Found 73 hits with Last Name = 'nishitoba' and Initial = 't' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM3032
(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)Show InChI InChI=1S/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cells |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141817
(CHEMBL171509 | [1-(2-{4-[4-(4-tert-Butyl-phenylami...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCN1CCC(CO)CC1 Show InChI InChI=1S/C34H41N3O4/c1-34(2,3)25-5-7-26(8-6-25)36-27-9-11-28(12-10-27)41-31-13-16-35-30-22-33(32(39-4)21-29(30)31)40-20-19-37-17-14-24(23-38)15-18-37/h5-13,16,21-22,24,36,38H,14-15,17-20,23H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50290834
(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)Show InChI InChI=1S/C19H19NO5/c1-21-16-6-5-12(9-17(16)22-2)25-15-7-8-20-14-11-19(24-4)18(23-3)10-13(14)15/h5-11H,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of Platelet-derived growth factor receptor beta (PDGF beta-R) |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141829
((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)c2cc1OC Show InChI InChI=1S/C27H28N2O3/c1-27(2,3)18-6-8-19(9-7-18)29-20-10-12-21(13-11-20)32-24-14-15-28-23-17-26(31-5)25(30-4)16-22(23)24/h6-17,29H,1-5H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141822
((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3F)c2cc1OC Show InChI InChI=1S/C27H27FN2O3/c1-27(2,3)17-6-8-18(9-7-17)30-19-10-11-24(21(28)14-19)33-23-12-13-29-22-16-26(32-5)25(31-4)15-20(22)23/h6-16,30H,1-5H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141819
((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)c(F)c3)c2cc1OC Show InChI InChI=1S/C27H27FN2O3/c1-27(2,3)17-6-8-18(9-7-17)30-22-11-10-19(14-21(22)28)33-24-12-13-29-23-16-26(32-5)25(31-4)15-20(23)24/h6-16,30H,1-5H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Mus musculus (mouse)) | BDBM50290834
(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)Show InChI InChI=1S/C19H19NO5/c1-21-16-6-5-12(9-17(16)22-2)25-15-7-8-20-14-11-19(24-4)18(23-3)10-13(14)15/h5-11H,1-4H3 | MMDB
KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of platelet-derived growth factor receptor (PDGF-R) in human aortic smooth muscle cells |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141812
(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-2-fluoro-phe...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3F)ccnc2cc1OCCNCCO Show InChI InChI=1S/C30H34FN3O4/c1-30(2,3)20-5-7-21(8-6-20)34-22-9-10-27(24(31)17-22)38-26-11-12-33-25-19-29(28(36-4)18-23(25)26)37-16-14-32-13-15-35/h5-12,17-19,32,34-35H,13-16H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50290838
(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)Show InChI InChI=1S/C16H13BrN2O3/c1-20-14-7-12-13(8-15(14)21-2)18-9-19-16(12)22-11-5-3-4-10(17)6-11/h3-9H,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cells |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141813
(1-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-meth...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCC(O)CN1CCOCC1 Show InChI InChI=1S/C33H39N3O5/c1-33(2,3)23-5-7-24(8-6-23)35-25-9-11-27(12-10-25)41-30-13-14-34-29-20-32(31(38-4)19-28(29)30)40-22-26(37)21-36-15-17-39-18-16-36/h5-14,19-20,26,35,37H,15-18,21-22H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141823
(2-[(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCN(CCO)CCO Show InChI InChI=1S/C32H39N3O5/c1-32(2,3)23-5-7-24(8-6-23)34-25-9-11-26(12-10-25)40-29-13-14-33-28-22-31(30(38-4)21-27(28)29)39-20-17-35(15-18-36)16-19-37/h5-14,21-22,34,36-37H,15-20H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141809
(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCNCCO Show InChI InChI=1S/C30H35N3O4/c1-30(2,3)21-5-7-22(8-6-21)33-23-9-11-24(12-10-23)37-27-13-14-32-26-20-29(28(35-4)19-25(26)27)36-18-16-31-15-17-34/h5-14,19-20,31,33-34H,15-18H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibition of vascular endothelial growth factor receptor 2 autophosphorylation in intact cells |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141809
