SMILES Clc1ccc(cc1)[C@H](CC=C)C(=O)Nc1nccs1 |r| Show InChI InChI=1S/C14H13ClN2OS/c1-2-3-12(10-4-6-11(15)7-5-10)13(18)17-14-16-8-9-19-14/h2,4-9,12H,1,3H2,(H,16,17,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305950 ((S)-2-(4-chlorophenyl)-N-(6-fluoropyridin-2-yl)-3-...) Show SMILES CC(C)[C@H](C(=O)Nc1cccc(F)n1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C16H16ClFN2O/c1-10(2)15(11-6-8-12(17)9-7-11)16(21)20-14-5-3-4-13(18)19-14/h3-10,15H,1-2H3,(H,19,20,21)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305933 ((S)-2-cyclopropyl-N-(5-fluorothiazol-2-yl)-2-(4-(t...) Show SMILES Fc1cnc(NC(=O)[C@@H](C2CC2)c2ccc(cc2)C(F)(F)F)s1 |r| Show InChI InChI=1S/C15H12F4N2OS/c16-11-7-20-14(23-11)21-13(22)12(8-1-2-8)9-3-5-10(6-4-9)15(17,18)19/h3-8,12H,1-2H2,(H,20,21,22)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305917 ((S)-2-(4-chlorophenyl)-N-(5-(1,1,1,3,3,3-hexafluor...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)C(O)(C(F)(F)F)C(F)(F)F)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C18H17ClF6N2O2S/c1-15(2,3)12(9-4-6-10(19)7-5-9)13(28)27-14-26-8-11(30-14)16(29,17(20,21)22)18(23,24)25/h4-8,12,29H,1-3H3,(H,26,27,28)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305922 ((S)-2-(4-chlorophenyl)-2-cyclopropyl-N-(5-fluoroth...) Show SMILES Fc1cnc(NC(=O)[C@@H](C2CC2)c2ccc(Cl)cc2)s1 |r| Show InChI InChI=1S/C14H12ClFN2OS/c15-10-5-3-9(4-6-10)12(8-1-2-8)13(19)18-14-17-7-11(16)20-14/h3-8,12H,1-2H2,(H,17,18,19)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373814 (CHEMBL270877) Show SMILES COc1ccccc1N1CCN(C[C@H](C)Nc2nc(nc3ccccc23)C(F)(F)F)CC1 Show InChI InChI=1S/C23H26F3N5O/c1-16(15-30-11-13-31(14-12-30)19-9-5-6-10-20(19)32-2)27-21-17-7-3-4-8-18(17)28-22(29-21)23(24,25)26/h3-10,16H,11-15H2,1-2H3,(H,27,28,29)/t16-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305951 ((S)-2-(4-chlorophenyl)-N-(5-fluoropyridin-2-yl)-3-...) Show SMILES CC(C)[C@H](C(=O)Nc1ccc(F)cn1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C16H16ClFN2O/c1-10(2)15(11-3-5-12(17)6-4-11)16(21)20-14-8-7-13(18)9-19-14/h3-10,15H,1-2H3,(H,19,20,21)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305949 ((S)-2-(4-chlorophenyl)-3-methyl-N-(pyridin-2-yl)bu...) Show SMILES CC(C)[C@H](C(=O)Nc1ccccn1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C16H17ClN2O/c1-11(2)15(12-6-8-13(17)9-7-12)16(20)19-14-5-3-4-10-18-14/h3-11,15H,1-2H3,(H,18,19,20)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305969 ((S)-2-(4-chlorophenyl)-3-methyl-N-(4-methylthiazol...) Show SMILES CC(C)[C@H](C(=O)Nc1nc(C)cs1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H17ClN2OS/c1-9(2)13(11-4-6-12(16)7-5-11)14(19)18-15-17-10(3)8-20-15/h4-9,13H,1-3H3,(H,17,18,19)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305930 (1-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)cyclobu...) Show SMILES Fc1cnc(NC(=O)C2(CCC2)c2ccc(Cl)cc2)s1 Show InChI InChI=1S/C14H12ClFN2OS/c15-10-4-2-9(3-5-10)14(6-1-7-14)12(19)18-13-17-8-11(16)20-13/h2-5,8H,1,6-7H2,(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305908 ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(trifluor...