Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118338 (US8653111, 62) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3527 (US8524699, 18) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171824 (US9085572, 34) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118341 (US8653111, 85) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109268 (US8609698, 10) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118328 (US8653111, 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118344 (US8653111, 103) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118346 (US8653111, 129) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171821 (US9085572, 6) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 430 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3543 (US8524699, 16) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 480 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118339 (US8653111, 72) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118329 (US8653111, 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118331 (US8653111, 17) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118347 (US8653111, 166) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171827 (US9085572, 46) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 700 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3555 (US8524699, 3) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 700 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118345 (US8653111, 113) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118330 (US8653111, 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171823 (US9085572, 26) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 760 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118333 (US8653111, 45) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171822 (US9085572, 23) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 860 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3591 (US8524699, 7) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 880 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3623 (US8524699, 28) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 890 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109271 (US8609698, 65) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109269 (US8609698, 18) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3629 (US8524699, 46) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 930 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50324535 (3-{[9-(Dimethylamino)nonanoyl](hydroxy)amino}propa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118337 (US8653111, 61) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3643 (US8524699, 44) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50324529 (3-({9-[Benzyl(methyl)]amino}nonanoyl(hydroxy)amino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118336 (US8653111, 60) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118334 (US8653111, 50) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171826 (US9085572, 43) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50324534 (3-{[8-(Dimethylamino)octanoyl](hydroxy)amino}propa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of human recombinant PHD1 expressed in Sf9 cells by time-resolved fluorescence assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50324536 (3-{[10-(Dimethylamino)decanoyl](hydroxy)amino}prop...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM109272 (US8609698, 80) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ... | US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50324530 (CHEMBL1215590 | tert-Butyl 3-({Hydroxy[9-(methylam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118343 (US8653111, 101) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human)) | BDBM3644 (US8524699, 55) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118332 (US8653111, 43) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118340 (US8653111, 83) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171829 (US9085572, 48) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171830 (US9085572, 50) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM118335 (US8653111, 55) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4A (Homo sapiens (Human)) | BDBM50324529 (3-({9-[Benzyl(methyl)]amino}nonanoyl(hydroxy)amino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50324527 (4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl hydroxylase EGLN2 (Homo sapiens (Human)) | BDBM26106 (CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibition of human recombinant PHD1 expressed in Sf9 cells by time-resolved fluorescence assay | J Med Chem 53: 5629-38 (2010) Article DOI: 10.1021/jm1003655 BindingDB Entry DOI: 10.7270/Q2N87B02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171828 (US9085572, 47) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM171825 (US9085572, 35) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i... | US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 95 total ) | Next | Last >> |