(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCNCCO Show InChI InChI=1S/C30H35N3O4/c1-30(2,3)21-5-7-22(8-6-21)33-23-9-11-24(12-10-23)37-27-13-14-32-26-20-29(28(35-4)19-25(26)27)36-18-16-31-15-17-34/h5-14,19-20,31,33-34H,15-18H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141810
((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)c(C)c3)c2cc1OC Show InChI InChI=1S/C28H30N2O3/c1-18-15-21(11-12-23(18)30-20-9-7-19(8-10-20)28(2,3)4)33-25-13-14-29-24-17-27(32-6)26(31-5)16-22(24)25/h7-17,30H,1-6H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50141809
(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCNCCO Show InChI InChI=1S/C30H35N3O4/c1-30(2,3)21-5-7-22(8-6-21)33-23-9-11-24(12-10-23)37-27-13-14-32-26-20-29(28(35-4)19-25(26)27)36-18-16-31-15-17-34/h5-14,19-20,31,33-34H,15-18H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibition of c-Kit autophosphorylation in intact cells |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290834
(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)Show InChI InChI=1S/C19H19NO5/c1-21-16-6-5-12(9-17(16)22-2)25-15-7-8-20-14-11-19(24-4)18(23-3)10-13(14)15/h5-11H,1-4H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141832
((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)c(C)c3C)c2cc1OC Show InChI InChI=1S/C29H32N2O3/c1-18-19(2)25(13-12-23(18)31-21-10-8-20(9-11-21)29(3,4)5)34-26-14-15-30-24-17-28(33-7)27(32-6)16-22(24)26/h8-17,31H,1-7H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50290834
(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)Show InChI InChI=1S/C19H19NO5/c1-21-16-6-5-12(9-17(16)22-2)25-15-7-8-20-14-11-19(24-4)18(23-3)10-13(14)15/h5-11H,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of epidermal growth factor receptor (EGF-R) in A431 cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141821
((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)Show SMILES COc1cc2nccc(Oc3ccc(cc3)C(=O)c3ccc(cc3)C(C)(C)C)c2cc1OC Show InChI InChI=1S/C28H27NO4/c1-28(2,3)20-10-6-18(7-11-20)27(30)19-8-12-21(13-9-19)33-24-14-15-29-23-17-26(32-5)25(31-4)16-22(23)24/h6-17H,1-5H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141816
(1-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-meth...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCC(O)CN1CCCCC1 Show InChI InChI=1S/C34H41N3O4/c1-34(2,3)24-8-10-25(11-9-24)36-26-12-14-28(15-13-26)41-31-16-17-35-30-21-33(32(39-4)20-29(30)31)40-23-27(38)22-37-18-6-5-7-19-37/h8-17,20-21,27,36,38H,5-7,18-19,22-23H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141814
(CHEMBL276125 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)C)cc3)c2cc1OC Show InChI InChI=1S/C26H26N2O3/c1-17(2)18-5-7-19(8-6-18)28-20-9-11-21(12-10-20)31-24-13-14-27-23-16-26(30-4)25(29-3)15-22(23)24/h5-17,28H,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141824
((4-tert-Butyl-phenyl)-{4-[6-methoxy-7-(2-morpholin...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCN1CCOCC1 Show InChI InChI=1S/C32H37N3O4/c1-32(2,3)23-5-7-24(8-6-23)34-25-9-11-26(12-10-25)39-29-13-14-33-28-22-31(30(36-4)21-27(28)29)38-20-17-35-15-18-37-19-16-35/h5-14,21-22,34H,15-20H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141811
(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-3-fluoro-phe...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)c(F)c3)ccnc2cc1OCCNCCO Show InChI InChI=1S/C30H34FN3O4/c1-30(2,3)20-5-7-21(8-6-20)34-25-10-9-22(17-24(25)31)38-27-11-12-33-26-19-29(28(36-4)18-23(26)27)37-16-14-32-13-15-35/h5-12,17-19,32,34-35H,13-16H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141831
((4-tert-Butyl-phenyl)-{4-[6-methoxy-7-(3-piperidin...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C34H41N3O3/c1-34(2,3)25-9-11-26(12-10-25)36-27-13-15-28(16-14-27)40-31-17-18-35-30-24-33(32(38-4)23-29(30)31)39-22-8-21-37-19-6-5-7-20-37/h9-18,23-24,36H,5-8,19-22H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50290836