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)C(F)(F)F)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C16H16ClF3N2OS/c1-15(2,3)12(9-4-6-10(17)7-5-9)13(23)22-14-21-8-11(24-14)16(18,19)20/h4-8,12H,1-3H3,(H,21,22,23)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305982 ((S)-2-(4-chlorophenyl)-3-methyl-N-(5-(trifluoromet...) Show SMILES CC(C)[C@H](C(=O)Nc1ncc(s1)C(F)(F)F)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H14ClF3N2OS/c1-8(2)12(9-3-5-10(16)6-4-9)13(22)21-14-20-7-11(23-14)15(17,18)19/h3-8,12H,1-2H3,(H,20,21,22)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305907 ((S)-2-(4-chlorophenyl)-N-(5-cyanothiazol-2-yl)-3,3...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)C#N)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C16H16ClN3OS/c1-16(2,3)13(10-4-6-11(17)7-5-10)14(21)20-15-19-9-12(8-18)22-15/h4-7,9,13H,1-3H3,(H,19,20,21)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305913 ((S)-2-(4-chlorophenyl)-N-(5-(dimethylamino)thiazol...) Show SMILES CN(C)c1cnc(NC(=O)[C@H](c2ccc(Cl)cc2)C(C)(C)C)s1 |r| Show InChI InChI=1S/C17H22ClN3OS/c1-17(2,3)14(11-6-8-12(18)9-7-11)15(22)20-16-19-10-13(23-16)21(4)5/h6-10,14H,1-5H3,(H,19,20,22)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305914 ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-morpholin...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)N1CCOCC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H24ClN3O2S/c1-19(2,3)16(13-4-6-14(20)7-5-13)17(24)22-18-21-12-15(26-18)23-8-10-25-11-9-23/h4-7,12,16H,8-11H2,1-3H3,(H,21,22,24)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373819 (CHEMBL402218) Show SMILES CC(CN1CCN(CC1)c1ccc(F)cc1)Nc1nc(nc2ccccc12)C1CC1 |w:1.0| Show InChI InChI=1S/C24H28FN5/c1-17(16-29-12-14-30(15-13-29)20-10-8-19(25)9-11-20)26-24-21-4-2-3-5-22(21)27-23(28-24)18-6-7-18/h2-5,8-11,17-18H,6-7,12-16H2,1H3,(H,26,27,28)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 assessed as inhibition of LPA-induced Ca2+ flux				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305978 ((S)-2-(4-chlorophenyl)-N-(4,5-dimethylthiazol-2-yl...) Show SMILES CC(C)[C@H](C(=O)Nc1nc(C)c(C)s1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C16H19ClN2OS/c1-9(2)14(12-5-7-13(17)8-6-12)15(20)19-16-18-10(3)11(4)21-16/h5-9,14H,1-4H3,(H,18,19,20)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373830 (CHEMBL401543) Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)Cc1ccccc1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C21H27N5O2S2/c1-16-13-29-20-19(16)22-15-23-21(20)24-17(2)12-25-8-10-26(11-9-25)30(27,28)14-18-6-4-3-5-7-18/h3-7,13,15,17H,8-12,14H2,1-2H3,(H,22,23,24)/t17-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305957 ((S)-2-(4-chlorophenyl)-3-methyl-N-(5-(trifluoromet...) Show SMILES CC(C)[C@H](C(=O)Nc1nnc(s1)C(F)(F)F)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C14H13ClF3N3OS/c1-7(2)10(8-3-5-9(15)6-4-8)11(22)19-13-21-20-12(23-13)14(16,17)18/h3-7,10H,1-2H3,(H,19,21,22)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305958 ((S)-2-(4-chlorophenyl)-3-methyl-N-(1,2,4-thiadiazo...) Show SMILES CC(C)[C@H](C(=O)Nc1ncns1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C13H14ClN3OS/c1-8(2)11(9-3-5-10(14)6-4-9)12(18)17-13-15-7-16-19-13/h3-8,11H,1-2H3,(H,15,16,17,18)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305901 ((S)-2-(4-chlorophenyl)-N-(5-cyanothiazol-2-yl)-3-m...) Show SMILES