((3-Bromo-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-ami...)Show InChI InChI=1S/C17H15BrN2O2/c1-21-16-9-13-14(20-12-5-3-4-11(18)8-12)6-7-19-15(13)10-17(16)22-2/h3-10H,1-2H3,(H,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cells |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290847
(6,7-Dimethoxy-4-(3-methoxy-phenoxy)-quinoline | CH...)Show InChI InChI=1S/C18H17NO4/c1-20-12-5-4-6-13(9-12)23-16-7-8-19-15-11-18(22-3)17(21-2)10-14(15)16/h4-11H,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141827
(4-[4-(4-tert-Butyl-phenoxy)-phenoxy]-6,7-dimethoxy...)Show SMILES COc1cc2nccc(Oc3ccc(Oc4ccc(cc4)C(C)(C)C)cc3)c2cc1OC Show InChI InChI=1S/C27H27NO4/c1-27(2,3)18-6-8-19(9-7-18)31-20-10-12-21(13-11-20)32-24-14-15-28-23-17-26(30-5)25(29-4)16-22(23)24/h6-17H,1-5H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50141809
(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCNCCO Show InChI InChI=1S/C30H35N3O4/c1-30(2,3)21-5-7-22(8-6-21)33-23-9-11-24(12-10-23)37-27-13-14-32-26-20-29(28(35-4)19-25(26)27)36-18-16-31-15-17-34/h5-14,19-20,31,33-34H,15-18H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description Inhibition of PDGF-receptor autophosphorylation in intact cells |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290850
(3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenol | CHEMBL...)Show InChI InChI=1S/C17H15NO4/c1-20-16-9-13-14(10-17(16)21-2)18-7-6-15(13)22-12-5-3-4-11(19)8-12/h3-10,19H,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290837
(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinazolin...)Show InChI InChI=1S/C18H18N2O5/c1-21-14-6-5-11(7-15(14)22-2)25-18-12-8-16(23-3)17(24-4)9-13(12)19-10-20-18/h5-10H,1-4H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290848
(6,7-Dimethoxy-4-(2-methoxy-phenoxy)-quinoline | CH...)Show InChI InChI=1S/C18H17NO4/c1-20-15-6-4-5-7-16(15)23-14-8-9-19-13-11-18(22-3)17(21-2)10-12(13)14/h4-11H,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290844
(6,7-Dimethoxy-4-(3-nitro-phenoxy)-quinoline | CHEM...)Show SMILES COc1cc2nccc(Oc3cccc(c3)[N+]([O-])=O)c2cc1OC Show InChI InChI=1S/C17H14N2O5/c1-22-16-9-13-14(10-17(16)23-2)18-7-6-15(13)24-12-5-3-4-11(8-12)19(20)21/h3-10H,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290853
(6,7-Dimethoxy-4-phenoxy-quinoline | CHEMBL327534)Show InChI InChI=1S/C17H15NO3/c1-19-16-10-13-14(11-17(16)20-2)18-9-8-15(13)21-12-6-4-3-5-7-12/h3-11H,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141826
(CHEMBL354830 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)Show SMILES COc1ccc(Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cc1 Show InChI InChI=1S/C24H22N2O4/c1-27-18-8-4-16(5-9-18)26-17-6-10-19(11-7-17)30-22-12-13-25-21-15-24(29-3)23(28-2)14-20(21)22/h4-15,26H,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141830
(4-[4-(4-tert-Butyl-benzyl)-phenoxy]-6,7-dimethoxy-...)Show SMILES COc1cc2nccc(Oc3ccc(Cc4ccc(cc4)C(C)(C)C)cc3)c2cc1OC Show InChI InChI=1S/C28H29NO3/c1-28(2,3)21-10-6-19(7-11-21)16-20-8-12-22(13-9-20)32-25-14-15-29-24-18-27(31-5)26(30-4)17-23(24)25/h6-15,17-18H,16H2,1-5H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290841
(4-(3-Fluoro-phenoxy)-6,7-dimethoxy-quinoline | CHE...)Show InChI InChI=1S/C17H14FNO3/c1-20-16-9-13-14(10-17(16)21-2)19-7-6-15(13)22-12-5-3-4-11(18)8-12/h3-10H,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290846
(3-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine | C...)Show InChI InChI=1S/C17H16N2O3/c1-20-16-9-13-14(10-17(16)21-2)19-7-6-15(13)22-12-5-3-4-11(18)8-12/h3-10H,18H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290842
(6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline | CH...)Show InChI InChI=1S/C18H17NO4/c1-20-12-4-6-13(7-5-12)23-16-8-9-19-15-11-18(22-3)17(21-2)10-14(15)16/h4-11H,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50290839
(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)Show InChI InChI=1S/C17H14BrNO3/c1-20-16-9-13-14(10-17(16)21-2)19-7-6-15(13)22-12-5-3-4-11(18)8-12/h3-10H,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cells |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290849
((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-y...)Show InChI InChI=1S/C19H20N2O4/c1-22-16-6-5-12(9-17(16)23-2)21-14-7-8-20-15-11-19(25-4)18(24-3)10-13(14)15/h5-11H,1-4H3,(H,20,21) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50290835
((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...)Show InChI InChI=1S/C18H19N3O4/c1-22-14-6-5-11(7-15(14)23-2)21-18-12-8-16(24-3)17(25-4)9-13(12)19-10-20-18/h5-10H,1-4H3,(H,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cells |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141828
((4-tert-Butyl-cyclohexyl)-[4-(6,7-dimethoxy-quinol...)Show SMILES COc1cc2nccc(Oc3ccc(NC4CCC(CC4)C(C)(C)C)cc3)c2cc1OC |(1.64,-5.73,;2.98,-6.5,;4.31,-5.73,;5.66,-6.49,;6.98,-5.73,;8.31,-6.49,;9.65,-5.73,;9.65,-4.19,;8.31,-3.42,;8.31,-1.89,;9.64,-1.12,;9.64,.43,;10.96,1.2,;12.3,.43,;13.64,1.21,;14.98,.44,;16.3,1.23,;17.65,.46,;17.67,-1.08,;16.32,-1.86,;14.99,-1.09,;19.03,-1.85,;20.39,-2.59,;19.79,-.49,;18.28,-3.2,;12.3,-1.12,;10.96,-1.89,;6.98,-4.19,;5.66,-3.42,;4.31,-4.19,;2.98,-3.42,;1.65,-4.2,)| Show InChI InChI=1S/C27H34N2O3/c1-27(2,3)18-6-8-19(9-7-18)29-20-10-12-21(13-11-20)32-24-14-15-28-23-17-26(31-5)25(30-4)16-22(23)24/h10-19,29H,6-9H2,1-5H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290840
(4-(2,3-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)Show InChI InChI=1S/C19H19NO5/c1-21-15-6-5-7-16(19(15)24-4)25-14-8-9-20-13-11-18(23-3)17(22-2)10-12(13)14/h5-11H,1-4H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290835
((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinazolin-4...)Show InChI InChI=1S/C18H19N3O4/c1-22-14-6-5-11(7-15(14)23-2)21-18-12-8-16(24-3)17(25-4)9-13(12)19-10-20-18/h5-10H,1-4H3,(H,19,20,21) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141808
(Biphenyl-4-yl-[4-(6,7-dimethoxy-quinolin-4-yloxy)-...)Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)-c4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C29H24N2O3/c1-32-28-18-25-26(19-29(28)33-2)30-17-16-27(25)34-24-14-12-23(13-15-24)31-22-10-8-21(9-11-22)20-6-4-3-5-7-20/h3-19,31H,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290852
(4-(3,5-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)Show InChI InChI=1S/C19H19NO5/c1-21-12-7-13(22-2)9-14(8-12)25-17-5-6-20-16-11-19(24-4)18(23-3)10-15(16)17/h5-11H,1-4H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290845
(6,7-Dimethoxy-4-m-tolyloxy-quinoline | CHEMBL98839)Show InChI InChI=1S/C18H17NO3/c1-12-5-4-6-13(9-12)22-16-7-8-19-15-11-18(21-3)17(20-2)10-14(15)16/h4-11H,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290843
(4-(3-Ethyl-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)Show InChI InChI=1S/C19H19NO3/c1-4-13-6-5-7-14(10-13)23-17-8-9-20-16-12-19(22-3)18(21-2)11-15(16)17/h5-12H,4H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Rattus norvegicus) | BDBM50290839
(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinoline | CHEM...)Show InChI InChI=1S/C17H14BrNO3/c1-20-16-9-13-14(10-17(16)21-2)19-7-6-15(13)22-12-5-3-4-11(18)8-12/h3-10H,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. |
Bioorg Med Chem Lett 7: 2935-2940 (1997)
Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R |
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50141825
(CHEMBL172746 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)Show InChI InChI=1S/C23H20N2O3/c1-26-22-14-19-20(15-23(22)27-2)24-13-12-21(19)28-18-10-8-17(9-11-18)25-16-6-4-3-5-7-16/h3-15,25H,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line |
Bioorg Med Chem Lett 14: 875-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV |
More data for this Ligand-Target Pair | |