CC(C)[C@H](C(=O)Nc1ncc(s1)C#N)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H14ClN3OS/c1-9(2)13(10-3-5-11(16)6-4-10)14(20)19-15-18-8-12(7-17)21-15/h3-6,8-9,13H,1-2H3,(H,18,19,20)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305902 ((S)-methyl 2-(2-(4-chlorophenyl)-3-methylbutanamid...) Show SMILES COC(=O)c1cnc(NC(=O)[C@@H](C(C)C)c2ccc(Cl)cc2)s1 |r| Show InChI InChI=1S/C16H17ClN2O3S/c1-9(2)13(10-4-6-11(17)7-5-10)14(20)19-16-18-8-12(23-16)15(21)22-3/h4-9,13H,1-3H3,(H,18,19,20)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305964 ((S)-2-(4-chlorophenyl)-N-(4,5-dihydrothiazol-2-yl)...) Show SMILES CC(C)[C@H](C(=O)NC1=NCCS1)c1ccc(Cl)cc1 |r,t:7| Show InChI InChI=1S/C14H17ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-6,9,12H,7-8H2,1-2H3,(H,16,17,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305954 ((S)-2-(4-chlorophenyl)-3-methyl-N-(pyridazin-3-yl)...) Show SMILES CC(C)[C@H](C(=O)Nc1cccnn1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H16ClN3O/c1-10(2)14(11-5-7-12(16)8-6-11)15(20)18-13-4-3-9-17-19-13/h3-10,14H,1-2H3,(H,18,19,20)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305916 ((S)-2-(4-Chloro-phenyl)-N-[5-(1,1-dioxo-1lambda*6*...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)N1CCS(=O)(=O)CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H24ClN3O3S2/c1-19(2,3)16(13-4-6-14(20)7-5-13)17(24)22-18-21-12-15(27-18)23-8-10-28(25,26)11-9-23/h4-7,12,16H,8-11H2,1-3H3,(H,21,22,24)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305966 (CHEMBL609852 | rac-N-(benzo[d]thiazol-2-yl)-2-(4-c...) Show SMILES CC(C)C(C(=O)Nc1nc2ccccc2s1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H17ClN2OS/c1-11(2)16(12-7-9-13(19)10-8-12)17(22)21-18-20-14-5-3-4-6-15(14)23-18/h3-11,16H,1-2H3,(H,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 2 (Homo sapiens (Human))	BDBM50373820 (CHEMBL270878) Show SMILES COc1ccccc1N1CCN(C[C@H](C)Nc2nc(nc3ccccc23)C2CC2)CC1 Show InChI InChI=1S/C25H31N5O/c1-18(17-29-13-15-30(16-14-29)22-9-5-6-10-23(22)31-2)26-25-20-7-3-4-8-21(20)27-24(28-25)19-11-12-19/h3-10,18-19H,11-17H2,1-2H3,(H,26,27,28)/t18-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay				Bioorg Med Chem Lett 18: 1037-41 (2008) Article DOI: 10.1016/j.bmcl.2007.12.024 BindingDB Entry DOI: 10.7270/Q2JQ11W8
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305910 ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(methylsu...) Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)S(C)(=O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C16H19ClN2O3S2/c1-16(2,3)13(10-5-7-11(17)8-6-10)14(20)19-15-18-9-12(23-15)24(4,21)22/h5-9,13H,1-4H3,(H,18,19,20)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305915 ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(4-methyl...) Show SMILES CN1CCN(CC1)c1cnc(NC(=O)[C@H](c2ccc(Cl)cc2)C(C)(C)C)s1 |r| Show InChI InChI=1S/C20H27ClN4OS/c1-20(2,3)17(14-5-7-15(21)8-6-14)18(26)23-19-22-13-16(27-19)25-11-9-24(4)10-12-25/h5-8,13,17H,9-12H2,1-4H3,(H,22,23,26)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50305967 ((S)-N-(5-chlorobenzo[d]oxazol-2-yl)-2-(4-chlorophe...) Show SMILES CC(C)[C@H](C(=O)Nc1nc2cc(Cl)ccc2o1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C18H16Cl2N2O2/c1-10(2)16(11-3-5-12(19)6-4-11)17(23)22-18-21-14-9-13(20)7-8-15(14)24-18/h3-10,16H,1-2H3,(H,21,22,23)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair

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